KYMR vs. NVS: Kymera Therapeutics vs. Novartis Stock Comparison
How do Kymera Therapeutics (KYMR) and Novartis (NVS) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.
Company Profile
Kymera Therapeutics (KYMR) and Novartis (NVS) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but KYMR is classified in Biotechnology while NVS is classified in Pharmaceuticals.
Novartis (NVS) has more than two decades of public-market history since November 7, 1996, whereas Kymera Therapeutics (KYMR) listed on August 21, 2020 and has a much shorter record to draw on.
Kymera Therapeutics (KYMR) trades as ordinary local shares, while Novartis (NVS) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.
| Profile Item | KYMR | NVS |
|---|---|---|
| Name | Kymera Therapeutics Inc. | Novartis AG Sponsored ADR |
| Country/Region | United States | Switzerland |
| GICS Sector | Health Care | Health Care |
| GICS Industry Group | Pharmaceuticals, Biotechnology & Life Sciences | Pharmaceuticals, Biotechnology & Life Sciences |
| GICS Industry | Biotechnology | Pharmaceuticals |
| GICS Sub-Industry | Biotechnology | Pharmaceuticals |
| Market Capitalization | 11.25 billion USD | 307.00 billion USD |
| Currency | USD | USD |
| Exchange | Nasdaq | NYSE |
| Listing Date | August 21, 2020 | November 7, 1996 |
| Security Type | Common Stock | ADR |
Price Performance
Cumulative Growth
Trailing Returns
Calendar-Year Returns
Performance Metrics
| Metric | KYMR | NVS |
|---|---|---|
| Total Return (1Y) | 131.52% | 32.98% |
| Total Return (3Y, Annualized) | 111.65% | 24.72% |
| Total Return (5Y, Annualized) | 15.68% | 18.80% |
Risk Profile
Drawdown History
Return Distribution
Risk Metrics
Kymera Therapeutics (KYMR) has an aggressive beta of 2.00, indicating higher sensitivity to broad-market moves, while Novartis (NVS) is defensive at 0.41 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.
| Metric | KYMR | NVS |
|---|---|---|
| Volatility (1Y, Annualized) | 62.83% | 27.12% |
| Beta (5Y) | 2.00 | 0.41 |
| Max Drawdown (5Y) | -83.27% | -20.42% |
| Avg. Volume (3M) | 833.05K | 2.07M |
Risk-Adjusted Performance
Risk-Return Positioning
Risk-Adjusted Metrics
| Metric | KYMR | NVS |
|---|---|---|
| Sharpe Ratio (1Y) | 2.03 | 1.06 |
| Sortino Ratio (1Y) | 4.16 | 1.46 |
Profitability
ROE (TTM)
Kymera Therapeutics (KYMR) reports a negative ROE of -27.29%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile Novartis (NVS) reports 24.33%, ranking against industry peers normally.
KYMR
Pharmaceuticals, Biotechnology & Life Sciences industry group
-27.29%
- Max
- 109.18%
- Q3
- 6.23%
- Median
- -26.66%
- KYMR
- -27.29%
- Q1
- -64.05%
- Min
- -167.77%
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
24.33%
- Max
- 109.18%
- NVS
- 24.33%
- Q3
- 6.23%
- Median
- -26.66%
- Q1
- -64.05%
- Min
- -167.77%
Net Margin (TTM)
Novartis (NVS) at 17.49% retains a top-quartile share of revenue as profit, ahead of Kymera Therapeutics (KYMR) at 0.00%, which keeps about the industry-typical share.
KYMR
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.00%
- Max
- 18.05%
- Q3
- 4.78%
- KYMR
- 0.00%
- Median
- 0.00%
- Q1
- -4.14%
- Min
- -17.05%
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
17.49%
- Max
- 18.05%
- NVS
- 17.49%
- Q3
- 4.78%
- Median
- 0.00%
- Q1
- -4.14%
- Min
- -17.05%
Operating Margin (TTM)
Kymera Therapeutics (KYMR) reports a negative operating margin of -396.04%, usually indicating that operating costs exceeded revenue at the operating-income line. Meanwhile Novartis (NVS) reports 34.27%, ranking against industry peers normally.
KYMR
Pharmaceuticals, Biotechnology & Life Sciences industry group
-396.04%
- Max
- 83.12%
- Q3
- 14.77%
- Median
- 0.00%
- Q1
- -78.82%
- Min
- -207.40%
- KYMR
- -396.04%
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
34.27%
- Max
- 83.12%
- NVS
- 34.27%
- Q3
- 14.77%
- Median
- 0.00%
- Q1
- -78.82%
- Min
- -207.40%
Profitability Metrics
| Metric | KYMR | NVS |
|---|---|---|
| ROE (TTM) | -27.29% | 24.33% |
| ROA (TTM) | -17.64% | 10.86% |
| Net Margin (TTM) | 0.00% | 17.49% |
| Operating Margin (TTM) | -396.04% | 34.27% |
| Gross Margin (TTM) | 0.00% | 75.21% |
Growth
Revenue Growth
Novartis (NVS) at 9.57% is around its peer norm for revenue growth, while Kymera Therapeutics (KYMR) at -16.70% drops into the bottom quartile, signaling weaker demand or pricing momentum.
EPS Growth
Only one side can be read here: Novartis (NVS) reports EPS growth of 21.81%, ranked against its industry; Kymera Therapeutics (KYMR) has no EPS growth figure this period.
Growth Metrics
| Metric | KYMR | NVS |
|---|---|---|
| Revenue Growth (YoY) | -16.70% | 9.57% |
| Revenue Growth (3Y CAGR) | -5.74% | 9.25% |
| EPS Growth (YoY) | -- | 21.81% |
| EPS Growth (3Y CAGR) | -- | 31.14% |
Financial Strength
Current Ratio (MRQ)
Kymera Therapeutics (KYMR) at 11.13 keeps current ratio within its industry’s typical mid-range, while Novartis (NVS) at 0.88 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for NVS.
KYMR
Pharmaceuticals, Biotechnology & Life Sciences industry group
11.13
- Max
- 25.13
- Q3
- 12.13
- KYMR
- 11.13
- Median
- 5.52
- Q1
- 2.47
- Min
- 0.10
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.88
- Max
- 25.13
- Q3
- 12.13
- Median
- 5.52
- Q1
- 2.47
- NVS
- 0.88
- Min
- 0.10
Debt / Equity (MRQ)
Kymera Therapeutics (KYMR) at 0.05 carries an industry-typical debt-to-equity mix, while Novartis (NVS) at 1.29 uses more debt funding than most peers.
KYMR
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.05
- Max
- 1.42
- Q3
- 0.65
- Median
- 0.15
- KYMR
- 0.05
- Q1
- 0.02
- Min
- 0.00
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.29
- Max
- 1.42
- NVS
- 1.29
- Q3
- 0.65
- Median
- 0.15
- Q1
- 0.02
- Min
- 0.00
Financial Strength Metrics
| Metric | KYMR | NVS |
|---|---|---|
| Current Ratio (MRQ) | 11.13 | 0.88 |
| Debt / Equity (MRQ) | 0.05 | 1.29 |
| Net Debt / EBITDA | -- | 1.64 |
Dividends
Dividend Yield (TTM)
Kymera Therapeutics (KYMR) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Novartis (NVS) reports a yield of 2.88%, ranking against industry peers normally.
KYMR
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.00%
- KYMR
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
2.88%
- NVS
- 2.88%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Payout Ratio (TTM)
Kymera Therapeutics (KYMR) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Novartis (NVS) reports a payout of 90.46%, ranking against industry peers normally.
KYMR
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.00%
- KYMR
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
90.46%
- NVS
- 90.46%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Metrics
| Metric | KYMR | NVS |
|---|---|---|
| Dividend Yield (TTM) | 0.00% | 2.88% |
| Dividend Payout Ratio (TTM) | 0.00% | 90.46% |
Valuation
P/E Ratio (TTM)
An earnings multiple is available for just one side: Novartis (NVS) trades at 31.02 times trailing earnings, ranked against its peers, while Kymera Therapeutics (KYMR) has no P/E ratio this period.
KYMR
Pharmaceuticals, Biotechnology & Life Sciences industry group
--
- Max
- 85.34
- Q3
- 43.46
- Median
- 26.69
- Q1
- 13.30
- Min
- 0.07
- KYMR
- --
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
31.02
- Max
- 85.34
- Q3
- 43.46
- NVS
- 31.02
- Median
- 26.69
- Q1
- 13.30
- Min
- 0.07
P/S Ratio (TTM)
Novartis (NVS) at 5.35 prices around its industry’s typical P/S ratio, while Kymera Therapeutics (KYMR) at 110.00 clears its benchmark range — KYMR looks notably rich on sales.
KYMR
Pharmaceuticals, Biotechnology & Life Sciences industry group
110.00
- KYMR
- 110.00
- Max
- 58.18
- Q3
- 25.77
- Median
- 7.30
- Q1
- 3.01
- Min
- 0.01
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
5.35
- Max
- 58.18
- Q3
- 25.77
- Median
- 7.30
- NVS
- 5.35
- Q1
- 3.01
- Min
- 0.01
P/B Ratio (MRQ)
Both Kymera Therapeutics (KYMR) at 6.96 and Novartis (NVS) at 8.25 carry a premium to book value versus peers, sitting in the upper P/B ratio quartile of their industries.
KYMR
Pharmaceuticals, Biotechnology & Life Sciences industry group
6.96
- Max
- 13.53
- KYMR
- 6.96
- Q3
- 6.54
- Median
- 3.25
- Q1
- 1.69
- Min
- -5.59
NVS
Pharmaceuticals, Biotechnology & Life Sciences industry group
8.25
- Max
- 13.53
- NVS
- 8.25
- Q3
- 6.54
- Median
- 3.25
- Q1
- 1.69
- Min
- -5.59
Valuation Metrics
| Metric | KYMR | NVS |
|---|---|---|
| P/E Ratio (TTM) | -- | 31.02 |
| P/S Ratio (TTM) | 110.00 | 5.35 |
| P/B Ratio (MRQ) | 6.96 | 8.25 |
| Free Cash Flow Yield (TTM) | -1.46% | 3.67% |