GKOS vs. SYK: Glaukos vs. Stryker Stock Comparison

November 11, 2026

How do Glaukos (GKOS) and Stryker (SYK) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Glaukos (GKOS) and Stryker (SYK) are both classified in the Health Care Equipment sub-industry within the broader Health Care Equipment & Supplies industry, placing them in the closest GICS peer bucket.

Company profile comparison for Glaukos (GKOS) and Stryker (SYK)
Profile Item	GKOS	SYK
Name	Glaukos Corp.	Stryker Corp.
Country/Region	United States	United States
GICS Sector	Health Care	Health Care
GICS Industry Group	Health Care Equipment & Services	Health Care Equipment & Services
GICS Industry	Health Care Equipment & Supplies	Health Care Equipment & Supplies
GICS Sub-Industry	Health Care Equipment	Health Care Equipment
Market Capitalization	13.28 billion USD	124.06 billion USD
Currency	USD	USD
Exchange	NYSE	NYSE
Listing Date	June 25, 2015	March 17, 1980
Security Type	Common Stock	Common Stock

Price Performance

Cumulative Growth

GKOS

SYK

GSPC

Glaukos (GKOS) vs. Stryker (SYK), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Glaukos (GKOS) and Stryker (SYK). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Glaukos (GKOS) and Stryker (SYK). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Glaukos (GKOS) and Stryker (SYK)
Metric	GKOS	SYK
Total Return (1Y)	179.91%	-6.99%
Total Return (3Y, Annualized)	55.51%	7.60%
Total Return (5Y, Annualized)	35.14%	4.64%

Risk Profile

Drawdown History

GKOS

SYK

GSPC

Glaukos (GKOS) vs. Stryker (SYK), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Glaukos (GKOS) and Stryker (SYK). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Glaukos (GKOS) and Stryker (SYK)
Metric	GKOS	SYK
Volatility (1Y, Annualized)	61.24%	32.80%
Beta (5Y)	0.68	0.72
Max Drawdown (5Y)	-53.68%	-32.47%
Avg. Volume (3M)	1.15M	2.81M

Risk-Adjusted Performance

Risk-Return Positioning

GKOS and SYK are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Glaukos (GKOS) and Stryker (SYK)
Metric	GKOS	SYK
Sharpe Ratio (1Y)	2.87	-0.34
Sortino Ratio (1Y)	5.93	-0.49

Profitability

ROE (TTM)

Glaukos (GKOS) reports a negative ROE of -22.84%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile Stryker (SYK) reports 16.02%, ranking against industry peers normally.

GKOS

Health Care Equipment & Services industry group

-22.84%

Max: 47.61%
Q3: 14.36%
Median: 5.45%
Q1: -10.67%
GKOS: -22.84%
Min: -47.01%

SYK

Health Care Equipment & Services industry group

16.02%

Max: 47.61%
SYK: 16.02%
Q3: 14.36%
Median: 5.45%
Q1: -10.67%
Min: -47.01%

Glaukos (GKOS) vs. Stryker (SYK): A comparison of their ROE against the Health Care Equipment & Services industry group benchmark.

Net Margin (TTM)

Glaukos (GKOS) reports a negative net margin of -24.60%, usually indicating a net loss over the period. Meanwhile Stryker (SYK) reports 13.78%, ranking against industry peers normally.

GKOS

Health Care Equipment & Services industry group

-24.60%

Max: 29.35%
Q3: 9.33%
Median: 2.18%
Q1: -6.29%
GKOS: -24.60%
Min: -28.46%

SYK

Health Care Equipment & Services industry group

13.78%

Max: 29.35%
SYK: 13.78%
Q3: 9.33%
Median: 2.18%
Q1: -6.29%
Min: -28.46%

Glaukos (GKOS) vs. Stryker (SYK): A comparison of their net margin against the Health Care Equipment & Services industry group benchmark.

Operating Margin (TTM)

Stryker (SYK) at 22.96% operates in the top operating margin quartile, ahead of Glaukos (GKOS) at 0.39%, which runs around its industry’s norm.

GKOS

Health Care Equipment & Services industry group

0.39%

Max: 35.43%
Q3: 14.14%
Median: 6.81%
GKOS: 0.39%
Q1: -0.28%
Min: -16.29%

SYK

Health Care Equipment & Services industry group

22.96%

Max: 35.43%
SYK: 22.96%
Q3: 14.14%
Median: 6.81%
Q1: -0.28%
Min: -16.29%

Glaukos (GKOS) vs. Stryker (SYK): A comparison of their operating margin against the Health Care Equipment & Services industry group benchmark.

Profitability Metrics

Profitability metrics for Glaukos (GKOS) and Stryker (SYK)
Metric	GKOS	SYK
ROE (TTM)	-22.84%	16.02%
ROA (TTM)	-3.90%	8.36%
Net Margin (TTM)	-24.60%	13.78%
Operating Margin (TTM)	0.39%	22.96%
Gross Margin (TTM)	81.13%	65.70%

Growth

Revenue Growth

Glaukos (GKOS) at 32.33% sits in the top revenue growth quartile, while Stryker (SYK) at 11.16% is closer to the peer norm — faster top-line expansion for GKOS.

Glaukos (GKOS) vs. Stryker (SYK): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: Stryker (SYK) reports EPS growth of 8.25%, ranked against its industry; Glaukos (GKOS) has no EPS growth figure this period.

Glaukos (GKOS) vs. Stryker (SYK): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Glaukos (GKOS) and Stryker (SYK)
Metric	GKOS	SYK
Revenue Growth (YoY)	32.33%	11.16%
Revenue Growth (3Y CAGR)	21.51%	10.83%
EPS Growth (YoY)	--	8.25%
EPS Growth (3Y CAGR)	--	10.83%

Financial Strength

Current Ratio (MRQ)

Stryker (SYK) at 2.18 keeps current ratio within its industry’s typical mid-range, while Glaukos (GKOS) at 4.57 sits above its industry’s typical mid-range — comfortable liquidity, though possibly with more idle current assets relative to peers.

GKOS

Health Care Equipment & Services industry group

4.57

Max: 7.59
GKOS: 4.57
Q3: 4.00
Median: 1.98
Q1: 1.37
Min: 0.30

SYK

Health Care Equipment & Services industry group

2.18

Max: 7.59
Q3: 4.00
SYK: 2.18
Median: 1.98
Q1: 1.37
Min: 0.30

Glaukos (GKOS) vs. Stryker (SYK): A comparison of their current ratio against the Health Care Equipment & Services industry group benchmark.

Debt / Equity (MRQ)

Glaukos (GKOS) at 0.15 keeps leverage in the lower industry quartile, while Stryker (SYK) at 0.66 runs a more typical debt-to-equity mix.

GKOS

Health Care Equipment & Services industry group

0.15

Max: 1.88
Q3: 0.91
Median: 0.58
Q1: 0.16
GKOS: 0.15
Min: 0.00

SYK

Health Care Equipment & Services industry group

0.66

Max: 1.88
Q3: 0.91
SYK: 0.66
Median: 0.58
Q1: 0.16
Min: 0.00

Glaukos (GKOS) vs. Stryker (SYK): A comparison of their debt-to-equity ratio against the Health Care Equipment & Services industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Glaukos (GKOS) and Stryker (SYK)
Metric	GKOS	SYK
Current Ratio (MRQ)	4.57	2.18
Debt / Equity (MRQ)	0.15	0.66
Net Debt / EBITDA	--	1.62

Dividends

Dividend Yield (TTM)

Glaukos (GKOS) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Stryker (SYK) reports a yield of 1.05%, ranking against industry peers normally.

GKOS

Health Care Equipment & Services industry group

0.00%

GKOS: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

SYK

Health Care Equipment & Services industry group

1.05%

SYK: 1.05%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Glaukos (GKOS) vs. Stryker (SYK): A comparison of their dividend yield against the Health Care Equipment & Services industry group benchmark.

Dividend Payout Ratio (TTM)

Glaukos (GKOS) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Stryker (SYK) reports a payout of 37.49%, ranking against industry peers normally.

GKOS

Health Care Equipment & Services industry group

0.00%

GKOS: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

SYK

Health Care Equipment & Services industry group

37.49%

SYK: 37.49%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Glaukos (GKOS) vs. Stryker (SYK): A comparison of their payout ratio against the Health Care Equipment & Services industry group benchmark.

Dividend Metrics

Dividend metrics for Glaukos (GKOS) and Stryker (SYK)
Metric	GKOS	SYK
Dividend Yield (TTM)	0.00%	1.05%
Dividend Payout Ratio (TTM)	0.00%	37.49%

Valuation

P/E Ratio (TTM)

An earnings multiple is available for just one side: Stryker (SYK) trades at 34.70 times trailing earnings, ranked against its peers, while Glaukos (GKOS) has no P/E ratio this period.

GKOS

Health Care Equipment & Services industry group

Max: 80.41
Q3: 47.62
Median: 29.93
Q1: 21.19
Min: 4.21
GKOS: --

SYK

Health Care Equipment & Services industry group

34.70

Max: 80.41
Q3: 47.62
SYK: 34.70
Median: 29.93
Q1: 21.19
Min: 4.21

Glaukos (GKOS) vs. Stryker (SYK): GKOS does not report P/E ratio, so it has no value marker; SYK is benchmarked against the Health Care Equipment & Services industry group.

P/S Ratio (TTM)

Both look expensive on sales: Stryker (SYK) at 4.72 sits in the upper P/S ratio quartile, and Glaukos (GKOS) at 19.24 prices even higher, above its industry range.

GKOS

Health Care Equipment & Services industry group

19.24

GKOS: 19.24
Max: 8.80
Q3: 4.32
Median: 2.13
Q1: 1.10
Min: 0.03

SYK

Health Care Equipment & Services industry group

4.72

Max: 8.80
SYK: 4.72
Q3: 4.32
Median: 2.13
Q1: 1.10
Min: 0.03

Glaukos (GKOS) vs. Stryker (SYK): A comparison of their P/S ratio against the Health Care Equipment & Services industry group benchmark.

P/B Ratio (MRQ)

Stryker (SYK) at 5.29 sits near its industry’s typical P/B ratio, while Glaukos (GKOS) at 18.51 prices above its benchmark range — GKOS looks rich relative to book.

GKOS

Health Care Equipment & Services industry group

18.51

GKOS: 18.51
Max: 11.68
Q3: 6.12
Median: 3.00
Q1: 1.73
Min: -1.31

SYK

Health Care Equipment & Services industry group

5.29

Max: 11.68
Q3: 6.12
SYK: 5.29
Median: 3.00
Q1: 1.73
Min: -1.31

Glaukos (GKOS) vs. Stryker (SYK): A comparison of their P/B ratio against the Health Care Equipment & Services industry group benchmark.

Valuation Metrics

Valuation metrics for Glaukos (GKOS) and Stryker (SYK)
Metric	GKOS	SYK
P/E Ratio (TTM)	--	34.70
P/S Ratio (TTM)	19.24	4.72
P/B Ratio (MRQ)	18.51	5.29
Free Cash Flow Yield (TTM)	0.40%	2.98%