CAH vs. PEN: Cardinal Health vs. Penumbra Stock Comparison

November 11, 2026

How do Cardinal Health (CAH) and Penumbra (PEN) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Cardinal Health (CAH) and Penumbra (PEN) both fall under the Health Care Equipment & Services industry group, but CAH is classified in Health Care Providers & Services while PEN is classified in Health Care Equipment & Supplies.

Company profile comparison for Cardinal Health (CAH) and Penumbra (PEN)
Profile Item	CAH	PEN
Name	Cardinal Health, Inc.	Penumbra Inc.
Country/Region	United States	United States
GICS Sector	Health Care	Health Care
GICS Industry Group	Health Care Equipment & Services	Health Care Equipment & Services
GICS Industry	Health Care Providers & Services	Health Care Equipment & Supplies
GICS Sub-Industry	Health Care Distributors	Health Care Equipment
Market Capitalization	62.80 billion USD	12.58 billion USD
Currency	USD	USD
Exchange	NYSE	NYSE
Listing Date	August 4, 1983	September 18, 2015
Security Type	Common Stock	Common Stock

Price Performance

Cumulative Growth

CAH

PEN

GSPC

Cardinal Health (CAH) vs. Penumbra (PEN), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Cardinal Health (CAH) and Penumbra (PEN). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Cardinal Health (CAH) and Penumbra (PEN). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Cardinal Health (CAH) and Penumbra (PEN)
Metric	CAH	PEN
Total Return (1Y)	35.44%	20.52%
Total Return (3Y, Annualized)	40.52%	20.38%
Total Return (5Y, Annualized)	43.73%	3.15%

Risk Profile

Drawdown History

CAH

PEN

GSPC

Cardinal Health (CAH) vs. Penumbra (PEN), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Cardinal Health (CAH) and Penumbra (PEN). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Cardinal Health (CAH) and Penumbra (PEN)
Metric	CAH	PEN
Volatility (1Y, Annualized)	25.91%	19.78%
Beta (5Y)	0.49	0.68
Max Drawdown (5Y)	-20.95%	-59.60%
Avg. Volume (3M)	1.77M	348.64K

Risk-Adjusted Performance

Risk-Return Positioning

CAH and PEN are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Cardinal Health (CAH) and Penumbra (PEN)
Metric	CAH	PEN
Sharpe Ratio (1Y)	1.20	0.82
Sortino Ratio (1Y)	1.90	1.56

Profitability

ROE (TTM)

Capital efficiency shows on one side only: Penumbra (PEN) earns 10.67% on shareholders’ equity, ranked against its industry; Cardinal Health (CAH) has no ROE this period.

CAH

Health Care Equipment & Services industry group

Max: 47.61%
Q3: 14.36%
Median: 5.45%
Q1: -10.67%
Min: -47.01%
CAH: --

PEN

Health Care Equipment & Services industry group

10.67%

Max: 47.61%
Q3: 14.36%
PEN: 10.67%
Median: 5.45%
Q1: -10.67%
Min: -47.01%

Cardinal Health (CAH) vs. Penumbra (PEN): CAH does not report ROE, so it has no value marker; PEN is benchmarked against the Health Care Equipment & Services industry group.

Net Margin (TTM)

Penumbra (PEN) at 10.06% retains a top-quartile share of revenue as profit, ahead of Cardinal Health (CAH) at 0.71%, which keeps about the industry-typical share.

CAH

Health Care Equipment & Services industry group

0.71%

Max: 29.35%
Q3: 9.33%
Median: 2.18%
CAH: 0.71%
Q1: -6.29%
Min: -28.46%

PEN

Health Care Equipment & Services industry group

10.06%

Max: 29.35%
PEN: 10.06%
Q3: 9.33%
Median: 2.18%
Q1: -6.29%
Min: -28.46%

Cardinal Health (CAH) vs. Penumbra (PEN): A comparison of their net margin against the Health Care Equipment & Services industry group benchmark.

Operating Margin (TTM)

Both Cardinal Health (CAH) at 1.34% and Penumbra (PEN) at 12.37% run core operations about as efficiently as their industries’ norm — neither stands out on operating profitability.

CAH

Health Care Equipment & Services industry group

1.34%

Max: 35.43%
Q3: 14.14%
Median: 6.81%
CAH: 1.34%
Q1: -0.28%
Min: -16.29%

PEN

Health Care Equipment & Services industry group

12.37%

Max: 35.43%
Q3: 14.14%
PEN: 12.37%
Median: 6.81%
Q1: -0.28%
Min: -16.29%

Cardinal Health (CAH) vs. Penumbra (PEN): A comparison of their operating margin against the Health Care Equipment & Services industry group benchmark.

Profitability Metrics

Profitability metrics for Cardinal Health (CAH) and Penumbra (PEN)
Metric	CAH	PEN
ROE (TTM)	--	10.67%
ROA (TTM)	3.72%	6.28%
Net Margin (TTM)	0.71%	10.06%
Operating Margin (TTM)	1.34%	12.37%
Gross Margin (TTM)	3.90%	67.99%

Growth

Revenue Growth

Both Cardinal Health (CAH) at 14.23% and Penumbra (PEN) at 17.50% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

Cardinal Health (CAH) vs. Penumbra (PEN): A comparison of their Revenue Growth across different time periods.

EPS Growth

Penumbra (PEN) at 1,155.56% clears its industry range for EPS growth, a much stronger earnings trajectory than Cardinal Health (CAH) at 12.09%, which is closer to a typical peer reading.

Cardinal Health (CAH) vs. Penumbra (PEN): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Cardinal Health (CAH) and Penumbra (PEN)
Metric	CAH	PEN
Revenue Growth (YoY)	14.23%	17.50%
Revenue Growth (3Y CAGR)	7.44%	18.33%
EPS Growth (YoY)	12.09%	1,155.56%
EPS Growth (3Y CAGR)	93.37%	--

Financial Strength

Current Ratio (MRQ)

Penumbra (PEN) at 5.89 carries current ratio above its industry’s typical mid-range, while Cardinal Health (CAH) at 0.89 runs in the tighter-liquidity quartile — different working-capital profiles, both worth examining.

CAH

Health Care Equipment & Services industry group

0.89

Max: 7.59
Q3: 4.00
Median: 1.98
Q1: 1.37
CAH: 0.89
Min: 0.30

PEN

Health Care Equipment & Services industry group

5.89

Max: 7.59
PEN: 5.89
Q3: 4.00
Median: 1.98
Q1: 1.37
Min: 0.30

Cardinal Health (CAH) vs. Penumbra (PEN): A comparison of their current ratio against the Health Care Equipment & Services industry group benchmark.

Debt / Equity (MRQ)

Only one side’s leverage can be read here: Penumbra (PEN) carries debt-to-equity ratio of 0.13 against its industry range, while Cardinal Health (CAH) reports no figure this period.

CAH

Health Care Equipment & Services industry group

Max: 1.88
Q3: 0.91
Median: 0.58
Q1: 0.16
Min: 0.00
CAH: --

PEN

Health Care Equipment & Services industry group

0.13

Max: 1.88
Q3: 0.91
Median: 0.58
Q1: 0.16
PEN: 0.13
Min: 0.00

Cardinal Health (CAH) vs. Penumbra (PEN): CAH does not report debt-to-equity ratio, so it has no value marker; PEN is benchmarked against the Health Care Equipment & Services industry group.

Financial Strength Metrics

Financial strength metrics for Cardinal Health (CAH) and Penumbra (PEN)
Metric	CAH	PEN
Current Ratio (MRQ)	0.89	5.89
Debt / Equity (MRQ)	--	0.13
Net Debt / EBITDA	0.81	-2.22

Dividends

Dividend Yield (TTM)

Penumbra (PEN) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Cardinal Health (CAH) reports a yield of 0.77%, ranking against industry peers normally.

CAH

Health Care Equipment & Services industry group

0.77%

CAH: 0.77%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

PEN

Health Care Equipment & Services industry group

0.00%

PEN: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Cardinal Health (CAH) vs. Penumbra (PEN): A comparison of their dividend yield against the Health Care Equipment & Services industry group benchmark.

Dividend Payout Ratio (TTM)

Penumbra (PEN) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Cardinal Health (CAH) reports a payout of 26.56%, ranking against industry peers normally.

CAH

Health Care Equipment & Services industry group

26.56%

CAH: 26.56%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

PEN

Health Care Equipment & Services industry group

0.00%

PEN: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Cardinal Health (CAH) vs. Penumbra (PEN): A comparison of their payout ratio against the Health Care Equipment & Services industry group benchmark.

Dividend Metrics

Dividend metrics for Cardinal Health (CAH) and Penumbra (PEN)
Metric	CAH	PEN
Dividend Yield (TTM)	0.77%	0.00%
Dividend Payout Ratio (TTM)	26.56%	0.00%

Valuation

P/E Ratio (TTM)

Cardinal Health (CAH) at 35.15 is near its industry’s usual P/E ratio, while Penumbra (PEN) at 80.41 sits in the richer quartile — PEN needs stronger growth or earnings quality to justify the premium.

CAH

Health Care Equipment & Services industry group

35.15

Max: 80.41
Q3: 47.62
CAH: 35.15
Median: 29.93
Q1: 21.19
Min: 4.21

PEN

Health Care Equipment & Services industry group

80.41

PEN: 80.41
Max: 80.41
Q3: 47.62
Median: 29.93
Q1: 21.19
Min: 4.21

Cardinal Health (CAH) vs. Penumbra (PEN): A comparison of their P/E ratio against the Health Care Equipment & Services industry group benchmark.

P/S Ratio (TTM)

Cardinal Health (CAH) at 0.24 looks cheap on sales in the lower P/S ratio quartile, while Penumbra (PEN) at 8.06 looks rich in the upper quartile — a clear gap in price per dollar of revenue.

CAH

Health Care Equipment & Services industry group

0.24

Max: 8.80
Q3: 4.32
Median: 2.13
Q1: 1.10
CAH: 0.24
Min: 0.03

PEN

Health Care Equipment & Services industry group

8.06

Max: 8.80
PEN: 8.06
Q3: 4.32
Median: 2.13
Q1: 1.10
Min: 0.03

Cardinal Health (CAH) vs. Penumbra (PEN): A comparison of their P/S ratio against the Health Care Equipment & Services industry group benchmark.

P/B Ratio (MRQ)

Cardinal Health (CAH) reports a negative P/B ratio of -20.84, meaning negative book equity — the multiple itself is not meaningful for valuation. Meanwhile Penumbra (PEN) reports 7.95, ranking against industry peers normally.

CAH

Health Care Equipment & Services industry group

-20.84

Max: 11.68
Q3: 6.12
Median: 3.00
Q1: 1.73
Min: -1.31
CAH: -20.84

PEN

Health Care Equipment & Services industry group

7.95

Max: 11.68
PEN: 7.95
Q3: 6.12
Median: 3.00
Q1: 1.73
Min: -1.31

Cardinal Health (CAH) vs. Penumbra (PEN): A comparison of their P/B ratio against the Health Care Equipment & Services industry group benchmark.

Valuation Metrics

Valuation metrics for Cardinal Health (CAH) and Penumbra (PEN)
Metric	CAH	PEN
P/E Ratio (TTM)	35.15	80.41
P/S Ratio (TTM)	0.24	8.06
P/B Ratio (MRQ)	-20.84	7.95
Free Cash Flow Yield (TTM)	7.99%	1.32%