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BMRN vs. RGEN: BioMarin Pharmaceutical vs. Repligen Stock Comparison

How do BioMarin Pharmaceutical (BMRN) and Repligen (RGEN) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

BioMarin Pharmaceutical (BMRN) and Repligen (RGEN) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but BMRN is classified in Biotechnology while RGEN is classified in Life Sciences Tools & Services.

Company profile comparison for BioMarin Pharmaceutical (BMRN) and Repligen (RGEN)
Profile ItemBMRNRGEN
NameBioMarin Pharmaceutical Inc.Repligen Corporation
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyLife Sciences Tools & Services
GICS Sub-IndustryBiotechnologyLife Sciences Tools & Services
Market Capitalization10.85 billion USD11.09 billion USD
CurrencyUSDUSD
ExchangeNasdaqNasdaq
Listing DateJuly 26, 1999April 29, 1986
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

BMRN
RGEN
GSPC
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BioMarin Pharmaceutical (BMRN) vs. Repligen (RGEN), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for BioMarin Pharmaceutical (BMRN) and Repligen (RGEN). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for BioMarin Pharmaceutical (BMRN) and Repligen (RGEN). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for BioMarin Pharmaceutical (BMRN) and Repligen (RGEN)
MetricBMRNRGEN
Total Return (1Y)8.82%23.28%
Total Return (3Y, Annualized)-12.54%6.20%
Total Return (5Y, Annualized)-7.51%-8.41%

Risk Profile

Drawdown History

BMRN
RGEN
GSPC
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BioMarin Pharmaceutical (BMRN) vs. Repligen (RGEN), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for BioMarin Pharmaceutical (BMRN) and Repligen (RGEN). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for BioMarin Pharmaceutical (BMRN) and Repligen (RGEN)
MetricBMRNRGEN
Volatility (1Y, Annualized)35.50%46.73%
Beta (5Y)0.241.11
Max Drawdown (5Y)-57.64%-64.67%
Avg. Volume (3M)2.28M1.18M

Risk-Adjusted Performance

Risk-Return Positioning

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BMRN and RGEN are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for BioMarin Pharmaceutical (BMRN) and Repligen (RGEN)
MetricBMRNRGEN
Sharpe Ratio (1Y)0.130.41
Sortino Ratio (1Y)0.230.60

Profitability

ROE (TTM)

Both BioMarin Pharmaceutical (BMRN) at -0.31% and Repligen (RGEN) at -0.57% report negative ROE values. Negative ROE can reflect losses or negative shareholders’ equity, so both readings need extra context.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

-0.31%

Max
109.18%
Q3
6.23%
BMRN
-0.31%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

-0.57%

Max
109.18%
Q3
6.23%
RGEN
-0.57%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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BioMarin Pharmaceutical (BMRN) vs. Repligen (RGEN): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Both BioMarin Pharmaceutical (BMRN) at -0.52% and Repligen (RGEN) at -1.47% report negative net margin values, usually indicating net losses over the period.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

-0.52%

Max
18.05%
Q3
4.78%
Median
0.00%
BMRN
-0.52%
Q1
-4.14%
Min
-17.05%

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

-1.47%

Max
18.05%
Q3
4.78%
Median
0.00%
RGEN
-1.47%
Q1
-4.14%
Min
-17.05%
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BioMarin Pharmaceutical (BMRN) vs. Repligen (RGEN): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

BioMarin Pharmaceutical (BMRN) at 26.58% operates in the top operating margin quartile, ahead of Repligen (RGEN) at 6.19%, which runs around its industry’s norm.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

26.58%

Max
83.12%
BMRN
26.58%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.19%

Max
83.12%
Q3
14.77%
RGEN
6.19%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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BioMarin Pharmaceutical (BMRN) vs. Repligen (RGEN): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for BioMarin Pharmaceutical (BMRN) and Repligen (RGEN)
MetricBMRNRGEN
ROE (TTM)-0.31%-0.57%
ROA (TTM)3.89%1.40%
Net Margin (TTM)-0.52%-1.47%
Operating Margin (TTM)26.58%6.19%
Gross Margin (TTM)53.21%53.77%

Growth

Revenue Growth

Both BioMarin Pharmaceutical (BMRN) at 12.87% and Repligen (RGEN) at 16.36% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

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BioMarin Pharmaceutical (BMRN) vs. Repligen (RGEN): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: BioMarin Pharmaceutical (BMRN) reports EPS growth of -18.55%, ranked against its industry; Repligen (RGEN) has no EPS growth figure this period.

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BioMarin Pharmaceutical (BMRN) vs. Repligen (RGEN): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for BioMarin Pharmaceutical (BMRN) and Repligen (RGEN)
MetricBMRNRGEN
Revenue Growth (YoY)12.87%16.36%
Revenue Growth (3Y CAGR)15.40%-2.70%
EPS Growth (YoY)-18.55%--
EPS Growth (3Y CAGR)33.89%-35.73%

Financial Strength

Current Ratio (MRQ)

Repligen (RGEN) at 9.88 keeps current ratio within its industry’s typical mid-range, while BioMarin Pharmaceutical (BMRN) at 2.44 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for BMRN.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.44

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
BMRN
2.44
Min
0.10

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

9.88

Max
25.13
Q3
12.13
RGEN
9.88
Median
5.52
Q1
2.47
Min
0.10
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BioMarin Pharmaceutical (BMRN) vs. Repligen (RGEN): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Repligen (RGEN) at 0.33 carries an industry-typical debt-to-equity mix, while BioMarin Pharmaceutical (BMRN) at 0.67 uses more debt funding than most peers.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.67

Max
1.42
BMRN
0.67
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.33

Max
1.42
Q3
0.65
RGEN
0.33
Median
0.15
Q1
0.02
Min
0.00
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BioMarin Pharmaceutical (BMRN) vs. Repligen (RGEN): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for BioMarin Pharmaceutical (BMRN) and Repligen (RGEN)
MetricBMRNRGEN
Current Ratio (MRQ)2.449.88
Debt / Equity (MRQ)0.670.33
Net Debt / EBITDA4.04-1.19

Dividends

Dividend Yield (TTM)

Neither BioMarin Pharmaceutical (BMRN) nor Repligen (RGEN) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

BMRN
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

RGEN
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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BioMarin Pharmaceutical (BMRN) vs. Repligen (RGEN): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Neither BioMarin Pharmaceutical (BMRN) nor Repligen (RGEN) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

BMRN
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

RGEN
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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BioMarin Pharmaceutical (BMRN) vs. Repligen (RGEN): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for BioMarin Pharmaceutical (BMRN) and Repligen (RGEN)
MetricBMRNRGEN
Dividend Yield (TTM)0.00%0.00%
Dividend Payout Ratio (TTM)0.00%0.00%

Valuation

P/E Ratio (TTM)

Neither BioMarin Pharmaceutical (BMRN) nor Repligen (RGEN) reports a P/E ratio value for this period, so a direct comparison isn’t possible.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
BMRN
--

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
RGEN
--
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BioMarin Pharmaceutical (BMRN) vs. Repligen (RGEN): Neither stock reports P/E ratio, so the chart shows available benchmark boxes without value markers.

P/S Ratio (TTM)

BioMarin Pharmaceutical (BMRN) at 2.97 sits in the cheaper P/S ratio quartile while Repligen (RGEN) at 13.77 prices around its industry’s middle — BMRN costs less per dollar of sales, though read it alongside growth and margins.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.97

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
BMRN
2.97
Min
0.01

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

13.77

Max
58.18
Q3
25.77
RGEN
13.77
Median
7.30
Q1
3.01
Min
0.01
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BioMarin Pharmaceutical (BMRN) vs. Repligen (RGEN): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

On P/B ratio, both BioMarin Pharmaceutical (BMRN) at 1.73 and Repligen (RGEN) at 4.70 are valued close to their industries’ norm against book — neither stands out from peers.

BMRN

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.73

Max
13.53
Q3
6.54
Median
3.25
BMRN
1.73
Q1
1.69
Min
-5.59

RGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.70

Max
13.53
Q3
6.54
RGEN
4.70
Median
3.25
Q1
1.69
Min
-5.59
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BioMarin Pharmaceutical (BMRN) vs. Repligen (RGEN): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for BioMarin Pharmaceutical (BMRN) and Repligen (RGEN)
MetricBMRNRGEN
P/E Ratio (TTM)----
P/S Ratio (TTM)2.9713.77
P/B Ratio (MRQ)1.734.70
Free Cash Flow Yield (TTM)-0.15%1.01%