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NTRA vs. RVMD: Natera vs. Revolution Medicines Stock Comparison

How do Natera (NTRA) and Revolution Medicines (RVMD) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Natera (NTRA) and Revolution Medicines (RVMD) are both classified in the Biotechnology sub-industry within the broader Biotechnology industry, placing them in the closest GICS peer bucket.

Company profile comparison for Natera (NTRA) and Revolution Medicines (RVMD)
Profile ItemNTRARVMD
NameNatera, Inc.Revolution Medicines, Inc.
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyBiotechnology
GICS Sub-IndustryBiotechnologyBiotechnology
Market Capitalization45.05 billion USD41.59 billion USD
CurrencyUSDUSD
ExchangeNasdaqNasdaq
Listing DateJuly 1, 2015February 13, 2020
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

NTRA
RVMD
GSPC
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Natera (NTRA) vs. Revolution Medicines (RVMD), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Natera (NTRA) and Revolution Medicines (RVMD). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Natera (NTRA) and Revolution Medicines (RVMD). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Natera (NTRA) and Revolution Medicines (RVMD)
MetricNTRARVMD
Total Return (1Y)61.03%224.80%
Total Return (3Y, Annualized)92.02%114.71%
Total Return (5Y, Annualized)23.20%43.47%

Risk Profile

Drawdown History

NTRA
RVMD
GSPC
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Natera (NTRA) vs. Revolution Medicines (RVMD), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Natera (NTRA) and Revolution Medicines (RVMD). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Natera (NTRA) and Revolution Medicines (RVMD)
MetricNTRARVMD
Volatility (1Y, Annualized)52.30%68.29%
Beta (5Y)1.581.42
Max Drawdown (5Y)-75.72%-55.71%
Avg. Volume (3M)1.68M2.06M

Risk-Adjusted Performance

Risk-Return Positioning

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NTRA and RVMD are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Natera (NTRA) and Revolution Medicines (RVMD)
MetricNTRARVMD
Sharpe Ratio (1Y)1.093.23
Sortino Ratio (1Y)1.636.92

Profitability

ROE (TTM)

Both Natera (NTRA) at -10.55% and Revolution Medicines (RVMD) at -93.56% report negative ROE values. Negative ROE can reflect losses or negative shareholders’ equity, so both readings need extra context.

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

-10.55%

Max
109.18%
Q3
6.23%
NTRA
-10.55%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

-93.56%

Max
109.18%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
RVMD
-93.56%
Min
-167.77%
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Natera (NTRA) vs. Revolution Medicines (RVMD): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Natera (NTRA) reports a negative net margin of -5.66%, usually indicating a net loss over the period. Meanwhile Revolution Medicines (RVMD) reports 0.00%, ranking against industry peers normally.

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

-5.66%

Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
NTRA
-5.66%
Min
-17.05%

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

Max
18.05%
Q3
4.78%
RVMD
0.00%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Natera (NTRA) vs. Revolution Medicines (RVMD): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Natera (NTRA) at -7.64% and Revolution Medicines (RVMD) at -188.88% report negative operating margin values, usually indicating operating losses over the period.

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

-7.64%

Max
83.12%
Q3
14.77%
Median
0.00%
NTRA
-7.64%
Q1
-78.82%
Min
-207.40%

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

-188.88%

Max
83.12%
Q3
14.77%
Median
0.00%
Q1
-78.82%
RVMD
-188.88%
Min
-207.40%
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Natera (NTRA) vs. Revolution Medicines (RVMD): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Natera (NTRA) and Revolution Medicines (RVMD)
MetricNTRARVMD
ROE (TTM)-10.55%-93.56%
ROA (TTM)-6.79%-32.13%
Net Margin (TTM)-5.66%0.00%
Operating Margin (TTM)-7.64%-188.88%
Gross Margin (TTM)65.14%0.00%

Growth

Revenue Growth

Only one side can be read here: Natera (NTRA) reports revenue growth of 35.90%, ranked against its industry; Revolution Medicines (RVMD) has no revenue growth figure this period.

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Natera (NTRA) vs. Revolution Medicines (RVMD): A comparison of their Revenue Growth across different time periods.

EPS Growth

Neither Natera (NTRA) nor Revolution Medicines (RVMD) reports a EPS growth value for this period, so a direct comparison isn't possible.

Growth Metrics

Growth metrics for Natera (NTRA) and Revolution Medicines (RVMD)
MetricNTRARVMD
Revenue Growth (YoY)35.90%--
Revenue Growth (3Y CAGR)41.14%--
EPS Growth (YoY)----
EPS Growth (3Y CAGR)----

Financial Strength

Current Ratio (MRQ)

Both Natera (NTRA) at 2.81 and Revolution Medicines (RVMD) at 8.36 carry current ratio within their industries’ typical mid-ranges, suggesting balanced short-term liquidity relative to peers.

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.81

Max
25.13
Q3
12.13
Median
5.52
NTRA
2.81
Q1
2.47
Min
0.10

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

8.36

Max
25.13
Q3
12.13
RVMD
8.36
Median
5.52
Q1
2.47
Min
0.10
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Natera (NTRA) vs. Revolution Medicines (RVMD): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Both Natera (NTRA) at 0.13 and Revolution Medicines (RVMD) at 0.50 fund their balance sheets with roughly industry-typical debt-to-equity mixes.

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.13

Max
1.42
Q3
0.65
Median
0.15
NTRA
0.13
Q1
0.02
Min
0.00

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.50

Max
1.42
Q3
0.65
RVMD
0.50
Median
0.15
Q1
0.02
Min
0.00
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Natera (NTRA) vs. Revolution Medicines (RVMD): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Natera (NTRA) and Revolution Medicines (RVMD)
MetricNTRARVMD
Current Ratio (MRQ)2.818.36
Debt / Equity (MRQ)0.130.50
Net Debt / EBITDA----

Dividends

Dividend Yield (TTM)

Neither Natera (NTRA) nor Revolution Medicines (RVMD) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

NTRA
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

RVMD
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Natera (NTRA) vs. Revolution Medicines (RVMD): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Neither Natera (NTRA) nor Revolution Medicines (RVMD) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

NTRA
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

RVMD
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Natera (NTRA) vs. Revolution Medicines (RVMD): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Natera (NTRA) and Revolution Medicines (RVMD)
MetricNTRARVMD
Dividend Yield (TTM)0.00%0.00%
Dividend Payout Ratio (TTM)0.00%0.00%

Valuation

P/E Ratio (TTM)

Neither Natera (NTRA) nor Revolution Medicines (RVMD) reports a P/E ratio value for this period, so a direct comparison isn’t possible.

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
NTRA
--

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
RVMD
--
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Natera (NTRA) vs. Revolution Medicines (RVMD): Neither stock reports P/E ratio, so the chart shows available benchmark boxes without value markers.

P/S Ratio (TTM)

Natera (NTRA) at 15.49 prices around its industry’s typical P/S ratio, while Revolution Medicines (RVMD) at 210.51 clears its benchmark range — RVMD looks notably rich on sales.

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

15.49

Max
58.18
Q3
25.77
NTRA
15.49
Median
7.30
Q1
3.01
Min
0.01

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

210.51

RVMD
210.51
Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
Min
0.01
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Natera (NTRA) vs. Revolution Medicines (RVMD): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Measured against book value, both Natera (NTRA) at 23.99 and Revolution Medicines (RVMD) at 17.31 look expensive — each P/B ratio sits above its industry’s benchmark range.

NTRA

Pharmaceuticals, Biotechnology & Life Sciences industry group

23.99

NTRA
23.99
Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

RVMD

Pharmaceuticals, Biotechnology & Life Sciences industry group

17.31

RVMD
17.31
Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
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Natera (NTRA) vs. Revolution Medicines (RVMD): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Natera (NTRA) and Revolution Medicines (RVMD)
MetricNTRARVMD
P/E Ratio (TTM)----
P/S Ratio (TTM)15.49210.51
P/B Ratio (MRQ)23.9917.31
Free Cash Flow Yield (TTM)0.19%-2.13%