NVS vs. ONC: Novartis vs. BeOne Medicines Stock Comparison
How do Novartis (NVS) and BeOne Medicines (ONC) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.
Company Profile
Novartis (NVS) and BeOne Medicines (ONC) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but NVS is classified in Pharmaceuticals while ONC is classified in Biotechnology.
Both Novartis (NVS) and BeOne Medicines (ONC) trade as ADRs — their core financials are comparable, but keep FX, depositary-program fees, and dividend withholding in view for each.
| Profile Item | NVS | ONC |
|---|---|---|
| Name | Novartis AG Sponsored ADR | BeOne Medicines Ltd. American Depositary Shares |
| Country/Region | Switzerland | Switzerland |
| GICS Sector | Health Care | Health Care |
| GICS Industry Group | Pharmaceuticals, Biotechnology & Life Sciences | Pharmaceuticals, Biotechnology & Life Sciences |
| GICS Industry | Pharmaceuticals | Biotechnology |
| GICS Sub-Industry | Pharmaceuticals | Biotechnology |
| Market Capitalization | 307.00 billion USD | 46.49 billion USD |
| Currency | USD | USD |
| Exchange | NYSE | Nasdaq |
| Listing Date | November 7, 1996 | February 3, 2016 |
| Security Type | ADR | ADR |
Price Performance
Cumulative Growth
Trailing Returns
Calendar-Year Returns
Performance Metrics
| Metric | NVS | ONC |
|---|---|---|
| Total Return (1Y) | 32.98% | 30.59% |
| Total Return (3Y, Annualized) | 24.72% | 30.15% |
| Total Return (5Y, Annualized) | 18.80% | 2.48% |
Risk Profile
Drawdown History
Return Distribution
Risk Metrics
| Metric | NVS | ONC |
|---|---|---|
| Volatility (1Y, Annualized) | 27.12% | 35.90% |
| Beta (5Y) | 0.41 | 0.59 |
| Max Drawdown (5Y) | -20.42% | -68.89% |
| Avg. Volume (3M) | 2.07M | 405.29K |
Risk-Adjusted Performance
Risk-Return Positioning
Risk-Adjusted Metrics
| Metric | NVS | ONC |
|---|---|---|
| Sharpe Ratio (1Y) | 1.06 | 0.73 |
| Sortino Ratio (1Y) | 1.46 | 1.15 |
Profitability
ROE (TTM)
Both Novartis (NVS) at 24.33% and BeOne Medicines (ONC) at 18.40% sit in the top peer quartile for ROE, suggesting each generates more profit from shareholders’ equity than typical industry peers.
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
24.33%
- Max
- 109.18%
- NVS
- 24.33%
- Q3
- 6.23%
- Median
- -26.66%
- Q1
- -64.05%
- Min
- -167.77%
ONC
Pharmaceuticals, Biotechnology & Life Sciences industry group
18.40%
- Max
- 109.18%
- ONC
- 18.40%
- Q3
- 6.23%
- Median
- -26.66%
- Q1
- -64.05%
- Min
- -167.77%
Net Margin (TTM)
For every dollar of sales, both Novartis (NVS) at 17.49% and BeOne Medicines (ONC) at 13.86% retain more as net profit than most peers, landing in the top net margin quartile of their industries.
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
17.49%
- Max
- 18.05%
- NVS
- 17.49%
- Q3
- 4.78%
- Median
- 0.00%
- Q1
- -4.14%
- Min
- -17.05%
ONC
Pharmaceuticals, Biotechnology & Life Sciences industry group
13.86%
- Max
- 18.05%
- ONC
- 13.86%
- Q3
- 4.78%
- Median
- 0.00%
- Q1
- -4.14%
- Min
- -17.05%
Operating Margin (TTM)
Both Novartis (NVS) at 34.27% and BeOne Medicines (ONC) at 22.15% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
34.27%
- Max
- 83.12%
- NVS
- 34.27%
- Q3
- 14.77%
- Median
- 0.00%
- Q1
- -78.82%
- Min
- -207.40%
ONC
Pharmaceuticals, Biotechnology & Life Sciences industry group
22.15%
- Max
- 83.12%
- ONC
- 22.15%
- Q3
- 14.77%
- Median
- 0.00%
- Q1
- -78.82%
- Min
- -207.40%
Profitability Metrics
| Metric | NVS | ONC |
|---|---|---|
| ROE (TTM) | 24.33% | 18.40% |
| ROA (TTM) | 10.86% | 8.42% |
| Net Margin (TTM) | 17.49% | 13.86% |
| Operating Margin (TTM) | 34.27% | 22.15% |
| Gross Margin (TTM) | 75.21% | 89.39% |
Growth
Revenue Growth
Both Novartis (NVS) at 9.57% and BeOne Medicines (ONC) at 40.23% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.
EPS Growth
Only one side can be read here: Novartis (NVS) reports EPS growth of 21.81%, ranked against its industry; BeOne Medicines (ONC) has no EPS growth figure this period.
Growth Metrics
| Metric | NVS | ONC |
|---|---|---|
| Revenue Growth (YoY) | 9.57% | 40.23% |
| Revenue Growth (3Y CAGR) | 9.25% | 55.69% |
| EPS Growth (YoY) | 21.81% | -- |
| EPS Growth (3Y CAGR) | 31.14% | -- |
Financial Strength
Current Ratio (MRQ)
BeOne Medicines (ONC) at 3.55 keeps current ratio within its industry’s typical mid-range, while Novartis (NVS) at 0.88 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for NVS.
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.88
- Max
- 25.13
- Q3
- 12.13
- Median
- 5.52
- Q1
- 2.47
- NVS
- 0.88
- Min
- 0.10
ONC
Pharmaceuticals, Biotechnology & Life Sciences industry group
3.55
- Max
- 25.13
- Q3
- 12.13
- Median
- 5.52
- ONC
- 3.55
- Q1
- 2.47
- Min
- 0.10
Debt / Equity (MRQ)
BeOne Medicines (ONC) at 0.35 carries an industry-typical debt-to-equity mix, while Novartis (NVS) at 1.29 uses more debt funding than most peers.
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.29
- Max
- 1.42
- NVS
- 1.29
- Q3
- 0.65
- Median
- 0.15
- Q1
- 0.02
- Min
- 0.00
ONC
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.35
- Max
- 1.42
- Q3
- 0.65
- ONC
- 0.35
- Median
- 0.15
- Q1
- 0.02
- Min
- 0.00
Financial Strength Metrics
| Metric | NVS | ONC |
|---|---|---|
| Current Ratio (MRQ) | 0.88 | 3.55 |
| Debt / Equity (MRQ) | 1.29 | 0.35 |
| Net Debt / EBITDA | 1.64 | -2.80 |
Dividends
Dividend Yield (TTM)
BeOne Medicines (ONC) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Novartis (NVS) reports a yield of 2.88%, ranking against industry peers normally.
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
2.88%
- NVS
- 2.88%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
ONC
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.00%
- ONC
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Payout Ratio (TTM)
BeOne Medicines (ONC) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Novartis (NVS) reports a payout of 90.46%, ranking against industry peers normally.
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
90.46%
- NVS
- 90.46%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
ONC
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.00%
- ONC
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Metrics
| Metric | NVS | ONC |
|---|---|---|
| Dividend Yield (TTM) | 2.88% | 0.00% |
| Dividend Payout Ratio (TTM) | 90.46% | 0.00% |
Valuation
P/E Ratio (TTM)
Novartis (NVS) at 31.02 is near its industry’s usual P/E ratio, while BeOne Medicines (ONC) at 52.17 sits in the richer quartile — ONC needs stronger growth or earnings quality to justify the premium.
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
31.02
- Max
- 85.34
- Q3
- 43.46
- NVS
- 31.02
- Median
- 26.69
- Q1
- 13.30
- Min
- 0.07
ONC
Pharmaceuticals, Biotechnology & Life Sciences industry group
52.17
- Max
- 85.34
- ONC
- 52.17
- Q3
- 43.46
- Median
- 26.69
- Q1
- 13.30
- Min
- 0.07
P/S Ratio (TTM)
On P/S ratio, both Novartis (NVS) at 5.35 and BeOne Medicines (ONC) at 7.04 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
5.35
- Max
- 58.18
- Q3
- 25.77
- Median
- 7.30
- NVS
- 5.35
- Q1
- 3.01
- Min
- 0.01
ONC
Pharmaceuticals, Biotechnology & Life Sciences industry group
7.04
- Max
- 58.18
- Q3
- 25.77
- Median
- 7.30
- ONC
- 7.04
- Q1
- 3.01
- Min
- 0.01
P/B Ratio (MRQ)
Both Novartis (NVS) at 8.25 and BeOne Medicines (ONC) at 7.98 carry a premium to book value versus peers, sitting in the upper P/B ratio quartile of their industries.
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
8.25
- Max
- 13.53
- NVS
- 8.25
- Q3
- 6.54
- Median
- 3.25
- Q1
- 1.69
- Min
- -5.59
ONC
Pharmaceuticals, Biotechnology & Life Sciences industry group
7.98
- Max
- 13.53
- ONC
- 7.98
- Q3
- 6.54
- Median
- 3.25
- Q1
- 1.69
- Min
- -5.59
Valuation Metrics
| Metric | NVS | ONC |
|---|---|---|
| P/E Ratio (TTM) | 31.02 | 52.17 |
| P/S Ratio (TTM) | 5.35 | 7.04 |
| P/B Ratio (MRQ) | 8.25 | 7.98 |
| Free Cash Flow Yield (TTM) | 3.67% | 2.21% |