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BIIB vs. NTRA: Biogen vs. Natera Stock Comparison

How do Biogen (BIIB) and Natera (NTRA) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Biogen (BIIB) and Natera (NTRA) are both classified in the Biotechnology sub-industry within the broader Biotechnology industry, placing them in the closest GICS peer bucket.

Company profile comparison for Biogen (BIIB) and Natera (NTRA)
Profile ItemBIIBNTRA
NameBiogen Inc.Natera, Inc.
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyBiotechnology
GICS Sub-IndustryBiotechnologyBiotechnology
Market Capitalization36.71 billion USD45.05 billion USD
CurrencyUSDUSD
ExchangeNasdaqNasdaq
Listing DateSeptember 17, 1991July 1, 2015
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

BIIB
NTRA
GSPC
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Biogen (BIIB) vs. Natera (NTRA), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Biogen (BIIB) and Natera (NTRA). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Biogen (BIIB) and Natera (NTRA). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Biogen (BIIB) and Natera (NTRA)
MetricBIIBNTRA
Total Return (1Y)65.44%61.03%
Total Return (3Y, Annualized)4.62%92.02%
Total Return (5Y, Annualized)-0.96%23.20%

Risk Profile

Drawdown History

BIIB
NTRA
GSPC
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Biogen (BIIB) vs. Natera (NTRA), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Biogen (BIIB) and Natera (NTRA). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Natera (NTRA) has an aggressive beta of 1.58, indicating higher sensitivity to broad-market moves, while Biogen (BIIB) is defensive at 0.08 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.

Risk profile metrics for Biogen (BIIB) and Natera (NTRA)
MetricBIIBNTRA
Volatility (1Y, Annualized)34.58%52.30%
Beta (5Y)0.081.58
Max Drawdown (5Y)-64.35%-75.72%
Avg. Volume (3M)1.05M1.68M

Risk-Adjusted Performance

Risk-Return Positioning

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BIIB and NTRA are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Biogen (BIIB) and Natera (NTRA)
MetricBIIBNTRA
Sharpe Ratio (1Y)1.771.09
Sortino Ratio (1Y)2.771.63

Profitability

ROE (TTM)

Natera (NTRA) reports a negative ROE of -10.55%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile Biogen (BIIB) reports 1.87%, ranking against industry peers normally.

BIIB

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.87%

Max
109.18%
Q3
6.23%
BIIB
1.87%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

-10.55%

Max
109.18%
Q3
6.23%
NTRA
-10.55%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Biogen (BIIB) vs. Natera (NTRA): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Natera (NTRA) reports a negative net margin of -5.66%, usually indicating a net loss over the period. Meanwhile Biogen (BIIB) reports 3.38%, ranking against industry peers normally.

BIIB

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.38%

Max
18.05%
Q3
4.78%
BIIB
3.38%
Median
0.00%
Q1
-4.14%
Min
-17.05%

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

-5.66%

Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
NTRA
-5.66%
Min
-17.05%
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Biogen (BIIB) vs. Natera (NTRA): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Natera (NTRA) reports a negative operating margin of -7.64%, usually indicating that operating costs exceeded revenue at the operating-income line. Meanwhile Biogen (BIIB) reports 24.12%, ranking against industry peers normally.

BIIB

Pharmaceuticals, Biotechnology & Life Sciences industry group

24.12%

Max
83.12%
BIIB
24.12%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

-7.64%

Max
83.12%
Q3
14.77%
Median
0.00%
NTRA
-7.64%
Q1
-78.82%
Min
-207.40%
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Biogen (BIIB) vs. Natera (NTRA): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Biogen (BIIB) and Natera (NTRA)
MetricBIIBNTRA
ROE (TTM)1.87%-10.55%
ROA (TTM)4.94%-6.79%
Net Margin (TTM)3.38%-5.66%
Operating Margin (TTM)24.12%-7.64%
Gross Margin (TTM)75.77%65.14%

Growth

Revenue Growth

Both Biogen (BIIB) at 2.22% and Natera (NTRA) at 35.90% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

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Biogen (BIIB) vs. Natera (NTRA): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: Biogen (BIIB) reports EPS growth of -21.38%, ranked against its industry; Natera (NTRA) has no EPS growth figure this period.

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Biogen (BIIB) vs. Natera (NTRA): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Biogen (BIIB) and Natera (NTRA)
MetricBIIBNTRA
Revenue Growth (YoY)2.22%35.90%
Revenue Growth (3Y CAGR)-0.94%41.14%
EPS Growth (YoY)-21.38%--
EPS Growth (3Y CAGR)-25.04%--

Financial Strength

Current Ratio (MRQ)

Natera (NTRA) at 2.81 keeps current ratio within its industry’s typical mid-range, while Biogen (BIIB) at 1.95 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for BIIB.

BIIB

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.95

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
BIIB
1.95
Min
0.10

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.81

Max
25.13
Q3
12.13
Median
5.52
NTRA
2.81
Q1
2.47
Min
0.10
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Biogen (BIIB) vs. Natera (NTRA): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Both Biogen (BIIB) at 0.41 and Natera (NTRA) at 0.13 fund their balance sheets with roughly industry-typical debt-to-equity mixes.

BIIB

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.41

Max
1.42
Q3
0.65
BIIB
0.41
Median
0.15
Q1
0.02
Min
0.00

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.13

Max
1.42
Q3
0.65
Median
0.15
NTRA
0.13
Q1
0.02
Min
0.00
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Biogen (BIIB) vs. Natera (NTRA): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Biogen (BIIB) and Natera (NTRA)
MetricBIIBNTRA
Current Ratio (MRQ)1.952.81
Debt / Equity (MRQ)0.410.13
Net Debt / EBITDA1.97--

Dividends

Dividend Yield (TTM)

Neither Biogen (BIIB) nor Natera (NTRA) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

BIIB

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

BIIB
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

NTRA
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Biogen (BIIB) vs. Natera (NTRA): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Neither Biogen (BIIB) nor Natera (NTRA) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

BIIB

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

BIIB
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

NTRA
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Biogen (BIIB) vs. Natera (NTRA): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Biogen (BIIB) and Natera (NTRA)
MetricBIIBNTRA
Dividend Yield (TTM)0.00%0.00%
Dividend Payout Ratio (TTM)0.00%0.00%

Valuation

P/E Ratio (TTM)

An earnings multiple is available for just one side: Biogen (BIIB) trades at 107.51 times trailing earnings, ranked against its peers, while Natera (NTRA) has no P/E ratio this period.

BIIB

Pharmaceuticals, Biotechnology & Life Sciences industry group

107.51

BIIB
107.51
Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
NTRA
--
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Biogen (BIIB) vs. Natera (NTRA): NTRA does not report P/E ratio, so it has no value marker; BIIB is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

P/S Ratio (TTM)

On P/S ratio, both Biogen (BIIB) at 3.57 and Natera (NTRA) at 15.49 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

BIIB

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.57

Max
58.18
Q3
25.77
Median
7.30
BIIB
3.57
Q1
3.01
Min
0.01

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

15.49

Max
58.18
Q3
25.77
NTRA
15.49
Median
7.30
Q1
3.01
Min
0.01
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Biogen (BIIB) vs. Natera (NTRA): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Biogen (BIIB) at 1.94 sits near its industry’s typical P/B ratio, while Natera (NTRA) at 23.99 prices above its benchmark range — NTRA looks rich relative to book.

BIIB

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.94

Max
13.53
Q3
6.54
Median
3.25
BIIB
1.94
Q1
1.69
Min
-5.59

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

23.99

NTRA
23.99
Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
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Biogen (BIIB) vs. Natera (NTRA): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Biogen (BIIB) and Natera (NTRA)
MetricBIIBNTRA
P/E Ratio (TTM)107.51--
P/S Ratio (TTM)3.5715.49
P/B Ratio (MRQ)1.9423.99
Free Cash Flow Yield (TTM)2.20%0.19%