NTRA vs. NVO: Natera vs. Novo Nordisk Stock Comparison
How do Natera (NTRA) and Novo Nordisk (NVO) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.
Company Profile
Natera (NTRA) and Novo Nordisk (NVO) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but NTRA is classified in Biotechnology while NVO is classified in Pharmaceuticals.
Natera (NTRA) trades as ordinary local shares, while Novo Nordisk (NVO) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.
| Profile Item | NTRA | NVO |
|---|---|---|
| Name | Natera, Inc. | Novo Nordisk A/S Sponsored ADR |
| Country/Region | United States | Denmark |
| GICS Sector | Health Care | Health Care |
| GICS Industry Group | Pharmaceuticals, Biotechnology & Life Sciences | Pharmaceuticals, Biotechnology & Life Sciences |
| GICS Industry | Biotechnology | Pharmaceuticals |
| GICS Sub-Industry | Biotechnology | Pharmaceuticals |
| Market Capitalization | 45.05 billion USD | 177.74 billion USD |
| Currency | USD | USD |
| Exchange | Nasdaq | NYSE |
| Listing Date | July 1, 2015 | April 30, 1981 |
| Security Type | Common Stock | ADR |
Price Performance
Cumulative Growth
Trailing Returns
Calendar-Year Returns
Performance Metrics
| Metric | NTRA | NVO |
|---|---|---|
| Total Return (1Y) | 61.03% | -5.29% |
| Total Return (3Y, Annualized) | 92.02% | -23.41% |
| Total Return (5Y, Annualized) | 23.20% | -4.13% |
Risk Profile
Drawdown History
Return Distribution
Risk Metrics
Natera (NTRA) has an aggressive beta of 1.58, indicating higher sensitivity to broad-market moves, while Novo Nordisk (NVO) is defensive at 0.67 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.
| Metric | NTRA | NVO |
|---|---|---|
| Volatility (1Y, Annualized) | 52.30% | 45.98% |
| Beta (5Y) | 1.58 | 0.67 |
| Max Drawdown (5Y) | -75.72% | -74.70% |
| Avg. Volume (3M) | 1.68M | 12.11M |
Risk-Adjusted Performance
Risk-Return Positioning
Risk-Adjusted Metrics
| Metric | NTRA | NVO |
|---|---|---|
| Sharpe Ratio (1Y) | 1.09 | -0.21 |
| Sortino Ratio (1Y) | 1.63 | -0.28 |
Profitability
ROE (TTM)
Natera (NTRA) reports a negative ROE of -10.55%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile Novo Nordisk (NVO) reports 58.38%, ranking against industry peers normally.
NTRA
Pharmaceuticals, Biotechnology & Life Sciences industry group
-10.55%
- Max
- 109.18%
- Q3
- 6.23%
- NTRA
- -10.55%
- Median
- -26.66%
- Q1
- -64.05%
- Min
- -167.77%
NVO
Pharmaceuticals, Biotechnology & Life Sciences industry group
58.38%
- Max
- 109.18%
- NVO
- 58.38%
- Q3
- 6.23%
- Median
- -26.66%
- Q1
- -64.05%
- Min
- -167.77%
Net Margin (TTM)
Natera (NTRA) reports a negative net margin of -5.66%, usually indicating a net loss over the period. Meanwhile Novo Nordisk (NVO) reports 33.92%, ranking against industry peers normally.
NTRA
Pharmaceuticals, Biotechnology & Life Sciences industry group
-5.66%
- Max
- 18.05%
- Q3
- 4.78%
- Median
- 0.00%
- Q1
- -4.14%
- NTRA
- -5.66%
- Min
- -17.05%
NVO
Pharmaceuticals, Biotechnology & Life Sciences industry group
33.92%
- NVO
- 33.92%
- Max
- 18.05%
- Q3
- 4.78%
- Median
- 0.00%
- Q1
- -4.14%
- Min
- -17.05%
Operating Margin (TTM)
Natera (NTRA) reports a negative operating margin of -7.64%, usually indicating that operating costs exceeded revenue at the operating-income line. Meanwhile Novo Nordisk (NVO) reports 40.05%, ranking against industry peers normally.
NTRA
Pharmaceuticals, Biotechnology & Life Sciences industry group
-7.64%
- Max
- 83.12%
- Q3
- 14.77%
- Median
- 0.00%
- NTRA
- -7.64%
- Q1
- -78.82%
- Min
- -207.40%
NVO
Pharmaceuticals, Biotechnology & Life Sciences industry group
40.05%
- Max
- 83.12%
- NVO
- 40.05%
- Q3
- 14.77%
- Median
- 0.00%
- Q1
- -78.82%
- Min
- -207.40%
Profitability Metrics
| Metric | NTRA | NVO |
|---|---|---|
| ROE (TTM) | -10.55% | 58.38% |
| ROA (TTM) | -6.79% | 19.05% |
| Net Margin (TTM) | -5.66% | 33.92% |
| Operating Margin (TTM) | -7.64% | 40.05% |
| Gross Margin (TTM) | 65.14% | 83.33% |
Growth
Revenue Growth
Both Natera (NTRA) at 35.90% and Novo Nordisk (NVO) at 6.43% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.
EPS Growth
Only one side can be read here: Novo Nordisk (NVO) reports EPS growth of 1.77%, ranked against its industry; Natera (NTRA) has no EPS growth figure this period.
Growth Metrics
| Metric | NTRA | NVO |
|---|---|---|
| Revenue Growth (YoY) | 35.90% | 6.43% |
| Revenue Growth (3Y CAGR) | 41.14% | 20.43% |
| EPS Growth (YoY) | -- | 1.77% |
| EPS Growth (3Y CAGR) | -- | 23.52% |
Financial Strength
Current Ratio (MRQ)
Natera (NTRA) at 2.81 keeps current ratio within its industry’s typical mid-range, while Novo Nordisk (NVO) at 0.85 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for NVO.
NTRA
Pharmaceuticals, Biotechnology & Life Sciences industry group
2.81
- Max
- 25.13
- Q3
- 12.13
- Median
- 5.52
- NTRA
- 2.81
- Q1
- 2.47
- Min
- 0.10
NVO
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.85
- Max
- 25.13
- Q3
- 12.13
- Median
- 5.52
- Q1
- 2.47
- NVO
- 0.85
- Min
- 0.10
Debt / Equity (MRQ)
Both Natera (NTRA) at 0.13 and Novo Nordisk (NVO) at 0.62 fund their balance sheets with roughly industry-typical debt-to-equity mixes.
NTRA
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.13
- Max
- 1.42
- Q3
- 0.65
- Median
- 0.15
- NTRA
- 0.13
- Q1
- 0.02
- Min
- 0.00
NVO
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.62
- Max
- 1.42
- Q3
- 0.65
- NVO
- 0.62
- Median
- 0.15
- Q1
- 0.02
- Min
- 0.00
Financial Strength Metrics
| Metric | NTRA | NVO |
|---|---|---|
| Current Ratio (MRQ) | 2.81 | 0.85 |
| Debt / Equity (MRQ) | 0.13 | 0.62 |
| Net Debt / EBITDA | -- | 0.49 |
Dividends
Dividend Yield (TTM)
Natera (NTRA) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Novo Nordisk (NVO) reports a yield of 29.03%, ranking against industry peers normally.
NTRA
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.00%
- NTRA
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
NVO
Pharmaceuticals, Biotechnology & Life Sciences industry group
29.03%
- NVO
- 29.03%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Payout Ratio (TTM)
Natera (NTRA) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Novo Nordisk (NVO) reports a payout of 45.36%, ranking against industry peers normally.
NTRA
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.00%
- NTRA
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
NVO
Pharmaceuticals, Biotechnology & Life Sciences industry group
45.36%
- NVO
- 45.36%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Metrics
| Metric | NTRA | NVO |
|---|---|---|
| Dividend Yield (TTM) | 0.00% | 29.03% |
| Dividend Payout Ratio (TTM) | 0.00% | 45.36% |
Valuation
P/E Ratio (TTM)
An earnings multiple is available for just one side: Novo Nordisk (NVO) trades at 10.18 times trailing earnings, ranked against its peers, while Natera (NTRA) has no P/E ratio this period.
NTRA
Pharmaceuticals, Biotechnology & Life Sciences industry group
--
- Max
- 85.34
- Q3
- 43.46
- Median
- 26.69
- Q1
- 13.30
- Min
- 0.07
- NTRA
- --
NVO
Pharmaceuticals, Biotechnology & Life Sciences industry group
10.18
- Max
- 85.34
- Q3
- 43.46
- Median
- 26.69
- Q1
- 13.30
- NVO
- 10.18
- Min
- 0.07
P/S Ratio (TTM)
Novo Nordisk (NVO) at 0.53 sits in the cheaper P/S ratio quartile while Natera (NTRA) at 15.49 prices around its industry’s middle — NVO costs less per dollar of sales, though read it alongside growth and margins.
NTRA
Pharmaceuticals, Biotechnology & Life Sciences industry group
15.49
- Max
- 58.18
- Q3
- 25.77
- NTRA
- 15.49
- Median
- 7.30
- Q1
- 3.01
- Min
- 0.01
NVO
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.53
- Max
- 58.18
- Q3
- 25.77
- Median
- 7.30
- Q1
- 3.01
- NVO
- 0.53
- Min
- 0.01
P/B Ratio (MRQ)
Novo Nordisk (NVO) at 5.43 sits near its industry’s typical P/B ratio, while Natera (NTRA) at 23.99 prices above its benchmark range — NTRA looks rich relative to book.
NTRA
Pharmaceuticals, Biotechnology & Life Sciences industry group
23.99
- NTRA
- 23.99
- Max
- 13.53
- Q3
- 6.54
- Median
- 3.25
- Q1
- 1.69
- Min
- -5.59
NVO
Pharmaceuticals, Biotechnology & Life Sciences industry group
5.43
- Max
- 13.53
- Q3
- 6.54
- NVO
- 5.43
- Median
- 3.25
- Q1
- 1.69
- Min
- -5.59
Valuation Metrics
| Metric | NTRA | NVO |
|---|---|---|
| P/E Ratio (TTM) | -- | 10.18 |
| P/S Ratio (TTM) | 15.49 | 0.53 |
| P/B Ratio (MRQ) | 23.99 | 5.43 |
| Free Cash Flow Yield (TTM) | 0.19% | 18.43% |