GSK vs. TEM: GSK vs. Tempus AI Stock Comparison
How do GSK (GSK) and Tempus AI (TEM) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.
Company Profile
GSK (GSK) and Tempus AI (TEM) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but GSK is classified in Pharmaceuticals while TEM is classified in Life Sciences Tools & Services.
GSK (GSK) carries decades of public-market history since March 28, 1980, while Tempus AI (TEM) listed on June 14, 2024 — long-window comparisons have far more historical data on the GSK side.
Tempus AI (TEM) trades as ordinary local shares, while GSK (GSK) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.
| Profile Item | GSK | TEM |
|---|---|---|
| Name | GSK plc ADR | Tempus AI Inc Class A Common Stock |
| Country/Region | United Kingdom | United States |
| GICS Sector | Health Care | Health Care |
| GICS Industry Group | Pharmaceuticals, Biotechnology & Life Sciences | Pharmaceuticals, Biotechnology & Life Sciences |
| GICS Industry | Pharmaceuticals | Life Sciences Tools & Services |
| GICS Sub-Industry | Pharmaceuticals | Life Sciences Tools & Services |
| Market Capitalization | 100.88 billion USD | 13.87 billion USD |
| Currency | USD | USD |
| Exchange | NYSE | Nasdaq |
| Listing Date | March 28, 1980 | June 14, 2024 |
| Security Type | ADR | Common Stock |
Price Performance
Cumulative Growth
Trailing Returns
Calendar-Year Returns
Performance Metrics
| Metric | GSK | TEM |
|---|---|---|
| Total Return (1Y) | 13.73% | 16.25% |
| Total Return (3Y, Annualized) | 18.65% | -- |
| Total Return (5Y, Annualized) | 7.97% | -- |
Risk Profile
Drawdown History
Return Distribution
Risk Metrics
Tempus AI (TEM) has a highly aggressive beta of 3.34, indicating much higher sensitivity to broad-market moves, while GSK (GSK) is defensive at 0.31 and tends to be less market-sensitive — a wide gap in beta profiles.
| Metric | GSK | TEM |
|---|---|---|
| Volatility (1Y, Annualized) | 26.25% | 76.08% |
| Beta (5Y) | 0.31 | 3.34 |
| Max Drawdown (5Y) | -37.63% | -59.76% |
| Avg. Volume (3M) | 4.05M | 7.20M |
Risk-Adjusted Performance
Risk-Return Positioning
Risk-Adjusted Metrics
| Metric | GSK | TEM |
|---|---|---|
| Sharpe Ratio (1Y) | 0.36 | 0.16 |
| Sortino Ratio (1Y) | 0.56 | 0.26 |
Profitability
ROE (TTM)
Tempus AI (TEM) reports a negative ROE of -37.55%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile GSK (GSK) reports 28.27%, ranking against industry peers normally.
GSK
Pharmaceuticals, Biotechnology & Life Sciences industry group
28.27%
- Max
- 109.18%
- GSK
- 28.27%
- Q3
- 6.23%
- Median
- -26.66%
- Q1
- -64.05%
- Min
- -167.77%
TEM
Pharmaceuticals, Biotechnology & Life Sciences industry group
-37.55%
- Max
- 109.18%
- Q3
- 6.23%
- Median
- -26.66%
- TEM
- -37.55%
- Q1
- -64.05%
- Min
- -167.77%
Net Margin (TTM)
Tempus AI (TEM) reports a negative net margin of -12.54%, usually indicating a net loss over the period. Meanwhile GSK (GSK) reports 12.97%, ranking against industry peers normally.
GSK
Pharmaceuticals, Biotechnology & Life Sciences industry group
12.97%
- Max
- 18.05%
- GSK
- 12.97%
- Q3
- 4.78%
- Median
- 0.00%
- Q1
- -4.14%
- Min
- -17.05%
TEM
Pharmaceuticals, Biotechnology & Life Sciences industry group
-12.54%
- Max
- 18.05%
- Q3
- 4.78%
- Median
- 0.00%
- Q1
- -4.14%
- TEM
- -12.54%
- Min
- -17.05%
Operating Margin (TTM)
Tempus AI (TEM) reports a negative operating margin of -13.82%, usually indicating that operating costs exceeded revenue at the operating-income line. Meanwhile GSK (GSK) reports 32.14%, ranking against industry peers normally.
GSK
Pharmaceuticals, Biotechnology & Life Sciences industry group
32.14%
- Max
- 83.12%
- GSK
- 32.14%
- Q3
- 14.77%
- Median
- 0.00%
- Q1
- -78.82%
- Min
- -207.40%
TEM
Pharmaceuticals, Biotechnology & Life Sciences industry group
-13.82%
- Max
- 83.12%
- Q3
- 14.77%
- Median
- 0.00%
- TEM
- -13.82%
- Q1
- -78.82%
- Min
- -207.40%
Profitability Metrics
| Metric | GSK | TEM |
|---|---|---|
| ROE (TTM) | 28.27% | -37.55% |
| ROA (TTM) | 9.24% | -7.36% |
| Net Margin (TTM) | 12.97% | -12.54% |
| Operating Margin (TTM) | 32.14% | -13.82% |
| Gross Margin (TTM) | 73.79% | 64.46% |
Growth
Revenue Growth
Tempus AI (TEM) at 83.41% sits in the top revenue growth quartile, while GSK (GSK) at 4.11% is closer to the peer norm — faster top-line expansion for TEM.
EPS Growth
Only one side can be read here: GSK (GSK) reports EPS growth of 123.15%, ranked against its industry; Tempus AI (TEM) has no EPS growth figure this period.
Growth Metrics
| Metric | GSK | TEM |
|---|---|---|
| Revenue Growth (YoY) | 4.11% | 83.41% |
| Revenue Growth (3Y CAGR) | 3.66% | 58.29% |
| EPS Growth (YoY) | 123.15% | -- |
| EPS Growth (3Y CAGR) | -27.63% | -- |
Financial Strength
Current Ratio (MRQ)
Tempus AI (TEM) at 2.61 keeps current ratio within its industry’s typical mid-range, while GSK (GSK) at 0.86 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for GSK.
GSK
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.86
- Max
- 25.13
- Q3
- 12.13
- Median
- 5.52
- Q1
- 2.47
- GSK
- 0.86
- Min
- 0.10
TEM
Pharmaceuticals, Biotechnology & Life Sciences industry group
2.61
- Max
- 25.13
- Q3
- 12.13
- Median
- 5.52
- TEM
- 2.61
- Q1
- 2.47
- Min
- 0.10
Debt / Equity (MRQ)
Both balance sheets lean debt-heavy versus peers, but TEM is more stretched: GSK (GSK) at 1.30 sits in the higher-leverage quartile and Tempus AI (TEM) at 2.86 is above its industry benchmark range.
GSK
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.30
- Max
- 1.42
- GSK
- 1.30
- Q3
- 0.65
- Median
- 0.15
- Q1
- 0.02
- Min
- 0.00
TEM
Pharmaceuticals, Biotechnology & Life Sciences industry group
2.86
- TEM
- 2.86
- Max
- 1.42
- Q3
- 0.65
- Median
- 0.15
- Q1
- 0.02
- Min
- 0.00
Financial Strength Metrics
| Metric | GSK | TEM |
|---|---|---|
| Current Ratio (MRQ) | 0.86 | 2.61 |
| Debt / Equity (MRQ) | 1.30 | 2.86 |
| Net Debt / EBITDA | 1.88 | -- |
Dividends
Dividend Yield (TTM)
Tempus AI (TEM) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile GSK (GSK) reports a yield of 1.57%, ranking against industry peers normally.
GSK
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.57%
- GSK
- 1.57%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
TEM
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.00%
- TEM
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Payout Ratio (TTM)
Tempus AI (TEM) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile GSK (GSK) reports a payout of 63.33%, ranking against industry peers normally.
GSK
Pharmaceuticals, Biotechnology & Life Sciences industry group
63.33%
- GSK
- 63.33%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
TEM
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.00%
- TEM
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Metrics
| Metric | GSK | TEM |
|---|---|---|
| Dividend Yield (TTM) | 1.57% | 0.00% |
| Dividend Payout Ratio (TTM) | 63.33% | 0.00% |
Valuation
P/E Ratio (TTM)
An earnings multiple is available for just one side: GSK (GSK) trades at 17.54 times trailing earnings, ranked against its peers, while Tempus AI (TEM) has no P/E ratio this period.
GSK
Pharmaceuticals, Biotechnology & Life Sciences industry group
17.54
- Max
- 85.34
- Q3
- 43.46
- Median
- 26.69
- GSK
- 17.54
- Q1
- 13.30
- Min
- 0.07
TEM
Pharmaceuticals, Biotechnology & Life Sciences industry group
--
- Max
- 85.34
- Q3
- 43.46
- Median
- 26.69
- Q1
- 13.30
- Min
- 0.07
- TEM
- --
P/S Ratio (TTM)
GSK (GSK) at 3.01 sits in the cheaper P/S ratio quartile while Tempus AI (TEM) at 9.19 prices around its industry’s middle — GSK costs less per dollar of sales, though read it alongside growth and margins.
GSK
Pharmaceuticals, Biotechnology & Life Sciences industry group
3.01
- Max
- 58.18
- Q3
- 25.77
- Median
- 7.30
- Q1
- 3.01
- GSK
- 3.01
- Min
- 0.01
TEM
Pharmaceuticals, Biotechnology & Life Sciences industry group
9.19
- Max
- 58.18
- Q3
- 25.77
- TEM
- 9.19
- Median
- 7.30
- Q1
- 3.01
- Min
- 0.01
P/B Ratio (MRQ)
GSK (GSK) at 4.02 sits near its industry’s typical P/B ratio, while Tempus AI (TEM) at 27.66 prices above its benchmark range — TEM looks rich relative to book.
GSK
Pharmaceuticals, Biotechnology & Life Sciences industry group
4.02
- Max
- 13.53
- Q3
- 6.54
- GSK
- 4.02
- Median
- 3.25
- Q1
- 1.69
- Min
- -5.59
TEM
Pharmaceuticals, Biotechnology & Life Sciences industry group
27.66
- TEM
- 27.66
- Max
- 13.53
- Q3
- 6.54
- Median
- 3.25
- Q1
- 1.69
- Min
- -5.59
Valuation Metrics
| Metric | GSK | TEM |
|---|---|---|
| P/E Ratio (TTM) | 17.54 | -- |
| P/S Ratio (TTM) | 3.01 | 9.19 |
| P/B Ratio (MRQ) | 4.02 | 27.66 |
| Free Cash Flow Yield (TTM) | 5.28% | 0.30% |