ALGN vs. PEN: Align vs. Penumbra Stock Comparison

November 11, 2026

How do Align (ALGN) and Penumbra (PEN) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Align (ALGN) and Penumbra (PEN) both belong to the Health Care Equipment & Supplies industry, though ALGN is classified under Health Care Supplies while PEN falls under Health Care Equipment.

Company profile comparison for Align (ALGN) and Penumbra (PEN)
Profile Item	ALGN	PEN
Name	Align Technology Inc.	Penumbra Inc.
Country/Region	United States	United States
GICS Sector	Health Care	Health Care
GICS Industry Group	Health Care Equipment & Services	Health Care Equipment & Services
GICS Industry	Health Care Equipment & Supplies	Health Care Equipment & Supplies
GICS Sub-Industry	Health Care Supplies	Health Care Equipment
Market Capitalization	11.70 billion USD	12.58 billion USD
Currency	USD	USD
Exchange	Nasdaq	NYSE
Listing Date	January 30, 2001	September 18, 2015
Security Type	Common Stock	Common Stock

Price Performance

Cumulative Growth

ALGN

PEN

GSPC

Align (ALGN) vs. Penumbra (PEN), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Align (ALGN) and Penumbra (PEN). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Align (ALGN) and Penumbra (PEN). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Align (ALGN) and Penumbra (PEN)
Metric	ALGN	PEN
Total Return (1Y)	27.43%	20.52%
Total Return (3Y, Annualized)	-2.84%	20.38%
Total Return (5Y, Annualized)	-24.73%	3.15%

Risk Profile

Drawdown History

ALGN

PEN

GSPC

Align (ALGN) vs. Penumbra (PEN), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Align (ALGN) and Penumbra (PEN). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Align (ALGN) has an aggressive beta of 1.67, indicating higher sensitivity to broad-market moves, while Penumbra (PEN) is defensive at 0.68 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.

Risk profile metrics for Align (ALGN) and Penumbra (PEN)
Metric	ALGN	PEN
Volatility (1Y, Annualized)	40.49%	19.78%
Beta (5Y)	1.67	0.68
Max Drawdown (5Y)	-82.44%	-59.60%
Avg. Volume (3M)	942.14K	348.64K

Risk-Adjusted Performance

Risk-Return Positioning

ALGN and PEN are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Align (ALGN) and Penumbra (PEN)
Metric	ALGN	PEN
Sharpe Ratio (1Y)	0.57	0.82
Sortino Ratio (1Y)	0.89	1.56

Profitability

ROE (TTM)

Both Align (ALGN) at 11.91% and Penumbra (PEN) at 10.67% land near their industries’ usual ROE ranges, so capital efficiency looks broadly in line with peers on both sides.

ALGN

Health Care Equipment & Services industry group

11.91%

Max: 47.61%
Q3: 14.36%
ALGN: 11.91%
Median: 5.45%
Q1: -10.67%
Min: -47.01%

PEN

Health Care Equipment & Services industry group

10.67%

Max: 47.61%
Q3: 14.36%
PEN: 10.67%
Median: 5.45%
Q1: -10.67%
Min: -47.01%

Align (ALGN) vs. Penumbra (PEN): A comparison of their ROE against the Health Care Equipment & Services industry group benchmark.

Net Margin (TTM)

For every dollar of sales, both Align (ALGN) at 11.83% and Penumbra (PEN) at 10.06% retain more as net profit than most peers, landing in the top net margin quartile of their industries.

ALGN

Health Care Equipment & Services industry group

11.83%

Max: 29.35%
ALGN: 11.83%
Q3: 9.33%
Median: 2.18%
Q1: -6.29%
Min: -28.46%

PEN

Health Care Equipment & Services industry group

10.06%

Max: 29.35%
PEN: 10.06%
Q3: 9.33%
Median: 2.18%
Q1: -6.29%
Min: -28.46%

Align (ALGN) vs. Penumbra (PEN): A comparison of their net margin against the Health Care Equipment & Services industry group benchmark.

Operating Margin (TTM)

Align (ALGN) at 20.13% operates in the top operating margin quartile, ahead of Penumbra (PEN) at 12.37%, which runs around its industry’s norm.

ALGN

Health Care Equipment & Services industry group

20.13%

Max: 35.43%
ALGN: 20.13%
Q3: 14.14%
Median: 6.81%
Q1: -0.28%
Min: -16.29%

PEN

Health Care Equipment & Services industry group

12.37%

Max: 35.43%
Q3: 14.14%
PEN: 12.37%
Median: 6.81%
Q1: -0.28%
Min: -16.29%

Align (ALGN) vs. Penumbra (PEN): A comparison of their operating margin against the Health Care Equipment & Services industry group benchmark.

Profitability Metrics

Profitability metrics for Align (ALGN) and Penumbra (PEN)
Metric	ALGN	PEN
ROE (TTM)	11.91%	10.67%
ROA (TTM)	8.01%	6.28%
Net Margin (TTM)	11.83%	10.06%
Operating Margin (TTM)	20.13%	12.37%
Gross Margin (TTM)	71.53%	67.99%

Growth

Revenue Growth

Penumbra (PEN) at 17.50% is around its peer norm for revenue growth, while Align (ALGN) at 0.90% drops into the bottom quartile, signaling weaker demand or pricing momentum.

Align (ALGN) vs. Penumbra (PEN): A comparison of their Revenue Growth across different time periods.

EPS Growth

Penumbra (PEN) at 1,155.56% clears its industry range for EPS growth, a much stronger earnings trajectory than Align (ALGN) at 0.53%, which is closer to a typical peer reading.

Align (ALGN) vs. Penumbra (PEN): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Align (ALGN) and Penumbra (PEN)
Metric	ALGN	PEN
Revenue Growth (YoY)	0.90%	17.50%
Revenue Growth (3Y CAGR)	2.61%	18.33%
EPS Growth (YoY)	0.53%	1,155.56%
EPS Growth (3Y CAGR)	7.02%	--

Financial Strength

Current Ratio (MRQ)

Align (ALGN) at 1.43 keeps current ratio within its industry’s typical mid-range, while Penumbra (PEN) at 5.89 sits above its industry’s typical mid-range — comfortable liquidity, though possibly with more idle current assets relative to peers.

ALGN

Health Care Equipment & Services industry group

1.43

Max: 7.59
Q3: 4.00
Median: 1.98
ALGN: 1.43
Q1: 1.37
Min: 0.30

PEN

Health Care Equipment & Services industry group

5.89

Max: 7.59
PEN: 5.89
Q3: 4.00
Median: 1.98
Q1: 1.37
Min: 0.30

Align (ALGN) vs. Penumbra (PEN): A comparison of their current ratio against the Health Care Equipment & Services industry group benchmark.

Debt / Equity (MRQ)

Both Align (ALGN) at 0.03 and Penumbra (PEN) at 0.13 keep leverage in the lower quartile of their industries, with less balance-sheet debt relative to equity than most peers.

ALGN

Health Care Equipment & Services industry group

0.03

Max: 1.88
Q3: 0.91
Median: 0.58
Q1: 0.16
ALGN: 0.03
Min: 0.00

PEN

Health Care Equipment & Services industry group

0.13

Max: 1.88
Q3: 0.91
Median: 0.58
Q1: 0.16
PEN: 0.13
Min: 0.00

Align (ALGN) vs. Penumbra (PEN): A comparison of their debt-to-equity ratio against the Health Care Equipment & Services industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Align (ALGN) and Penumbra (PEN)
Metric	ALGN	PEN
Current Ratio (MRQ)	1.43	5.89
Debt / Equity (MRQ)	0.03	0.13
Net Debt / EBITDA	-1.04	-2.22

Dividends

Dividend Yield (TTM)

Neither Align (ALGN) nor Penumbra (PEN) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

ALGN

Health Care Equipment & Services industry group

0.00%

ALGN: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

PEN

Health Care Equipment & Services industry group

0.00%

PEN: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Align (ALGN) vs. Penumbra (PEN): A comparison of their dividend yield against the Health Care Equipment & Services industry group benchmark.

Dividend Payout Ratio (TTM)

Neither Align (ALGN) nor Penumbra (PEN) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

ALGN

Health Care Equipment & Services industry group

0.00%

ALGN: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

PEN

Health Care Equipment & Services industry group

0.00%

PEN: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Align (ALGN) vs. Penumbra (PEN): A comparison of their payout ratio against the Health Care Equipment & Services industry group benchmark.

Dividend Metrics

Dividend metrics for Align (ALGN) and Penumbra (PEN)
Metric	ALGN	PEN
Dividend Yield (TTM)	0.00%	0.00%
Dividend Payout Ratio (TTM)	0.00%	0.00%

Valuation

P/E Ratio (TTM)

Align (ALGN) at 24.20 is near its industry’s usual P/E ratio, while Penumbra (PEN) at 80.41 sits in the richer quartile — PEN needs stronger growth or earnings quality to justify the premium.

ALGN

Health Care Equipment & Services industry group

24.20

Max: 80.41
Q3: 47.62
Median: 29.93
ALGN: 24.20
Q1: 21.19
Min: 4.21

PEN

Health Care Equipment & Services industry group

80.41

PEN: 80.41
Max: 80.41
Q3: 47.62
Median: 29.93
Q1: 21.19
Min: 4.21

Align (ALGN) vs. Penumbra (PEN): A comparison of their P/E ratio against the Health Care Equipment & Services industry group benchmark.

P/S Ratio (TTM)

Align (ALGN) at 2.81 is priced about in line with its industry on P/S ratio, while Penumbra (PEN) at 8.06 sits in the pricier quartile — PEN costs more per dollar of sales.

ALGN

Health Care Equipment & Services industry group

2.81

Max: 8.80
Q3: 4.32
ALGN: 2.81
Median: 2.13
Q1: 1.10
Min: 0.03

PEN

Health Care Equipment & Services industry group

8.06

Max: 8.80
PEN: 8.06
Q3: 4.32
Median: 2.13
Q1: 1.10
Min: 0.03

Align (ALGN) vs. Penumbra (PEN): A comparison of their P/S ratio against the Health Care Equipment & Services industry group benchmark.

P/B Ratio (MRQ)

Align (ALGN) at 2.73 is valued about in line with its industry on P/B ratio, while Penumbra (PEN) at 7.95 carries an above-peer premium to book — PEN is pricier on assets.

ALGN

Health Care Equipment & Services industry group

2.73

Max: 11.68
Q3: 6.12
Median: 3.00
ALGN: 2.73
Q1: 1.73
Min: -1.31

PEN

Health Care Equipment & Services industry group

7.95

Max: 11.68
PEN: 7.95
Q3: 6.12
Median: 3.00
Q1: 1.73
Min: -1.31

Align (ALGN) vs. Penumbra (PEN): A comparison of their P/B ratio against the Health Care Equipment & Services industry group benchmark.

Valuation Metrics

Valuation metrics for Align (ALGN) and Penumbra (PEN)
Metric	ALGN	PEN
P/E Ratio (TTM)	24.20	80.41
P/S Ratio (TTM)	2.81	8.06
P/B Ratio (MRQ)	2.73	7.95
Free Cash Flow Yield (TTM)	4.90%	1.32%