GH vs. MDLN: Guardant Health vs. Medline Stock Comparison
How do Guardant Health (GH) and Medline (MDLN) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.
Company Profile
Guardant Health (GH) and Medline (MDLN) both fall under the Health Care Equipment & Services industry group, but GH is classified in Health Care Providers & Services while MDLN is classified in Health Care Equipment & Supplies.
Guardant Health (GH) has been public since October 4, 2018 with a meaningfully longer listed history, while Medline (MDLN) only listed on December 17, 2025 — long-window metrics on the MDLN side should be interpreted with caution.
| Profile Item | GH | MDLN |
|---|---|---|
| Name | Guardant Health, Inc. | Medline Inc. Class A Common Stock |
| Country/Region | United States | United States |
| GICS Sector | Health Care | Health Care |
| GICS Industry Group | Health Care Equipment & Services | Health Care Equipment & Services |
| GICS Industry | Health Care Providers & Services | Health Care Equipment & Supplies |
| GICS Sub-Industry | Health Care Services | Health Care Supplies |
| Market Capitalization | 20.41 billion USD | 52.17 billion USD |
| Currency | USD | USD |
| Exchange | Nasdaq | Nasdaq |
| Listing Date | October 4, 2018 | December 17, 2025 |
| Security Type | Common Stock | Common Stock |
Price Performance
Cumulative Growth
Trailing Returns
Calendar-Year Returns
Performance Metrics
| Metric | GH | MDLN |
|---|---|---|
| Total Return (1Y) | 66.53% | -- |
| Total Return (3Y, Annualized) | 92.76% | -- |
| Total Return (5Y, Annualized) | 8.36% | -- |
Risk Profile
Drawdown History
Return Distribution
Risk Metrics
Medline (MDLN) reports a negative beta of -0.93, suggesting inverse market sensitivity over the measurement window. That is uncommon for ordinary equities and can reflect commodity-linked or hedge-like exposure, but it can also come from statistical noise. Guardant Health (GH) has a non-negative beta of 1.69.
| Metric | GH | MDLN |
|---|---|---|
| Volatility (1Y, Annualized) | 53.23% | 47.93% |
| Beta (5Y) | 1.69 | -0.93 |
| Max Drawdown (5Y) | -85.09% | -36.71% |
| Avg. Volume (3M) | 1.97M | 8.63M |
Risk-Adjusted Performance
Risk-Return Positioning
Both GH and MDLN need 1-year volatility and 1-year return to plot risk-return positioning.
Risk-Adjusted Metrics
| Metric | GH | MDLN |
|---|---|---|
| Sharpe Ratio (1Y) | 1.17 | -- |
| Sortino Ratio (1Y) | 1.84 | -- |
Profitability
ROE (TTM)
Capital efficiency shows on one side only: Medline (MDLN) earns 4.85% on shareholders’ equity, ranked against its industry; Guardant Health (GH) has no ROE this period.
GH
Health Care Equipment & Services industry group
--
- Max
- 47.61%
- Q3
- 14.36%
- Median
- 5.45%
- Q1
- -10.67%
- Min
- -47.01%
- GH
- --
MDLN
Health Care Equipment & Services industry group
4.85%
- Max
- 47.61%
- Q3
- 14.36%
- Median
- 5.45%
- MDLN
- 4.85%
- Q1
- -10.67%
- Min
- -47.01%
Net Margin (TTM)
Guardant Health (GH) reports a negative net margin of -37.93%, usually indicating a net loss over the period. Meanwhile Medline (MDLN) reports 1.85%, ranking against industry peers normally.
GH
Health Care Equipment & Services industry group
-37.93%
- Max
- 29.35%
- Q3
- 9.33%
- Median
- 2.18%
- Q1
- -6.29%
- Min
- -28.46%
- GH
- -37.93%
MDLN
Health Care Equipment & Services industry group
1.85%
- Max
- 29.35%
- Q3
- 9.33%
- Median
- 2.18%
- MDLN
- 1.85%
- Q1
- -6.29%
- Min
- -28.46%
Operating Margin (TTM)
Guardant Health (GH) reports a negative operating margin of -37.06%, usually indicating that operating costs exceeded revenue at the operating-income line. Meanwhile Medline (MDLN) reports 5.22%, ranking against industry peers normally.
GH
Health Care Equipment & Services industry group
-37.06%
- Max
- 35.43%
- Q3
- 14.14%
- Median
- 6.81%
- Q1
- -0.28%
- Min
- -16.29%
- GH
- -37.06%
MDLN
Health Care Equipment & Services industry group
5.22%
- Max
- 35.43%
- Q3
- 14.14%
- Median
- 6.81%
- MDLN
- 5.22%
- Q1
- -0.28%
- Min
- -16.29%
Profitability Metrics
| Metric | GH | MDLN |
|---|---|---|
| ROE (TTM) | -- | 4.85% |
| ROA (TTM) | -19.92% | 2.70% |
| Net Margin (TTM) | -37.93% | 1.85% |
| Operating Margin (TTM) | -37.06% | 5.22% |
| Gross Margin (TTM) | 65.19% | 24.42% |
Growth
Revenue Growth
Only one side can be read here: Guardant Health (GH) reports revenue growth of 32.88%, ranked against its industry; Medline (MDLN) has no revenue growth figure this period.
EPS Growth
Only one side can be read here: Medline (MDLN) reports EPS growth of 117.38%, ranked against its industry; Guardant Health (GH) has no EPS growth figure this period.
Growth Metrics
| Metric | GH | MDLN |
|---|---|---|
| Revenue Growth (YoY) | 32.88% | -- |
| Revenue Growth (3Y CAGR) | 29.75% | -- |
| EPS Growth (YoY) | -- | 117.38% |
| EPS Growth (3Y CAGR) | -- | -- |
Financial Strength
Current Ratio (MRQ)
Guardant Health (GH) at 3.60 keeps current ratio within its industry’s typical mid-range, while Medline (MDLN) at 4.04 sits above its industry’s typical mid-range — comfortable liquidity, though possibly with more idle current assets relative to peers.
GH
Health Care Equipment & Services industry group
3.60
- Max
- 7.59
- Q3
- 4.00
- GH
- 3.60
- Median
- 1.98
- Q1
- 1.37
- Min
- 0.30
MDLN
Health Care Equipment & Services industry group
4.04
- Max
- 7.59
- MDLN
- 4.04
- Q3
- 4.00
- Median
- 1.98
- Q1
- 1.37
- Min
- 0.30
Debt / Equity (MRQ)
Only one side’s leverage can be read here: Medline (MDLN) carries debt-to-equity ratio of 0.65 against its industry range, while Guardant Health (GH) reports no figure this period.
GH
Health Care Equipment & Services industry group
--
- Max
- 1.88
- Q3
- 0.91
- Median
- 0.58
- Q1
- 0.16
- Min
- 0.00
- GH
- --
MDLN
Health Care Equipment & Services industry group
0.65
- Max
- 1.88
- Q3
- 0.91
- MDLN
- 0.65
- Median
- 0.58
- Q1
- 0.16
- Min
- 0.00
Financial Strength Metrics
| Metric | GH | MDLN |
|---|---|---|
| Current Ratio (MRQ) | 3.60 | 4.04 |
| Debt / Equity (MRQ) | -- | 0.65 |
| Net Debt / EBITDA | -- | 3.35 |
Dividends
Dividend Yield (TTM)
Neither Guardant Health (GH) nor Medline (MDLN) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.
GH
Health Care Equipment & Services industry group
0.00%
- GH
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
MDLN
Health Care Equipment & Services industry group
0.00%
- MDLN
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Payout Ratio (TTM)
Neither Guardant Health (GH) nor Medline (MDLN) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.
GH
Health Care Equipment & Services industry group
0.00%
- GH
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
MDLN
Health Care Equipment & Services industry group
0.00%
- MDLN
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Metrics
| Metric | GH | MDLN |
|---|---|---|
| Dividend Yield (TTM) | 0.00% | 0.00% |
| Dividend Payout Ratio (TTM) | 0.00% | 0.00% |
Valuation
P/E Ratio (TTM)
An earnings multiple is available for just one side: Medline (MDLN) trades at 90.09 times trailing earnings, ranked against its peers, while Guardant Health (GH) has no P/E ratio this period.
GH
Health Care Equipment & Services industry group
--
- Max
- 80.41
- Q3
- 47.62
- Median
- 29.93
- Q1
- 21.19
- Min
- 4.21
- GH
- --
MDLN
Health Care Equipment & Services industry group
90.09
- MDLN
- 90.09
- Max
- 80.41
- Q3
- 47.62
- Median
- 29.93
- Q1
- 21.19
- Min
- 4.21
P/S Ratio (TTM)
Medline (MDLN) at 1.70 prices around its industry’s typical P/S ratio, while Guardant Health (GH) at 15.96 clears its benchmark range — GH looks notably rich on sales.
GH
Health Care Equipment & Services industry group
15.96
- GH
- 15.96
- Max
- 8.80
- Q3
- 4.32
- Median
- 2.13
- Q1
- 1.10
- Min
- 0.03
MDLN
Health Care Equipment & Services industry group
1.70
- Max
- 8.80
- Q3
- 4.32
- Median
- 2.13
- MDLN
- 1.70
- Q1
- 1.10
- Min
- 0.03
P/B Ratio (MRQ)
Guardant Health (GH) reports a negative P/B ratio of -73.67, meaning negative book equity — the multiple itself is not meaningful for valuation. Meanwhile Medline (MDLN) reports 2.95, ranking against industry peers normally.
GH
Health Care Equipment & Services industry group
-73.67
- Max
- 11.68
- Q3
- 6.12
- Median
- 3.00
- Q1
- 1.73
- Min
- -1.31
- GH
- -73.67
MDLN
Health Care Equipment & Services industry group
2.95
- Max
- 11.68
- Q3
- 6.12
- Median
- 3.00
- MDLN
- 2.95
- Q1
- 1.73
- Min
- -1.31
Valuation Metrics
| Metric | GH | MDLN |
|---|---|---|
| P/E Ratio (TTM) | -- | 90.09 |
| P/S Ratio (TTM) | 15.96 | 1.70 |
| P/B Ratio (MRQ) | -73.67 | 2.95 |
| Free Cash Flow Yield (TTM) | -0.30% | 2.67% |