COR vs. ISRG: Cencora vs. Intuitive Surgical Stock Comparison

November 11, 2026

How do Cencora (COR) and Intuitive Surgical (ISRG) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Cencora (COR) and Intuitive Surgical (ISRG) both fall under the Health Care Equipment & Services industry group, but COR is classified in Health Care Providers & Services while ISRG is classified in Health Care Equipment & Supplies.

Company profile comparison for Cencora (COR) and Intuitive Surgical (ISRG)
Profile Item	COR	ISRG
Name	Cencora Inc.	Intuitive Surgical Inc.
Country/Region	United States	United States
GICS Sector	Health Care	Health Care
GICS Industry Group	Health Care Equipment & Services	Health Care Equipment & Services
GICS Industry	Health Care Providers & Services	Health Care Equipment & Supplies
GICS Sub-Industry	Health Care Distributors	Health Care Equipment
Market Capitalization	63.65 billion USD	159.96 billion USD
Currency	USD	USD
Exchange	NYSE	Nasdaq
Listing Date	April 4, 1995	June 16, 2000
Security Type	Common Stock	Common Stock

Price Performance

Cumulative Growth

COR

ISRG

GSPC

Cencora (COR) vs. Intuitive Surgical (ISRG), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

Loading price history…

Trailing total returns for Cencora (COR) and Intuitive Surgical (ISRG). Returns over one year are annualized.

Calendar-Year Returns

Loading price history…

Calendar-year total returns for Cencora (COR) and Intuitive Surgical (ISRG). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Cencora (COR) and Intuitive Surgical (ISRG)
Metric	COR	ISRG
Total Return (1Y)	-3.53%	-17.61%
Total Return (3Y, Annualized)	21.62%	19.20%
Total Return (5Y, Annualized)	24.10%	4.85%

Risk Profile

Drawdown History

COR

ISRG

GSPC

Cencora (COR) vs. Intuitive Surgical (ISRG), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

Loading price history…

Distribution of monthly total returns for Cencora (COR) and Intuitive Surgical (ISRG). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Intuitive Surgical (ISRG) has an aggressive beta of 1.41, indicating higher sensitivity to broad-market moves, while Cencora (COR) is defensive at 0.56 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.

Risk profile metrics for Cencora (COR) and Intuitive Surgical (ISRG)
Metric	COR	ISRG
Volatility (1Y, Annualized)	31.90%	35.53%
Beta (5Y)	0.56	1.41
Max Drawdown (5Y)	-32.44%	-49.88%
Avg. Volume (3M)	1.29M	2.43M

Risk-Adjusted Performance

Risk-Return Positioning

COR and ISRG are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Cencora (COR) and Intuitive Surgical (ISRG)
Metric	COR	ISRG
Sharpe Ratio (1Y)	-0.24	-0.62
Sortino Ratio (1Y)	-0.30	-0.83

Profitability

ROE (TTM)

Both companies show strong equity returns, but Cencora (COR) at 129.01% is the standout with ROE above its industry range; Intuitive Surgical (ISRG) at 17.93% also sits in the top quartile.

COR

Health Care Equipment & Services industry group

129.01%

COR: 129.01%
Max: 47.61%
Q3: 14.36%
Median: 5.45%
Q1: -10.67%
Min: -47.01%

ISRG

Health Care Equipment & Services industry group

17.93%

Max: 47.61%
ISRG: 17.93%
Q3: 14.36%
Median: 5.45%
Q1: -10.67%
Min: -47.01%

Cencora (COR) vs. Intuitive Surgical (ISRG): A comparison of their ROE against the Health Care Equipment & Services industry group benchmark.

Net Margin (TTM)

Intuitive Surgical (ISRG) at 25.54% retains a top-quartile share of revenue as profit, ahead of Cencora (COR) at 1.03%, which keeps about the industry-typical share.

COR

Health Care Equipment & Services industry group

1.03%

Max: 29.35%
Q3: 9.33%
Median: 2.18%
COR: 1.03%
Q1: -6.29%
Min: -28.46%

ISRG

Health Care Equipment & Services industry group

25.54%

Max: 29.35%
ISRG: 25.54%
Q3: 9.33%
Median: 2.18%
Q1: -6.29%
Min: -28.46%

Cencora (COR) vs. Intuitive Surgical (ISRG): A comparison of their net margin against the Health Care Equipment & Services industry group benchmark.

Operating Margin (TTM)

Intuitive Surgical (ISRG) at 33.29% operates in the top operating margin quartile, ahead of Cencora (COR) at 1.27%, which runs around its industry’s norm.

COR

Health Care Equipment & Services industry group

1.27%

Max: 35.43%
Q3: 14.14%
Median: 6.81%
COR: 1.27%
Q1: -0.28%
Min: -16.29%

ISRG

Health Care Equipment & Services industry group

33.29%

Max: 35.43%
ISRG: 33.29%
Q3: 14.14%
Median: 6.81%
Q1: -0.28%
Min: -16.29%

Cencora (COR) vs. Intuitive Surgical (ISRG): A comparison of their operating margin against the Health Care Equipment & Services industry group benchmark.

Profitability Metrics

Profitability metrics for Cencora (COR) and Intuitive Surgical (ISRG)
Metric	COR	ISRG
ROE (TTM)	129.01%	17.93%
ROA (TTM)	3.57%	11.86%
Net Margin (TTM)	1.03%	25.54%
Operating Margin (TTM)	1.27%	33.29%
Gross Margin (TTM)	4.09%	66.64%

Growth

Revenue Growth

Only one side can be read here: Intuitive Surgical (ISRG) reports revenue growth of 20.51%, ranked against its industry; Cencora (COR) has no revenue growth figure this period.

Cencora (COR) vs. Intuitive Surgical (ISRG): A comparison of their Revenue Growth across different time periods.

EPS Growth

Cencora (COR) at 125.50% clears its industry range for EPS growth, a much stronger earnings trajectory than Intuitive Surgical (ISRG) at 22.59%, which is closer to a typical peer reading.

Cencora (COR) vs. Intuitive Surgical (ISRG): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Cencora (COR) and Intuitive Surgical (ISRG)
Metric	COR	ISRG
Revenue Growth (YoY)	--	20.51%
Revenue Growth (3Y CAGR)	--	17.39%
EPS Growth (YoY)	125.50%	22.59%
EPS Growth (3Y CAGR)	28.15%	29.19%

Financial Strength

Current Ratio (MRQ)

Intuitive Surgical (ISRG) at 3.33 keeps current ratio within its industry’s typical mid-range, while Cencora (COR) at 0.94 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for COR.

COR

Health Care Equipment & Services industry group

0.94

Max: 7.59
Q3: 4.00
Median: 1.98
Q1: 1.37
COR: 0.94
Min: 0.30

ISRG

Health Care Equipment & Services industry group

3.33

Max: 7.59
Q3: 4.00
ISRG: 3.33
Median: 1.98
Q1: 1.37
Min: 0.30

Cencora (COR) vs. Intuitive Surgical (ISRG): A comparison of their current ratio against the Health Care Equipment & Services industry group benchmark.

Debt / Equity (MRQ)

Only one side’s leverage can be read here: Cencora (COR) carries debt-to-equity ratio of 3.06 against its industry range, while Intuitive Surgical (ISRG) reports no figure this period.

COR

Health Care Equipment & Services industry group

3.06

COR: 3.06
Max: 1.88
Q3: 0.91
Median: 0.58
Q1: 0.16
Min: 0.00

ISRG

Health Care Equipment & Services industry group

Max: 1.88
Q3: 0.91
Median: 0.58
Q1: 0.16
Min: 0.00
ISRG: --

Cencora (COR) vs. Intuitive Surgical (ISRG): ISRG does not report debt-to-equity ratio, so it has no value marker; COR is benchmarked against the Health Care Equipment & Services industry group.

Financial Strength Metrics

Financial strength metrics for Cencora (COR) and Intuitive Surgical (ISRG)
Metric	COR	ISRG
Current Ratio (MRQ)	0.94	3.33
Debt / Equity (MRQ)	3.06	--
Net Debt / EBITDA	1.12	-0.90

Dividends

Dividend Yield (TTM)

Intuitive Surgical (ISRG) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Cencora (COR) reports a yield of 0.71%, ranking against industry peers normally.

COR

Health Care Equipment & Services industry group

0.71%

COR: 0.71%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

ISRG

Health Care Equipment & Services industry group

0.00%

ISRG: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Cencora (COR) vs. Intuitive Surgical (ISRG): A comparison of their dividend yield against the Health Care Equipment & Services industry group benchmark.

Dividend Payout Ratio (TTM)

Intuitive Surgical (ISRG) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Cencora (COR) reports a payout of 17.45%, ranking against industry peers normally.

COR

Health Care Equipment & Services industry group

17.45%

COR: 17.45%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

ISRG

Health Care Equipment & Services industry group

0.00%

ISRG: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Cencora (COR) vs. Intuitive Surgical (ISRG): A comparison of their payout ratio against the Health Care Equipment & Services industry group benchmark.

Dividend Metrics

Dividend metrics for Cencora (COR) and Intuitive Surgical (ISRG)
Metric	COR	ISRG
Dividend Yield (TTM)	0.71%	0.00%
Dividend Payout Ratio (TTM)	17.45%	0.00%

Valuation

P/E Ratio (TTM)

Cencora (COR) at 18.58 sits in the cheaper P/E ratio quartile, while Intuitive Surgical (ISRG) at 54.75 sits in the richer quartile — a clear split in what investors pay for each dollar of trailing earnings.

COR

Health Care Equipment & Services industry group

18.58

Max: 80.41
Q3: 47.62
Median: 29.93
Q1: 21.19
COR: 18.58
Min: 4.21

ISRG

Health Care Equipment & Services industry group

54.75

Max: 80.41
ISRG: 54.75
Q3: 47.62
Median: 29.93
Q1: 21.19
Min: 4.21

Cencora (COR) vs. Intuitive Surgical (ISRG): A comparison of their P/E ratio against the Health Care Equipment & Services industry group benchmark.

P/S Ratio (TTM)

Cencora (COR) at 0.19 sits in the cheaper P/S ratio quartile while Intuitive Surgical (ISRG) at 13.82 prices above its industry range — a wide gap in sales valuation between them.

COR

Health Care Equipment & Services industry group

0.19

Max: 8.80
Q3: 4.32
Median: 2.13
Q1: 1.10
COR: 0.19
Min: 0.03

ISRG

Health Care Equipment & Services industry group

13.82

ISRG: 13.82
Max: 8.80
Q3: 4.32
Median: 2.13
Q1: 1.10
Min: 0.03

Cencora (COR) vs. Intuitive Surgical (ISRG): A comparison of their P/S ratio against the Health Care Equipment & Services industry group benchmark.

P/B Ratio (MRQ)

Both look rich against book: Intuitive Surgical (ISRG) at 9.82 sits in the upper P/B ratio quartile, and Cencora (COR) at 17.29 prices even higher, above its industry range.

COR

Health Care Equipment & Services industry group

17.29

COR: 17.29
Max: 11.68
Q3: 6.12
Median: 3.00
Q1: 1.73
Min: -1.31

ISRG

Health Care Equipment & Services industry group

9.82

Max: 11.68
ISRG: 9.82
Q3: 6.12
Median: 3.00
Q1: 1.73
Min: -1.31

Cencora (COR) vs. Intuitive Surgical (ISRG): A comparison of their P/B ratio against the Health Care Equipment & Services industry group benchmark.

Valuation Metrics

Valuation metrics for Cencora (COR) and Intuitive Surgical (ISRG)
Metric	COR	ISRG
P/E Ratio (TTM)	18.58	54.75
P/S Ratio (TTM)	0.19	13.82
P/B Ratio (MRQ)	17.29	9.82
Free Cash Flow Yield (TTM)	2.81%	2.15%