ISRG vs. SYK: Intuitive Surgical vs. Stryker Stock Comparison

July 2, 2026

How do Intuitive Surgical (ISRG) and Stryker (SYK) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Intuitive Surgical (ISRG) and Stryker (SYK) are both classified in the Health Care Equipment sub-industry within the broader Health Care Equipment & Supplies industry, placing them in the closest GICS peer bucket.

Company profile comparison for Intuitive Surgical (ISRG) and Stryker (SYK)
Profile Item	ISRG	SYK
Name	Intuitive Surgical, Inc.	Stryker Corporation
Country/Region	United States	United States
GICS Sector	Health Care	Health Care
GICS Industry Group	Health Care Equipment & Services	Health Care Equipment & Services
GICS Industry	Health Care Equipment & Supplies	Health Care Equipment & Supplies
GICS Sub-Industry	Health Care Equipment	Health Care Equipment
Market Capitalization	140.84 billion USD	120.70 billion USD
Currency	USD	USD
Exchange	Nasdaq	NYSE
Listing Date	June 16, 2000	March 17, 1980
Security Type	Common Stock	Common Stock

Price Performance

Cumulative Growth

ISRG

SYK

Intuitive Surgical (ISRG) vs. Stryker (SYK): Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

Loading price history…

Trailing total returns for Intuitive Surgical (ISRG) and Stryker (SYK). Returns over one year are annualized.

Performance Metrics

Price performance metrics for Intuitive Surgical (ISRG) and Stryker (SYK)
Metric	ISRG	SYK
Total Return (1Y)	-26.82%	-19.61%

Risk Profile

Drawdown History

ISRG

SYK

Intuitive Surgical (ISRG) vs. Stryker (SYK): Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Risk Metrics

Risk profile metrics for Intuitive Surgical (ISRG) and Stryker (SYK)
Metric	ISRG	SYK
Volatility (1Y, Annualized)	30.78%	24.12%
Beta (5Y)	1.46	0.77
Avg. Volume (3M)	2.36M	2.58M

Risk-Adjusted Performance

Risk-Return Positioning

ISRG and SYK are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Profitability

ROE (TTM)

Both Intuitive Surgical (ISRG) at 17.23% and Stryker (SYK) at 15.20% sit in the top peer quartile for ROE, suggesting each generates more profit from shareholders’ equity than typical industry peers.

ISRG

Health Care Equipment & Services industry group

17.23%

Max: 53.65%
ISRG: 17.23%
Q3: 13.38%
Median: 3.66%
Q1: -17.06%
Min: -59.21%

SYK

Health Care Equipment & Services industry group

15.20%

Max: 53.65%
SYK: 15.20%
Q3: 13.38%
Median: 3.66%
Q1: -17.06%
Min: -59.21%

Intuitive Surgical (ISRG) vs. Stryker (SYK): A comparison of their ROE against the Health Care Equipment & Services industry group benchmark.

Net Margin (TTM)

For every dollar of sales, both Intuitive Surgical (ISRG) at 28.15% and Stryker (SYK) at 13.21% retain more as net profit than most peers, landing in the top net margin quartile of their industries.

ISRG

Health Care Equipment & Services industry group

28.15%

Max: 30.40%
ISRG: 28.15%
Q3: 8.04%
Median: 1.52%
Q1: -9.42%
Min: -34.34%

SYK

Health Care Equipment & Services industry group

13.21%

Max: 30.40%
SYK: 13.21%
Q3: 8.04%
Median: 1.52%
Q1: -9.42%
Min: -34.34%

Intuitive Surgical (ISRG) vs. Stryker (SYK): A comparison of their net margin against the Health Care Equipment & Services industry group benchmark.

Operating Margin (TTM)

Both Intuitive Surgical (ISRG) at 30.87% and Stryker (SYK) at 17.82% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

ISRG

Health Care Equipment & Services industry group

30.87%

Max: 37.54%
ISRG: 30.87%
Q3: 12.56%
Median: 5.48%
Q1: -4.26%
Min: -25.61%

SYK

Health Care Equipment & Services industry group

17.82%

Max: 37.54%
SYK: 17.82%
Q3: 12.56%
Median: 5.48%
Q1: -4.26%
Min: -25.61%

Intuitive Surgical (ISRG) vs. Stryker (SYK): A comparison of their operating margin against the Health Care Equipment & Services industry group benchmark.

Profitability Metrics

Profitability metrics for Intuitive Surgical (ISRG) and Stryker (SYK)
Metric	ISRG	SYK
ROE (TTM)	17.23%	15.20%
ROA (TTM)	10.24%	7.72%
Net Margin (TTM)	28.15%	13.21%
Operating Margin (TTM)	30.87%	17.82%
Gross Margin (TTM)	66.29%	64.70%

Growth

Revenue Growth

Intuitive Surgical (ISRG) vs. Stryker (SYK): A comparison of their Revenue Growth across different time periods.

Revenue Growth Metrics

Revenue growth metrics for Intuitive Surgical (ISRG) and Stryker (SYK)
Metric	ISRG	SYK
Revenue Growth (YoY)	20.51%	11.16%
Revenue Growth (3Y CAGR)	17.39%	10.83%

EPS Growth

Intuitive Surgical (ISRG) vs. Stryker (SYK): A comparison of their EPS Growth across different time periods.

EPS Growth Metrics

EPS growth metrics for Intuitive Surgical (ISRG) and Stryker (SYK)
Metric	ISRG	SYK
EPS Growth (YoY)	22.59%	8.25%
EPS Growth (3Y CAGR)	29.19%	10.83%

Financial Strength

Current Ratio (MRQ)

Stryker (SYK) at 2.11 keeps current ratio within its industry’s typical mid-range, while Intuitive Surgical (ISRG) at 4.61 sits above its industry’s typical mid-range — comfortable liquidity, though possibly with more idle current assets relative to peers.

ISRG

Health Care Equipment & Services industry group

4.61

Max: 7.79
ISRG: 4.61
Q3: 4.28
Median: 1.99
Q1: 1.34
Min: 0.04

SYK

Health Care Equipment & Services industry group

2.11

Max: 7.79
Q3: 4.28
SYK: 2.11
Median: 1.99
Q1: 1.34
Min: 0.04

Intuitive Surgical (ISRG) vs. Stryker (SYK): A comparison of their current ratio against the Health Care Equipment & Services industry group benchmark.

Debt / Equity (MRQ)

Only one side’s leverage can be read here: Stryker (SYK) carries debt-to-equity ratio of 0.66 against its industry range, while Intuitive Surgical (ISRG) reports no figure this period.

ISRG

Health Care Equipment & Services industry group

Max: 2.02
Q3: 1.01
Median: 0.60
Q1: 0.15
Min: 0.00
ISRG: --

SYK

Health Care Equipment & Services industry group

0.66

Max: 2.02
Q3: 1.01
SYK: 0.66
Median: 0.60
Q1: 0.15
Min: 0.00

Intuitive Surgical (ISRG) vs. Stryker (SYK): ISRG does not report debt-to-equity ratio, so it has no value marker; SYK is benchmarked against the Health Care Equipment & Services industry group.

Financial Strength Metrics

Financial strength metrics for Intuitive Surgical (ISRG) and Stryker (SYK)
Metric	ISRG	SYK
Current Ratio (MRQ)	4.61	2.11
Debt / Equity (MRQ)	--	0.66
Net Debt / EBITDA	-1.16	1.77

Dividends

Dividend Yield (TTM)

Intuitive Surgical (ISRG) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Stryker (SYK) reports a yield of 1.04%, ranking against industry peers normally.

ISRG

Health Care Equipment & Services industry group

0.00%

ISRG: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

SYK

Health Care Equipment & Services industry group

1.04%

SYK: 1.04%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Intuitive Surgical (ISRG) vs. Stryker (SYK): A comparison of their dividend yield against the Health Care Equipment & Services industry group benchmark.

Dividend Payout Ratio (TTM)

Intuitive Surgical (ISRG) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Stryker (SYK) reports a payout of 39.81%, ranking against industry peers normally.

ISRG

Health Care Equipment & Services industry group

0.00%

ISRG: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

SYK

Health Care Equipment & Services industry group

39.81%

SYK: 39.81%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Intuitive Surgical (ISRG) vs. Stryker (SYK): A comparison of their payout ratio against the Health Care Equipment & Services industry group benchmark.

Dividend Metrics

Dividend metrics for Intuitive Surgical (ISRG) and Stryker (SYK)
Metric	ISRG	SYK
Dividend Yield (TTM)	0.00%	1.04%
Dividend Payout Ratio (TTM)	0.00%	39.81%

Valuation

P/E Ratio (TTM)

Stryker (SYK) at 36.48 is near its industry’s usual P/E ratio, while Intuitive Surgical (ISRG) at 48.32 sits in the richer quartile — ISRG needs stronger growth or earnings quality to justify the premium.

ISRG

Health Care Equipment & Services industry group

48.32

Max: 78.82
ISRG: 48.32
Q3: 46.69
Median: 28.91
Q1: 18.90
Min: 0.97

SYK

Health Care Equipment & Services industry group

36.48

Max: 78.82
Q3: 46.69
SYK: 36.48
Median: 28.91
Q1: 18.90
Min: 0.97

Intuitive Surgical (ISRG) vs. Stryker (SYK): A comparison of their P/E ratio against the Health Care Equipment & Services industry group benchmark.

P/S Ratio (TTM)

Both look expensive on sales: Stryker (SYK) at 4.78 sits in the upper P/S ratio quartile, and Intuitive Surgical (ISRG) at 13.31 prices even higher, above its industry range.

ISRG

Health Care Equipment & Services industry group

13.31

ISRG: 13.31
Max: 9.34
Q3: 4.44
Median: 1.99
Q1: 1.09
Min: 0.04

SYK

Health Care Equipment & Services industry group

4.78

Max: 9.34
SYK: 4.78
Q3: 4.44
Median: 1.99
Q1: 1.09
Min: 0.04

Intuitive Surgical (ISRG) vs. Stryker (SYK): A comparison of their P/S ratio against the Health Care Equipment & Services industry group benchmark.

P/B Ratio (MRQ)

Stryker (SYK) at 5.25 is valued about in line with its industry on P/B ratio, while Intuitive Surgical (ISRG) at 8.07 carries an above-peer premium to book — ISRG is pricier on assets.

ISRG

Health Care Equipment & Services industry group

8.07

Max: 12.16
ISRG: 8.07
Q3: 5.75
Median: 2.87
Q1: 1.48
Min: -2.40

SYK

Health Care Equipment & Services industry group

5.25

Max: 12.16
Q3: 5.75
SYK: 5.25
Median: 2.87
Q1: 1.48
Min: -2.40

Intuitive Surgical (ISRG) vs. Stryker (SYK): A comparison of their P/B ratio against the Health Care Equipment & Services industry group benchmark.

Valuation Metrics

Valuation metrics for Intuitive Surgical (ISRG) and Stryker (SYK)
Metric	ISRG	SYK
P/E Ratio (TTM)	48.32	36.48
P/S Ratio (TTM)	13.31	4.78
P/B Ratio (MRQ)	8.07	5.25
Free Cash Flow Yield (TTM)	1.60%	3.61%