PEN vs. SYK: Penumbra vs. Stryker Stock Comparison

November 11, 2026

How do Penumbra (PEN) and Stryker (SYK) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Penumbra (PEN) and Stryker (SYK) are both classified in the Health Care Equipment sub-industry within the broader Health Care Equipment & Supplies industry, placing them in the closest GICS peer bucket.

Company profile comparison for Penumbra (PEN) and Stryker (SYK)
Profile Item	PEN	SYK
Name	Penumbra Inc.	Stryker Corp.
Country/Region	United States	United States
GICS Sector	Health Care	Health Care
GICS Industry Group	Health Care Equipment & Services	Health Care Equipment & Services
GICS Industry	Health Care Equipment & Supplies	Health Care Equipment & Supplies
GICS Sub-Industry	Health Care Equipment	Health Care Equipment
Market Capitalization	12.58 billion USD	124.06 billion USD
Currency	USD	USD
Exchange	NYSE	NYSE
Listing Date	September 18, 2015	March 17, 1980
Security Type	Common Stock	Common Stock

Price Performance

Cumulative Growth

PEN

SYK

GSPC

Penumbra (PEN) vs. Stryker (SYK), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Penumbra (PEN) and Stryker (SYK). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Penumbra (PEN) and Stryker (SYK). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Penumbra (PEN) and Stryker (SYK)
Metric	PEN	SYK
Total Return (1Y)	20.52%	-6.99%
Total Return (3Y, Annualized)	20.38%	7.60%
Total Return (5Y, Annualized)	3.15%	4.64%

Risk Profile

Drawdown History

PEN

SYK

GSPC

Penumbra (PEN) vs. Stryker (SYK), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Penumbra (PEN) and Stryker (SYK). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Penumbra (PEN) and Stryker (SYK)
Metric	PEN	SYK
Volatility (1Y, Annualized)	19.78%	32.80%
Beta (5Y)	0.68	0.72
Max Drawdown (5Y)	-59.60%	-32.47%
Avg. Volume (3M)	348.64K	2.81M

Risk-Adjusted Performance

Risk-Return Positioning

PEN and SYK are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Penumbra (PEN) and Stryker (SYK)
Metric	PEN	SYK
Sharpe Ratio (1Y)	0.82	-0.34
Sortino Ratio (1Y)	1.56	-0.49

Profitability

ROE (TTM)

Stryker (SYK) at 16.02% sits in the top ROE quartile, while Penumbra (PEN) at 10.67% is closer to the peer norm — stronger capital efficiency for SYK.

PEN

Health Care Equipment & Services industry group

10.67%

Max: 47.61%
Q3: 14.36%
PEN: 10.67%
Median: 5.45%
Q1: -10.67%
Min: -47.01%

SYK

Health Care Equipment & Services industry group

16.02%

Max: 47.61%
SYK: 16.02%
Q3: 14.36%
Median: 5.45%
Q1: -10.67%
Min: -47.01%

Penumbra (PEN) vs. Stryker (SYK): A comparison of their ROE against the Health Care Equipment & Services industry group benchmark.

Net Margin (TTM)

For every dollar of sales, both Penumbra (PEN) at 10.06% and Stryker (SYK) at 13.78% retain more as net profit than most peers, landing in the top net margin quartile of their industries.

PEN

Health Care Equipment & Services industry group

10.06%

Max: 29.35%
PEN: 10.06%
Q3: 9.33%
Median: 2.18%
Q1: -6.29%
Min: -28.46%

SYK

Health Care Equipment & Services industry group

13.78%

Max: 29.35%
SYK: 13.78%
Q3: 9.33%
Median: 2.18%
Q1: -6.29%
Min: -28.46%

Penumbra (PEN) vs. Stryker (SYK): A comparison of their net margin against the Health Care Equipment & Services industry group benchmark.

Operating Margin (TTM)

Stryker (SYK) at 22.96% operates in the top operating margin quartile, ahead of Penumbra (PEN) at 12.37%, which runs around its industry’s norm.

PEN

Health Care Equipment & Services industry group

12.37%

Max: 35.43%
Q3: 14.14%
PEN: 12.37%
Median: 6.81%
Q1: -0.28%
Min: -16.29%

SYK

Health Care Equipment & Services industry group

22.96%

Max: 35.43%
SYK: 22.96%
Q3: 14.14%
Median: 6.81%
Q1: -0.28%
Min: -16.29%

Penumbra (PEN) vs. Stryker (SYK): A comparison of their operating margin against the Health Care Equipment & Services industry group benchmark.

Profitability Metrics

Profitability metrics for Penumbra (PEN) and Stryker (SYK)
Metric	PEN	SYK
ROE (TTM)	10.67%	16.02%
ROA (TTM)	6.28%	8.36%
Net Margin (TTM)	10.06%	13.78%
Operating Margin (TTM)	12.37%	22.96%
Gross Margin (TTM)	67.99%	65.70%

Growth

Revenue Growth

Both Penumbra (PEN) at 17.50% and Stryker (SYK) at 11.16% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

Penumbra (PEN) vs. Stryker (SYK): A comparison of their Revenue Growth across different time periods.

EPS Growth

Penumbra (PEN) at 1,155.56% clears its industry range for EPS growth, a much stronger earnings trajectory than Stryker (SYK) at 8.25%, which is closer to a typical peer reading.

Penumbra (PEN) vs. Stryker (SYK): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Penumbra (PEN) and Stryker (SYK)
Metric	PEN	SYK
Revenue Growth (YoY)	17.50%	11.16%
Revenue Growth (3Y CAGR)	18.33%	10.83%
EPS Growth (YoY)	1,155.56%	8.25%
EPS Growth (3Y CAGR)	--	10.83%

Financial Strength

Current Ratio (MRQ)

Stryker (SYK) at 2.18 keeps current ratio within its industry’s typical mid-range, while Penumbra (PEN) at 5.89 sits above its industry’s typical mid-range — comfortable liquidity, though possibly with more idle current assets relative to peers.

PEN

Health Care Equipment & Services industry group

5.89

Max: 7.59
PEN: 5.89
Q3: 4.00
Median: 1.98
Q1: 1.37
Min: 0.30

SYK

Health Care Equipment & Services industry group

2.18

Max: 7.59
Q3: 4.00
SYK: 2.18
Median: 1.98
Q1: 1.37
Min: 0.30

Penumbra (PEN) vs. Stryker (SYK): A comparison of their current ratio against the Health Care Equipment & Services industry group benchmark.

Debt / Equity (MRQ)

Penumbra (PEN) at 0.13 keeps leverage in the lower industry quartile, while Stryker (SYK) at 0.66 runs a more typical debt-to-equity mix.

PEN

Health Care Equipment & Services industry group

0.13

Max: 1.88
Q3: 0.91
Median: 0.58
Q1: 0.16
PEN: 0.13
Min: 0.00

SYK

Health Care Equipment & Services industry group

0.66

Max: 1.88
Q3: 0.91
SYK: 0.66
Median: 0.58
Q1: 0.16
Min: 0.00

Penumbra (PEN) vs. Stryker (SYK): A comparison of their debt-to-equity ratio against the Health Care Equipment & Services industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Penumbra (PEN) and Stryker (SYK)
Metric	PEN	SYK
Current Ratio (MRQ)	5.89	2.18
Debt / Equity (MRQ)	0.13	0.66
Net Debt / EBITDA	-2.22	1.62

Dividends

Dividend Yield (TTM)

Penumbra (PEN) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Stryker (SYK) reports a yield of 1.05%, ranking against industry peers normally.

PEN

Health Care Equipment & Services industry group

0.00%

PEN: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

SYK

Health Care Equipment & Services industry group

1.05%

SYK: 1.05%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Penumbra (PEN) vs. Stryker (SYK): A comparison of their dividend yield against the Health Care Equipment & Services industry group benchmark.

Dividend Payout Ratio (TTM)

Penumbra (PEN) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Stryker (SYK) reports a payout of 37.49%, ranking against industry peers normally.

PEN

Health Care Equipment & Services industry group

0.00%

PEN: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

SYK

Health Care Equipment & Services industry group

37.49%

SYK: 37.49%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Penumbra (PEN) vs. Stryker (SYK): A comparison of their payout ratio against the Health Care Equipment & Services industry group benchmark.

Dividend Metrics

Dividend metrics for Penumbra (PEN) and Stryker (SYK)
Metric	PEN	SYK
Dividend Yield (TTM)	0.00%	1.05%
Dividend Payout Ratio (TTM)	0.00%	37.49%

Valuation

P/E Ratio (TTM)

Stryker (SYK) at 34.70 is near its industry’s usual P/E ratio, while Penumbra (PEN) at 80.41 sits in the richer quartile — PEN needs stronger growth or earnings quality to justify the premium.

PEN

Health Care Equipment & Services industry group

80.41

PEN: 80.41
Max: 80.41
Q3: 47.62
Median: 29.93
Q1: 21.19
Min: 4.21

SYK

Health Care Equipment & Services industry group

34.70

Max: 80.41
Q3: 47.62
SYK: 34.70
Median: 29.93
Q1: 21.19
Min: 4.21

Penumbra (PEN) vs. Stryker (SYK): A comparison of their P/E ratio against the Health Care Equipment & Services industry group benchmark.

P/S Ratio (TTM)

Both Penumbra (PEN) at 8.06 and Stryker (SYK) at 4.72 command a richer price per dollar of sales than most peers, sitting in the upper P/S ratio quartile of their industries.

PEN

Health Care Equipment & Services industry group

8.06

Max: 8.80
PEN: 8.06
Q3: 4.32
Median: 2.13
Q1: 1.10
Min: 0.03

SYK

Health Care Equipment & Services industry group

4.72

Max: 8.80
SYK: 4.72
Q3: 4.32
Median: 2.13
Q1: 1.10
Min: 0.03

Penumbra (PEN) vs. Stryker (SYK): A comparison of their P/S ratio against the Health Care Equipment & Services industry group benchmark.

P/B Ratio (MRQ)

Stryker (SYK) at 5.29 is valued about in line with its industry on P/B ratio, while Penumbra (PEN) at 7.95 carries an above-peer premium to book — PEN is pricier on assets.

PEN

Health Care Equipment & Services industry group

7.95

Max: 11.68
PEN: 7.95
Q3: 6.12
Median: 3.00
Q1: 1.73
Min: -1.31

SYK

Health Care Equipment & Services industry group

5.29

Max: 11.68
Q3: 6.12
SYK: 5.29
Median: 3.00
Q1: 1.73
Min: -1.31

Penumbra (PEN) vs. Stryker (SYK): A comparison of their P/B ratio against the Health Care Equipment & Services industry group benchmark.

Valuation Metrics

Valuation metrics for Penumbra (PEN) and Stryker (SYK)
Metric	PEN	SYK
P/E Ratio (TTM)	80.41	34.70
P/S Ratio (TTM)	8.06	4.72
P/B Ratio (MRQ)	7.95	5.29
Free Cash Flow Yield (TTM)	1.32%	2.98%