GKOS vs. PEN: Glaukos vs. Penumbra Stock Comparison

November 11, 2026

How do Glaukos (GKOS) and Penumbra (PEN) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Glaukos (GKOS) and Penumbra (PEN) are both classified in the Health Care Equipment sub-industry within the broader Health Care Equipment & Supplies industry, placing them in the closest GICS peer bucket.

Company profile comparison for Glaukos (GKOS) and Penumbra (PEN)
Profile Item	GKOS	PEN
Name	Glaukos Corp.	Penumbra Inc.
Country/Region	United States	United States
GICS Sector	Health Care	Health Care
GICS Industry Group	Health Care Equipment & Services	Health Care Equipment & Services
GICS Industry	Health Care Equipment & Supplies	Health Care Equipment & Supplies
GICS Sub-Industry	Health Care Equipment	Health Care Equipment
Market Capitalization	13.28 billion USD	12.58 billion USD
Currency	USD	USD
Exchange	NYSE	NYSE
Listing Date	June 25, 2015	September 18, 2015
Security Type	Common Stock	Common Stock

Price Performance

Cumulative Growth

GKOS

PEN

GSPC

Glaukos (GKOS) vs. Penumbra (PEN), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Glaukos (GKOS) and Penumbra (PEN). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Glaukos (GKOS) and Penumbra (PEN). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Glaukos (GKOS) and Penumbra (PEN)
Metric	GKOS	PEN
Total Return (1Y)	179.91%	20.52%
Total Return (3Y, Annualized)	55.51%	20.38%
Total Return (5Y, Annualized)	35.14%	3.15%

Risk Profile

Drawdown History

GKOS

PEN

GSPC

Glaukos (GKOS) vs. Penumbra (PEN), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Glaukos (GKOS) and Penumbra (PEN). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Glaukos (GKOS) and Penumbra (PEN)
Metric	GKOS	PEN
Volatility (1Y, Annualized)	61.24%	19.78%
Beta (5Y)	0.68	0.68
Max Drawdown (5Y)	-53.68%	-59.60%
Avg. Volume (3M)	1.15M	348.64K

Risk-Adjusted Performance

Risk-Return Positioning

GKOS and PEN are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Glaukos (GKOS) and Penumbra (PEN)
Metric	GKOS	PEN
Sharpe Ratio (1Y)	2.87	0.82
Sortino Ratio (1Y)	5.93	1.56

Profitability

ROE (TTM)

Glaukos (GKOS) reports a negative ROE of -22.84%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile Penumbra (PEN) reports 10.67%, ranking against industry peers normally.

GKOS

Health Care Equipment & Services industry group

-22.84%

Max: 47.61%
Q3: 14.36%
Median: 5.45%
Q1: -10.67%
GKOS: -22.84%
Min: -47.01%

PEN

Health Care Equipment & Services industry group

10.67%

Max: 47.61%
Q3: 14.36%
PEN: 10.67%
Median: 5.45%
Q1: -10.67%
Min: -47.01%

Glaukos (GKOS) vs. Penumbra (PEN): A comparison of their ROE against the Health Care Equipment & Services industry group benchmark.

Net Margin (TTM)

Glaukos (GKOS) reports a negative net margin of -24.60%, usually indicating a net loss over the period. Meanwhile Penumbra (PEN) reports 10.06%, ranking against industry peers normally.

GKOS

Health Care Equipment & Services industry group

-24.60%

Max: 29.35%
Q3: 9.33%
Median: 2.18%
Q1: -6.29%
GKOS: -24.60%
Min: -28.46%

PEN

Health Care Equipment & Services industry group

10.06%

Max: 29.35%
PEN: 10.06%
Q3: 9.33%
Median: 2.18%
Q1: -6.29%
Min: -28.46%

Glaukos (GKOS) vs. Penumbra (PEN): A comparison of their net margin against the Health Care Equipment & Services industry group benchmark.

Operating Margin (TTM)

Both Glaukos (GKOS) at 0.39% and Penumbra (PEN) at 12.37% run core operations about as efficiently as their industries’ norm — neither stands out on operating profitability.

GKOS

Health Care Equipment & Services industry group

0.39%

Max: 35.43%
Q3: 14.14%
Median: 6.81%
GKOS: 0.39%
Q1: -0.28%
Min: -16.29%

PEN

Health Care Equipment & Services industry group

12.37%

Max: 35.43%
Q3: 14.14%
PEN: 12.37%
Median: 6.81%
Q1: -0.28%
Min: -16.29%

Glaukos (GKOS) vs. Penumbra (PEN): A comparison of their operating margin against the Health Care Equipment & Services industry group benchmark.

Profitability Metrics

Profitability metrics for Glaukos (GKOS) and Penumbra (PEN)
Metric	GKOS	PEN
ROE (TTM)	-22.84%	10.67%
ROA (TTM)	-3.90%	6.28%
Net Margin (TTM)	-24.60%	10.06%
Operating Margin (TTM)	0.39%	12.37%
Gross Margin (TTM)	81.13%	67.99%

Growth

Revenue Growth

Glaukos (GKOS) at 32.33% sits in the top revenue growth quartile, while Penumbra (PEN) at 17.50% is closer to the peer norm — faster top-line expansion for GKOS.

Glaukos (GKOS) vs. Penumbra (PEN): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: Penumbra (PEN) reports EPS growth of 1,155.56%, ranked against its industry; Glaukos (GKOS) has no EPS growth figure this period.

Glaukos (GKOS) vs. Penumbra (PEN): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Glaukos (GKOS) and Penumbra (PEN)
Metric	GKOS	PEN
Revenue Growth (YoY)	32.33%	17.50%
Revenue Growth (3Y CAGR)	21.51%	18.33%
EPS Growth (YoY)	--	1,155.56%
EPS Growth (3Y CAGR)	--	--

Financial Strength

Current Ratio (MRQ)

Both Glaukos (GKOS) at 4.57 and Penumbra (PEN) at 5.89 post current ratio above their industries’ typical mid-ranges — short-term liquidity appears comfortable, though unusually high readings can point to idle current assets.

GKOS

Health Care Equipment & Services industry group

4.57

Max: 7.59
GKOS: 4.57
Q3: 4.00
Median: 1.98
Q1: 1.37
Min: 0.30

PEN

Health Care Equipment & Services industry group

5.89

Max: 7.59
PEN: 5.89
Q3: 4.00
Median: 1.98
Q1: 1.37
Min: 0.30

Glaukos (GKOS) vs. Penumbra (PEN): A comparison of their current ratio against the Health Care Equipment & Services industry group benchmark.

Debt / Equity (MRQ)

Both Glaukos (GKOS) at 0.15 and Penumbra (PEN) at 0.13 keep leverage in the lower quartile of their industries, with less balance-sheet debt relative to equity than most peers.

GKOS

Health Care Equipment & Services industry group

0.15

Max: 1.88
Q3: 0.91
Median: 0.58
Q1: 0.16
GKOS: 0.15
Min: 0.00

PEN

Health Care Equipment & Services industry group

0.13

Max: 1.88
Q3: 0.91
Median: 0.58
Q1: 0.16
PEN: 0.13
Min: 0.00

Glaukos (GKOS) vs. Penumbra (PEN): A comparison of their debt-to-equity ratio against the Health Care Equipment & Services industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Glaukos (GKOS) and Penumbra (PEN)
Metric	GKOS	PEN
Current Ratio (MRQ)	4.57	5.89
Debt / Equity (MRQ)	0.15	0.13
Net Debt / EBITDA	--	-2.22

Dividends

Dividend Yield (TTM)

Neither Glaukos (GKOS) nor Penumbra (PEN) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

GKOS

Health Care Equipment & Services industry group

0.00%

GKOS: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

PEN

Health Care Equipment & Services industry group

0.00%

PEN: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Glaukos (GKOS) vs. Penumbra (PEN): A comparison of their dividend yield against the Health Care Equipment & Services industry group benchmark.

Dividend Payout Ratio (TTM)

Neither Glaukos (GKOS) nor Penumbra (PEN) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

GKOS

Health Care Equipment & Services industry group

0.00%

GKOS: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

PEN

Health Care Equipment & Services industry group

0.00%

PEN: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Glaukos (GKOS) vs. Penumbra (PEN): A comparison of their payout ratio against the Health Care Equipment & Services industry group benchmark.

Dividend Metrics

Dividend metrics for Glaukos (GKOS) and Penumbra (PEN)
Metric	GKOS	PEN
Dividend Yield (TTM)	0.00%	0.00%
Dividend Payout Ratio (TTM)	0.00%	0.00%

Valuation

P/E Ratio (TTM)

An earnings multiple is available for just one side: Penumbra (PEN) trades at 80.41 times trailing earnings, ranked against its peers, while Glaukos (GKOS) has no P/E ratio this period.

GKOS

Health Care Equipment & Services industry group

Max: 80.41
Q3: 47.62
Median: 29.93
Q1: 21.19
Min: 4.21
GKOS: --

PEN

Health Care Equipment & Services industry group

80.41

PEN: 80.41
Max: 80.41
Q3: 47.62
Median: 29.93
Q1: 21.19
Min: 4.21

Glaukos (GKOS) vs. Penumbra (PEN): GKOS does not report P/E ratio, so it has no value marker; PEN is benchmarked against the Health Care Equipment & Services industry group.

P/S Ratio (TTM)

Both look expensive on sales: Penumbra (PEN) at 8.06 sits in the upper P/S ratio quartile, and Glaukos (GKOS) at 19.24 prices even higher, above its industry range.

GKOS

Health Care Equipment & Services industry group

19.24

GKOS: 19.24
Max: 8.80
Q3: 4.32
Median: 2.13
Q1: 1.10
Min: 0.03

PEN

Health Care Equipment & Services industry group

8.06

Max: 8.80
PEN: 8.06
Q3: 4.32
Median: 2.13
Q1: 1.10
Min: 0.03

Glaukos (GKOS) vs. Penumbra (PEN): A comparison of their P/S ratio against the Health Care Equipment & Services industry group benchmark.

P/B Ratio (MRQ)

Both look rich against book: Penumbra (PEN) at 7.95 sits in the upper P/B ratio quartile, and Glaukos (GKOS) at 18.51 prices even higher, above its industry range.

GKOS

Health Care Equipment & Services industry group

18.51

GKOS: 18.51
Max: 11.68
Q3: 6.12
Median: 3.00
Q1: 1.73
Min: -1.31

PEN

Health Care Equipment & Services industry group

7.95

Max: 11.68
PEN: 7.95
Q3: 6.12
Median: 3.00
Q1: 1.73
Min: -1.31

Glaukos (GKOS) vs. Penumbra (PEN): A comparison of their P/B ratio against the Health Care Equipment & Services industry group benchmark.

Valuation Metrics

Valuation metrics for Glaukos (GKOS) and Penumbra (PEN)
Metric	GKOS	PEN
P/E Ratio (TTM)	--	80.41
P/S Ratio (TTM)	19.24	8.06
P/B Ratio (MRQ)	18.51	7.95
Free Cash Flow Yield (TTM)	0.40%	1.32%