ABBV vs. RGEN: AbbVie vs. Repligen Stock Comparison

November 11, 2026

How do AbbVie (ABBV) and Repligen (RGEN) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

AbbVie (ABBV) and Repligen (RGEN) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but ABBV is classified in Biotechnology while RGEN is classified in Life Sciences Tools & Services.

Company profile comparison for AbbVie (ABBV) and Repligen (RGEN)
Profile Item	ABBV	RGEN
Name	AbbVie Inc.	Repligen Corporation
Country/Region	United States	United States
GICS Sector	Health Care	Health Care
GICS Industry Group	Pharmaceuticals, Biotechnology & Life Sciences	Pharmaceuticals, Biotechnology & Life Sciences
GICS Industry	Biotechnology	Life Sciences Tools & Services
GICS Sub-Industry	Biotechnology	Life Sciences Tools & Services
Market Capitalization	514.92 billion USD	11.09 billion USD
Currency	USD	USD
Exchange	NYSE	Nasdaq
Listing Date	January 2, 2013	April 29, 1986
Security Type	Common Stock	Common Stock

Price Performance

Cumulative Growth

ABBV

RGEN

GSPC

AbbVie (ABBV) vs. Repligen (RGEN), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for AbbVie (ABBV) and Repligen (RGEN). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for AbbVie (ABBV) and Repligen (RGEN). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for AbbVie (ABBV) and Repligen (RGEN)
Metric	ABBV	RGEN
Total Return (1Y)	37.33%	23.28%
Total Return (3Y, Annualized)	32.74%	6.20%
Total Return (5Y, Annualized)	24.73%	-8.41%

Risk Profile

Drawdown History

ABBV

RGEN

GSPC

AbbVie (ABBV) vs. Repligen (RGEN), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for AbbVie (ABBV) and Repligen (RGEN). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for AbbVie (ABBV) and Repligen (RGEN)
Metric	ABBV	RGEN
Volatility (1Y, Annualized)	25.65%	46.73%
Beta (5Y)	0.21	1.11
Max Drawdown (5Y)	-21.92%	-64.67%
Avg. Volume (3M)	4.76M	1.18M

Risk-Adjusted Performance

Risk-Return Positioning

ABBV and RGEN are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for AbbVie (ABBV) and Repligen (RGEN)
Metric	ABBV	RGEN
Sharpe Ratio (1Y)	1.29	0.41
Sortino Ratio (1Y)	2.02	0.60

Profitability

ROE (TTM)

AbbVie (ABBV) has no ROE value reported for this period; Repligen (RGEN) reports a negative figure of -0.57%, which needs context because negative ROE can reflect losses or negative shareholders’ equity.

ABBV

Pharmaceuticals, Biotechnology & Life Sciences industry group

Max: 109.18%
Q3: 6.23%
Median: -26.66%
Q1: -64.05%
Min: -167.77%
ABBV: --

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

-0.57%

Max: 109.18%
Q3: 6.23%
RGEN: -0.57%
Median: -26.66%
Q1: -64.05%
Min: -167.77%

AbbVie (ABBV) vs. Repligen (RGEN): ABBV does not report ROE, so it has no value marker; RGEN is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

Net Margin (TTM)

Repligen (RGEN) reports a negative net margin of -1.47%, usually indicating a net loss over the period. Meanwhile AbbVie (ABBV) reports 15.67%, ranking against industry peers normally.

ABBV

Pharmaceuticals, Biotechnology & Life Sciences industry group

15.67%

Max: 18.05%
ABBV: 15.67%
Q3: 4.78%
Median: 0.00%
Q1: -4.14%
Min: -17.05%

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

-1.47%

Max: 18.05%
Q3: 4.78%
Median: 0.00%
RGEN: -1.47%
Q1: -4.14%
Min: -17.05%

AbbVie (ABBV) vs. Repligen (RGEN): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

AbbVie (ABBV) at 39.59% operates in the top operating margin quartile, ahead of Repligen (RGEN) at 6.19%, which runs around its industry’s norm.

ABBV

Pharmaceuticals, Biotechnology & Life Sciences industry group

39.59%

Max: 83.12%
ABBV: 39.59%
Q3: 14.77%
Median: 0.00%
Q1: -78.82%
Min: -207.40%

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.19%

Max: 83.12%
Q3: 14.77%
RGEN: 6.19%
Median: 0.00%
Q1: -78.82%
Min: -207.40%

AbbVie (ABBV) vs. Repligen (RGEN): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for AbbVie (ABBV) and Repligen (RGEN)
Metric	ABBV	RGEN
ROE (TTM)	--	-0.57%
ROA (TTM)	10.74%	1.40%
Net Margin (TTM)	15.67%	-1.47%
Operating Margin (TTM)	39.59%	6.19%
Gross Margin (TTM)	73.72%	53.77%

Growth

Revenue Growth

Both AbbVie (ABBV) at 8.57% and Repligen (RGEN) at 16.36% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

AbbVie (ABBV) vs. Repligen (RGEN): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: AbbVie (ABBV) reports EPS growth of -0.84%, ranked against its industry; Repligen (RGEN) has no EPS growth figure this period.

AbbVie (ABBV) vs. Repligen (RGEN): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for AbbVie (ABBV) and Repligen (RGEN)
Metric	ABBV	RGEN
Revenue Growth (YoY)	8.57%	16.36%
Revenue Growth (3Y CAGR)	1.75%	-2.70%
EPS Growth (YoY)	-0.84%	--
EPS Growth (3Y CAGR)	-29.03%	-35.73%

Financial Strength

Current Ratio (MRQ)

Repligen (RGEN) at 9.88 keeps current ratio within its industry’s typical mid-range, while AbbVie (ABBV) at 0.87 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for ABBV.

ABBV

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.87

Max: 25.13
Q3: 12.13
Median: 5.52
Q1: 2.47
ABBV: 0.87
Min: 0.10

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

9.88

Max: 25.13
Q3: 12.13
RGEN: 9.88
Median: 5.52
Q1: 2.47
Min: 0.10

AbbVie (ABBV) vs. Repligen (RGEN): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Only one side’s leverage can be read here: Repligen (RGEN) carries debt-to-equity ratio of 0.33 against its industry range, while AbbVie (ABBV) reports no figure this period.

ABBV

Pharmaceuticals, Biotechnology & Life Sciences industry group

Max: 1.42
Q3: 0.65
Median: 0.15
Q1: 0.02
Min: 0.00
ABBV: --

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.33

Max: 1.42
Q3: 0.65
RGEN: 0.33
Median: 0.15
Q1: 0.02
Min: 0.00

AbbVie (ABBV) vs. Repligen (RGEN): ABBV does not report debt-to-equity ratio, so it has no value marker; RGEN is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

Financial Strength Metrics

Financial strength metrics for AbbVie (ABBV) and Repligen (RGEN)
Metric	ABBV	RGEN
Current Ratio (MRQ)	0.87	9.88
Debt / Equity (MRQ)	--	0.33
Net Debt / EBITDA	2.21	-1.19

Dividends

Dividend Yield (TTM)

Repligen (RGEN) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile AbbVie (ABBV) reports a yield of 2.40%, ranking against industry peers normally.

ABBV

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.40%

ABBV: 2.40%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

RGEN: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

AbbVie (ABBV) vs. Repligen (RGEN): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

AbbVie (ABBV) reports payout ratio above 100% at 117.35%, meaning dividends exceeded current-period earnings; Repligen (RGEN) pays no dividend (payout 0.00%).

ABBV

Pharmaceuticals, Biotechnology & Life Sciences industry group

117.35%

ABBV: 117.35%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

RGEN: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

AbbVie (ABBV) vs. Repligen (RGEN): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for AbbVie (ABBV) and Repligen (RGEN)
Metric	ABBV	RGEN
Dividend Yield (TTM)	2.40%	0.00%
Dividend Payout Ratio (TTM)	117.35%	0.00%

Valuation

P/E Ratio (TTM)

An earnings multiple is available for just one side: AbbVie (ABBV) trades at 50.05 times trailing earnings, ranked against its peers, while Repligen (RGEN) has no P/E ratio this period.

ABBV

Pharmaceuticals, Biotechnology & Life Sciences industry group

50.05

Max: 85.34
ABBV: 50.05
Q3: 43.46
Median: 26.69
Q1: 13.30
Min: 0.07

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

Max: 85.34
Q3: 43.46
Median: 26.69
Q1: 13.30
Min: 0.07
RGEN: --

AbbVie (ABBV) vs. Repligen (RGEN): RGEN does not report P/E ratio, so it has no value marker; ABBV is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

P/S Ratio (TTM)

On P/S ratio, both AbbVie (ABBV) at 7.80 and Repligen (RGEN) at 13.77 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

ABBV

Pharmaceuticals, Biotechnology & Life Sciences industry group

7.80

Max: 58.18
Q3: 25.77
ABBV: 7.80
Median: 7.30
Q1: 3.01
Min: 0.01

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

13.77

Max: 58.18
Q3: 25.77
RGEN: 13.77
Median: 7.30
Q1: 3.01
Min: 0.01

AbbVie (ABBV) vs. Repligen (RGEN): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

AbbVie (ABBV) reports a negative P/B ratio of -112.34, meaning negative book equity — the multiple itself is not meaningful for valuation. Meanwhile Repligen (RGEN) reports 4.70, ranking against industry peers normally.

ABBV

Pharmaceuticals, Biotechnology & Life Sciences industry group

-112.34

Max: 13.53
Q3: 6.54
Median: 3.25
Q1: 1.69
Min: -5.59
ABBV: -112.34

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.70

Max: 13.53
Q3: 6.54
RGEN: 4.70
Median: 3.25
Q1: 1.69
Min: -5.59

AbbVie (ABBV) vs. Repligen (RGEN): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for AbbVie (ABBV) and Repligen (RGEN)
Metric	ABBV	RGEN
P/E Ratio (TTM)	50.05	--
P/S Ratio (TTM)	7.80	13.77
P/B Ratio (MRQ)	-112.34	4.70
Free Cash Flow Yield (TTM)	3.44%	1.01%