DGX vs. GH: Quest Diagnostics vs. Guardant Health Stock Comparison
How do Quest Diagnostics (DGX) and Guardant Health (GH) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.
Company Profile
Quest Diagnostics (DGX) and Guardant Health (GH) are both classified in the Health Care Services sub-industry within the broader Health Care Providers & Services industry, placing them in the closest GICS peer bucket.
| Profile Item | DGX | GH |
|---|---|---|
| Name | Quest Diagnostics Incorporated | Guardant Health, Inc. |
| Country/Region | United States | United States |
| GICS Sector | Health Care | Health Care |
| GICS Industry Group | Health Care Equipment & Services | Health Care Equipment & Services |
| GICS Industry | Health Care Providers & Services | Health Care Providers & Services |
| GICS Sub-Industry | Health Care Services | Health Care Services |
| Market Capitalization | 28.21 billion USD | 20.41 billion USD |
| Currency | USD | USD |
| Exchange | NYSE | Nasdaq |
| Listing Date | December 17, 1996 | October 4, 2018 |
| Security Type | Common Stock | Common Stock |
Price Performance
Cumulative Growth
Trailing Returns
Calendar-Year Returns
Performance Metrics
| Metric | DGX | GH |
|---|---|---|
| Total Return (1Y) | 45.88% | 66.53% |
| Total Return (3Y, Annualized) | 27.45% | 92.76% |
| Total Return (5Y, Annualized) | 14.84% | 8.36% |
Risk Profile
Drawdown History
Return Distribution
Risk Metrics
Guardant Health (GH) has an aggressive beta of 1.69, indicating higher sensitivity to broad-market moves, while Quest Diagnostics (DGX) is defensive at 0.54 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.
| Metric | DGX | GH |
|---|---|---|
| Volatility (1Y, Annualized) | 24.06% | 53.23% |
| Beta (5Y) | 0.54 | 1.69 |
| Max Drawdown (5Y) | -28.62% | -85.09% |
| Avg. Volume (3M) | 1.00M | 1.97M |
Risk-Adjusted Performance
Risk-Return Positioning
Risk-Adjusted Metrics
| Metric | DGX | GH |
|---|---|---|
| Sharpe Ratio (1Y) | 1.73 | 1.17 |
| Sortino Ratio (1Y) | 3.16 | 1.84 |
Profitability
ROE (TTM)
Capital efficiency shows on one side only: Quest Diagnostics (DGX) earns 15.32% on shareholders’ equity, ranked against its industry; Guardant Health (GH) has no ROE this period.
DGX
Health Care Equipment & Services industry group
15.32%
- Max
- 47.61%
- DGX
- 15.32%
- Q3
- 14.36%
- Median
- 5.45%
- Q1
- -10.67%
- Min
- -47.01%
GH
Health Care Equipment & Services industry group
--
- Max
- 47.61%
- Q3
- 14.36%
- Median
- 5.45%
- Q1
- -10.67%
- Min
- -47.01%
- GH
- --
Net Margin (TTM)
Guardant Health (GH) reports a negative net margin of -37.93%, usually indicating a net loss over the period. Meanwhile Quest Diagnostics (DGX) reports 9.54%, ranking against industry peers normally.
DGX
Health Care Equipment & Services industry group
9.54%
- Max
- 29.35%
- DGX
- 9.54%
- Q3
- 9.33%
- Median
- 2.18%
- Q1
- -6.29%
- Min
- -28.46%
GH
Health Care Equipment & Services industry group
-37.93%
- Max
- 29.35%
- Q3
- 9.33%
- Median
- 2.18%
- Q1
- -6.29%
- Min
- -28.46%
- GH
- -37.93%
Operating Margin (TTM)
Guardant Health (GH) reports a negative operating margin of -37.06%, usually indicating that operating costs exceeded revenue at the operating-income line. Meanwhile Quest Diagnostics (DGX) reports 15.63%, ranking against industry peers normally.
DGX
Health Care Equipment & Services industry group
15.63%
- Max
- 35.43%
- DGX
- 15.63%
- Q3
- 14.14%
- Median
- 6.81%
- Q1
- -0.28%
- Min
- -16.29%
GH
Health Care Equipment & Services industry group
-37.06%
- Max
- 35.43%
- Q3
- 14.14%
- Median
- 6.81%
- Q1
- -0.28%
- Min
- -16.29%
- GH
- -37.06%
Profitability Metrics
| Metric | DGX | GH |
|---|---|---|
| ROE (TTM) | 15.32% | -- |
| ROA (TTM) | 6.61% | -19.92% |
| Net Margin (TTM) | 9.54% | -37.93% |
| Operating Margin (TTM) | 15.63% | -37.06% |
| Gross Margin (TTM) | 33.18% | 65.19% |
Growth
Revenue Growth
Guardant Health (GH) at 32.88% sits in the top revenue growth quartile, while Quest Diagnostics (DGX) at 11.78% is closer to the peer norm — faster top-line expansion for GH.
EPS Growth
Only one side can be read here: Quest Diagnostics (DGX) reports EPS growth of 13.78%, ranked against its industry; Guardant Health (GH) has no EPS growth figure this period.
Growth Metrics
| Metric | DGX | GH |
|---|---|---|
| Revenue Growth (YoY) | 11.78% | 32.88% |
| Revenue Growth (3Y CAGR) | 3.74% | 29.75% |
| EPS Growth (YoY) | 13.78% | -- |
| EPS Growth (3Y CAGR) | 3.16% | -- |
Financial Strength
Current Ratio (MRQ)
Both Quest Diagnostics (DGX) at 1.70 and Guardant Health (GH) at 3.60 carry current ratio within their industries’ typical mid-ranges, suggesting balanced short-term liquidity relative to peers.
DGX
Health Care Equipment & Services industry group
1.70
- Max
- 7.59
- Q3
- 4.00
- Median
- 1.98
- DGX
- 1.70
- Q1
- 1.37
- Min
- 0.30
GH
Health Care Equipment & Services industry group
3.60
- Max
- 7.59
- Q3
- 4.00
- GH
- 3.60
- Median
- 1.98
- Q1
- 1.37
- Min
- 0.30
Debt / Equity (MRQ)
Only one side’s leverage can be read here: Quest Diagnostics (DGX) carries debt-to-equity ratio of 0.80 against its industry range, while Guardant Health (GH) reports no figure this period.
DGX
Health Care Equipment & Services industry group
0.80
- Max
- 1.88
- Q3
- 0.91
- DGX
- 0.80
- Median
- 0.58
- Q1
- 0.16
- Min
- 0.00
GH
Health Care Equipment & Services industry group
--
- Max
- 1.88
- Q3
- 0.91
- Median
- 0.58
- Q1
- 0.16
- Min
- 0.00
- GH
- --
Financial Strength Metrics
| Metric | DGX | GH |
|---|---|---|
| Current Ratio (MRQ) | 1.70 | 3.60 |
| Debt / Equity (MRQ) | 0.80 | -- |
| Net Debt / EBITDA | 2.38 | -- |
Dividends
Dividend Yield (TTM)
Guardant Health (GH) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Quest Diagnostics (DGX) reports a yield of 1.33%, ranking against industry peers normally.
DGX
Health Care Equipment & Services industry group
1.33%
- DGX
- 1.33%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
GH
Health Care Equipment & Services industry group
0.00%
- GH
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Payout Ratio (TTM)
Guardant Health (GH) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Quest Diagnostics (DGX) reports a payout of 25.10%, ranking against industry peers normally.
DGX
Health Care Equipment & Services industry group
25.10%
- DGX
- 25.10%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
GH
Health Care Equipment & Services industry group
0.00%
- GH
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Metrics
| Metric | DGX | GH |
|---|---|---|
| Dividend Yield (TTM) | 1.33% | 0.00% |
| Dividend Payout Ratio (TTM) | 25.10% | 0.00% |
Valuation
P/E Ratio (TTM)
An earnings multiple is available for just one side: Quest Diagnostics (DGX) trades at 25.46 times trailing earnings, ranked against its peers, while Guardant Health (GH) has no P/E ratio this period.
DGX
Health Care Equipment & Services industry group
25.46
- Max
- 80.41
- Q3
- 47.62
- Median
- 29.93
- DGX
- 25.46
- Q1
- 21.19
- Min
- 4.21
GH
Health Care Equipment & Services industry group
--
- Max
- 80.41
- Q3
- 47.62
- Median
- 29.93
- Q1
- 21.19
- Min
- 4.21
- GH
- --
P/S Ratio (TTM)
Quest Diagnostics (DGX) at 2.38 prices around its industry’s typical P/S ratio, while Guardant Health (GH) at 15.96 clears its benchmark range — GH looks notably rich on sales.
DGX
Health Care Equipment & Services industry group
2.38
- Max
- 8.80
- Q3
- 4.32
- DGX
- 2.38
- Median
- 2.13
- Q1
- 1.10
- Min
- 0.03
GH
Health Care Equipment & Services industry group
15.96
- GH
- 15.96
- Max
- 8.80
- Q3
- 4.32
- Median
- 2.13
- Q1
- 1.10
- Min
- 0.03
P/B Ratio (MRQ)
Guardant Health (GH) reports a negative P/B ratio of -73.67, meaning negative book equity — the multiple itself is not meaningful for valuation. Meanwhile Quest Diagnostics (DGX) reports 3.68, ranking against industry peers normally.
DGX
Health Care Equipment & Services industry group
3.68
- Max
- 11.68
- Q3
- 6.12
- DGX
- 3.68
- Median
- 3.00
- Q1
- 1.73
- Min
- -1.31
GH
Health Care Equipment & Services industry group
-73.67
- Max
- 11.68
- Q3
- 6.12
- Median
- 3.00
- Q1
- 1.73
- Min
- -1.31
- GH
- -73.67
Valuation Metrics
| Metric | DGX | GH |
|---|---|---|
| P/E Ratio (TTM) | 25.46 | -- |
| P/S Ratio (TTM) | 2.38 | 15.96 |
| P/B Ratio (MRQ) | 3.68 | -73.67 |
| Free Cash Flow Yield (TTM) | 3.09% | -0.30% |