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TEM vs. ZTS: Tempus AI vs. Zoetis Stock Comparison

How do Tempus AI (TEM) and Zoetis (ZTS) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Tempus AI (TEM) and Zoetis (ZTS) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but TEM is classified in Life Sciences Tools & Services while ZTS is classified in Pharmaceuticals.

Zoetis (ZTS) has been public since February 1, 2013, giving it a longer listed trading history, while Tempus AI (TEM) listed on June 14, 2024 and still has a shorter public-market record.

Company profile comparison for Tempus AI (TEM) and Zoetis (ZTS)
Profile ItemTEMZTS
NameTempus AI Inc Class A Common StockZoetis Inc. Class A Common Stock
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryLife Sciences Tools & ServicesPharmaceuticals
GICS Sub-IndustryLife Sciences Tools & ServicesPharmaceuticals
Market Capitalization13.87 billion USD32.26 billion USD
CurrencyUSDUSD
ExchangeNasdaqNYSE
Listing DateJune 14, 2024February 1, 2013
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

TEM
ZTS
GSPC
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Tempus AI (TEM) vs. Zoetis (ZTS), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Tempus AI (TEM) and Zoetis (ZTS). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Tempus AI (TEM) and Zoetis (ZTS). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Tempus AI (TEM) and Zoetis (ZTS)
MetricTEMZTS
Total Return (1Y)16.25%-30.10%
Total Return (3Y, Annualized)---20.42%
Total Return (5Y, Annualized)---16.87%

Risk Profile

Drawdown History

TEM
ZTS
GSPC
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Tempus AI (TEM) vs. Zoetis (ZTS), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Tempus AI (TEM) and Zoetis (ZTS). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Tempus AI (TEM) has a highly aggressive beta of 3.34, indicating much higher sensitivity to broad-market moves, while Zoetis (ZTS) is defensive at 0.66 and tends to be less market-sensitive — a wide gap in beta profiles.

Risk profile metrics for Tempus AI (TEM) and Zoetis (ZTS)
MetricTEMZTS
Volatility (1Y, Annualized)76.08%38.23%
Beta (5Y)3.340.66
Max Drawdown (5Y)-59.76%-70.45%
Avg. Volume (3M)7.20M4.65M

Risk-Adjusted Performance

Risk-Return Positioning

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TEM and ZTS are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Tempus AI (TEM) and Zoetis (ZTS)
MetricTEMZTS
Sharpe Ratio (1Y)0.16-0.90
Sortino Ratio (1Y)0.26-1.10

Profitability

ROE (TTM)

Tempus AI (TEM) reports a negative ROE of -37.55%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile Zoetis (ZTS) reports 57.63%, ranking against industry peers normally.

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

-37.55%

Max
109.18%
Q3
6.23%
Median
-26.66%
TEM
-37.55%
Q1
-64.05%
Min
-167.77%

ZTS

Pharmaceuticals, Biotechnology & Life Sciences industry group

57.63%

Max
109.18%
ZTS
57.63%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Tempus AI (TEM) vs. Zoetis (ZTS): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Tempus AI (TEM) reports a negative net margin of -12.54%, usually indicating a net loss over the period. Meanwhile Zoetis (ZTS) reports 26.41%, ranking against industry peers normally.

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

-12.54%

Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
TEM
-12.54%
Min
-17.05%

ZTS

Pharmaceuticals, Biotechnology & Life Sciences industry group

26.41%

ZTS
26.41%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Tempus AI (TEM) vs. Zoetis (ZTS): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Tempus AI (TEM) reports a negative operating margin of -13.82%, usually indicating that operating costs exceeded revenue at the operating-income line. Meanwhile Zoetis (ZTS) reports 38.19%, ranking against industry peers normally.

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

-13.82%

Max
83.12%
Q3
14.77%
Median
0.00%
TEM
-13.82%
Q1
-78.82%
Min
-207.40%

ZTS

Pharmaceuticals, Biotechnology & Life Sciences industry group

38.19%

Max
83.12%
ZTS
38.19%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Tempus AI (TEM) vs. Zoetis (ZTS): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Tempus AI (TEM) and Zoetis (ZTS)
MetricTEMZTS
ROE (TTM)-37.55%57.63%
ROA (TTM)-7.36%14.87%
Net Margin (TTM)-12.54%26.41%
Operating Margin (TTM)-13.82%38.19%
Gross Margin (TTM)64.46%71.65%

Growth

Revenue Growth

Tempus AI (TEM) at 83.41% sits in the top revenue growth quartile, while Zoetis (ZTS) at 2.28% is closer to the peer norm — faster top-line expansion for TEM.

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Tempus AI (TEM) vs. Zoetis (ZTS): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: Zoetis (ZTS) reports EPS growth of 10.05%, ranked against its industry; Tempus AI (TEM) has no EPS growth figure this period.

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Tempus AI (TEM) vs. Zoetis (ZTS): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Tempus AI (TEM) and Zoetis (ZTS)
MetricTEMZTS
Revenue Growth (YoY)83.41%2.28%
Revenue Growth (3Y CAGR)58.29%5.42%
EPS Growth (YoY)--10.05%
EPS Growth (3Y CAGR)--10.27%

Financial Strength

Current Ratio (MRQ)

Tempus AI (TEM) at 2.61 keeps current ratio within its industry’s typical mid-range, while Zoetis (ZTS) at 2.35 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for ZTS.

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.61

Max
25.13
Q3
12.13
Median
5.52
TEM
2.61
Q1
2.47
Min
0.10

ZTS

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.35

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
ZTS
2.35
Min
0.10
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Tempus AI (TEM) vs. Zoetis (ZTS): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Debt sits unusually high against shareholders’ equity for both Tempus AI (TEM) at 2.86 and Zoetis (ZTS) at 2.80 — each debt-to-equity ratio is above its industry benchmark range.

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.86

TEM
2.86
Max
1.42
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

ZTS

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.80

ZTS
2.80
Max
1.42
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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Tempus AI (TEM) vs. Zoetis (ZTS): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Tempus AI (TEM) and Zoetis (ZTS)
MetricTEMZTS
Current Ratio (MRQ)2.612.35
Debt / Equity (MRQ)2.862.80
Net Debt / EBITDA--1.92

Dividends

Dividend Yield (TTM)

Tempus AI (TEM) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Zoetis (ZTS) reports a yield of 2.55%, ranking against industry peers normally.

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

TEM
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

ZTS

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.55%

ZTS
2.55%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Tempus AI (TEM) vs. Zoetis (ZTS): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Tempus AI (TEM) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Zoetis (ZTS) reports a payout of 35.24%, ranking against industry peers normally.

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

TEM
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

ZTS

Pharmaceuticals, Biotechnology & Life Sciences industry group

35.24%

ZTS
35.24%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Tempus AI (TEM) vs. Zoetis (ZTS): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Tempus AI (TEM) and Zoetis (ZTS)
MetricTEMZTS
Dividend Yield (TTM)0.00%2.55%
Dividend Payout Ratio (TTM)0.00%35.24%

Valuation

P/E Ratio (TTM)

An earnings multiple is available for just one side: Zoetis (ZTS) trades at 13.50 times trailing earnings, ranked against its peers, while Tempus AI (TEM) has no P/E ratio this period.

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
TEM
--

ZTS

Pharmaceuticals, Biotechnology & Life Sciences industry group

13.50

Max
85.34
Q3
43.46
Median
26.69
ZTS
13.50
Q1
13.30
Min
0.07
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Tempus AI (TEM) vs. Zoetis (ZTS): TEM does not report P/E ratio, so it has no value marker; ZTS is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

P/S Ratio (TTM)

On P/S ratio, both Tempus AI (TEM) at 9.19 and Zoetis (ZTS) at 3.40 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

9.19

Max
58.18
Q3
25.77
TEM
9.19
Median
7.30
Q1
3.01
Min
0.01

ZTS

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.40

Max
58.18
Q3
25.77
Median
7.30
ZTS
3.40
Q1
3.01
Min
0.01
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Tempus AI (TEM) vs. Zoetis (ZTS): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Both look rich against book: Zoetis (ZTS) at 9.80 sits in the upper P/B ratio quartile, and Tempus AI (TEM) at 27.66 prices even higher, above its industry range.

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

27.66

TEM
27.66
Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

ZTS

Pharmaceuticals, Biotechnology & Life Sciences industry group

9.80

Max
13.53
ZTS
9.80
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
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Tempus AI (TEM) vs. Zoetis (ZTS): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Tempus AI (TEM) and Zoetis (ZTS)
MetricTEMZTS
P/E Ratio (TTM)--13.50
P/S Ratio (TTM)9.193.40
P/B Ratio (MRQ)27.669.80
Free Cash Flow Yield (TTM)0.30%6.36%