GH vs. MCK: Guardant Health vs. McKesson Stock Comparison
How do Guardant Health (GH) and McKesson (MCK) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.
Company Profile
Guardant Health (GH) and McKesson (MCK) both belong to the Health Care Providers & Services industry, though GH is classified under Health Care Services while MCK falls under Health Care Distributors.
| Profile Item | GH | MCK |
|---|---|---|
| Name | Guardant Health, Inc. | McKesson Corporation |
| Country/Region | United States | United States |
| GICS Sector | Health Care | Health Care |
| GICS Industry Group | Health Care Equipment & Services | Health Care Equipment & Services |
| GICS Industry | Health Care Providers & Services | Health Care Providers & Services |
| GICS Sub-Industry | Health Care Services | Health Care Distributors |
| Market Capitalization | 20.41 billion USD | 122.48 billion USD |
| Currency | USD | USD |
| Exchange | Nasdaq | NYSE |
| Listing Date | October 4, 2018 | November 10, 1994 |
| Security Type | Common Stock | Common Stock |
Price Performance
Cumulative Growth
Trailing Returns
Calendar-Year Returns
Performance Metrics
| Metric | GH | MCK |
|---|---|---|
| Total Return (1Y) | 66.53% | 25.40% |
| Total Return (3Y, Annualized) | 92.76% | 32.67% |
| Total Return (5Y, Annualized) | 8.36% | 37.84% |
Risk Profile
Drawdown History
Return Distribution
Risk Metrics
Guardant Health (GH) has an aggressive beta of 1.69, indicating higher sensitivity to broad-market moves, while McKesson (MCK) is defensive at 0.26 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.
| Metric | GH | MCK |
|---|---|---|
| Volatility (1Y, Annualized) | 53.23% | 31.71% |
| Beta (5Y) | 1.69 | 0.26 |
| Max Drawdown (5Y) | -85.09% | -27.17% |
| Avg. Volume (3M) | 1.97M | 822.69K |
Risk-Adjusted Performance
Risk-Return Positioning
Risk-Adjusted Metrics
| Metric | GH | MCK |
|---|---|---|
| Sharpe Ratio (1Y) | 1.17 | 0.67 |
| Sortino Ratio (1Y) | 1.84 | 1.15 |
Profitability
ROE (TTM)
Neither Guardant Health (GH) nor McKesson (MCK) reports a ROE value for this period, so a direct comparison isn’t possible.
GH
Health Care Equipment & Services industry group
--
- Max
- 47.61%
- Q3
- 14.36%
- Median
- 5.45%
- Q1
- -10.67%
- Min
- -47.01%
- GH
- --
MCK
Health Care Equipment & Services industry group
--
- Max
- 47.61%
- Q3
- 14.36%
- Median
- 5.45%
- Q1
- -10.67%
- Min
- -47.01%
- MCK
- --
Net Margin (TTM)
Guardant Health (GH) reports a negative net margin of -37.93%, usually indicating a net loss over the period. Meanwhile McKesson (MCK) reports 1.12%, ranking against industry peers normally.
GH
Health Care Equipment & Services industry group
-37.93%
- Max
- 29.35%
- Q3
- 9.33%
- Median
- 2.18%
- Q1
- -6.29%
- Min
- -28.46%
- GH
- -37.93%
MCK
Health Care Equipment & Services industry group
1.12%
- Max
- 29.35%
- Q3
- 9.33%
- Median
- 2.18%
- MCK
- 1.12%
- Q1
- -6.29%
- Min
- -28.46%
Operating Margin (TTM)
Guardant Health (GH) reports a negative operating margin of -37.06%, usually indicating that operating costs exceeded revenue at the operating-income line. Meanwhile McKesson (MCK) reports 1.48%, ranking against industry peers normally.
GH
Health Care Equipment & Services industry group
-37.06%
- Max
- 35.43%
- Q3
- 14.14%
- Median
- 6.81%
- Q1
- -0.28%
- Min
- -16.29%
- GH
- -37.06%
MCK
Health Care Equipment & Services industry group
1.48%
- Max
- 35.43%
- Q3
- 14.14%
- Median
- 6.81%
- MCK
- 1.48%
- Q1
- -0.28%
- Min
- -16.29%
Profitability Metrics
| Metric | GH | MCK |
|---|---|---|
| ROE (TTM) | -- | -- |
| ROA (TTM) | -19.92% | 4.72% |
| Net Margin (TTM) | -37.93% | 1.12% |
| Operating Margin (TTM) | -37.06% | 1.48% |
| Gross Margin (TTM) | 65.19% | 3.65% |
Growth
Revenue Growth
Guardant Health (GH) at 32.88% sits in the top revenue growth quartile, while McKesson (MCK) at 12.36% is closer to the peer norm — faster top-line expansion for GH.
EPS Growth
Only one side can be read here: McKesson (MCK) reports EPS growth of 49.22%, ranked against its industry; Guardant Health (GH) has no EPS growth figure this period.
Growth Metrics
| Metric | GH | MCK |
|---|---|---|
| Revenue Growth (YoY) | 32.88% | 12.36% |
| Revenue Growth (3Y CAGR) | 29.75% | 13.39% |
| EPS Growth (YoY) | -- | 49.22% |
| EPS Growth (3Y CAGR) | -- | 15.31% |
Financial Strength
Current Ratio (MRQ)
Guardant Health (GH) at 3.60 keeps current ratio within its industry’s typical mid-range, while McKesson (MCK) at 0.90 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for MCK.
GH
Health Care Equipment & Services industry group
3.60
- Max
- 7.59
- Q3
- 4.00
- GH
- 3.60
- Median
- 1.98
- Q1
- 1.37
- Min
- 0.30
MCK
Health Care Equipment & Services industry group
0.90
- Max
- 7.59
- Q3
- 4.00
- Median
- 1.98
- Q1
- 1.37
- MCK
- 0.90
- Min
- 0.30
Debt / Equity (MRQ)
Neither Guardant Health (GH) nor McKesson (MCK) reports a debt-to-equity ratio value for this period, so a direct comparison isn’t possible.
GH
Health Care Equipment & Services industry group
--
- Max
- 1.88
- Q3
- 0.91
- Median
- 0.58
- Q1
- 0.16
- Min
- 0.00
- GH
- --
MCK
Health Care Equipment & Services industry group
--
- Max
- 1.88
- Q3
- 0.91
- Median
- 0.58
- Q1
- 0.16
- Min
- 0.00
- MCK
- --
Financial Strength Metrics
| Metric | GH | MCK |
|---|---|---|
| Current Ratio (MRQ) | 3.60 | 0.90 |
| Debt / Equity (MRQ) | -- | -- |
| Net Debt / EBITDA | -- | 0.64 |
Dividends
Dividend Yield (TTM)
Guardant Health (GH) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile McKesson (MCK) reports a yield of 0.32%, ranking against industry peers normally.
GH
Health Care Equipment & Services industry group
0.00%
- GH
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
MCK
Health Care Equipment & Services industry group
0.32%
- MCK
- 0.32%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Payout Ratio (TTM)
Guardant Health (GH) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile McKesson (MCK) reports a payout of 8.77%, ranking against industry peers normally.
GH
Health Care Equipment & Services industry group
0.00%
- GH
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
MCK
Health Care Equipment & Services industry group
8.77%
- MCK
- 8.77%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Metrics
| Metric | GH | MCK |
|---|---|---|
| Dividend Yield (TTM) | 0.00% | 0.32% |
| Dividend Payout Ratio (TTM) | 0.00% | 8.77% |
Valuation
P/E Ratio (TTM)
An earnings multiple is available for just one side: McKesson (MCK) trades at 27.36 times trailing earnings, ranked against its peers, while Guardant Health (GH) has no P/E ratio this period.
GH
Health Care Equipment & Services industry group
--
- Max
- 80.41
- Q3
- 47.62
- Median
- 29.93
- Q1
- 21.19
- Min
- 4.21
- GH
- --
MCK
Health Care Equipment & Services industry group
27.36
- Max
- 80.41
- Q3
- 47.62
- Median
- 29.93
- MCK
- 27.36
- Q1
- 21.19
- Min
- 4.21
P/S Ratio (TTM)
McKesson (MCK) at 0.29 sits in the cheaper P/S ratio quartile while Guardant Health (GH) at 15.96 prices above its industry range — a wide gap in sales valuation between them.
GH
Health Care Equipment & Services industry group
15.96
- GH
- 15.96
- Max
- 8.80
- Q3
- 4.32
- Median
- 2.13
- Q1
- 1.10
- Min
- 0.03
MCK
Health Care Equipment & Services industry group
0.29
- Max
- 8.80
- Q3
- 4.32
- Median
- 2.13
- Q1
- 1.10
- MCK
- 0.29
- Min
- 0.03
P/B Ratio (MRQ)
Both Guardant Health (GH) at -73.67 and McKesson (MCK) at -30.85 report negative P/B ratio values, meaning both companies have negative book equity — neither multiple is meaningful for valuation.
GH
Health Care Equipment & Services industry group
-73.67
- Max
- 11.68
- Q3
- 6.12
- Median
- 3.00
- Q1
- 1.73
- Min
- -1.31
- GH
- -73.67
MCK
Health Care Equipment & Services industry group
-30.85
- Max
- 11.68
- Q3
- 6.12
- Median
- 3.00
- Q1
- 1.73
- Min
- -1.31
- MCK
- -30.85
Valuation Metrics
| Metric | GH | MCK |
|---|---|---|
| P/E Ratio (TTM) | -- | 27.36 |
| P/S Ratio (TTM) | 15.96 | 0.29 |
| P/B Ratio (MRQ) | -73.67 | -30.85 |
| Free Cash Flow Yield (TTM) | -0.30% | 6.04% |