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GKOS vs. ISRG: Glaukos vs. Intuitive Surgical Stock Comparison

How do Glaukos (GKOS) and Intuitive Surgical (ISRG) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Glaukos (GKOS) and Intuitive Surgical (ISRG) are both classified in the Health Care Equipment sub-industry within the broader Health Care Equipment & Supplies industry, placing them in the closest GICS peer bucket.

Company profile comparison for Glaukos (GKOS) and Intuitive Surgical (ISRG)
Profile ItemGKOSISRG
NameGlaukos Corp.Intuitive Surgical Inc.
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupHealth Care Equipment & ServicesHealth Care Equipment & Services
GICS IndustryHealth Care Equipment & SuppliesHealth Care Equipment & Supplies
GICS Sub-IndustryHealth Care EquipmentHealth Care Equipment
Market Capitalization13.28 billion USD159.96 billion USD
CurrencyUSDUSD
ExchangeNYSENasdaq
Listing DateJune 25, 2015June 16, 2000
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

GKOS
ISRG
GSPC
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Glaukos (GKOS) vs. Intuitive Surgical (ISRG), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Glaukos (GKOS) and Intuitive Surgical (ISRG). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Glaukos (GKOS) and Intuitive Surgical (ISRG). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Glaukos (GKOS) and Intuitive Surgical (ISRG)
MetricGKOSISRG
Total Return (1Y)179.91%-17.61%
Total Return (3Y, Annualized)55.51%19.20%
Total Return (5Y, Annualized)35.14%4.85%

Risk Profile

Drawdown History

GKOS
ISRG
GSPC
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Glaukos (GKOS) vs. Intuitive Surgical (ISRG), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Glaukos (GKOS) and Intuitive Surgical (ISRG). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Intuitive Surgical (ISRG) has an aggressive beta of 1.41, indicating higher sensitivity to broad-market moves, while Glaukos (GKOS) is defensive at 0.68 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.

Risk profile metrics for Glaukos (GKOS) and Intuitive Surgical (ISRG)
MetricGKOSISRG
Volatility (1Y, Annualized)61.24%35.53%
Beta (5Y)0.681.41
Max Drawdown (5Y)-53.68%-49.88%
Avg. Volume (3M)1.15M2.43M

Risk-Adjusted Performance

Risk-Return Positioning

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GKOS and ISRG are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Glaukos (GKOS) and Intuitive Surgical (ISRG)
MetricGKOSISRG
Sharpe Ratio (1Y)2.87-0.62
Sortino Ratio (1Y)5.93-0.83

Profitability

ROE (TTM)

Glaukos (GKOS) reports a negative ROE of -22.84%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile Intuitive Surgical (ISRG) reports 17.93%, ranking against industry peers normally.

GKOS

Health Care Equipment & Services industry group

-22.84%

Max
47.61%
Q3
14.36%
Median
5.45%
Q1
-10.67%
GKOS
-22.84%
Min
-47.01%

ISRG

Health Care Equipment & Services industry group

17.93%

Max
47.61%
ISRG
17.93%
Q3
14.36%
Median
5.45%
Q1
-10.67%
Min
-47.01%
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Glaukos (GKOS) vs. Intuitive Surgical (ISRG): A comparison of their ROE against the Health Care Equipment & Services industry group benchmark.

Net Margin (TTM)

Glaukos (GKOS) reports a negative net margin of -24.60%, usually indicating a net loss over the period. Meanwhile Intuitive Surgical (ISRG) reports 25.54%, ranking against industry peers normally.

GKOS

Health Care Equipment & Services industry group

-24.60%

Max
29.35%
Q3
9.33%
Median
2.18%
Q1
-6.29%
GKOS
-24.60%
Min
-28.46%

ISRG

Health Care Equipment & Services industry group

25.54%

Max
29.35%
ISRG
25.54%
Q3
9.33%
Median
2.18%
Q1
-6.29%
Min
-28.46%
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Glaukos (GKOS) vs. Intuitive Surgical (ISRG): A comparison of their net margin against the Health Care Equipment & Services industry group benchmark.

Operating Margin (TTM)

Intuitive Surgical (ISRG) at 33.29% operates in the top operating margin quartile, ahead of Glaukos (GKOS) at 0.39%, which runs around its industry’s norm.

GKOS

Health Care Equipment & Services industry group

0.39%

Max
35.43%
Q3
14.14%
Median
6.81%
GKOS
0.39%
Q1
-0.28%
Min
-16.29%

ISRG

Health Care Equipment & Services industry group

33.29%

Max
35.43%
ISRG
33.29%
Q3
14.14%
Median
6.81%
Q1
-0.28%
Min
-16.29%
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Glaukos (GKOS) vs. Intuitive Surgical (ISRG): A comparison of their operating margin against the Health Care Equipment & Services industry group benchmark.

Profitability Metrics

Profitability metrics for Glaukos (GKOS) and Intuitive Surgical (ISRG)
MetricGKOSISRG
ROE (TTM)-22.84%17.93%
ROA (TTM)-3.90%11.86%
Net Margin (TTM)-24.60%25.54%
Operating Margin (TTM)0.39%33.29%
Gross Margin (TTM)81.13%66.64%

Growth

Revenue Growth

Both Glaukos (GKOS) at 32.33% and Intuitive Surgical (ISRG) at 20.51% sit in the top peer quartile for revenue growth, so each is growing its top line faster than typical industry peers.

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Glaukos (GKOS) vs. Intuitive Surgical (ISRG): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: Intuitive Surgical (ISRG) reports EPS growth of 22.59%, ranked against its industry; Glaukos (GKOS) has no EPS growth figure this period.

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Glaukos (GKOS) vs. Intuitive Surgical (ISRG): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Glaukos (GKOS) and Intuitive Surgical (ISRG)
MetricGKOSISRG
Revenue Growth (YoY)32.33%20.51%
Revenue Growth (3Y CAGR)21.51%17.39%
EPS Growth (YoY)--22.59%
EPS Growth (3Y CAGR)--29.19%

Financial Strength

Current Ratio (MRQ)

Intuitive Surgical (ISRG) at 3.33 keeps current ratio within its industry’s typical mid-range, while Glaukos (GKOS) at 4.57 sits above its industry’s typical mid-range — comfortable liquidity, though possibly with more idle current assets relative to peers.

GKOS

Health Care Equipment & Services industry group

4.57

Max
7.59
GKOS
4.57
Q3
4.00
Median
1.98
Q1
1.37
Min
0.30

ISRG

Health Care Equipment & Services industry group

3.33

Max
7.59
Q3
4.00
ISRG
3.33
Median
1.98
Q1
1.37
Min
0.30
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Glaukos (GKOS) vs. Intuitive Surgical (ISRG): A comparison of their current ratio against the Health Care Equipment & Services industry group benchmark.

Debt / Equity (MRQ)

Only one side’s leverage can be read here: Glaukos (GKOS) carries debt-to-equity ratio of 0.15 against its industry range, while Intuitive Surgical (ISRG) reports no figure this period.

GKOS

Health Care Equipment & Services industry group

0.15

Max
1.88
Q3
0.91
Median
0.58
Q1
0.16
GKOS
0.15
Min
0.00

ISRG

Health Care Equipment & Services industry group

--

Max
1.88
Q3
0.91
Median
0.58
Q1
0.16
Min
0.00
ISRG
--
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Glaukos (GKOS) vs. Intuitive Surgical (ISRG): ISRG does not report debt-to-equity ratio, so it has no value marker; GKOS is benchmarked against the Health Care Equipment & Services industry group.

Financial Strength Metrics

Financial strength metrics for Glaukos (GKOS) and Intuitive Surgical (ISRG)
MetricGKOSISRG
Current Ratio (MRQ)4.573.33
Debt / Equity (MRQ)0.15--
Net Debt / EBITDA---0.90

Dividends

Dividend Yield (TTM)

Neither Glaukos (GKOS) nor Intuitive Surgical (ISRG) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

GKOS

Health Care Equipment & Services industry group

0.00%

GKOS
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

ISRG

Health Care Equipment & Services industry group

0.00%

ISRG
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Glaukos (GKOS) vs. Intuitive Surgical (ISRG): A comparison of their dividend yield against the Health Care Equipment & Services industry group benchmark.

Dividend Payout Ratio (TTM)

Neither Glaukos (GKOS) nor Intuitive Surgical (ISRG) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

GKOS

Health Care Equipment & Services industry group

0.00%

GKOS
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

ISRG

Health Care Equipment & Services industry group

0.00%

ISRG
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Glaukos (GKOS) vs. Intuitive Surgical (ISRG): A comparison of their payout ratio against the Health Care Equipment & Services industry group benchmark.

Dividend Metrics

Dividend metrics for Glaukos (GKOS) and Intuitive Surgical (ISRG)
MetricGKOSISRG
Dividend Yield (TTM)0.00%0.00%
Dividend Payout Ratio (TTM)0.00%0.00%

Valuation

P/E Ratio (TTM)

An earnings multiple is available for just one side: Intuitive Surgical (ISRG) trades at 54.75 times trailing earnings, ranked against its peers, while Glaukos (GKOS) has no P/E ratio this period.

GKOS

Health Care Equipment & Services industry group

--

Max
80.41
Q3
47.62
Median
29.93
Q1
21.19
Min
4.21
GKOS
--

ISRG

Health Care Equipment & Services industry group

54.75

Max
80.41
ISRG
54.75
Q3
47.62
Median
29.93
Q1
21.19
Min
4.21
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Glaukos (GKOS) vs. Intuitive Surgical (ISRG): GKOS does not report P/E ratio, so it has no value marker; ISRG is benchmarked against the Health Care Equipment & Services industry group.

P/S Ratio (TTM)

Investors are paying well above the peer range per dollar of sales for both Glaukos (GKOS) at 19.24 and Intuitive Surgical (ISRG) at 13.82 — each P/S ratio clears its industry’s benchmark range.

GKOS

Health Care Equipment & Services industry group

19.24

GKOS
19.24
Max
8.80
Q3
4.32
Median
2.13
Q1
1.10
Min
0.03

ISRG

Health Care Equipment & Services industry group

13.82

ISRG
13.82
Max
8.80
Q3
4.32
Median
2.13
Q1
1.10
Min
0.03
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Glaukos (GKOS) vs. Intuitive Surgical (ISRG): A comparison of their P/S ratio against the Health Care Equipment & Services industry group benchmark.

P/B Ratio (MRQ)

Both look rich against book: Intuitive Surgical (ISRG) at 9.82 sits in the upper P/B ratio quartile, and Glaukos (GKOS) at 18.51 prices even higher, above its industry range.

GKOS

Health Care Equipment & Services industry group

18.51

GKOS
18.51
Max
11.68
Q3
6.12
Median
3.00
Q1
1.73
Min
-1.31

ISRG

Health Care Equipment & Services industry group

9.82

Max
11.68
ISRG
9.82
Q3
6.12
Median
3.00
Q1
1.73
Min
-1.31
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Glaukos (GKOS) vs. Intuitive Surgical (ISRG): A comparison of their P/B ratio against the Health Care Equipment & Services industry group benchmark.

Valuation Metrics

Valuation metrics for Glaukos (GKOS) and Intuitive Surgical (ISRG)
MetricGKOSISRG
P/E Ratio (TTM)--54.75
P/S Ratio (TTM)19.2413.82
P/B Ratio (MRQ)18.519.82
Free Cash Flow Yield (TTM)0.40%2.15%