Guardant Health (GH) Stock Analysis

November 11, 2026

This is a peer-relative look at Guardant Health (GH): its performance, risk, profitability, growth, financial strength, dividend, and valuation are each measured against its Health Care Equipment & Services peers, so every number reads in context rather than in isolation.

Company Profile

Company profile fields for Guardant Health (GH)
Profile Item	GH
Name	Guardant Health, Inc.
Country/Region	United States
GICS Sector	Health Care
GICS Industry Group	Health Care Equipment & Services
GICS Industry	Health Care Providers & Services
GICS Sub-Industry	Health Care Services
Market Capitalization	20.41 billion USD
Currency	USD
Exchange	Nasdaq
Listing Date	October 4, 2018
Security Type	Common Stock

Price Performance

Cumulative Growth

GSPC

Guardant Health (GH) vs. S&P 500 (GSPC): Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Guardant Health (GH) and S&P 500 (GSPC). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Guardant Health (GH) and S&P 500 (GSPC). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Guardant Health (GH) metric values compared with Health Care Equipment & Services industry-group medians
Metric	Current stock: GH	Industry group median
Total Return (1Y)	66.53%	21.53%
Total Return (3Y, Annualized)	92.76%	9.81%
Total Return (5Y, Annualized)	8.36%	-2.76%

Risk Profile

Drawdown History

GSPC

Guardant Health (GH) vs. S&P 500 (GSPC): Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Guardant Health (GH) and S&P 500 (GSPC). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Guardant Health (GH) metric values compared with Health Care Equipment & Services industry-group medians
Metric	Current stock: GH	Industry group median
Volatility (1Y, Annualized)	53.23%	50.93%
Beta (5Y)	1.69	0.85
Max Drawdown (5Y)	-85.09%	-70.34%

Risk-Adjusted Performance

Risk-Return Positioning

Each dot is a stock plotted by 1-year volatility (risk) and 1-year return. GH is highlighted; the dashed line is the Capital Allocation Line from the risk-free rate through the industry median — dots above it are stronger on a risk-adjusted basis.

Risk-Adjusted Metrics

Guardant Health (GH) metric values compared with Health Care Equipment & Services industry-group medians
Metric	Current stock: GH	Industry group median
Sharpe Ratio (1Y)	1.17	0.34
Sortino Ratio (1Y)	1.84	0.54

Profitability

ROE (TTM)

No usable ROE is available for Guardant Health (GH) this period, so the shareholder-equity return read is skipped.

GH

Health Care Equipment & Services industry group

Group distribution

Max: 47.61%
Q3: 14.36%
Median: 5.45%
Q1: -10.67%
Min: -47.01%
GH: --

Largest peers

ISRG: 17.93%
SYK: 16.02%
UNH: 15.77%
MDT: 10.65%
ABT: 9.14%
GH: --
MCK: --

Guardant Health (GH) doesn’t report ROE this period; the box shows the Health Care Equipment & Services group’s distribution and the dots its largest members.

Net Margin (TTM)

Guardant Health (GH) has negative net margin of -37.93%. The trailing period ended in a net loss, so the bottom-line conversion read is a warning rather than a profitability strength.

GH

Health Care Equipment & Services industry group

-37.93%

Group distribution

Max: 29.35%
Q3: 9.33%
Median: 2.18%
Q1: -6.29%
Min: -28.46%
GH: -37.93%

Largest peers

ISRG: 25.54%
MDT: 13.93%
SYK: 13.78%
ABT: 9.75%
UNH: 3.53%
MCK: 1.12%
GH: -37.93%

Where Guardant Health (GH) stands on net margin within its Health Care Equipment & Services peer group — the box is the group’s distribution and the dots its largest members.

Operating Margin (TTM)

Guardant Health (GH) has negative operating margin of -37.06%. Core operations were loss-making before interest and taxes over the trailing period.

GH

Health Care Equipment & Services industry group

-37.06%

Group distribution

Max: 35.43%
Q3: 14.14%
Median: 6.81%
Q1: -0.28%
Min: -16.29%
GH: -37.06%

Largest peers

ISRG: 33.29%
SYK: 22.96%
MDT: 19.33%
ABT: 11.66%
UNH: 5.82%
MCK: 1.48%
GH: -37.06%

Where Guardant Health (GH) stands on operating margin within its Health Care Equipment & Services peer group — the box is the group’s distribution and the dots its largest members.

Profitability Metrics

Guardant Health (GH) metric values compared with Health Care Equipment & Services industry-group medians
Metric	Current stock: GH	Industry group median
ROE (TTM)	--	5.45%
ROA (TTM)	-19.92%	3.17%
Net Margin (TTM)	-37.93%	2.18%
Operating Margin (TTM)	-37.06%	6.81%
Gross Margin (TTM)	65.19%	55.21%

Growth

Revenue Growth

Guardant Health (GH) grew revenue 32.88%, in the upper peer quartile. The top line is expanding faster than at most industry peers, which points to share gains or stronger pricing.

Guardant Health (GH): Revenue Growth across different time periods, set against Health Care Equipment & Services industry-group medians.

EPS Growth

No usable EPS growth is available for Guardant Health (GH) this period, so the earnings-momentum read is skipped.

Guardant Health (GH) doesn't report EPS Growth this period; the bars show the Health Care Equipment & Services industry-group medians on their own.

Growth Metrics

Guardant Health (GH) metric values compared with Health Care Equipment & Services industry-group medians
Metric	Current stock: GH	Industry group median
Revenue Growth (YoY)	32.88%	11.55%
Revenue Growth (3Y CAGR)	29.75%	10.83%
EPS Growth (YoY)	--	4.88%
EPS Growth (3Y CAGR)	--	14.59%

Financial Strength

Current Ratio (MRQ)

Guardant Health (GH) has current ratio of 3.60, in the healthier middle range for its industry. The short-term asset cushion looks balanced relative to peers rather than stretched thin.

GH

Health Care Equipment & Services industry group

3.60

Group distribution

Max: 7.59
Q3: 4.00
GH: 3.60
Median: 1.98
Q1: 1.37
Min: 0.30

Largest peers

GH: 3.60
ISRG: 3.33
SYK: 2.18
MDT: 2.07
ABT: 1.46
MCK: 0.90
UNH: 0.74

Where Guardant Health (GH) stands on current ratio within its Health Care Equipment & Services peer group — the box is the group’s distribution and the dots its largest members.

Debt / Equity (MRQ)

No usable debt-to-equity ratio is available for Guardant Health (GH) this period, so the balance-sheet leverage read is skipped.

GH

Health Care Equipment & Services industry group

Group distribution

Max: 1.88
Q3: 0.91
Median: 0.58
Q1: 0.16
Min: 0.00
GH: --

Largest peers

UNH: 0.70
SYK: 0.66
ABT: 0.61
MDT: 0.55
GH: --
ISRG: --
MCK: --

Guardant Health (GH) doesn’t report debt-to-equity ratio this period; the box shows the Health Care Equipment & Services group’s distribution and the dots its largest members.

Financial Strength Metrics

Guardant Health (GH) metric values compared with Health Care Equipment & Services industry-group medians
Metric	Current stock: GH	Industry group median
Current Ratio (MRQ)	3.60	1.98
Debt / Equity (MRQ)	--	0.58
Net Debt / EBITDA	--	2.04

Dividends

Dividend Yield (TTM)

Guardant Health (GH) pays no dividend, leaving dividend yield at 0.00% this period. Shareholders may still receive value through reinvestment or buybacks, but there is no dividend income to compare here.

GH

Health Care Equipment & Services industry group

0.00%

Group distribution

GH: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Largest peers

MDT: 2.72%
UNH: 2.29%
ABT: 2.22%
SYK: 1.05%
MCK: 0.32%
GH: 0.00%
ISRG: 0.00%

Where Guardant Health (GH) stands on dividend yield within its Health Care Equipment & Services peer group — the box is the group’s distribution and the dots its largest members.

Dividend Payout Ratio (TTM)

Guardant Health (GH) paid no earnings out as dividends this period, leaving payout ratio at 0.00%. There is no dividend payout to size against earnings.

GH

Health Care Equipment & Services industry group

0.00%

Group distribution

GH: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Largest peers

ABT: 92.54%
MDT: 70.02%
UNH: 51.71%
SYK: 37.49%
MCK: 8.77%
GH: 0.00%
ISRG: 0.00%

Where Guardant Health (GH) stands on payout ratio within its Health Care Equipment & Services peer group — the box is the group’s distribution and the dots its largest members.

Dividend Metrics

Guardant Health (GH) metric values compared with Health Care Equipment & Services industry-group medians
Metric	Current stock: GH	Industry group median
Dividend Yield (TTM)	0.00%	0.00%
Dividend Payout Ratio (TTM)	0.00%	0.00%

Valuation

P/E Ratio (TTM)

No usable P/E ratio is available for Guardant Health (GH) this period, so the trailing-earnings valuation read is skipped.

GH

Health Care Equipment & Services industry group

Group distribution

Max: 80.41
Q3: 47.62
Median: 29.93
Q1: 21.19
Min: 4.21
GH: --

Largest peers

ISRG: 54.75
ABT: 41.02
SYK: 34.70
MCK: 27.36
MDT: 25.01
UNH: 22.50
GH: --

Guardant Health (GH) doesn’t report P/E ratio this period; the box shows the Health Care Equipment & Services group’s distribution and the dots its largest members.

P/S Ratio (TTM)

Guardant Health (GH) trades at 15.96 on P/S ratio, above the industry benchmark range. The stock is being valued at an unusually rich price per dollar of trailing revenue.

GH

Health Care Equipment & Services industry group

15.96

Group distribution

GH: 15.96
Max: 8.80
Q3: 4.32
Median: 2.13
Q1: 1.10
Min: 0.03

Largest peers

GH: 15.96
ISRG: 13.82
SYK: 4.72
ABT: 3.95
MDT: 3.47
UNH: 0.78
MCK: 0.29

Where Guardant Health (GH) stands on P/S ratio within its Health Care Equipment & Services peer group — the box is the group’s distribution and the dots its largest members.

P/B Ratio (MRQ)

Guardant Health (GH) has negative P/B ratio of -73.67, which means reported book equity is negative. Price-to-book breaks down in this situation and should not be used as a valuation signal.

GH

Health Care Equipment & Services industry group

-73.67

Group distribution

Max: 11.68
Q3: 6.12
Median: 3.00
Q1: 1.73
Min: -1.31
GH: -73.67

Largest peers

ISRG: 9.82
SYK: 5.29
ABT: 3.73
UNH: 3.60
MDT: 2.59
MCK: -30.85
GH: -73.67

Where Guardant Health (GH) stands on P/B ratio within its Health Care Equipment & Services peer group — the box is the group’s distribution and the dots its largest members.

Valuation Metrics

Guardant Health (GH) metric values compared with Health Care Equipment & Services industry-group medians
Metric	Current stock: GH	Industry group median
P/E Ratio (TTM)	--	29.93
P/S Ratio (TTM)	15.96	2.13
P/B Ratio (MRQ)	-73.67	3.00
Free Cash Flow Yield (TTM)	-0.30%	3.50%