ALGN vs. ISRG: Align vs. Intuitive Surgical Stock Comparison

November 11, 2026

How do Align (ALGN) and Intuitive Surgical (ISRG) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Align (ALGN) and Intuitive Surgical (ISRG) both belong to the Health Care Equipment & Supplies industry, though ALGN is classified under Health Care Supplies while ISRG falls under Health Care Equipment.

Company profile comparison for Align (ALGN) and Intuitive Surgical (ISRG)
Profile Item	ALGN	ISRG
Name	Align Technology Inc.	Intuitive Surgical Inc.
Country/Region	United States	United States
GICS Sector	Health Care	Health Care
GICS Industry Group	Health Care Equipment & Services	Health Care Equipment & Services
GICS Industry	Health Care Equipment & Supplies	Health Care Equipment & Supplies
GICS Sub-Industry	Health Care Supplies	Health Care Equipment
Market Capitalization	11.70 billion USD	159.96 billion USD
Currency	USD	USD
Exchange	Nasdaq	Nasdaq
Listing Date	January 30, 2001	June 16, 2000
Security Type	Common Stock	Common Stock

Price Performance

Cumulative Growth

ALGN

ISRG

GSPC

Align (ALGN) vs. Intuitive Surgical (ISRG), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

Loading price history…

Trailing total returns for Align (ALGN) and Intuitive Surgical (ISRG). Returns over one year are annualized.

Calendar-Year Returns

Loading price history…

Calendar-year total returns for Align (ALGN) and Intuitive Surgical (ISRG). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Align (ALGN) and Intuitive Surgical (ISRG)
Metric	ALGN	ISRG
Total Return (1Y)	27.43%	-17.61%
Total Return (3Y, Annualized)	-2.84%	19.20%
Total Return (5Y, Annualized)	-24.73%	4.85%

Risk Profile

Drawdown History

ALGN

ISRG

GSPC

Align (ALGN) vs. Intuitive Surgical (ISRG), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

Loading price history…

Distribution of monthly total returns for Align (ALGN) and Intuitive Surgical (ISRG). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Align (ALGN) and Intuitive Surgical (ISRG)
Metric	ALGN	ISRG
Volatility (1Y, Annualized)	40.49%	35.53%
Beta (5Y)	1.67	1.41
Max Drawdown (5Y)	-82.44%	-49.88%
Avg. Volume (3M)	942.14K	2.43M

Risk-Adjusted Performance

Risk-Return Positioning

ALGN and ISRG are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Align (ALGN) and Intuitive Surgical (ISRG)
Metric	ALGN	ISRG
Sharpe Ratio (1Y)	0.57	-0.62
Sortino Ratio (1Y)	0.89	-0.83

Profitability

ROE (TTM)

Intuitive Surgical (ISRG) at 17.93% sits in the top ROE quartile, while Align (ALGN) at 11.91% is closer to the peer norm — stronger capital efficiency for ISRG.

ALGN

Health Care Equipment & Services industry group

11.91%

Max: 47.61%
Q3: 14.36%
ALGN: 11.91%
Median: 5.45%
Q1: -10.67%
Min: -47.01%

ISRG

Health Care Equipment & Services industry group

17.93%

Max: 47.61%
ISRG: 17.93%
Q3: 14.36%
Median: 5.45%
Q1: -10.67%
Min: -47.01%

Align (ALGN) vs. Intuitive Surgical (ISRG): A comparison of their ROE against the Health Care Equipment & Services industry group benchmark.

Net Margin (TTM)

For every dollar of sales, both Align (ALGN) at 11.83% and Intuitive Surgical (ISRG) at 25.54% retain more as net profit than most peers, landing in the top net margin quartile of their industries.

ALGN

Health Care Equipment & Services industry group

11.83%

Max: 29.35%
ALGN: 11.83%
Q3: 9.33%
Median: 2.18%
Q1: -6.29%
Min: -28.46%

ISRG

Health Care Equipment & Services industry group

25.54%

Max: 29.35%
ISRG: 25.54%
Q3: 9.33%
Median: 2.18%
Q1: -6.29%
Min: -28.46%

Align (ALGN) vs. Intuitive Surgical (ISRG): A comparison of their net margin against the Health Care Equipment & Services industry group benchmark.

Operating Margin (TTM)

Both Align (ALGN) at 20.13% and Intuitive Surgical (ISRG) at 33.29% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

ALGN

Health Care Equipment & Services industry group

20.13%

Max: 35.43%
ALGN: 20.13%
Q3: 14.14%
Median: 6.81%
Q1: -0.28%
Min: -16.29%

ISRG

Health Care Equipment & Services industry group

33.29%

Max: 35.43%
ISRG: 33.29%
Q3: 14.14%
Median: 6.81%
Q1: -0.28%
Min: -16.29%

Align (ALGN) vs. Intuitive Surgical (ISRG): A comparison of their operating margin against the Health Care Equipment & Services industry group benchmark.

Profitability Metrics

Profitability metrics for Align (ALGN) and Intuitive Surgical (ISRG)
Metric	ALGN	ISRG
ROE (TTM)	11.91%	17.93%
ROA (TTM)	8.01%	11.86%
Net Margin (TTM)	11.83%	25.54%
Operating Margin (TTM)	20.13%	33.29%
Gross Margin (TTM)	71.53%	66.64%

Growth

Revenue Growth

Intuitive Surgical (ISRG) at 20.51% sits in the top revenue growth quartile, while Align (ALGN) at 0.90% is in the bottom quartile, showing a clear gap in revenue momentum.

Align (ALGN) vs. Intuitive Surgical (ISRG): A comparison of their Revenue Growth across different time periods.

EPS Growth

Both Align (ALGN) at 0.53% and Intuitive Surgical (ISRG) at 22.59% land near their industries' usual EPS growth ranges, so bottom-line momentum looks broadly in line with peers on both sides.

Align (ALGN) vs. Intuitive Surgical (ISRG): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Align (ALGN) and Intuitive Surgical (ISRG)
Metric	ALGN	ISRG
Revenue Growth (YoY)	0.90%	20.51%
Revenue Growth (3Y CAGR)	2.61%	17.39%
EPS Growth (YoY)	0.53%	22.59%
EPS Growth (3Y CAGR)	7.02%	29.19%

Financial Strength

Current Ratio (MRQ)

Both Align (ALGN) at 1.43 and Intuitive Surgical (ISRG) at 3.33 carry current ratio within their industries’ typical mid-ranges, suggesting balanced short-term liquidity relative to peers.

ALGN

Health Care Equipment & Services industry group

1.43

Max: 7.59
Q3: 4.00
Median: 1.98
ALGN: 1.43
Q1: 1.37
Min: 0.30

ISRG

Health Care Equipment & Services industry group

3.33

Max: 7.59
Q3: 4.00
ISRG: 3.33
Median: 1.98
Q1: 1.37
Min: 0.30

Align (ALGN) vs. Intuitive Surgical (ISRG): A comparison of their current ratio against the Health Care Equipment & Services industry group benchmark.

Debt / Equity (MRQ)

Only one side’s leverage can be read here: Align (ALGN) carries debt-to-equity ratio of 0.03 against its industry range, while Intuitive Surgical (ISRG) reports no figure this period.

ALGN

Health Care Equipment & Services industry group

0.03

Max: 1.88
Q3: 0.91
Median: 0.58
Q1: 0.16
ALGN: 0.03
Min: 0.00

ISRG

Health Care Equipment & Services industry group

Max: 1.88
Q3: 0.91
Median: 0.58
Q1: 0.16
Min: 0.00
ISRG: --

Align (ALGN) vs. Intuitive Surgical (ISRG): ISRG does not report debt-to-equity ratio, so it has no value marker; ALGN is benchmarked against the Health Care Equipment & Services industry group.

Financial Strength Metrics

Financial strength metrics for Align (ALGN) and Intuitive Surgical (ISRG)
Metric	ALGN	ISRG
Current Ratio (MRQ)	1.43	3.33
Debt / Equity (MRQ)	0.03	--
Net Debt / EBITDA	-1.04	-0.90

Dividends

Dividend Yield (TTM)

Neither Align (ALGN) nor Intuitive Surgical (ISRG) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

ALGN

Health Care Equipment & Services industry group

0.00%

ALGN: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

ISRG

Health Care Equipment & Services industry group

0.00%

ISRG: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Align (ALGN) vs. Intuitive Surgical (ISRG): A comparison of their dividend yield against the Health Care Equipment & Services industry group benchmark.

Dividend Payout Ratio (TTM)

Neither Align (ALGN) nor Intuitive Surgical (ISRG) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

ALGN

Health Care Equipment & Services industry group

0.00%

ALGN: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

ISRG

Health Care Equipment & Services industry group

0.00%

ISRG: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Align (ALGN) vs. Intuitive Surgical (ISRG): A comparison of their payout ratio against the Health Care Equipment & Services industry group benchmark.

Dividend Metrics

Dividend metrics for Align (ALGN) and Intuitive Surgical (ISRG)
Metric	ALGN	ISRG
Dividend Yield (TTM)	0.00%	0.00%
Dividend Payout Ratio (TTM)	0.00%	0.00%

Valuation

P/E Ratio (TTM)

Align (ALGN) at 24.20 is near its industry’s usual P/E ratio, while Intuitive Surgical (ISRG) at 54.75 sits in the richer quartile — ISRG needs stronger growth or earnings quality to justify the premium.

ALGN

Health Care Equipment & Services industry group

24.20

Max: 80.41
Q3: 47.62
Median: 29.93
ALGN: 24.20
Q1: 21.19
Min: 4.21

ISRG

Health Care Equipment & Services industry group

54.75

Max: 80.41
ISRG: 54.75
Q3: 47.62
Median: 29.93
Q1: 21.19
Min: 4.21

Align (ALGN) vs. Intuitive Surgical (ISRG): A comparison of their P/E ratio against the Health Care Equipment & Services industry group benchmark.

P/S Ratio (TTM)

Align (ALGN) at 2.81 prices around its industry’s typical P/S ratio, while Intuitive Surgical (ISRG) at 13.82 clears its benchmark range — ISRG looks notably rich on sales.

ALGN

Health Care Equipment & Services industry group

2.81

Max: 8.80
Q3: 4.32
ALGN: 2.81
Median: 2.13
Q1: 1.10
Min: 0.03

ISRG

Health Care Equipment & Services industry group

13.82

ISRG: 13.82
Max: 8.80
Q3: 4.32
Median: 2.13
Q1: 1.10
Min: 0.03

Align (ALGN) vs. Intuitive Surgical (ISRG): A comparison of their P/S ratio against the Health Care Equipment & Services industry group benchmark.

P/B Ratio (MRQ)

Align (ALGN) at 2.73 is valued about in line with its industry on P/B ratio, while Intuitive Surgical (ISRG) at 9.82 carries an above-peer premium to book — ISRG is pricier on assets.

ALGN

Health Care Equipment & Services industry group

2.73

Max: 11.68
Q3: 6.12
Median: 3.00
ALGN: 2.73
Q1: 1.73
Min: -1.31

ISRG

Health Care Equipment & Services industry group

9.82

Max: 11.68
ISRG: 9.82
Q3: 6.12
Median: 3.00
Q1: 1.73
Min: -1.31

Align (ALGN) vs. Intuitive Surgical (ISRG): A comparison of their P/B ratio against the Health Care Equipment & Services industry group benchmark.

Valuation Metrics

Valuation metrics for Align (ALGN) and Intuitive Surgical (ISRG)
Metric	ALGN	ISRG
P/E Ratio (TTM)	24.20	54.75
P/S Ratio (TTM)	2.81	13.82
P/B Ratio (MRQ)	2.73	9.82
Free Cash Flow Yield (TTM)	4.90%	2.15%