DGX vs. PEN: Quest Diagnostics vs. Penumbra Stock Comparison

November 11, 2026

How do Quest Diagnostics (DGX) and Penumbra (PEN) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Quest Diagnostics (DGX) and Penumbra (PEN) both fall under the Health Care Equipment & Services industry group, but DGX is classified in Health Care Providers & Services while PEN is classified in Health Care Equipment & Supplies.

Company profile comparison for Quest Diagnostics (DGX) and Penumbra (PEN)
Profile Item	DGX	PEN
Name	Quest Diagnostics Incorporated	Penumbra Inc.
Country/Region	United States	United States
GICS Sector	Health Care	Health Care
GICS Industry Group	Health Care Equipment & Services	Health Care Equipment & Services
GICS Industry	Health Care Providers & Services	Health Care Equipment & Supplies
GICS Sub-Industry	Health Care Services	Health Care Equipment
Market Capitalization	28.21 billion USD	12.58 billion USD
Currency	USD	USD
Exchange	NYSE	NYSE
Listing Date	December 17, 1996	September 18, 2015
Security Type	Common Stock	Common Stock

Price Performance

Cumulative Growth

DGX

PEN

GSPC

Quest Diagnostics (DGX) vs. Penumbra (PEN), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Quest Diagnostics (DGX) and Penumbra (PEN). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Quest Diagnostics (DGX) and Penumbra (PEN). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Quest Diagnostics (DGX) and Penumbra (PEN)
Metric	DGX	PEN
Total Return (1Y)	45.88%	20.52%
Total Return (3Y, Annualized)	27.45%	20.38%
Total Return (5Y, Annualized)	14.84%	3.15%

Risk Profile

Drawdown History

DGX

PEN

GSPC

Quest Diagnostics (DGX) vs. Penumbra (PEN), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Quest Diagnostics (DGX) and Penumbra (PEN). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Quest Diagnostics (DGX) and Penumbra (PEN)
Metric	DGX	PEN
Volatility (1Y, Annualized)	24.06%	19.78%
Beta (5Y)	0.54	0.68
Max Drawdown (5Y)	-28.62%	-59.60%
Avg. Volume (3M)	1.00M	348.64K

Risk-Adjusted Performance

Risk-Return Positioning

DGX and PEN are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Quest Diagnostics (DGX) and Penumbra (PEN)
Metric	DGX	PEN
Sharpe Ratio (1Y)	1.73	0.82
Sortino Ratio (1Y)	3.16	1.56

Profitability

ROE (TTM)

Quest Diagnostics (DGX) at 15.32% sits in the top ROE quartile, while Penumbra (PEN) at 10.67% is closer to the peer norm — stronger capital efficiency for DGX.

DGX

Health Care Equipment & Services industry group

15.32%

Max: 47.61%
DGX: 15.32%
Q3: 14.36%
Median: 5.45%
Q1: -10.67%
Min: -47.01%

PEN

Health Care Equipment & Services industry group

10.67%

Max: 47.61%
Q3: 14.36%
PEN: 10.67%
Median: 5.45%
Q1: -10.67%
Min: -47.01%

Quest Diagnostics (DGX) vs. Penumbra (PEN): A comparison of their ROE against the Health Care Equipment & Services industry group benchmark.

Net Margin (TTM)

For every dollar of sales, both Quest Diagnostics (DGX) at 9.54% and Penumbra (PEN) at 10.06% retain more as net profit than most peers, landing in the top net margin quartile of their industries.

DGX

Health Care Equipment & Services industry group

9.54%

Max: 29.35%
DGX: 9.54%
Q3: 9.33%
Median: 2.18%
Q1: -6.29%
Min: -28.46%

PEN

Health Care Equipment & Services industry group

10.06%

Max: 29.35%
PEN: 10.06%
Q3: 9.33%
Median: 2.18%
Q1: -6.29%
Min: -28.46%

Quest Diagnostics (DGX) vs. Penumbra (PEN): A comparison of their net margin against the Health Care Equipment & Services industry group benchmark.

Operating Margin (TTM)

Quest Diagnostics (DGX) at 15.63% operates in the top operating margin quartile, ahead of Penumbra (PEN) at 12.37%, which runs around its industry’s norm.

DGX

Health Care Equipment & Services industry group

15.63%

Max: 35.43%
DGX: 15.63%
Q3: 14.14%
Median: 6.81%
Q1: -0.28%
Min: -16.29%

PEN

Health Care Equipment & Services industry group

12.37%

Max: 35.43%
Q3: 14.14%
PEN: 12.37%
Median: 6.81%
Q1: -0.28%
Min: -16.29%

Quest Diagnostics (DGX) vs. Penumbra (PEN): A comparison of their operating margin against the Health Care Equipment & Services industry group benchmark.

Profitability Metrics

Profitability metrics for Quest Diagnostics (DGX) and Penumbra (PEN)
Metric	DGX	PEN
ROE (TTM)	15.32%	10.67%
ROA (TTM)	6.61%	6.28%
Net Margin (TTM)	9.54%	10.06%
Operating Margin (TTM)	15.63%	12.37%
Gross Margin (TTM)	33.18%	67.99%

Growth

Revenue Growth

Both Quest Diagnostics (DGX) at 11.78% and Penumbra (PEN) at 17.50% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

Quest Diagnostics (DGX) vs. Penumbra (PEN): A comparison of their Revenue Growth across different time periods.

EPS Growth

Penumbra (PEN) at 1,155.56% clears its industry range for EPS growth, a much stronger earnings trajectory than Quest Diagnostics (DGX) at 13.78%, which is closer to a typical peer reading.

Quest Diagnostics (DGX) vs. Penumbra (PEN): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Quest Diagnostics (DGX) and Penumbra (PEN)
Metric	DGX	PEN
Revenue Growth (YoY)	11.78%	17.50%
Revenue Growth (3Y CAGR)	3.74%	18.33%
EPS Growth (YoY)	13.78%	1,155.56%
EPS Growth (3Y CAGR)	3.16%	--

Financial Strength

Current Ratio (MRQ)

Quest Diagnostics (DGX) at 1.70 keeps current ratio within its industry’s typical mid-range, while Penumbra (PEN) at 5.89 sits above its industry’s typical mid-range — comfortable liquidity, though possibly with more idle current assets relative to peers.

DGX

Health Care Equipment & Services industry group

1.70

Max: 7.59
Q3: 4.00
Median: 1.98
DGX: 1.70
Q1: 1.37
Min: 0.30

PEN

Health Care Equipment & Services industry group

5.89

Max: 7.59
PEN: 5.89
Q3: 4.00
Median: 1.98
Q1: 1.37
Min: 0.30

Quest Diagnostics (DGX) vs. Penumbra (PEN): A comparison of their current ratio against the Health Care Equipment & Services industry group benchmark.

Debt / Equity (MRQ)

Penumbra (PEN) at 0.13 keeps leverage in the lower industry quartile, while Quest Diagnostics (DGX) at 0.80 runs a more typical debt-to-equity mix.

DGX

Health Care Equipment & Services industry group

0.80

Max: 1.88
Q3: 0.91
DGX: 0.80
Median: 0.58
Q1: 0.16
Min: 0.00

PEN

Health Care Equipment & Services industry group

0.13

Max: 1.88
Q3: 0.91
Median: 0.58
Q1: 0.16
PEN: 0.13
Min: 0.00

Quest Diagnostics (DGX) vs. Penumbra (PEN): A comparison of their debt-to-equity ratio against the Health Care Equipment & Services industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Quest Diagnostics (DGX) and Penumbra (PEN)
Metric	DGX	PEN
Current Ratio (MRQ)	1.70	5.89
Debt / Equity (MRQ)	0.80	0.13
Net Debt / EBITDA	2.38	-2.22

Dividends

Dividend Yield (TTM)

Penumbra (PEN) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Quest Diagnostics (DGX) reports a yield of 1.33%, ranking against industry peers normally.

DGX

Health Care Equipment & Services industry group

1.33%

DGX: 1.33%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

PEN

Health Care Equipment & Services industry group

0.00%

PEN: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Quest Diagnostics (DGX) vs. Penumbra (PEN): A comparison of their dividend yield against the Health Care Equipment & Services industry group benchmark.

Dividend Payout Ratio (TTM)

Penumbra (PEN) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Quest Diagnostics (DGX) reports a payout of 25.10%, ranking against industry peers normally.

DGX

Health Care Equipment & Services industry group

25.10%

DGX: 25.10%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

PEN

Health Care Equipment & Services industry group

0.00%

PEN: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Quest Diagnostics (DGX) vs. Penumbra (PEN): A comparison of their payout ratio against the Health Care Equipment & Services industry group benchmark.

Dividend Metrics

Dividend metrics for Quest Diagnostics (DGX) and Penumbra (PEN)
Metric	DGX	PEN
Dividend Yield (TTM)	1.33%	0.00%
Dividend Payout Ratio (TTM)	25.10%	0.00%

Valuation

P/E Ratio (TTM)

Quest Diagnostics (DGX) at 25.46 is near its industry’s usual P/E ratio, while Penumbra (PEN) at 80.41 sits in the richer quartile — PEN needs stronger growth or earnings quality to justify the premium.

DGX

Health Care Equipment & Services industry group

25.46

Max: 80.41
Q3: 47.62
Median: 29.93
DGX: 25.46
Q1: 21.19
Min: 4.21

PEN

Health Care Equipment & Services industry group

80.41

PEN: 80.41
Max: 80.41
Q3: 47.62
Median: 29.93
Q1: 21.19
Min: 4.21

Quest Diagnostics (DGX) vs. Penumbra (PEN): A comparison of their P/E ratio against the Health Care Equipment & Services industry group benchmark.

P/S Ratio (TTM)

Quest Diagnostics (DGX) at 2.38 is priced about in line with its industry on P/S ratio, while Penumbra (PEN) at 8.06 sits in the pricier quartile — PEN costs more per dollar of sales.

DGX

Health Care Equipment & Services industry group

2.38

Max: 8.80
Q3: 4.32
DGX: 2.38
Median: 2.13
Q1: 1.10
Min: 0.03

PEN

Health Care Equipment & Services industry group

8.06

Max: 8.80
PEN: 8.06
Q3: 4.32
Median: 2.13
Q1: 1.10
Min: 0.03

Quest Diagnostics (DGX) vs. Penumbra (PEN): A comparison of their P/S ratio against the Health Care Equipment & Services industry group benchmark.

P/B Ratio (MRQ)

Quest Diagnostics (DGX) at 3.68 is valued about in line with its industry on P/B ratio, while Penumbra (PEN) at 7.95 carries an above-peer premium to book — PEN is pricier on assets.

DGX

Health Care Equipment & Services industry group

3.68

Max: 11.68
Q3: 6.12
DGX: 3.68
Median: 3.00
Q1: 1.73
Min: -1.31

PEN

Health Care Equipment & Services industry group

7.95

Max: 11.68
PEN: 7.95
Q3: 6.12
Median: 3.00
Q1: 1.73
Min: -1.31

Quest Diagnostics (DGX) vs. Penumbra (PEN): A comparison of their P/B ratio against the Health Care Equipment & Services industry group benchmark.

Valuation Metrics

Valuation metrics for Quest Diagnostics (DGX) and Penumbra (PEN)
Metric	DGX	PEN
P/E Ratio (TTM)	25.46	80.41
P/S Ratio (TTM)	2.38	8.06
P/B Ratio (MRQ)	3.68	7.95
Free Cash Flow Yield (TTM)	3.09%	1.32%