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BIIB vs. TEM: Biogen vs. Tempus AI Stock Comparison

How do Biogen (BIIB) and Tempus AI (TEM) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Biogen (BIIB) and Tempus AI (TEM) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but BIIB is classified in Biotechnology while TEM is classified in Life Sciences Tools & Services.

Biogen (BIIB) carries decades of public-market history since September 17, 1991, while Tempus AI (TEM) listed on June 14, 2024 — long-window comparisons have far more historical data on the BIIB side.

Company profile comparison for Biogen (BIIB) and Tempus AI (TEM)
Profile ItemBIIBTEM
NameBiogen Inc.Tempus AI Inc Class A Common Stock
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyLife Sciences Tools & Services
GICS Sub-IndustryBiotechnologyLife Sciences Tools & Services
Market Capitalization36.71 billion USD13.87 billion USD
CurrencyUSDUSD
ExchangeNasdaqNasdaq
Listing DateSeptember 17, 1991June 14, 2024
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

BIIB
TEM
GSPC
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Biogen (BIIB) vs. Tempus AI (TEM), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Biogen (BIIB) and Tempus AI (TEM). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Biogen (BIIB) and Tempus AI (TEM). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Biogen (BIIB) and Tempus AI (TEM)
MetricBIIBTEM
Total Return (1Y)65.44%16.25%
Total Return (3Y, Annualized)4.62%--
Total Return (5Y, Annualized)-0.96%--

Risk Profile

Drawdown History

BIIB
TEM
GSPC
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Biogen (BIIB) vs. Tempus AI (TEM), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Biogen (BIIB) and Tempus AI (TEM). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Tempus AI (TEM) has a highly aggressive beta of 3.34, indicating much higher sensitivity to broad-market moves, while Biogen (BIIB) is defensive at 0.08 and tends to be less market-sensitive — a wide gap in beta profiles.

Risk profile metrics for Biogen (BIIB) and Tempus AI (TEM)
MetricBIIBTEM
Volatility (1Y, Annualized)34.58%76.08%
Beta (5Y)0.083.34
Max Drawdown (5Y)-64.35%-59.76%
Avg. Volume (3M)1.05M7.20M

Risk-Adjusted Performance

Risk-Return Positioning

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BIIB and TEM are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Biogen (BIIB) and Tempus AI (TEM)
MetricBIIBTEM
Sharpe Ratio (1Y)1.770.16
Sortino Ratio (1Y)2.770.26

Profitability

ROE (TTM)

Tempus AI (TEM) reports a negative ROE of -37.55%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile Biogen (BIIB) reports 1.87%, ranking against industry peers normally.

BIIB

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.87%

Max
109.18%
Q3
6.23%
BIIB
1.87%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

-37.55%

Max
109.18%
Q3
6.23%
Median
-26.66%
TEM
-37.55%
Q1
-64.05%
Min
-167.77%
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Biogen (BIIB) vs. Tempus AI (TEM): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Tempus AI (TEM) reports a negative net margin of -12.54%, usually indicating a net loss over the period. Meanwhile Biogen (BIIB) reports 3.38%, ranking against industry peers normally.

BIIB

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.38%

Max
18.05%
Q3
4.78%
BIIB
3.38%
Median
0.00%
Q1
-4.14%
Min
-17.05%

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

-12.54%

Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
TEM
-12.54%
Min
-17.05%
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Biogen (BIIB) vs. Tempus AI (TEM): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Tempus AI (TEM) reports a negative operating margin of -13.82%, usually indicating that operating costs exceeded revenue at the operating-income line. Meanwhile Biogen (BIIB) reports 24.12%, ranking against industry peers normally.

BIIB

Pharmaceuticals, Biotechnology & Life Sciences industry group

24.12%

Max
83.12%
BIIB
24.12%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

-13.82%

Max
83.12%
Q3
14.77%
Median
0.00%
TEM
-13.82%
Q1
-78.82%
Min
-207.40%
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Biogen (BIIB) vs. Tempus AI (TEM): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Biogen (BIIB) and Tempus AI (TEM)
MetricBIIBTEM
ROE (TTM)1.87%-37.55%
ROA (TTM)4.94%-7.36%
Net Margin (TTM)3.38%-12.54%
Operating Margin (TTM)24.12%-13.82%
Gross Margin (TTM)75.77%64.46%

Growth

Revenue Growth

Tempus AI (TEM) at 83.41% sits in the top revenue growth quartile, while Biogen (BIIB) at 2.22% is closer to the peer norm — faster top-line expansion for TEM.

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Biogen (BIIB) vs. Tempus AI (TEM): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: Biogen (BIIB) reports EPS growth of -21.38%, ranked against its industry; Tempus AI (TEM) has no EPS growth figure this period.

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Biogen (BIIB) vs. Tempus AI (TEM): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Biogen (BIIB) and Tempus AI (TEM)
MetricBIIBTEM
Revenue Growth (YoY)2.22%83.41%
Revenue Growth (3Y CAGR)-0.94%58.29%
EPS Growth (YoY)-21.38%--
EPS Growth (3Y CAGR)-25.04%--

Financial Strength

Current Ratio (MRQ)

Tempus AI (TEM) at 2.61 keeps current ratio within its industry’s typical mid-range, while Biogen (BIIB) at 1.95 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for BIIB.

BIIB

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.95

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
BIIB
1.95
Min
0.10

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.61

Max
25.13
Q3
12.13
Median
5.52
TEM
2.61
Q1
2.47
Min
0.10
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Biogen (BIIB) vs. Tempus AI (TEM): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Biogen (BIIB) at 0.41 is near its industry mid-range for debt-to-equity ratio, while Tempus AI (TEM) at 2.86 sits above its benchmark range, pointing to a heavier debt load relative to equity.

BIIB

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.41

Max
1.42
Q3
0.65
BIIB
0.41
Median
0.15
Q1
0.02
Min
0.00

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.86

TEM
2.86
Max
1.42
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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Biogen (BIIB) vs. Tempus AI (TEM): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Biogen (BIIB) and Tempus AI (TEM)
MetricBIIBTEM
Current Ratio (MRQ)1.952.61
Debt / Equity (MRQ)0.412.86
Net Debt / EBITDA1.97--

Dividends

Dividend Yield (TTM)

Neither Biogen (BIIB) nor Tempus AI (TEM) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

BIIB

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

BIIB
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

TEM
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Biogen (BIIB) vs. Tempus AI (TEM): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Neither Biogen (BIIB) nor Tempus AI (TEM) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

BIIB

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

BIIB
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

TEM
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Biogen (BIIB) vs. Tempus AI (TEM): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Biogen (BIIB) and Tempus AI (TEM)
MetricBIIBTEM
Dividend Yield (TTM)0.00%0.00%
Dividend Payout Ratio (TTM)0.00%0.00%

Valuation

P/E Ratio (TTM)

An earnings multiple is available for just one side: Biogen (BIIB) trades at 107.51 times trailing earnings, ranked against its peers, while Tempus AI (TEM) has no P/E ratio this period.

BIIB

Pharmaceuticals, Biotechnology & Life Sciences industry group

107.51

BIIB
107.51
Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
TEM
--
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Biogen (BIIB) vs. Tempus AI (TEM): TEM does not report P/E ratio, so it has no value marker; BIIB is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

P/S Ratio (TTM)

On P/S ratio, both Biogen (BIIB) at 3.57 and Tempus AI (TEM) at 9.19 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

BIIB

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.57

Max
58.18
Q3
25.77
Median
7.30
BIIB
3.57
Q1
3.01
Min
0.01

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

9.19

Max
58.18
Q3
25.77
TEM
9.19
Median
7.30
Q1
3.01
Min
0.01
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Biogen (BIIB) vs. Tempus AI (TEM): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Biogen (BIIB) at 1.94 sits near its industry’s typical P/B ratio, while Tempus AI (TEM) at 27.66 prices above its benchmark range — TEM looks rich relative to book.

BIIB

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.94

Max
13.53
Q3
6.54
Median
3.25
BIIB
1.94
Q1
1.69
Min
-5.59

TEM

Pharmaceuticals, Biotechnology & Life Sciences industry group

27.66

TEM
27.66
Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
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Biogen (BIIB) vs. Tempus AI (TEM): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Biogen (BIIB) and Tempus AI (TEM)
MetricBIIBTEM
P/E Ratio (TTM)107.51--
P/S Ratio (TTM)3.579.19
P/B Ratio (MRQ)1.9427.66
Free Cash Flow Yield (TTM)2.20%0.30%