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GSK vs. RGEN: GSK vs. Repligen Stock Comparison

How do GSK (GSK) and Repligen (RGEN) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

GSK (GSK) and Repligen (RGEN) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but GSK is classified in Pharmaceuticals while RGEN is classified in Life Sciences Tools & Services.

Repligen (RGEN) trades as ordinary local shares, while GSK (GSK) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.

Company profile comparison for GSK (GSK) and Repligen (RGEN)
Profile ItemGSKRGEN
NameGSK plc ADRRepligen Corporation
Country/RegionUnited KingdomUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryPharmaceuticalsLife Sciences Tools & Services
GICS Sub-IndustryPharmaceuticalsLife Sciences Tools & Services
Market Capitalization100.88 billion USD11.09 billion USD
CurrencyUSDUSD
ExchangeNYSENasdaq
Listing DateMarch 28, 1980April 29, 1986
Security TypeADRCommon Stock

Price Performance

Cumulative Growth

GSK
RGEN
GSPC
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GSK (GSK) vs. Repligen (RGEN), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for GSK (GSK) and Repligen (RGEN). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for GSK (GSK) and Repligen (RGEN). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for GSK (GSK) and Repligen (RGEN)
MetricGSKRGEN
Total Return (1Y)13.73%23.28%
Total Return (3Y, Annualized)18.65%6.20%
Total Return (5Y, Annualized)7.97%-8.41%

Risk Profile

Drawdown History

GSK
RGEN
GSPC
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GSK (GSK) vs. Repligen (RGEN), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for GSK (GSK) and Repligen (RGEN). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for GSK (GSK) and Repligen (RGEN)
MetricGSKRGEN
Volatility (1Y, Annualized)26.25%46.73%
Beta (5Y)0.311.11
Max Drawdown (5Y)-37.63%-64.67%
Avg. Volume (3M)4.05M1.18M

Risk-Adjusted Performance

Risk-Return Positioning

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GSK and RGEN are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for GSK (GSK) and Repligen (RGEN)
MetricGSKRGEN
Sharpe Ratio (1Y)0.360.41
Sortino Ratio (1Y)0.560.60

Profitability

ROE (TTM)

Repligen (RGEN) reports a negative ROE of -0.57%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile GSK (GSK) reports 28.27%, ranking against industry peers normally.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

28.27%

Max
109.18%
GSK
28.27%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

-0.57%

Max
109.18%
Q3
6.23%
RGEN
-0.57%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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GSK (GSK) vs. Repligen (RGEN): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Repligen (RGEN) reports a negative net margin of -1.47%, usually indicating a net loss over the period. Meanwhile GSK (GSK) reports 12.97%, ranking against industry peers normally.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

12.97%

Max
18.05%
GSK
12.97%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

-1.47%

Max
18.05%
Q3
4.78%
Median
0.00%
RGEN
-1.47%
Q1
-4.14%
Min
-17.05%
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GSK (GSK) vs. Repligen (RGEN): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

GSK (GSK) at 32.14% operates in the top operating margin quartile, ahead of Repligen (RGEN) at 6.19%, which runs around its industry’s norm.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

32.14%

Max
83.12%
GSK
32.14%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.19%

Max
83.12%
Q3
14.77%
RGEN
6.19%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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GSK (GSK) vs. Repligen (RGEN): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for GSK (GSK) and Repligen (RGEN)
MetricGSKRGEN
ROE (TTM)28.27%-0.57%
ROA (TTM)9.24%1.40%
Net Margin (TTM)12.97%-1.47%
Operating Margin (TTM)32.14%6.19%
Gross Margin (TTM)73.79%53.77%

Growth

Revenue Growth

Both GSK (GSK) at 4.11% and Repligen (RGEN) at 16.36% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

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GSK (GSK) vs. Repligen (RGEN): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: GSK (GSK) reports EPS growth of 123.15%, ranked against its industry; Repligen (RGEN) has no EPS growth figure this period.

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GSK (GSK) vs. Repligen (RGEN): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for GSK (GSK) and Repligen (RGEN)
MetricGSKRGEN
Revenue Growth (YoY)4.11%16.36%
Revenue Growth (3Y CAGR)3.66%-2.70%
EPS Growth (YoY)123.15%--
EPS Growth (3Y CAGR)-27.63%-35.73%

Financial Strength

Current Ratio (MRQ)

Repligen (RGEN) at 9.88 keeps current ratio within its industry’s typical mid-range, while GSK (GSK) at 0.86 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for GSK.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.86

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
GSK
0.86
Min
0.10

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

9.88

Max
25.13
Q3
12.13
RGEN
9.88
Median
5.52
Q1
2.47
Min
0.10
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GSK (GSK) vs. Repligen (RGEN): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Repligen (RGEN) at 0.33 carries an industry-typical debt-to-equity mix, while GSK (GSK) at 1.30 uses more debt funding than most peers.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.30

Max
1.42
GSK
1.30
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.33

Max
1.42
Q3
0.65
RGEN
0.33
Median
0.15
Q1
0.02
Min
0.00
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GSK (GSK) vs. Repligen (RGEN): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for GSK (GSK) and Repligen (RGEN)
MetricGSKRGEN
Current Ratio (MRQ)0.869.88
Debt / Equity (MRQ)1.300.33
Net Debt / EBITDA1.88-1.19

Dividends

Dividend Yield (TTM)

Repligen (RGEN) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile GSK (GSK) reports a yield of 1.57%, ranking against industry peers normally.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.57%

GSK
1.57%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

RGEN
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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GSK (GSK) vs. Repligen (RGEN): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Repligen (RGEN) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile GSK (GSK) reports a payout of 63.33%, ranking against industry peers normally.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

63.33%

GSK
63.33%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

RGEN
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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GSK (GSK) vs. Repligen (RGEN): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for GSK (GSK) and Repligen (RGEN)
MetricGSKRGEN
Dividend Yield (TTM)1.57%0.00%
Dividend Payout Ratio (TTM)63.33%0.00%

Valuation

P/E Ratio (TTM)

An earnings multiple is available for just one side: GSK (GSK) trades at 17.54 times trailing earnings, ranked against its peers, while Repligen (RGEN) has no P/E ratio this period.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

17.54

Max
85.34
Q3
43.46
Median
26.69
GSK
17.54
Q1
13.30
Min
0.07

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
RGEN
--
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GSK (GSK) vs. Repligen (RGEN): RGEN does not report P/E ratio, so it has no value marker; GSK is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

P/S Ratio (TTM)

GSK (GSK) at 3.01 sits in the cheaper P/S ratio quartile while Repligen (RGEN) at 13.77 prices around its industry’s middle — GSK costs less per dollar of sales, though read it alongside growth and margins.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.01

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
GSK
3.01
Min
0.01

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

13.77

Max
58.18
Q3
25.77
RGEN
13.77
Median
7.30
Q1
3.01
Min
0.01
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GSK (GSK) vs. Repligen (RGEN): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

On P/B ratio, both GSK (GSK) at 4.02 and Repligen (RGEN) at 4.70 are valued close to their industries’ norm against book — neither stands out from peers.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.02

Max
13.53
Q3
6.54
GSK
4.02
Median
3.25
Q1
1.69
Min
-5.59

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.70

Max
13.53
Q3
6.54
RGEN
4.70
Median
3.25
Q1
1.69
Min
-5.59
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GSK (GSK) vs. Repligen (RGEN): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for GSK (GSK) and Repligen (RGEN)
MetricGSKRGEN
P/E Ratio (TTM)17.54--
P/S Ratio (TTM)3.0113.77
P/B Ratio (MRQ)4.024.70
Free Cash Flow Yield (TTM)5.28%1.01%