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NVS vs. ONC: Novartis vs. BeOne Medicines Stock Comparison

How do Novartis (NVS) and BeOne Medicines (ONC) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Novartis (NVS) and BeOne Medicines (ONC) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but NVS is classified in Pharmaceuticals while ONC is classified in Biotechnology.

Both Novartis (NVS) and BeOne Medicines (ONC) trade as ADRs — their core financials are comparable, but keep FX, depositary-program fees, and dividend withholding in view for each.

Company profile comparison for Novartis (NVS) and BeOne Medicines (ONC)
Profile ItemNVSONC
NameNovartis AG Sponsored ADRBeOne Medicines Ltd. American Depositary Shares
Country/RegionSwitzerlandSwitzerland
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryPharmaceuticalsBiotechnology
GICS Sub-IndustryPharmaceuticalsBiotechnology
Market Capitalization307.00 billion USD46.49 billion USD
CurrencyUSDUSD
ExchangeNYSENasdaq
Listing DateNovember 7, 1996February 3, 2016
Security TypeADRADR

Price Performance

Cumulative Growth

NVS
ONC
GSPC
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Novartis (NVS) vs. BeOne Medicines (ONC), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Novartis (NVS) and BeOne Medicines (ONC). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Novartis (NVS) and BeOne Medicines (ONC). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Novartis (NVS) and BeOne Medicines (ONC)
MetricNVSONC
Total Return (1Y)32.98%30.59%
Total Return (3Y, Annualized)24.72%30.15%
Total Return (5Y, Annualized)18.80%2.48%

Risk Profile

Drawdown History

NVS
ONC
GSPC
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Novartis (NVS) vs. BeOne Medicines (ONC), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Novartis (NVS) and BeOne Medicines (ONC). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Novartis (NVS) and BeOne Medicines (ONC)
MetricNVSONC
Volatility (1Y, Annualized)27.12%35.90%
Beta (5Y)0.410.59
Max Drawdown (5Y)-20.42%-68.89%
Avg. Volume (3M)2.07M405.29K

Risk-Adjusted Performance

Risk-Return Positioning

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NVS and ONC are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Novartis (NVS) and BeOne Medicines (ONC)
MetricNVSONC
Sharpe Ratio (1Y)1.060.73
Sortino Ratio (1Y)1.461.15

Profitability

ROE (TTM)

Both Novartis (NVS) at 24.33% and BeOne Medicines (ONC) at 18.40% sit in the top peer quartile for ROE, suggesting each generates more profit from shareholders’ equity than typical industry peers.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

24.33%

Max
109.18%
NVS
24.33%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

18.40%

Max
109.18%
ONC
18.40%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Novartis (NVS) vs. BeOne Medicines (ONC): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

For every dollar of sales, both Novartis (NVS) at 17.49% and BeOne Medicines (ONC) at 13.86% retain more as net profit than most peers, landing in the top net margin quartile of their industries.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

17.49%

Max
18.05%
NVS
17.49%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

13.86%

Max
18.05%
ONC
13.86%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Novartis (NVS) vs. BeOne Medicines (ONC): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Novartis (NVS) at 34.27% and BeOne Medicines (ONC) at 22.15% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

34.27%

Max
83.12%
NVS
34.27%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

22.15%

Max
83.12%
ONC
22.15%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Novartis (NVS) vs. BeOne Medicines (ONC): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Novartis (NVS) and BeOne Medicines (ONC)
MetricNVSONC
ROE (TTM)24.33%18.40%
ROA (TTM)10.86%8.42%
Net Margin (TTM)17.49%13.86%
Operating Margin (TTM)34.27%22.15%
Gross Margin (TTM)75.21%89.39%

Growth

Revenue Growth

Both Novartis (NVS) at 9.57% and BeOne Medicines (ONC) at 40.23% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

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Novartis (NVS) vs. BeOne Medicines (ONC): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: Novartis (NVS) reports EPS growth of 21.81%, ranked against its industry; BeOne Medicines (ONC) has no EPS growth figure this period.

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Novartis (NVS) vs. BeOne Medicines (ONC): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Novartis (NVS) and BeOne Medicines (ONC)
MetricNVSONC
Revenue Growth (YoY)9.57%40.23%
Revenue Growth (3Y CAGR)9.25%55.69%
EPS Growth (YoY)21.81%--
EPS Growth (3Y CAGR)31.14%--

Financial Strength

Current Ratio (MRQ)

BeOne Medicines (ONC) at 3.55 keeps current ratio within its industry’s typical mid-range, while Novartis (NVS) at 0.88 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for NVS.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.88

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
NVS
0.88
Min
0.10

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.55

Max
25.13
Q3
12.13
Median
5.52
ONC
3.55
Q1
2.47
Min
0.10
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Novartis (NVS) vs. BeOne Medicines (ONC): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

BeOne Medicines (ONC) at 0.35 carries an industry-typical debt-to-equity mix, while Novartis (NVS) at 1.29 uses more debt funding than most peers.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.29

Max
1.42
NVS
1.29
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.35

Max
1.42
Q3
0.65
ONC
0.35
Median
0.15
Q1
0.02
Min
0.00
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Novartis (NVS) vs. BeOne Medicines (ONC): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Novartis (NVS) and BeOne Medicines (ONC)
MetricNVSONC
Current Ratio (MRQ)0.883.55
Debt / Equity (MRQ)1.290.35
Net Debt / EBITDA1.64-2.80

Dividends

Dividend Yield (TTM)

BeOne Medicines (ONC) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Novartis (NVS) reports a yield of 2.88%, ranking against industry peers normally.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.88%

NVS
2.88%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ONC
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Novartis (NVS) vs. BeOne Medicines (ONC): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

BeOne Medicines (ONC) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Novartis (NVS) reports a payout of 90.46%, ranking against industry peers normally.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

90.46%

NVS
90.46%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ONC
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Novartis (NVS) vs. BeOne Medicines (ONC): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Novartis (NVS) and BeOne Medicines (ONC)
MetricNVSONC
Dividend Yield (TTM)2.88%0.00%
Dividend Payout Ratio (TTM)90.46%0.00%

Valuation

P/E Ratio (TTM)

Novartis (NVS) at 31.02 is near its industry’s usual P/E ratio, while BeOne Medicines (ONC) at 52.17 sits in the richer quartile — ONC needs stronger growth or earnings quality to justify the premium.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

31.02

Max
85.34
Q3
43.46
NVS
31.02
Median
26.69
Q1
13.30
Min
0.07

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

52.17

Max
85.34
ONC
52.17
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
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Novartis (NVS) vs. BeOne Medicines (ONC): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

On P/S ratio, both Novartis (NVS) at 5.35 and BeOne Medicines (ONC) at 7.04 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.35

Max
58.18
Q3
25.77
Median
7.30
NVS
5.35
Q1
3.01
Min
0.01

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

7.04

Max
58.18
Q3
25.77
Median
7.30
ONC
7.04
Q1
3.01
Min
0.01
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Novartis (NVS) vs. BeOne Medicines (ONC): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Both Novartis (NVS) at 8.25 and BeOne Medicines (ONC) at 7.98 carry a premium to book value versus peers, sitting in the upper P/B ratio quartile of their industries.

NVS

Pharmaceuticals, Biotechnology & Life Sciences industry group

8.25

Max
13.53
NVS
8.25
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

7.98

Max
13.53
ONC
7.98
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
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Novartis (NVS) vs. BeOne Medicines (ONC): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Novartis (NVS) and BeOne Medicines (ONC)
MetricNVSONC
P/E Ratio (TTM)31.0252.17
P/S Ratio (TTM)5.357.04
P/B Ratio (MRQ)8.257.98
Free Cash Flow Yield (TTM)3.67%2.21%