NTRA vs. TECH: Natera vs. Bio-Techne Stock Comparison

November 11, 2026

How do Natera (NTRA) and Bio-Techne (TECH) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Natera (NTRA) and Bio-Techne (TECH) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but NTRA is classified in Biotechnology while TECH is classified in Life Sciences Tools & Services.

Company profile comparison for Natera (NTRA) and Bio-Techne (TECH)
Profile Item	NTRA	TECH
Name	Natera, Inc.	Bio-Techne Corp.
Country/Region	United States	United States
GICS Sector	Health Care	Health Care
GICS Industry Group	Pharmaceuticals, Biotechnology & Life Sciences	Pharmaceuticals, Biotechnology & Life Sciences
GICS Industry	Biotechnology	Life Sciences Tools & Services
GICS Sub-Industry	Biotechnology	Life Sciences Tools & Services
Market Capitalization	45.05 billion USD	11.43 billion USD
Currency	USD	USD
Exchange	Nasdaq	Nasdaq
Listing Date	July 1, 2015	February 9, 1989
Security Type	Common Stock	Common Stock

Price Performance

Cumulative Growth

NTRA

TECH

GSPC

Natera (NTRA) vs. Bio-Techne (TECH), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Natera (NTRA) and Bio-Techne (TECH). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Natera (NTRA) and Bio-Techne (TECH). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Natera (NTRA) and Bio-Techne (TECH)
Metric	NTRA	TECH
Total Return (1Y)	61.03%	27.56%
Total Return (3Y, Annualized)	92.02%	9.11%
Total Return (5Y, Annualized)	23.20%	-9.91%

Risk Profile

Drawdown History

NTRA

TECH

GSPC

Natera (NTRA) vs. Bio-Techne (TECH), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Natera (NTRA) and Bio-Techne (TECH). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Natera (NTRA) and Bio-Techne (TECH)
Metric	NTRA	TECH
Volatility (1Y, Annualized)	52.30%	43.08%
Beta (5Y)	1.58	1.26
Max Drawdown (5Y)	-75.72%	-65.87%
Avg. Volume (3M)	1.68M	2.81M

Risk-Adjusted Performance

Risk-Return Positioning

NTRA and TECH are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Natera (NTRA) and Bio-Techne (TECH)
Metric	NTRA	TECH
Sharpe Ratio (1Y)	1.09	0.54
Sortino Ratio (1Y)	1.63	0.82

Profitability

ROE (TTM)

Natera (NTRA) reports a negative ROE of -10.55%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile Bio-Techne (TECH) reports 8.33%, ranking against industry peers normally.

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

-10.55%

Max: 109.18%
Q3: 6.23%
NTRA: -10.55%
Median: -26.66%
Q1: -64.05%
Min: -167.77%

TECH

Pharmaceuticals, Biotechnology & Life Sciences industry group

8.33%

Max: 109.18%
TECH: 8.33%
Q3: 6.23%
Median: -26.66%
Q1: -64.05%
Min: -167.77%

Natera (NTRA) vs. Bio-Techne (TECH): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Natera (NTRA) reports a negative net margin of -5.66%, usually indicating a net loss over the period. Meanwhile Bio-Techne (TECH) reports 14.00%, ranking against industry peers normally.

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

-5.66%

Max: 18.05%
Q3: 4.78%
Median: 0.00%
Q1: -4.14%
NTRA: -5.66%
Min: -17.05%

TECH

Pharmaceuticals, Biotechnology & Life Sciences industry group

14.00%

Max: 18.05%
TECH: 14.00%
Q3: 4.78%
Median: 0.00%
Q1: -4.14%
Min: -17.05%

Natera (NTRA) vs. Bio-Techne (TECH): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Natera (NTRA) reports a negative operating margin of -7.64%, usually indicating that operating costs exceeded revenue at the operating-income line. Meanwhile Bio-Techne (TECH) reports 12.21%, ranking against industry peers normally.

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

-7.64%

Max: 83.12%
Q3: 14.77%
Median: 0.00%
NTRA: -7.64%
Q1: -78.82%
Min: -207.40%

TECH

Pharmaceuticals, Biotechnology & Life Sciences industry group

12.21%

Max: 83.12%
Q3: 14.77%
TECH: 12.21%
Median: 0.00%
Q1: -78.82%
Min: -207.40%

Natera (NTRA) vs. Bio-Techne (TECH): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Natera (NTRA) and Bio-Techne (TECH)
Metric	NTRA	TECH
ROE (TTM)	-10.55%	8.33%
ROA (TTM)	-6.79%	6.38%
Net Margin (TTM)	-5.66%	14.00%
Operating Margin (TTM)	-7.64%	12.21%
Gross Margin (TTM)	65.14%	66.23%

Growth

Revenue Growth

Both Natera (NTRA) at 35.90% and Bio-Techne (TECH) at -0.38% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

Natera (NTRA) vs. Bio-Techne (TECH): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: Bio-Techne (TECH) reports EPS growth of 152.17%, ranked against its industry; Natera (NTRA) has no EPS growth figure this period.

Natera (NTRA) vs. Bio-Techne (TECH): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Natera (NTRA) and Bio-Techne (TECH)
Metric	NTRA	TECH
Revenue Growth (YoY)	35.90%	-0.38%
Revenue Growth (3Y CAGR)	41.14%	2.25%
EPS Growth (YoY)	--	152.17%
EPS Growth (3Y CAGR)	--	-12.97%

Financial Strength

Current Ratio (MRQ)

Natera (NTRA) at 2.81 keeps current ratio within its industry’s typical mid-range, while Bio-Techne (TECH) at 2.28 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for TECH.

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.81

Max: 25.13
Q3: 12.13
Median: 5.52
NTRA: 2.81
Q1: 2.47
Min: 0.10

TECH

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.28

Max: 25.13
Q3: 12.13
Median: 5.52
Q1: 2.47
TECH: 2.28
Min: 0.10

Natera (NTRA) vs. Bio-Techne (TECH): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Both Natera (NTRA) at 0.13 and Bio-Techne (TECH) at 0.13 fund their balance sheets with roughly industry-typical debt-to-equity mixes.

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.13

Max: 1.42
Q3: 0.65
Median: 0.15
NTRA: 0.13
Q1: 0.02
Min: 0.00

TECH

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.13

Max: 1.42
Q3: 0.65
Median: 0.15
TECH: 0.13
Q1: 0.02
Min: 0.00

Natera (NTRA) vs. Bio-Techne (TECH): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Natera (NTRA) and Bio-Techne (TECH)
Metric	NTRA	TECH
Current Ratio (MRQ)	2.81	2.28
Debt / Equity (MRQ)	0.13	0.13
Net Debt / EBITDA	--	-0.20

Dividends

Dividend Yield (TTM)

Natera (NTRA) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Bio-Techne (TECH) reports a yield of 0.44%, ranking against industry peers normally.

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

NTRA: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

TECH

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.44%

TECH: 0.44%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Natera (NTRA) vs. Bio-Techne (TECH): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Natera (NTRA) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Bio-Techne (TECH) reports a payout of 27.59%, ranking against industry peers normally.

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

NTRA: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

TECH

Pharmaceuticals, Biotechnology & Life Sciences industry group

27.59%

TECH: 27.59%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Natera (NTRA) vs. Bio-Techne (TECH): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Natera (NTRA) and Bio-Techne (TECH)
Metric	NTRA	TECH
Dividend Yield (TTM)	0.00%	0.44%
Dividend Payout Ratio (TTM)	0.00%	27.59%

Valuation

P/E Ratio (TTM)

An earnings multiple is available for just one side: Bio-Techne (TECH) trades at 62.74 times trailing earnings, ranked against its peers, while Natera (NTRA) has no P/E ratio this period.

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

Max: 85.34
Q3: 43.46
Median: 26.69
Q1: 13.30
Min: 0.07
NTRA: --

TECH

Pharmaceuticals, Biotechnology & Life Sciences industry group

62.74

Max: 85.34
TECH: 62.74
Q3: 43.46
Median: 26.69
Q1: 13.30
Min: 0.07

Natera (NTRA) vs. Bio-Techne (TECH): NTRA does not report P/E ratio, so it has no value marker; TECH is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

P/S Ratio (TTM)

On P/S ratio, both Natera (NTRA) at 15.49 and Bio-Techne (TECH) at 9.31 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

15.49

Max: 58.18
Q3: 25.77
NTRA: 15.49
Median: 7.30
Q1: 3.01
Min: 0.01

TECH

Pharmaceuticals, Biotechnology & Life Sciences industry group

9.31

Max: 58.18
Q3: 25.77
TECH: 9.31
Median: 7.30
Q1: 3.01
Min: 0.01

Natera (NTRA) vs. Bio-Techne (TECH): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Bio-Techne (TECH) at 5.28 sits near its industry’s typical P/B ratio, while Natera (NTRA) at 23.99 prices above its benchmark range — NTRA looks rich relative to book.

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

23.99

NTRA: 23.99
Max: 13.53
Q3: 6.54
Median: 3.25
Q1: 1.69
Min: -5.59

TECH

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.28

Max: 13.53
Q3: 6.54
TECH: 5.28
Median: 3.25
Q1: 1.69
Min: -5.59

Natera (NTRA) vs. Bio-Techne (TECH): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Natera (NTRA) and Bio-Techne (TECH)
Metric	NTRA	TECH
P/E Ratio (TTM)	--	62.74
P/S Ratio (TTM)	15.49	9.31
P/B Ratio (MRQ)	23.99	5.28
Free Cash Flow Yield (TTM)	0.19%	2.39%