MCK vs. SYK: McKesson vs. Stryker Stock Comparison

June 13, 2026

This page compares McKesson (MCK) with Stryker (SYK) using performance and risk, profitability, financial strength, growth, dividends, and valuation metrics.

Performance

Cumulative Growth

MCK

SYK

McKesson (MCK) vs. Stryker (SYK): Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

Loading price history…

Trailing total returns for McKesson (MCK) and Stryker (SYK). Returns over one year are annualized.

Performance at a Glance

Performance metrics for McKesson (MCK) and Stryker (SYK)
Metric	MCK	SYK
1-Year Return	7.72%	-17.16%

Risk

Drawdown

MCK

SYK

McKesson (MCK) vs. Stryker (SYK): Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Risk at a Glance

Risk metrics for McKesson (MCK) and Stryker (SYK)
Metric	MCK	SYK
1-Year Volatility	29.15%	22.82%
Beta	0.30	0.77
3-Month Avg. Volume	1.01M	2.51M

Company Profile

McKesson (MCK) and Stryker (SYK) both fall under the Health Care Equipment & Services industry group, but MCK is classified in Health Care Providers & Services while SYK is classified in Health Care Equipment & Supplies.

Company profile comparison for McKesson (MCK) and Stryker (SYK)
Profile Item	MCK	SYK
Name	McKesson Corporation	Stryker Corporation
Country/Region	United States	United States
GICS Sector	Health Care	Health Care
GICS Industry Group	Health Care Equipment & Services	Health Care Equipment & Services
GICS Industry	Health Care Providers & Services	Health Care Equipment & Supplies
GICS Sub-Industry	Health Care Distributors	Health Care Equipment
Market Capitalization	94.25 billion USD	119.69 billion USD
Currency	USD	USD
Exchange	NYSE	NYSE
Listing Date	November 10, 1994	March 17, 1980
Security Type	Common Stock	Common Stock

Valuation

Price-to-Earnings Ratio (TTM)

Both McKesson (MCK) at 20.41 and Stryker (SYK) at 36.09 land around their industries’ usual P/E ratio levels — neither is getting a clear earnings-multiple discount or premium versus peers.

MCK

Health Care Equipment & Services industry group

20.41

Max: 80.40
Q3: 44.58
Median: 28.09
MCK: 20.41
Q1: 19.76
Min: 0.91

SYK

Health Care Equipment & Services industry group

36.09

Max: 80.40
Q3: 44.58
SYK: 36.09
Median: 28.09
Q1: 19.76
Min: 0.91

McKesson (MCK) vs. Stryker (SYK): A comparison of their P/E ratio against the Health Care Equipment & Services industry group benchmark.

Price-to-Sales Ratio (TTM)

McKesson (MCK) at 0.23 looks cheap on sales in the lower P/S ratio quartile, while Stryker (SYK) at 4.74 looks rich in the upper quartile — a clear gap in price per dollar of revenue.

MCK

Health Care Equipment & Services industry group

0.23

Max: 8.62
Q3: 4.20
Median: 1.94
Q1: 1.01
MCK: 0.23
Min: 0.04

SYK

Health Care Equipment & Services industry group

4.74

Max: 8.62
SYK: 4.74
Q3: 4.20
Median: 1.94
Q1: 1.01
Min: 0.04

McKesson (MCK) vs. Stryker (SYK): A comparison of their P/S ratio against the Health Care Equipment & Services industry group benchmark.

Price-to-Book Ratio (MRQ)

McKesson (MCK) reports a negative P/B ratio of -43.32, meaning negative book equity — the multiple itself is not meaningful for valuation. Meanwhile Stryker (SYK) reports 5.33, ranking against industry peers normally.

MCK

Health Care Equipment & Services industry group

-43.32

Max: 11.03
Q3: 5.50
Median: 2.78
Q1: 1.47
Min: -2.18
MCK: -43.32

SYK

Health Care Equipment & Services industry group

5.33

Max: 11.03
Q3: 5.50
SYK: 5.33
Median: 2.78
Q1: 1.47
Min: -2.18

McKesson (MCK) vs. Stryker (SYK): A comparison of their P/B ratio against the Health Care Equipment & Services industry group benchmark.

Valuation at a Glance

Valuation metrics for McKesson (MCK) and Stryker (SYK)
Metric	MCK	SYK
Price-to-Earnings Ratio (TTM)	20.41	36.09
Price-to-Sales Ratio (TTM)	0.23	4.74
Price-to-Book Ratio (MRQ)	-43.32	5.33
Free Cash Flow Yield	6.00%	3.64%

Profitability

Return on Equity (TTM)

Capital efficiency shows on one side only: Stryker (SYK) earns 15.20% on shareholders’ equity, ranked against its industry; McKesson (MCK) has no ROE this period.

MCK

Health Care Equipment & Services industry group

Max: 53.65%
Q3: 12.73%
Median: 3.57%
Q1: -17.96%
Min: -59.21%
MCK: --

SYK

Health Care Equipment & Services industry group

15.20%

Max: 53.65%
SYK: 15.20%
Q3: 12.73%
Median: 3.57%
Q1: -17.96%
Min: -59.21%

McKesson (MCK) vs. Stryker (SYK): MCK does not report ROE, so it has no value marker; SYK is benchmarked against the Health Care Equipment & Services industry group.

Net Profit Margin (TTM)

Stryker (SYK) at 13.21% retains a top-quartile share of revenue as profit, ahead of McKesson (MCK) at 1.18%, which keeps about the industry-typical share.

MCK

Health Care Equipment & Services industry group

1.18%

Max: 30.40%
Q3: 7.96%
Median: 1.27%
MCK: 1.18%
Q1: -9.77%
Min: -34.34%

SYK

Health Care Equipment & Services industry group

13.21%

Max: 30.40%
SYK: 13.21%
Q3: 7.96%
Median: 1.27%
Q1: -9.77%
Min: -34.34%

McKesson (MCK) vs. Stryker (SYK): A comparison of their net margin against the Health Care Equipment & Services industry group benchmark.

Operating Profit Margin (TTM)

Stryker (SYK) at 17.82% operates in the top operating margin quartile, ahead of McKesson (MCK) at 2.21%, which runs around its industry’s norm.

MCK

Health Care Equipment & Services industry group

2.21%

Max: 35.33%
Q3: 11.89%
Median: 5.44%
MCK: 2.21%
Q1: -4.59%
Min: -25.61%

SYK

Health Care Equipment & Services industry group

17.82%

Max: 35.33%
SYK: 17.82%
Q3: 11.89%
Median: 5.44%
Q1: -4.59%
Min: -25.61%

McKesson (MCK) vs. Stryker (SYK): A comparison of their operating margin against the Health Care Equipment & Services industry group benchmark.

Profitability at a Glance

Profitability metrics for McKesson (MCK) and Stryker (SYK)
Metric	MCK	SYK
Return on Equity (TTM)	--	15.20%
Return on Assets (TTM)	4.99%	7.72%
Net Profit Margin (TTM)	1.18%	13.21%
Operating Profit Margin (TTM)	2.21%	17.82%
Gross Profit Margin (TTM)	3.60%	64.70%

Growth

Revenue Growth

McKesson (MCK) vs. Stryker (SYK): A comparison of their Revenue Growth across different time periods.

Revenue Growth at a Glance

Revenue growth metrics for McKesson (MCK) and Stryker (SYK)
Metric	MCK	SYK
1-Year Revenue Growth	12.36%	11.16%
3-Year Revenue CAGR	13.39%	10.83%

EPS Growth

McKesson (MCK) vs. Stryker (SYK): A comparison of their EPS Growth across different time periods.

EPS Growth at a Glance

EPS growth metrics for McKesson (MCK) and Stryker (SYK)
Metric	MCK	SYK
1-Year EPS Growth	49.22%	8.25%
3-Year EPS CAGR	15.31%	10.83%

Financial Strength

Current Ratio (MRQ)

Stryker (SYK) at 2.11 keeps current ratio within its industry’s typical mid-range, while McKesson (MCK) at 0.85 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for MCK.

MCK

Health Care Equipment & Services industry group

0.85

Max: 7.79
Q3: 4.29
Median: 1.95
Q1: 1.33
MCK: 0.85
Min: 0.04

SYK

Health Care Equipment & Services industry group

2.11

Max: 7.79
Q3: 4.29
SYK: 2.11
Median: 1.95
Q1: 1.33
Min: 0.04

McKesson (MCK) vs. Stryker (SYK): A comparison of their current ratio against the Health Care Equipment & Services industry group benchmark.

Debt-to-Equity Ratio (MRQ)

Only one side’s leverage can be read here: Stryker (SYK) carries debt-to-equity ratio of 0.66 against its industry range, while McKesson (MCK) reports no figure this period.

MCK

Health Care Equipment & Services industry group

Max: 2.02
Q3: 1.01
Median: 0.60
Q1: 0.16
Min: 0.00
MCK: --

SYK

Health Care Equipment & Services industry group

0.66

Max: 2.02
Q3: 1.01
SYK: 0.66
Median: 0.60
Q1: 0.16
Min: 0.00

McKesson (MCK) vs. Stryker (SYK): MCK does not report debt-to-equity ratio, so it has no value marker; SYK is benchmarked against the Health Care Equipment & Services industry group.

Financial Strength at a Glance

Financial strength metrics for McKesson (MCK) and Stryker (SYK)
Metric	MCK	SYK
Current Ratio (MRQ)	0.85	2.11
Debt-to-Equity Ratio (MRQ)	--	0.66
Net Debt / EBITDA	0.70	1.77

Dividends

Dividend Yield (TTM)

Both McKesson (MCK) at 0.42% and Stryker (SYK) at 1.13% yield above their industries’ entire benchmark ranges — high enough that dividend safety, not income, becomes the first question.

MCK

Health Care Equipment & Services industry group

0.42%

MCK: 0.42%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

SYK

Health Care Equipment & Services industry group

1.13%

SYK: 1.13%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

McKesson (MCK) vs. Stryker (SYK): A comparison of their dividend yield against the Health Care Equipment & Services industry group benchmark.

Dividend Payout Ratio (TTM)

Both McKesson (MCK) at 8.26% and Stryker (SYK) at 39.81% pay out more of their earnings than any of their industry peers — the thinnest cover in their groups, so dividend headroom deserves attention.

MCK

Health Care Equipment & Services industry group

8.26%

MCK: 8.26%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

SYK

Health Care Equipment & Services industry group

39.81%

SYK: 39.81%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

McKesson (MCK) vs. Stryker (SYK): A comparison of their payout ratio against the Health Care Equipment & Services industry group benchmark.

Dividends at a Glance

Dividend metrics for McKesson (MCK) and Stryker (SYK)
Metric	MCK	SYK
Dividend Yield (TTM)	0.42%	1.13%
Dividend Payout Ratio (TTM)	8.26%	39.81%