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CRL vs. ZTS: Charles River Laboratories vs. Zoetis Stock Comparison

How do Charles River Laboratories (CRL) and Zoetis (ZTS) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Charles River Laboratories (CRL) and Zoetis (ZTS) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but CRL is classified in Life Sciences Tools & Services while ZTS is classified in Pharmaceuticals.

Company profile comparison for Charles River Laboratories (CRL) and Zoetis (ZTS)
Profile ItemCRLZTS
NameCharles River Laboratories International, Inc.Zoetis Inc. Class A Common Stock
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryLife Sciences Tools & ServicesPharmaceuticals
GICS Sub-IndustryLife Sciences Tools & ServicesPharmaceuticals
Market Capitalization16.17 billion USD32.26 billion USD
CurrencyUSDUSD
ExchangeNYSENYSE
Listing DateJune 23, 2000February 1, 2013
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

CRL
ZTS
GSPC
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Charles River Laboratories (CRL) vs. Zoetis (ZTS), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Charles River Laboratories (CRL) and Zoetis (ZTS). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Charles River Laboratories (CRL) and Zoetis (ZTS). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Charles River Laboratories (CRL) and Zoetis (ZTS)
MetricCRLZTS
Total Return (1Y)110.83%-30.10%
Total Return (3Y, Annualized)27.87%-20.42%
Total Return (5Y, Annualized)-1.57%-16.87%

Risk Profile

Drawdown History

CRL
ZTS
GSPC
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Charles River Laboratories (CRL) vs. Zoetis (ZTS), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Charles River Laboratories (CRL) and Zoetis (ZTS). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Charles River Laboratories (CRL) has an aggressive beta of 1.33, indicating higher sensitivity to broad-market moves, while Zoetis (ZTS) is defensive at 0.66 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.

Risk profile metrics for Charles River Laboratories (CRL) and Zoetis (ZTS)
MetricCRLZTS
Volatility (1Y, Annualized)47.81%38.23%
Beta (5Y)1.330.66
Max Drawdown (5Y)-74.73%-70.45%
Avg. Volume (3M)1.05M4.65M

Risk-Adjusted Performance

Risk-Return Positioning

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CRL and ZTS are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Charles River Laboratories (CRL) and Zoetis (ZTS)
MetricCRLZTS
Sharpe Ratio (1Y)2.23-0.90
Sortino Ratio (1Y)3.58-1.10

Profitability

ROE (TTM)

Zoetis (ZTS) at 57.63% sits in the top ROE quartile, while Charles River Laboratories (CRL) at 1.27% is closer to the peer norm — stronger capital efficiency for ZTS.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.27%

Max
109.18%
Q3
6.23%
CRL
1.27%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

ZTS

Pharmaceuticals, Biotechnology & Life Sciences industry group

57.63%

Max
109.18%
ZTS
57.63%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Charles River Laboratories (CRL) vs. Zoetis (ZTS): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Zoetis (ZTS) at 26.41% converts revenue to bottom-line profit above its industry’s benchmark range, while Charles River Laboratories (CRL) at 1.01% keeps roughly the typical share for its industry.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.01%

Max
18.05%
Q3
4.78%
CRL
1.01%
Median
0.00%
Q1
-4.14%
Min
-17.05%

ZTS

Pharmaceuticals, Biotechnology & Life Sciences industry group

26.41%

ZTS
26.41%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Charles River Laboratories (CRL) vs. Zoetis (ZTS): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Charles River Laboratories (CRL) at 23.42% and Zoetis (ZTS) at 38.19% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

23.42%

Max
83.12%
CRL
23.42%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

ZTS

Pharmaceuticals, Biotechnology & Life Sciences industry group

38.19%

Max
83.12%
ZTS
38.19%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Charles River Laboratories (CRL) vs. Zoetis (ZTS): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Charles River Laboratories (CRL) and Zoetis (ZTS)
MetricCRLZTS
ROE (TTM)1.27%57.63%
ROA (TTM)4.74%14.87%
Net Margin (TTM)1.01%26.41%
Operating Margin (TTM)23.42%38.19%
Gross Margin (TTM)35.10%71.65%

Growth

Revenue Growth

Zoetis (ZTS) at 2.28% is around its peer norm for revenue growth, while Charles River Laboratories (CRL) at -0.85% drops into the bottom quartile, signaling weaker demand or pricing momentum.

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Charles River Laboratories (CRL) vs. Zoetis (ZTS): A comparison of their Revenue Growth across different time periods.

EPS Growth

Zoetis (ZTS) at 10.05% is around its peer norm for EPS growth, while Charles River Laboratories (CRL) at -1,555.00% falls below its industry range, a notably weak earnings reading.

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Charles River Laboratories (CRL) vs. Zoetis (ZTS): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Charles River Laboratories (CRL) and Zoetis (ZTS)
MetricCRLZTS
Revenue Growth (YoY)-0.85%2.28%
Revenue Growth (3Y CAGR)0.33%5.42%
EPS Growth (YoY)-1,555.00%10.05%
EPS Growth (3Y CAGR)--10.27%

Financial Strength

Current Ratio (MRQ)

Both Charles River Laboratories (CRL) at 1.41 and Zoetis (ZTS) at 2.35 run current ratio in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.41

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
CRL
1.41
Min
0.10

ZTS

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.35

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
ZTS
2.35
Min
0.10
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Charles River Laboratories (CRL) vs. Zoetis (ZTS): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Both balance sheets lean debt-heavy versus peers, but ZTS is more stretched: Charles River Laboratories (CRL) at 0.87 sits in the higher-leverage quartile and Zoetis (ZTS) at 2.80 is above its industry benchmark range.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.87

Max
1.42
CRL
0.87
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

ZTS

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.80

ZTS
2.80
Max
1.42
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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Charles River Laboratories (CRL) vs. Zoetis (ZTS): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Charles River Laboratories (CRL) and Zoetis (ZTS)
MetricCRLZTS
Current Ratio (MRQ)1.412.35
Debt / Equity (MRQ)0.872.80
Net Debt / EBITDA2.921.92

Dividends

Dividend Yield (TTM)

Charles River Laboratories (CRL) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Zoetis (ZTS) reports a yield of 2.55%, ranking against industry peers normally.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

CRL
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

ZTS

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.55%

ZTS
2.55%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Charles River Laboratories (CRL) vs. Zoetis (ZTS): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Charles River Laboratories (CRL) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Zoetis (ZTS) reports a payout of 35.24%, ranking against industry peers normally.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

CRL
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

ZTS

Pharmaceuticals, Biotechnology & Life Sciences industry group

35.24%

ZTS
35.24%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Charles River Laboratories (CRL) vs. Zoetis (ZTS): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Charles River Laboratories (CRL) and Zoetis (ZTS)
MetricCRLZTS
Dividend Yield (TTM)0.00%2.55%
Dividend Payout Ratio (TTM)0.00%35.24%

Valuation

P/E Ratio (TTM)

Zoetis (ZTS) at 13.50 is near its industry’s usual P/E ratio, while Charles River Laboratories (CRL) at 366.87 sits above its peer range — an unusually expensive price for CRL’s trailing earnings.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

366.87

CRL
366.87
Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07

ZTS

Pharmaceuticals, Biotechnology & Life Sciences industry group

13.50

Max
85.34
Q3
43.46
Median
26.69
ZTS
13.50
Q1
13.30
Min
0.07
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Charles River Laboratories (CRL) vs. Zoetis (ZTS): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

On P/S ratio, both Charles River Laboratories (CRL) at 4.07 and Zoetis (ZTS) at 3.40 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.07

Max
58.18
Q3
25.77
Median
7.30
CRL
4.07
Q1
3.01
Min
0.01

ZTS

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.40

Max
58.18
Q3
25.77
Median
7.30
ZTS
3.40
Q1
3.01
Min
0.01
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Charles River Laboratories (CRL) vs. Zoetis (ZTS): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Charles River Laboratories (CRL) at 5.01 is valued about in line with its industry on P/B ratio, while Zoetis (ZTS) at 9.80 carries an above-peer premium to book — ZTS is pricier on assets.

CRL

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.01

Max
13.53
Q3
6.54
CRL
5.01
Median
3.25
Q1
1.69
Min
-5.59

ZTS

Pharmaceuticals, Biotechnology & Life Sciences industry group

9.80

Max
13.53
ZTS
9.80
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
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Charles River Laboratories (CRL) vs. Zoetis (ZTS): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Charles River Laboratories (CRL) and Zoetis (ZTS)
MetricCRLZTS
P/E Ratio (TTM)366.8713.50
P/S Ratio (TTM)4.073.40
P/B Ratio (MRQ)5.019.80
Free Cash Flow Yield (TTM)2.74%6.36%