GH vs. PEN: Guardant Health vs. Penumbra Stock Comparison
How do Guardant Health (GH) and Penumbra (PEN) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.
Company Profile
Guardant Health (GH) and Penumbra (PEN) both fall under the Health Care Equipment & Services industry group, but GH is classified in Health Care Providers & Services while PEN is classified in Health Care Equipment & Supplies.
| Profile Item | GH | PEN |
|---|---|---|
| Name | Guardant Health, Inc. | Penumbra Inc. |
| Country/Region | United States | United States |
| GICS Sector | Health Care | Health Care |
| GICS Industry Group | Health Care Equipment & Services | Health Care Equipment & Services |
| GICS Industry | Health Care Providers & Services | Health Care Equipment & Supplies |
| GICS Sub-Industry | Health Care Services | Health Care Equipment |
| Market Capitalization | 20.41 billion USD | 12.58 billion USD |
| Currency | USD | USD |
| Exchange | Nasdaq | NYSE |
| Listing Date | October 4, 2018 | September 18, 2015 |
| Security Type | Common Stock | Common Stock |
Price Performance
Cumulative Growth
Trailing Returns
Calendar-Year Returns
Performance Metrics
| Metric | GH | PEN |
|---|---|---|
| Total Return (1Y) | 66.53% | 20.52% |
| Total Return (3Y, Annualized) | 92.76% | 20.38% |
| Total Return (5Y, Annualized) | 8.36% | 3.15% |
Risk Profile
Drawdown History
Return Distribution
Risk Metrics
Guardant Health (GH) has an aggressive beta of 1.69, indicating higher sensitivity to broad-market moves, while Penumbra (PEN) is defensive at 0.68 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.
| Metric | GH | PEN |
|---|---|---|
| Volatility (1Y, Annualized) | 53.23% | 19.78% |
| Beta (5Y) | 1.69 | 0.68 |
| Max Drawdown (5Y) | -85.09% | -59.60% |
| Avg. Volume (3M) | 1.97M | 348.64K |
Risk-Adjusted Performance
Risk-Return Positioning
Risk-Adjusted Metrics
| Metric | GH | PEN |
|---|---|---|
| Sharpe Ratio (1Y) | 1.17 | 0.82 |
| Sortino Ratio (1Y) | 1.84 | 1.56 |
Profitability
ROE (TTM)
Capital efficiency shows on one side only: Penumbra (PEN) earns 10.67% on shareholders’ equity, ranked against its industry; Guardant Health (GH) has no ROE this period.
GH
Health Care Equipment & Services industry group
--
- Max
- 47.61%
- Q3
- 14.36%
- Median
- 5.45%
- Q1
- -10.67%
- Min
- -47.01%
- GH
- --
PEN
Health Care Equipment & Services industry group
10.67%
- Max
- 47.61%
- Q3
- 14.36%
- PEN
- 10.67%
- Median
- 5.45%
- Q1
- -10.67%
- Min
- -47.01%
Net Margin (TTM)
Guardant Health (GH) reports a negative net margin of -37.93%, usually indicating a net loss over the period. Meanwhile Penumbra (PEN) reports 10.06%, ranking against industry peers normally.
GH
Health Care Equipment & Services industry group
-37.93%
- Max
- 29.35%
- Q3
- 9.33%
- Median
- 2.18%
- Q1
- -6.29%
- Min
- -28.46%
- GH
- -37.93%
PEN
Health Care Equipment & Services industry group
10.06%
- Max
- 29.35%
- PEN
- 10.06%
- Q3
- 9.33%
- Median
- 2.18%
- Q1
- -6.29%
- Min
- -28.46%
Operating Margin (TTM)
Guardant Health (GH) reports a negative operating margin of -37.06%, usually indicating that operating costs exceeded revenue at the operating-income line. Meanwhile Penumbra (PEN) reports 12.37%, ranking against industry peers normally.
GH
Health Care Equipment & Services industry group
-37.06%
- Max
- 35.43%
- Q3
- 14.14%
- Median
- 6.81%
- Q1
- -0.28%
- Min
- -16.29%
- GH
- -37.06%
PEN
Health Care Equipment & Services industry group
12.37%
- Max
- 35.43%
- Q3
- 14.14%
- PEN
- 12.37%
- Median
- 6.81%
- Q1
- -0.28%
- Min
- -16.29%
Profitability Metrics
| Metric | GH | PEN |
|---|---|---|
| ROE (TTM) | -- | 10.67% |
| ROA (TTM) | -19.92% | 6.28% |
| Net Margin (TTM) | -37.93% | 10.06% |
| Operating Margin (TTM) | -37.06% | 12.37% |
| Gross Margin (TTM) | 65.19% | 67.99% |
Growth
Revenue Growth
Guardant Health (GH) at 32.88% sits in the top revenue growth quartile, while Penumbra (PEN) at 17.50% is closer to the peer norm — faster top-line expansion for GH.
EPS Growth
Only one side can be read here: Penumbra (PEN) reports EPS growth of 1,155.56%, ranked against its industry; Guardant Health (GH) has no EPS growth figure this period.
Growth Metrics
| Metric | GH | PEN |
|---|---|---|
| Revenue Growth (YoY) | 32.88% | 17.50% |
| Revenue Growth (3Y CAGR) | 29.75% | 18.33% |
| EPS Growth (YoY) | -- | 1,155.56% |
| EPS Growth (3Y CAGR) | -- | -- |
Financial Strength
Current Ratio (MRQ)
Guardant Health (GH) at 3.60 keeps current ratio within its industry’s typical mid-range, while Penumbra (PEN) at 5.89 sits above its industry’s typical mid-range — comfortable liquidity, though possibly with more idle current assets relative to peers.
GH
Health Care Equipment & Services industry group
3.60
- Max
- 7.59
- Q3
- 4.00
- GH
- 3.60
- Median
- 1.98
- Q1
- 1.37
- Min
- 0.30
PEN
Health Care Equipment & Services industry group
5.89
- Max
- 7.59
- PEN
- 5.89
- Q3
- 4.00
- Median
- 1.98
- Q1
- 1.37
- Min
- 0.30
Debt / Equity (MRQ)
Only one side’s leverage can be read here: Penumbra (PEN) carries debt-to-equity ratio of 0.13 against its industry range, while Guardant Health (GH) reports no figure this period.
GH
Health Care Equipment & Services industry group
--
- Max
- 1.88
- Q3
- 0.91
- Median
- 0.58
- Q1
- 0.16
- Min
- 0.00
- GH
- --
PEN
Health Care Equipment & Services industry group
0.13
- Max
- 1.88
- Q3
- 0.91
- Median
- 0.58
- Q1
- 0.16
- PEN
- 0.13
- Min
- 0.00
Financial Strength Metrics
| Metric | GH | PEN |
|---|---|---|
| Current Ratio (MRQ) | 3.60 | 5.89 |
| Debt / Equity (MRQ) | -- | 0.13 |
| Net Debt / EBITDA | -- | -2.22 |
Dividends
Dividend Yield (TTM)
Neither Guardant Health (GH) nor Penumbra (PEN) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.
GH
Health Care Equipment & Services industry group
0.00%
- GH
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
PEN
Health Care Equipment & Services industry group
0.00%
- PEN
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Payout Ratio (TTM)
Neither Guardant Health (GH) nor Penumbra (PEN) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.
GH
Health Care Equipment & Services industry group
0.00%
- GH
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
PEN
Health Care Equipment & Services industry group
0.00%
- PEN
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Metrics
| Metric | GH | PEN |
|---|---|---|
| Dividend Yield (TTM) | 0.00% | 0.00% |
| Dividend Payout Ratio (TTM) | 0.00% | 0.00% |
Valuation
P/E Ratio (TTM)
An earnings multiple is available for just one side: Penumbra (PEN) trades at 80.41 times trailing earnings, ranked against its peers, while Guardant Health (GH) has no P/E ratio this period.
GH
Health Care Equipment & Services industry group
--
- Max
- 80.41
- Q3
- 47.62
- Median
- 29.93
- Q1
- 21.19
- Min
- 4.21
- GH
- --
PEN
Health Care Equipment & Services industry group
80.41
- PEN
- 80.41
- Max
- 80.41
- Q3
- 47.62
- Median
- 29.93
- Q1
- 21.19
- Min
- 4.21
P/S Ratio (TTM)
Both look expensive on sales: Penumbra (PEN) at 8.06 sits in the upper P/S ratio quartile, and Guardant Health (GH) at 15.96 prices even higher, above its industry range.
GH
Health Care Equipment & Services industry group
15.96
- GH
- 15.96
- Max
- 8.80
- Q3
- 4.32
- Median
- 2.13
- Q1
- 1.10
- Min
- 0.03
PEN
Health Care Equipment & Services industry group
8.06
- Max
- 8.80
- PEN
- 8.06
- Q3
- 4.32
- Median
- 2.13
- Q1
- 1.10
- Min
- 0.03
P/B Ratio (MRQ)
Guardant Health (GH) reports a negative P/B ratio of -73.67, meaning negative book equity — the multiple itself is not meaningful for valuation. Meanwhile Penumbra (PEN) reports 7.95, ranking against industry peers normally.
GH
Health Care Equipment & Services industry group
-73.67
- Max
- 11.68
- Q3
- 6.12
- Median
- 3.00
- Q1
- 1.73
- Min
- -1.31
- GH
- -73.67
PEN
Health Care Equipment & Services industry group
7.95
- Max
- 11.68
- PEN
- 7.95
- Q3
- 6.12
- Median
- 3.00
- Q1
- 1.73
- Min
- -1.31
Valuation Metrics
| Metric | GH | PEN |
|---|---|---|
| P/E Ratio (TTM) | -- | 80.41 |
| P/S Ratio (TTM) | 15.96 | 8.06 |
| P/B Ratio (MRQ) | -73.67 | 7.95 |
| Free Cash Flow Yield (TTM) | -0.30% | 1.32% |