TAK vs. WAT: Takeda Pharmaceutical vs. Waters Stock Comparison
How do Takeda Pharmaceutical (TAK) and Waters (WAT) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.
Company Profile
Takeda Pharmaceutical (TAK) and Waters (WAT) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but TAK is classified in Pharmaceuticals while WAT is classified in Life Sciences Tools & Services.
Waters (WAT) trades as ordinary local shares, while Takeda Pharmaceutical (TAK) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.
| Profile Item | TAK | WAT |
|---|---|---|
| Name | Takeda Pharmaceutical Co Ltd ADR | Waters Corporation |
| Country/Region | Japan | United States |
| GICS Sector | Health Care | Health Care |
| GICS Industry Group | Pharmaceuticals, Biotechnology & Life Sciences | Pharmaceuticals, Biotechnology & Life Sciences |
| GICS Industry | Pharmaceuticals | Life Sciences Tools & Services |
| GICS Sub-Industry | Pharmaceuticals | Life Sciences Tools & Services |
| Market Capitalization | 67.16 billion USD | 44.93 billion USD |
| Currency | USD | USD |
| Exchange | NYSE | NYSE |
| Listing Date | January 5, 2010 | November 17, 1995 |
| Security Type | ADR | Common Stock |
Price Performance
Cumulative Growth
Trailing Returns
Calendar-Year Returns
Performance Metrics
| Metric | TAK | WAT |
|---|---|---|
| Total Return (1Y) | 54.54% | 27.70% |
| Total Return (3Y, Annualized) | 18.39% | 23.32% |
| Total Return (5Y, Annualized) | 9.29% | 6.27% |
Risk Profile
Drawdown History
Return Distribution
Risk Metrics
Takeda Pharmaceutical (TAK) reports a negative beta of -0.01, suggesting inverse market sensitivity over the measurement window. That is uncommon for ordinary equities and can reflect commodity-linked or hedge-like exposure, but it can also come from statistical noise. Waters (WAT) has a non-negative beta of 1.13.
| Metric | TAK | WAT |
|---|---|---|
| Volatility (1Y, Annualized) | 21.45% | 35.45% |
| Beta (5Y) | -0.01 | 1.13 |
| Max Drawdown (5Y) | -24.83% | -36.47% |
| Avg. Volume (3M) | 2.61M | 816.72K |
Risk-Adjusted Performance
Risk-Return Positioning
Risk-Adjusted Metrics
| Metric | TAK | WAT |
|---|---|---|
| Sharpe Ratio (1Y) | 2.34 | 0.66 |
| Sortino Ratio (1Y) | 3.88 | 0.98 |
Profitability
ROE (TTM)
Both Takeda Pharmaceutical (TAK) at 0.56% and Waters (WAT) at 1.12% land near their industries’ usual ROE ranges, so capital efficiency looks broadly in line with peers on both sides.
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.56%
- Max
- 109.18%
- Q3
- 6.23%
- TAK
- 0.56%
- Median
- -26.66%
- Q1
- -64.05%
- Min
- -167.77%
WAT
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.12%
- Max
- 109.18%
- Q3
- 6.23%
- WAT
- 1.12%
- Median
- -26.66%
- Q1
- -64.05%
- Min
- -167.77%
Net Margin (TTM)
Both Takeda Pharmaceutical (TAK) at 0.87% and Waters (WAT) at 1.76% keep about the typical share of revenue as profit for their industries — neither bottom line stands out from peers.
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.87%
- Max
- 18.05%
- Q3
- 4.78%
- TAK
- 0.87%
- Median
- 0.00%
- Q1
- -4.14%
- Min
- -17.05%
WAT
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.76%
- Max
- 18.05%
- Q3
- 4.78%
- WAT
- 1.76%
- Median
- 0.00%
- Q1
- -4.14%
- Min
- -17.05%
Operating Margin (TTM)
Takeda Pharmaceutical (TAK) at 24.55% operates in the top operating margin quartile, ahead of Waters (WAT) at 11.38%, which runs around its industry’s norm.
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
24.55%
- Max
- 83.12%
- TAK
- 24.55%
- Q3
- 14.77%
- Median
- 0.00%
- Q1
- -78.82%
- Min
- -207.40%
WAT
Pharmaceuticals, Biotechnology & Life Sciences industry group
11.38%
- Max
- 83.12%
- Q3
- 14.77%
- WAT
- 11.38%
- Median
- 0.00%
- Q1
- -78.82%
- Min
- -207.40%
Profitability Metrics
| Metric | TAK | WAT |
|---|---|---|
| ROE (TTM) | 0.56% | 1.12% |
| ROA (TTM) | 3.27% | 2.36% |
| Net Margin (TTM) | 0.87% | 1.76% |
| Operating Margin (TTM) | 24.55% | 11.38% |
| Gross Margin (TTM) | 64.77% | 49.83% |
Growth
Revenue Growth
Waters (WAT) at 6.99% is around its peer norm for revenue growth, while Takeda Pharmaceutical (TAK) at -1.66% drops into the bottom quartile, signaling weaker demand or pricing momentum.
EPS Growth
Takeda Pharmaceutical (TAK) at 77.96% sits in the top EPS growth quartile, while Waters (WAT) at 0.47% is closer to the peer norm — faster per-share earnings growth for TAK.
Growth Metrics
| Metric | TAK | WAT |
|---|---|---|
| Revenue Growth (YoY) | -1.66% | 6.99% |
| Revenue Growth (3Y CAGR) | 3.81% | 2.12% |
| EPS Growth (YoY) | 77.96% | 0.47% |
| EPS Growth (3Y CAGR) | -16.01% | -2.84% |
Financial Strength
Current Ratio (MRQ)
Short-term liquidity can only be read on one side of this pairing: Takeda Pharmaceutical (TAK) shows current ratio of 1.15 against its industry benchmark, while Waters (WAT) has no reading this period.
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.15
- Max
- 25.13
- Q3
- 12.13
- Median
- 5.52
- Q1
- 2.47
- TAK
- 1.15
- Min
- 0.10
WAT
Pharmaceuticals, Biotechnology & Life Sciences industry group
--
- Max
- 25.13
- Q3
- 12.13
- Median
- 5.52
- Q1
- 2.47
- Min
- 0.10
- WAT
- --
Debt / Equity (MRQ)
Waters (WAT) at 0.34 carries an industry-typical debt-to-equity mix, while Takeda Pharmaceutical (TAK) at 0.72 uses more debt funding than most peers.
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.72
- Max
- 1.42
- TAK
- 0.72
- Q3
- 0.65
- Median
- 0.15
- Q1
- 0.02
- Min
- 0.00
WAT
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.34
- Max
- 1.42
- Q3
- 0.65
- WAT
- 0.34
- Median
- 0.15
- Q1
- 0.02
- Min
- 0.00
Financial Strength Metrics
| Metric | TAK | WAT |
|---|---|---|
| Current Ratio (MRQ) | 1.15 | -- |
| Debt / Equity (MRQ) | 0.72 | 0.34 |
| Net Debt / EBITDA | 3.61 | 3.23 |
Dividends
Dividend Yield (TTM)
Waters (WAT) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Takeda Pharmaceutical (TAK) reports a yield of 953.28%, ranking against industry peers normally.
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
953.28%
- TAK
- 953.28%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
WAT
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.00%
- WAT
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Payout Ratio (TTM)
Takeda Pharmaceutical (TAK) reports payout ratio above 100% at 426.53%, meaning dividends exceeded current-period earnings; Waters (WAT) pays no dividend (payout 0.00%).
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
426.53%
- TAK
- 426.53%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
WAT
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.00%
- WAT
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Metrics
| Metric | TAK | WAT |
|---|---|---|
| Dividend Yield (TTM) | 953.28% | 0.00% |
| Dividend Payout Ratio (TTM) | 426.53% | 0.00% |
Valuation
P/E Ratio (TTM)
Both Takeda Pharmaceutical (TAK) at 300.29 and Waters (WAT) at 191.46 trade above their industries’ P/E ratio peer ranges, pointing to unusually expensive trailing earnings relative to peers.
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
300.29
- TAK
- 300.29
- Max
- 85.34
- Q3
- 43.46
- Median
- 26.69
- Q1
- 13.30
- Min
- 0.07
WAT
Pharmaceuticals, Biotechnology & Life Sciences industry group
191.46
- WAT
- 191.46
- Max
- 85.34
- Q3
- 43.46
- Median
- 26.69
- Q1
- 13.30
- Min
- 0.07
P/S Ratio (TTM)
Takeda Pharmaceutical (TAK) at 0.01 sits in the cheaper P/S ratio quartile while Waters (WAT) at 8.01 prices around its industry’s middle — TAK costs less per dollar of sales, though read it alongside growth and margins.
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.01
- Max
- 58.18
- Q3
- 25.77
- Median
- 7.30
- Q1
- 3.01
- TAK
- 0.01
- Min
- 0.01
WAT
Pharmaceuticals, Biotechnology & Life Sciences industry group
8.01
- Max
- 58.18
- Q3
- 25.77
- WAT
- 8.01
- Median
- 7.30
- Q1
- 3.01
- Min
- 0.01
P/B Ratio (MRQ)
Takeda Pharmaceutical (TAK) at 1.43 sits in the lower P/B ratio quartile against book while Waters (WAT) at 2.94 is valued near its industry’s middle — TAK is cheaper on assets, though weigh it against ROE and asset quality.
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.43
- Max
- 13.53
- Q3
- 6.54
- Median
- 3.25
- Q1
- 1.69
- TAK
- 1.43
- Min
- -5.59
WAT
Pharmaceuticals, Biotechnology & Life Sciences industry group
2.94
- Max
- 13.53
- Q3
- 6.54
- Median
- 3.25
- WAT
- 2.94
- Q1
- 1.69
- Min
- -5.59
Valuation Metrics
| Metric | TAK | WAT |
|---|---|---|
| P/E Ratio (TTM) | 300.29 | 191.46 |
| P/S Ratio (TTM) | 0.01 | 8.01 |
| P/B Ratio (MRQ) | 1.43 | 2.94 |
| Free Cash Flow Yield (TTM) | 1,014.61% | -- |