GH vs. GKOS: Guardant Health vs. Glaukos Stock Comparison
How do Guardant Health (GH) and Glaukos (GKOS) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.
Company Profile
Guardant Health (GH) and Glaukos (GKOS) both fall under the Health Care Equipment & Services industry group, but GH is classified in Health Care Providers & Services while GKOS is classified in Health Care Equipment & Supplies.
| Profile Item | GH | GKOS |
|---|---|---|
| Name | Guardant Health, Inc. | Glaukos Corp. |
| Country/Region | United States | United States |
| GICS Sector | Health Care | Health Care |
| GICS Industry Group | Health Care Equipment & Services | Health Care Equipment & Services |
| GICS Industry | Health Care Providers & Services | Health Care Equipment & Supplies |
| GICS Sub-Industry | Health Care Services | Health Care Equipment |
| Market Capitalization | 20.41 billion USD | 13.28 billion USD |
| Currency | USD | USD |
| Exchange | Nasdaq | NYSE |
| Listing Date | October 4, 2018 | June 25, 2015 |
| Security Type | Common Stock | Common Stock |
Price Performance
Cumulative Growth
Trailing Returns
Calendar-Year Returns
Performance Metrics
| Metric | GH | GKOS |
|---|---|---|
| Total Return (1Y) | 66.53% | 179.91% |
| Total Return (3Y, Annualized) | 92.76% | 55.51% |
| Total Return (5Y, Annualized) | 8.36% | 35.14% |
Risk Profile
Drawdown History
Return Distribution
Risk Metrics
Guardant Health (GH) has an aggressive beta of 1.69, indicating higher sensitivity to broad-market moves, while Glaukos (GKOS) is defensive at 0.68 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.
| Metric | GH | GKOS |
|---|---|---|
| Volatility (1Y, Annualized) | 53.23% | 61.24% |
| Beta (5Y) | 1.69 | 0.68 |
| Max Drawdown (5Y) | -85.09% | -53.68% |
| Avg. Volume (3M) | 1.97M | 1.15M |
Risk-Adjusted Performance
Risk-Return Positioning
Risk-Adjusted Metrics
| Metric | GH | GKOS |
|---|---|---|
| Sharpe Ratio (1Y) | 1.17 | 2.87 |
| Sortino Ratio (1Y) | 1.84 | 5.93 |
Profitability
ROE (TTM)
Guardant Health (GH) has no ROE value reported for this period; Glaukos (GKOS) reports a negative figure of -22.84%, which needs context because negative ROE can reflect losses or negative shareholders’ equity.
GH
Health Care Equipment & Services industry group
--
- Max
- 47.61%
- Q3
- 14.36%
- Median
- 5.45%
- Q1
- -10.67%
- Min
- -47.01%
- GH
- --
GKOS
Health Care Equipment & Services industry group
-22.84%
- Max
- 47.61%
- Q3
- 14.36%
- Median
- 5.45%
- Q1
- -10.67%
- GKOS
- -22.84%
- Min
- -47.01%
Net Margin (TTM)
Both Guardant Health (GH) at -37.93% and Glaukos (GKOS) at -24.60% report negative net margin values, usually indicating net losses over the period.
GH
Health Care Equipment & Services industry group
-37.93%
- Max
- 29.35%
- Q3
- 9.33%
- Median
- 2.18%
- Q1
- -6.29%
- Min
- -28.46%
- GH
- -37.93%
GKOS
Health Care Equipment & Services industry group
-24.60%
- Max
- 29.35%
- Q3
- 9.33%
- Median
- 2.18%
- Q1
- -6.29%
- GKOS
- -24.60%
- Min
- -28.46%
Operating Margin (TTM)
Guardant Health (GH) reports a negative operating margin of -37.06%, usually indicating that operating costs exceeded revenue at the operating-income line. Meanwhile Glaukos (GKOS) reports 0.39%, ranking against industry peers normally.
GH
Health Care Equipment & Services industry group
-37.06%
- Max
- 35.43%
- Q3
- 14.14%
- Median
- 6.81%
- Q1
- -0.28%
- Min
- -16.29%
- GH
- -37.06%
GKOS
Health Care Equipment & Services industry group
0.39%
- Max
- 35.43%
- Q3
- 14.14%
- Median
- 6.81%
- GKOS
- 0.39%
- Q1
- -0.28%
- Min
- -16.29%
Profitability Metrics
| Metric | GH | GKOS |
|---|---|---|
| ROE (TTM) | -- | -22.84% |
| ROA (TTM) | -19.92% | -3.90% |
| Net Margin (TTM) | -37.93% | -24.60% |
| Operating Margin (TTM) | -37.06% | 0.39% |
| Gross Margin (TTM) | 65.19% | 81.13% |
Growth
Revenue Growth
Both Guardant Health (GH) at 32.88% and Glaukos (GKOS) at 32.33% sit in the top peer quartile for revenue growth, so each is growing its top line faster than typical industry peers.
EPS Growth
Neither Guardant Health (GH) nor Glaukos (GKOS) reports a EPS growth value for this period, so a direct comparison isn't possible.
Growth Metrics
| Metric | GH | GKOS |
|---|---|---|
| Revenue Growth (YoY) | 32.88% | 32.33% |
| Revenue Growth (3Y CAGR) | 29.75% | 21.51% |
| EPS Growth (YoY) | -- | -- |
| EPS Growth (3Y CAGR) | -- | -- |
Financial Strength
Current Ratio (MRQ)
Guardant Health (GH) at 3.60 keeps current ratio within its industry’s typical mid-range, while Glaukos (GKOS) at 4.57 sits above its industry’s typical mid-range — comfortable liquidity, though possibly with more idle current assets relative to peers.
GH
Health Care Equipment & Services industry group
3.60
- Max
- 7.59
- Q3
- 4.00
- GH
- 3.60
- Median
- 1.98
- Q1
- 1.37
- Min
- 0.30
GKOS
Health Care Equipment & Services industry group
4.57
- Max
- 7.59
- GKOS
- 4.57
- Q3
- 4.00
- Median
- 1.98
- Q1
- 1.37
- Min
- 0.30
Debt / Equity (MRQ)
Only one side’s leverage can be read here: Glaukos (GKOS) carries debt-to-equity ratio of 0.15 against its industry range, while Guardant Health (GH) reports no figure this period.
GH
Health Care Equipment & Services industry group
--
- Max
- 1.88
- Q3
- 0.91
- Median
- 0.58
- Q1
- 0.16
- Min
- 0.00
- GH
- --
GKOS
Health Care Equipment & Services industry group
0.15
- Max
- 1.88
- Q3
- 0.91
- Median
- 0.58
- Q1
- 0.16
- GKOS
- 0.15
- Min
- 0.00
Financial Strength Metrics
| Metric | GH | GKOS |
|---|---|---|
| Current Ratio (MRQ) | 3.60 | 4.57 |
| Debt / Equity (MRQ) | -- | 0.15 |
| Net Debt / EBITDA | -- | -- |
Dividends
Dividend Yield (TTM)
Neither Guardant Health (GH) nor Glaukos (GKOS) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.
GH
Health Care Equipment & Services industry group
0.00%
- GH
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
GKOS
Health Care Equipment & Services industry group
0.00%
- GKOS
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Payout Ratio (TTM)
Neither Guardant Health (GH) nor Glaukos (GKOS) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.
GH
Health Care Equipment & Services industry group
0.00%
- GH
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
GKOS
Health Care Equipment & Services industry group
0.00%
- GKOS
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Metrics
| Metric | GH | GKOS |
|---|---|---|
| Dividend Yield (TTM) | 0.00% | 0.00% |
| Dividend Payout Ratio (TTM) | 0.00% | 0.00% |
Valuation
P/E Ratio (TTM)
Neither Guardant Health (GH) nor Glaukos (GKOS) reports a P/E ratio value for this period, so a direct comparison isn’t possible.
GH
Health Care Equipment & Services industry group
--
- Max
- 80.41
- Q3
- 47.62
- Median
- 29.93
- Q1
- 21.19
- Min
- 4.21
- GH
- --
GKOS
Health Care Equipment & Services industry group
--
- Max
- 80.41
- Q3
- 47.62
- Median
- 29.93
- Q1
- 21.19
- Min
- 4.21
- GKOS
- --
P/S Ratio (TTM)
Investors are paying well above the peer range per dollar of sales for both Guardant Health (GH) at 15.96 and Glaukos (GKOS) at 19.24 — each P/S ratio clears its industry’s benchmark range.
GH
Health Care Equipment & Services industry group
15.96
- GH
- 15.96
- Max
- 8.80
- Q3
- 4.32
- Median
- 2.13
- Q1
- 1.10
- Min
- 0.03
GKOS
Health Care Equipment & Services industry group
19.24
- GKOS
- 19.24
- Max
- 8.80
- Q3
- 4.32
- Median
- 2.13
- Q1
- 1.10
- Min
- 0.03
P/B Ratio (MRQ)
Guardant Health (GH) reports a negative P/B ratio of -73.67, meaning negative book equity — the multiple itself is not meaningful for valuation. Meanwhile Glaukos (GKOS) reports 18.51, ranking against industry peers normally.
GH
Health Care Equipment & Services industry group
-73.67
- Max
- 11.68
- Q3
- 6.12
- Median
- 3.00
- Q1
- 1.73
- Min
- -1.31
- GH
- -73.67
GKOS
Health Care Equipment & Services industry group
18.51
- GKOS
- 18.51
- Max
- 11.68
- Q3
- 6.12
- Median
- 3.00
- Q1
- 1.73
- Min
- -1.31
Valuation Metrics
| Metric | GH | GKOS |
|---|---|---|
| P/E Ratio (TTM) | -- | -- |
| P/S Ratio (TTM) | 15.96 | 19.24 |
| P/B Ratio (MRQ) | -73.67 | 18.51 |
| Free Cash Flow Yield (TTM) | -0.30% | 0.40% |