GKOS vs. ISRG: Glaukos vs. Intuitive Surgical Stock Comparison
How do Glaukos (GKOS) and Intuitive Surgical (ISRG) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.
Company Profile
Glaukos (GKOS) and Intuitive Surgical (ISRG) are both classified in the Health Care Equipment sub-industry within the broader Health Care Equipment & Supplies industry, placing them in the closest GICS peer bucket.
| Profile Item | GKOS | ISRG |
|---|---|---|
| Name | Glaukos Corp. | Intuitive Surgical Inc. |
| Country/Region | United States | United States |
| GICS Sector | Health Care | Health Care |
| GICS Industry Group | Health Care Equipment & Services | Health Care Equipment & Services |
| GICS Industry | Health Care Equipment & Supplies | Health Care Equipment & Supplies |
| GICS Sub-Industry | Health Care Equipment | Health Care Equipment |
| Market Capitalization | 13.28 billion USD | 159.96 billion USD |
| Currency | USD | USD |
| Exchange | NYSE | Nasdaq |
| Listing Date | June 25, 2015 | June 16, 2000 |
| Security Type | Common Stock | Common Stock |
Price Performance
Cumulative Growth
Trailing Returns
Calendar-Year Returns
Performance Metrics
| Metric | GKOS | ISRG |
|---|---|---|
| Total Return (1Y) | 179.91% | -17.61% |
| Total Return (3Y, Annualized) | 55.51% | 19.20% |
| Total Return (5Y, Annualized) | 35.14% | 4.85% |
Risk Profile
Drawdown History
Return Distribution
Risk Metrics
Intuitive Surgical (ISRG) has an aggressive beta of 1.41, indicating higher sensitivity to broad-market moves, while Glaukos (GKOS) is defensive at 0.68 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.
| Metric | GKOS | ISRG |
|---|---|---|
| Volatility (1Y, Annualized) | 61.24% | 35.53% |
| Beta (5Y) | 0.68 | 1.41 |
| Max Drawdown (5Y) | -53.68% | -49.88% |
| Avg. Volume (3M) | 1.15M | 2.43M |
Risk-Adjusted Performance
Risk-Return Positioning
Risk-Adjusted Metrics
| Metric | GKOS | ISRG |
|---|---|---|
| Sharpe Ratio (1Y) | 2.87 | -0.62 |
| Sortino Ratio (1Y) | 5.93 | -0.83 |
Profitability
ROE (TTM)
Glaukos (GKOS) reports a negative ROE of -22.84%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile Intuitive Surgical (ISRG) reports 17.93%, ranking against industry peers normally.
GKOS
Health Care Equipment & Services industry group
-22.84%
- Max
- 47.61%
- Q3
- 14.36%
- Median
- 5.45%
- Q1
- -10.67%
- GKOS
- -22.84%
- Min
- -47.01%
ISRG
Health Care Equipment & Services industry group
17.93%
- Max
- 47.61%
- ISRG
- 17.93%
- Q3
- 14.36%
- Median
- 5.45%
- Q1
- -10.67%
- Min
- -47.01%
Net Margin (TTM)
Glaukos (GKOS) reports a negative net margin of -24.60%, usually indicating a net loss over the period. Meanwhile Intuitive Surgical (ISRG) reports 25.54%, ranking against industry peers normally.
GKOS
Health Care Equipment & Services industry group
-24.60%
- Max
- 29.35%
- Q3
- 9.33%
- Median
- 2.18%
- Q1
- -6.29%
- GKOS
- -24.60%
- Min
- -28.46%
ISRG
Health Care Equipment & Services industry group
25.54%
- Max
- 29.35%
- ISRG
- 25.54%
- Q3
- 9.33%
- Median
- 2.18%
- Q1
- -6.29%
- Min
- -28.46%
Operating Margin (TTM)
Intuitive Surgical (ISRG) at 33.29% operates in the top operating margin quartile, ahead of Glaukos (GKOS) at 0.39%, which runs around its industry’s norm.
GKOS
Health Care Equipment & Services industry group
0.39%
- Max
- 35.43%
- Q3
- 14.14%
- Median
- 6.81%
- GKOS
- 0.39%
- Q1
- -0.28%
- Min
- -16.29%
ISRG
Health Care Equipment & Services industry group
33.29%
- Max
- 35.43%
- ISRG
- 33.29%
- Q3
- 14.14%
- Median
- 6.81%
- Q1
- -0.28%
- Min
- -16.29%
Profitability Metrics
| Metric | GKOS | ISRG |
|---|---|---|
| ROE (TTM) | -22.84% | 17.93% |
| ROA (TTM) | -3.90% | 11.86% |
| Net Margin (TTM) | -24.60% | 25.54% |
| Operating Margin (TTM) | 0.39% | 33.29% |
| Gross Margin (TTM) | 81.13% | 66.64% |
Growth
Revenue Growth
Both Glaukos (GKOS) at 32.33% and Intuitive Surgical (ISRG) at 20.51% sit in the top peer quartile for revenue growth, so each is growing its top line faster than typical industry peers.
EPS Growth
Only one side can be read here: Intuitive Surgical (ISRG) reports EPS growth of 22.59%, ranked against its industry; Glaukos (GKOS) has no EPS growth figure this period.
Growth Metrics
| Metric | GKOS | ISRG |
|---|---|---|
| Revenue Growth (YoY) | 32.33% | 20.51% |
| Revenue Growth (3Y CAGR) | 21.51% | 17.39% |
| EPS Growth (YoY) | -- | 22.59% |
| EPS Growth (3Y CAGR) | -- | 29.19% |
Financial Strength
Current Ratio (MRQ)
Intuitive Surgical (ISRG) at 3.33 keeps current ratio within its industry’s typical mid-range, while Glaukos (GKOS) at 4.57 sits above its industry’s typical mid-range — comfortable liquidity, though possibly with more idle current assets relative to peers.
GKOS
Health Care Equipment & Services industry group
4.57
- Max
- 7.59
- GKOS
- 4.57
- Q3
- 4.00
- Median
- 1.98
- Q1
- 1.37
- Min
- 0.30
ISRG
Health Care Equipment & Services industry group
3.33
- Max
- 7.59
- Q3
- 4.00
- ISRG
- 3.33
- Median
- 1.98
- Q1
- 1.37
- Min
- 0.30
Debt / Equity (MRQ)
Only one side’s leverage can be read here: Glaukos (GKOS) carries debt-to-equity ratio of 0.15 against its industry range, while Intuitive Surgical (ISRG) reports no figure this period.
GKOS
Health Care Equipment & Services industry group
0.15
- Max
- 1.88
- Q3
- 0.91
- Median
- 0.58
- Q1
- 0.16
- GKOS
- 0.15
- Min
- 0.00
ISRG
Health Care Equipment & Services industry group
--
- Max
- 1.88
- Q3
- 0.91
- Median
- 0.58
- Q1
- 0.16
- Min
- 0.00
- ISRG
- --
Financial Strength Metrics
| Metric | GKOS | ISRG |
|---|---|---|
| Current Ratio (MRQ) | 4.57 | 3.33 |
| Debt / Equity (MRQ) | 0.15 | -- |
| Net Debt / EBITDA | -- | -0.90 |
Dividends
Dividend Yield (TTM)
Neither Glaukos (GKOS) nor Intuitive Surgical (ISRG) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.
GKOS
Health Care Equipment & Services industry group
0.00%
- GKOS
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
ISRG
Health Care Equipment & Services industry group
0.00%
- ISRG
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Payout Ratio (TTM)
Neither Glaukos (GKOS) nor Intuitive Surgical (ISRG) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.
GKOS
Health Care Equipment & Services industry group
0.00%
- GKOS
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
ISRG
Health Care Equipment & Services industry group
0.00%
- ISRG
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Metrics
| Metric | GKOS | ISRG |
|---|---|---|
| Dividend Yield (TTM) | 0.00% | 0.00% |
| Dividend Payout Ratio (TTM) | 0.00% | 0.00% |
Valuation
P/E Ratio (TTM)
An earnings multiple is available for just one side: Intuitive Surgical (ISRG) trades at 54.75 times trailing earnings, ranked against its peers, while Glaukos (GKOS) has no P/E ratio this period.
GKOS
Health Care Equipment & Services industry group
--
- Max
- 80.41
- Q3
- 47.62
- Median
- 29.93
- Q1
- 21.19
- Min
- 4.21
- GKOS
- --
ISRG
Health Care Equipment & Services industry group
54.75
- Max
- 80.41
- ISRG
- 54.75
- Q3
- 47.62
- Median
- 29.93
- Q1
- 21.19
- Min
- 4.21
P/S Ratio (TTM)
Investors are paying well above the peer range per dollar of sales for both Glaukos (GKOS) at 19.24 and Intuitive Surgical (ISRG) at 13.82 — each P/S ratio clears its industry’s benchmark range.
GKOS
Health Care Equipment & Services industry group
19.24
- GKOS
- 19.24
- Max
- 8.80
- Q3
- 4.32
- Median
- 2.13
- Q1
- 1.10
- Min
- 0.03
ISRG
Health Care Equipment & Services industry group
13.82
- ISRG
- 13.82
- Max
- 8.80
- Q3
- 4.32
- Median
- 2.13
- Q1
- 1.10
- Min
- 0.03
P/B Ratio (MRQ)
Both look rich against book: Intuitive Surgical (ISRG) at 9.82 sits in the upper P/B ratio quartile, and Glaukos (GKOS) at 18.51 prices even higher, above its industry range.
GKOS
Health Care Equipment & Services industry group
18.51
- GKOS
- 18.51
- Max
- 11.68
- Q3
- 6.12
- Median
- 3.00
- Q1
- 1.73
- Min
- -1.31
ISRG
Health Care Equipment & Services industry group
9.82
- Max
- 11.68
- ISRG
- 9.82
- Q3
- 6.12
- Median
- 3.00
- Q1
- 1.73
- Min
- -1.31
Valuation Metrics
| Metric | GKOS | ISRG |
|---|---|---|
| P/E Ratio (TTM) | -- | 54.75 |
| P/S Ratio (TTM) | 19.24 | 13.82 |
| P/B Ratio (MRQ) | 18.51 | 9.82 |
| Free Cash Flow Yield (TTM) | 0.40% | 2.15% |