LLY vs. NVO: Eli Lilly vs. Novo Nordisk Stock Comparison
How do Eli Lilly (LLY) and Novo Nordisk (NVO) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.
Company Profile
Eli Lilly (LLY) and Novo Nordisk (NVO) are both classified in the Pharmaceuticals sub-industry within the broader Pharmaceuticals industry, placing them in the closest GICS peer bucket.
Eli Lilly (LLY) trades as ordinary local shares, while Novo Nordisk (NVO) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.
| Profile Item | LLY | NVO |
|---|---|---|
| Name | Eli Lilly and Company | Novo Nordisk A/S Sponsored ADR |
| Country/Region | United States | Denmark |
| GICS Sector | Health Care | Health Care |
| GICS Industry Group | Pharmaceuticals, Biotechnology & Life Sciences | Pharmaceuticals, Biotechnology & Life Sciences |
| GICS Industry | Pharmaceuticals | Pharmaceuticals |
| GICS Sub-Industry | Pharmaceuticals | Pharmaceuticals |
| Market Capitalization | 1,048.16 billion USD | 218.40 billion USD |
| Currency | USD | USD |
| Exchange | NYSE | NYSE |
| Listing Date | June 1, 1972 | April 30, 1981 |
| Security Type | Common Stock | ADR |
Price Performance
Cumulative Growth
Trailing Returns
Calendar-Year Returns
Performance Metrics
| Metric | LLY | NVO |
|---|---|---|
| Total Return (1Y) | 55.31% | -20.26% |
| Total Return (3Y, Annualized) | 37.48% | -13.59% |
| Total Return (5Y, Annualized) | 39.02% | 4.36% |
Risk Profile
Drawdown History
Return Distribution
Risk Metrics
| Metric | LLY | NVO |
|---|---|---|
| Volatility (1Y, Annualized) | 38.62% | 51.79% |
| Beta (5Y) | 0.51 | 0.75 |
| Max Drawdown (5Y) | -34.48% | -74.70% |
| Avg. Volume (3M) | 3.24M | 13.81M |
Risk-Adjusted Performance
Risk-Return Positioning
Risk-Adjusted Metrics
| Metric | LLY | NVO |
|---|---|---|
| Sharpe Ratio (1Y) | 1.33 | -0.47 |
| Sortino Ratio (1Y) | 2.04 | -0.61 |
Profitability
ROE (TTM)
Both companies show strong equity returns, but Eli Lilly (LLY) at 107.46% is the standout with ROE above its industry range; Novo Nordisk (NVO) at 71.40% also sits in the top quartile.
LLY
Pharmaceuticals, Biotechnology & Life Sciences industry group
107.46%
- LLY
- 107.46%
- Max
- 99.40%
- Q3
- 2.50%
- Median
- -31.42%
- Q1
- -62.21%
- Min
- -157.07%
NVO
Pharmaceuticals, Biotechnology & Life Sciences industry group
71.40%
- Max
- 99.40%
- NVO
- 71.40%
- Q3
- 2.50%
- Median
- -31.42%
- Q1
- -62.21%
- Min
- -157.07%
Net Margin (TTM)
Both Eli Lilly (LLY) at 34.99% and Novo Nordisk (NVO) at 37.21% keep an unusually large share of revenue as bottom-line profit — each net margin clears its industry’s benchmark range.
LLY
Pharmaceuticals, Biotechnology & Life Sciences industry group
34.99%
- LLY
- 34.99%
- Max
- 11.75%
- Q3
- 2.69%
- Median
- 0.00%
- Q1
- -3.38%
- Min
- -11.53%
NVO
Pharmaceuticals, Biotechnology & Life Sciences industry group
37.21%
- NVO
- 37.21%
- Max
- 11.75%
- Q3
- 2.69%
- Median
- 0.00%
- Q1
- -3.38%
- Min
- -11.53%
Operating Margin (TTM)
Both Eli Lilly (LLY) at 49.39% and Novo Nordisk (NVO) at 61.57% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.
LLY
Pharmaceuticals, Biotechnology & Life Sciences industry group
49.39%
- Max
- 100.30%
- LLY
- 49.39%
- Q3
- 4.66%
- Median
- 0.00%
- Q1
- -121.08%
- Min
- -309.54%
NVO
Pharmaceuticals, Biotechnology & Life Sciences industry group
61.57%
- Max
- 100.30%
- NVO
- 61.57%
- Q3
- 4.66%
- Median
- 0.00%
- Q1
- -121.08%
- Min
- -309.54%
Profitability Metrics
| Metric | LLY | NVO |
|---|---|---|
| ROE (TTM) | 107.46% | 71.40% |
| ROA (TTM) | 20.74% | 19.25% |
| Net Margin (TTM) | 34.99% | 37.21% |
| Operating Margin (TTM) | 49.39% | 61.57% |
| Gross Margin (TTM) | 82.83% | 83.20% |
Growth
Revenue Growth
Both Eli Lilly (LLY) at 44.70% and Novo Nordisk (NVO) at 6.43% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.
EPS Growth
Eli Lilly (LLY) at 95.99% sits in the top EPS growth quartile, while Novo Nordisk (NVO) at 1.77% is closer to the peer norm — faster per-share earnings growth for LLY.
Growth Metrics
| Metric | LLY | NVO |
|---|---|---|
| Revenue Growth (YoY) | 44.70% | 6.43% |
| Revenue Growth (3Y CAGR) | 31.69% | 20.43% |
| EPS Growth (YoY) | 95.99% | 1.77% |
| EPS Growth (3Y CAGR) | 51.71% | 23.52% |
Financial Strength
Current Ratio (MRQ)
Both Eli Lilly (LLY) at 1.50 and Novo Nordisk (NVO) at 0.79 run current ratio in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.
LLY
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.50
- Max
- 26.16
- Q3
- 12.33
- Median
- 5.81
- Q1
- 2.71
- LLY
- 1.50
- Min
- 0.28
NVO
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.79
- Max
- 26.16
- Q3
- 12.33
- Median
- 5.81
- Q1
- 2.71
- NVO
- 0.79
- Min
- 0.28
Debt / Equity (MRQ)
Both Eli Lilly (LLY) at 1.39 and Novo Nordisk (NVO) at 0.72 lean more heavily on debt funding than most peers, landing in the higher-leverage quartile of their industries.
LLY
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.39
- Max
- 1.60
- LLY
- 1.39
- Q3
- 0.68
- Median
- 0.15
- Q1
- 0.02
- Min
- 0.00
NVO
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.72
- Max
- 1.60
- NVO
- 0.72
- Q3
- 0.68
- Median
- 0.15
- Q1
- 0.02
- Min
- 0.00
Financial Strength Metrics
| Metric | LLY | NVO |
|---|---|---|
| Current Ratio (MRQ) | 1.50 | 0.79 |
| Debt / Equity (MRQ) | 1.39 | 0.72 |
| Net Debt / EBITDA | 1.05 | 0.72 |
Dividends
Dividend Yield (TTM)
Both Eli Lilly (LLY) at 0.54% and Novo Nordisk (NVO) at 23.58% yield above their industries’ entire benchmark ranges — high enough that dividend safety, not income, becomes the first question.
LLY
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.54%
- LLY
- 0.54%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
NVO
Pharmaceuticals, Biotechnology & Life Sciences industry group
23.58%
- NVO
- 23.58%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Payout Ratio (TTM)
Both Eli Lilly (LLY) at 22.13% and Novo Nordisk (NVO) at 42.59% pay out more of their earnings than any of their industry peers — the thinnest cover in their groups, so dividend headroom deserves attention.
LLY
Pharmaceuticals, Biotechnology & Life Sciences industry group
22.13%
- LLY
- 22.13%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
NVO
Pharmaceuticals, Biotechnology & Life Sciences industry group
42.59%
- NVO
- 42.59%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Metrics
| Metric | LLY | NVO |
|---|---|---|
| Dividend Yield (TTM) | 0.54% | 23.58% |
| Dividend Payout Ratio (TTM) | 22.13% | 42.59% |
Valuation
P/E Ratio (TTM)
Novo Nordisk (NVO) at 11.90 sits in the cheaper P/E ratio quartile, while Eli Lilly (LLY) at 40.81 is closer to its industry’s usual earnings multiple — a discount for NVO, though growth and earnings durability still matter.
LLY
Pharmaceuticals, Biotechnology & Life Sciences industry group
40.81
- Max
- 79.93
- Q3
- 47.39
- LLY
- 40.81
- Median
- 25.31
- Q1
- 15.26
- Min
- 2.05
NVO
Pharmaceuticals, Biotechnology & Life Sciences industry group
11.90
- Max
- 79.93
- Q3
- 47.39
- Median
- 25.31
- Q1
- 15.26
- NVO
- 11.90
- Min
- 2.05
P/S Ratio (TTM)
Novo Nordisk (NVO) at 0.67 sits in the cheaper P/S ratio quartile while Eli Lilly (LLY) at 14.51 prices around its industry’s middle — NVO costs less per dollar of sales, though read it alongside growth and margins.
LLY
Pharmaceuticals, Biotechnology & Life Sciences industry group
14.51
- Max
- 63.16
- Q3
- 28.29
- LLY
- 14.51
- Median
- 8.07
- Q1
- 3.52
- Min
- 0.01
NVO
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.67
- Max
- 63.16
- Q3
- 28.29
- Median
- 8.07
- Q1
- 3.52
- NVO
- 0.67
- Min
- 0.01
P/B Ratio (MRQ)
Novo Nordisk (NVO) at 7.08 sits near its industry’s typical P/B ratio, while Eli Lilly (LLY) at 33.66 prices above its benchmark range — LLY looks rich relative to book.
LLY
Pharmaceuticals, Biotechnology & Life Sciences industry group
33.66
- LLY
- 33.66
- Max
- 16.09
- Q3
- 7.48
- Median
- 3.80
- Q1
- 1.72
- Min
- -5.70
NVO
Pharmaceuticals, Biotechnology & Life Sciences industry group
7.08
- Max
- 16.09
- Q3
- 7.48
- NVO
- 7.08
- Median
- 3.80
- Q1
- 1.72
- Min
- -5.70
Valuation Metrics
| Metric | LLY | NVO |
|---|---|---|
| P/E Ratio (TTM) | 40.81 | 11.90 |
| P/S Ratio (TTM) | 14.51 | 0.67 |
| P/B Ratio (MRQ) | 33.66 | 7.08 |
| Free Cash Flow Yield (TTM) | 0.87% | -5.51% |