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LLY vs. NTRA: Eli Lilly vs. Natera Stock Comparison

How do Eli Lilly (LLY) and Natera (NTRA) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Eli Lilly (LLY) and Natera (NTRA) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but LLY is classified in Pharmaceuticals while NTRA is classified in Biotechnology.

Company profile comparison for Eli Lilly (LLY) and Natera (NTRA)
Profile ItemLLYNTRA
NameEli Lilly and CompanyNatera, Inc.
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryPharmaceuticalsBiotechnology
GICS Sub-IndustryPharmaceuticalsBiotechnology
Market Capitalization1,206.07 billion USD45.05 billion USD
CurrencyUSDUSD
ExchangeNYSENasdaq
Listing DateJune 1, 1972July 1, 2015
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

LLY
NTRA
GSPC
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Eli Lilly (LLY) vs. Natera (NTRA), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Eli Lilly (LLY) and Natera (NTRA). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Eli Lilly (LLY) and Natera (NTRA). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Eli Lilly (LLY) and Natera (NTRA)
MetricLLYNTRA
Total Return (1Y)52.36%61.03%
Total Return (3Y, Annualized)34.18%92.02%
Total Return (5Y, Annualized)41.08%23.20%

Risk Profile

Drawdown History

LLY
NTRA
GSPC
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Eli Lilly (LLY) vs. Natera (NTRA), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Eli Lilly (LLY) and Natera (NTRA). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Natera (NTRA) has an aggressive beta of 1.58, indicating higher sensitivity to broad-market moves, while Eli Lilly (LLY) is defensive at 0.40 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.

Risk profile metrics for Eli Lilly (LLY) and Natera (NTRA)
MetricLLYNTRA
Volatility (1Y, Annualized)35.34%52.30%
Beta (5Y)0.401.58
Max Drawdown (5Y)-34.48%-75.72%
Avg. Volume (3M)2.52M1.68M

Risk-Adjusted Performance

Risk-Return Positioning

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LLY and NTRA are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Eli Lilly (LLY) and Natera (NTRA)
MetricLLYNTRA
Sharpe Ratio (1Y)1.361.09
Sortino Ratio (1Y)2.291.63

Profitability

ROE (TTM)

Natera (NTRA) reports a negative ROE of -10.55%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile Eli Lilly (LLY) reports 86.02%, ranking against industry peers normally.

LLY

Pharmaceuticals, Biotechnology & Life Sciences industry group

86.02%

Max
109.18%
LLY
86.02%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

-10.55%

Max
109.18%
Q3
6.23%
NTRA
-10.55%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Eli Lilly (LLY) vs. Natera (NTRA): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Natera (NTRA) reports a negative net margin of -5.66%, usually indicating a net loss over the period. Meanwhile Eli Lilly (LLY) reports 31.90%, ranking against industry peers normally.

LLY

Pharmaceuticals, Biotechnology & Life Sciences industry group

31.90%

LLY
31.90%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

-5.66%

Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
NTRA
-5.66%
Min
-17.05%
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Eli Lilly (LLY) vs. Natera (NTRA): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Natera (NTRA) reports a negative operating margin of -7.64%, usually indicating that operating costs exceeded revenue at the operating-income line. Meanwhile Eli Lilly (LLY) reports 53.66%, ranking against industry peers normally.

LLY

Pharmaceuticals, Biotechnology & Life Sciences industry group

53.66%

Max
83.12%
LLY
53.66%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

-7.64%

Max
83.12%
Q3
14.77%
Median
0.00%
NTRA
-7.64%
Q1
-78.82%
Min
-207.40%
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Eli Lilly (LLY) vs. Natera (NTRA): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Eli Lilly (LLY) and Natera (NTRA)
MetricLLYNTRA
ROE (TTM)86.02%-10.55%
ROA (TTM)21.06%-6.79%
Net Margin (TTM)31.90%-5.66%
Operating Margin (TTM)53.66%-7.64%
Gross Margin (TTM)83.63%65.14%

Growth

Revenue Growth

Both Eli Lilly (LLY) at 44.70% and Natera (NTRA) at 35.90% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

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Eli Lilly (LLY) vs. Natera (NTRA): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: Eli Lilly (LLY) reports EPS growth of 95.99%, ranked against its industry; Natera (NTRA) has no EPS growth figure this period.

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Eli Lilly (LLY) vs. Natera (NTRA): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Eli Lilly (LLY) and Natera (NTRA)
MetricLLYNTRA
Revenue Growth (YoY)44.70%35.90%
Revenue Growth (3Y CAGR)31.69%41.14%
EPS Growth (YoY)95.99%--
EPS Growth (3Y CAGR)51.71%--

Financial Strength

Current Ratio (MRQ)

Natera (NTRA) at 2.81 keeps current ratio within its industry’s typical mid-range, while Eli Lilly (LLY) at 1.39 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for LLY.

LLY

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.39

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
LLY
1.39
Min
0.10

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.81

Max
25.13
Q3
12.13
Median
5.52
NTRA
2.81
Q1
2.47
Min
0.10
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Eli Lilly (LLY) vs. Natera (NTRA): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Natera (NTRA) at 0.13 carries an industry-typical debt-to-equity mix, while Eli Lilly (LLY) at 1.23 uses more debt funding than most peers.

LLY

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.23

Max
1.42
LLY
1.23
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.13

Max
1.42
Q3
0.65
Median
0.15
NTRA
0.13
Q1
0.02
Min
0.00
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Eli Lilly (LLY) vs. Natera (NTRA): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Eli Lilly (LLY) and Natera (NTRA)
MetricLLYNTRA
Current Ratio (MRQ)1.392.81
Debt / Equity (MRQ)1.230.13
Net Debt / EBITDA0.96--

Dividends

Dividend Yield (TTM)

Natera (NTRA) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Eli Lilly (LLY) reports a yield of 0.49%, ranking against industry peers normally.

LLY

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.49%

LLY
0.49%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

NTRA
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Eli Lilly (LLY) vs. Natera (NTRA): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Natera (NTRA) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Eli Lilly (LLY) reports a payout of 21.71%, ranking against industry peers normally.

LLY

Pharmaceuticals, Biotechnology & Life Sciences industry group

21.71%

LLY
21.71%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

NTRA
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Eli Lilly (LLY) vs. Natera (NTRA): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Eli Lilly (LLY) and Natera (NTRA)
MetricLLYNTRA
Dividend Yield (TTM)0.49%0.00%
Dividend Payout Ratio (TTM)21.71%0.00%

Valuation

P/E Ratio (TTM)

An earnings multiple is available for just one side: Eli Lilly (LLY) trades at 43.95 times trailing earnings, ranked against its peers, while Natera (NTRA) has no P/E ratio this period.

LLY

Pharmaceuticals, Biotechnology & Life Sciences industry group

43.95

Max
85.34
LLY
43.95
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
NTRA
--
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Eli Lilly (LLY) vs. Natera (NTRA): NTRA does not report P/E ratio, so it has no value marker; LLY is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

P/S Ratio (TTM)

On P/S ratio, both Eli Lilly (LLY) at 13.95 and Natera (NTRA) at 15.49 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

LLY

Pharmaceuticals, Biotechnology & Life Sciences industry group

13.95

Max
58.18
Q3
25.77
LLY
13.95
Median
7.30
Q1
3.01
Min
0.01

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

15.49

Max
58.18
Q3
25.77
NTRA
15.49
Median
7.30
Q1
3.01
Min
0.01
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Eli Lilly (LLY) vs. Natera (NTRA): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Measured against book value, both Eli Lilly (LLY) at 29.96 and Natera (NTRA) at 23.99 look expensive — each P/B ratio sits above its industry’s benchmark range.

LLY

Pharmaceuticals, Biotechnology & Life Sciences industry group

29.96

LLY
29.96
Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

23.99

NTRA
23.99
Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
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Eli Lilly (LLY) vs. Natera (NTRA): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Eli Lilly (LLY) and Natera (NTRA)
MetricLLYNTRA
P/E Ratio (TTM)43.95--
P/S Ratio (TTM)13.9515.49
P/B Ratio (MRQ)29.9623.99
Free Cash Flow Yield (TTM)0.77%0.19%