TAK vs. TECH: Takeda Pharmaceutical vs. Bio-Techne Stock Comparison
How do Takeda Pharmaceutical (TAK) and Bio-Techne (TECH) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.
Company Profile
Takeda Pharmaceutical (TAK) and Bio-Techne (TECH) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but TAK is classified in Pharmaceuticals while TECH is classified in Life Sciences Tools & Services.
Bio-Techne (TECH) trades as ordinary local shares, while Takeda Pharmaceutical (TAK) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.
| Profile Item | TAK | TECH |
|---|---|---|
| Name | Takeda Pharmaceutical Co Ltd ADR | Bio-Techne Corp. |
| Country/Region | Japan | United States |
| GICS Sector | Health Care | Health Care |
| GICS Industry Group | Pharmaceuticals, Biotechnology & Life Sciences | Pharmaceuticals, Biotechnology & Life Sciences |
| GICS Industry | Pharmaceuticals | Life Sciences Tools & Services |
| GICS Sub-Industry | Pharmaceuticals | Life Sciences Tools & Services |
| Market Capitalization | 67.16 billion USD | 11.43 billion USD |
| Currency | USD | USD |
| Exchange | NYSE | Nasdaq |
| Listing Date | January 5, 2010 | February 9, 1989 |
| Security Type | ADR | Common Stock |
Price Performance
Cumulative Growth
Trailing Returns
Calendar-Year Returns
Performance Metrics
| Metric | TAK | TECH |
|---|---|---|
| Total Return (1Y) | 54.54% | 27.56% |
| Total Return (3Y, Annualized) | 18.39% | 9.11% |
| Total Return (5Y, Annualized) | 9.29% | -9.91% |
Risk Profile
Drawdown History
Return Distribution
Risk Metrics
Takeda Pharmaceutical (TAK) reports a negative beta of -0.01, suggesting inverse market sensitivity over the measurement window. That is uncommon for ordinary equities and can reflect commodity-linked or hedge-like exposure, but it can also come from statistical noise. Bio-Techne (TECH) has a non-negative beta of 1.26.
| Metric | TAK | TECH |
|---|---|---|
| Volatility (1Y, Annualized) | 21.45% | 43.08% |
| Beta (5Y) | -0.01 | 1.26 |
| Max Drawdown (5Y) | -24.83% | -65.87% |
| Avg. Volume (3M) | 2.61M | 2.81M |
Risk-Adjusted Performance
Risk-Return Positioning
Risk-Adjusted Metrics
| Metric | TAK | TECH |
|---|---|---|
| Sharpe Ratio (1Y) | 2.34 | 0.54 |
| Sortino Ratio (1Y) | 3.88 | 0.82 |
Profitability
ROE (TTM)
Bio-Techne (TECH) at 8.33% sits in the top ROE quartile, while Takeda Pharmaceutical (TAK) at 0.56% is closer to the peer norm — stronger capital efficiency for TECH.
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.56%
- Max
- 109.18%
- Q3
- 6.23%
- TAK
- 0.56%
- Median
- -26.66%
- Q1
- -64.05%
- Min
- -167.77%
TECH
Pharmaceuticals, Biotechnology & Life Sciences industry group
8.33%
- Max
- 109.18%
- TECH
- 8.33%
- Q3
- 6.23%
- Median
- -26.66%
- Q1
- -64.05%
- Min
- -167.77%
Net Margin (TTM)
Bio-Techne (TECH) at 14.00% retains a top-quartile share of revenue as profit, ahead of Takeda Pharmaceutical (TAK) at 0.87%, which keeps about the industry-typical share.
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.87%
- Max
- 18.05%
- Q3
- 4.78%
- TAK
- 0.87%
- Median
- 0.00%
- Q1
- -4.14%
- Min
- -17.05%
TECH
Pharmaceuticals, Biotechnology & Life Sciences industry group
14.00%
- Max
- 18.05%
- TECH
- 14.00%
- Q3
- 4.78%
- Median
- 0.00%
- Q1
- -4.14%
- Min
- -17.05%
Operating Margin (TTM)
Takeda Pharmaceutical (TAK) at 24.55% operates in the top operating margin quartile, ahead of Bio-Techne (TECH) at 12.21%, which runs around its industry’s norm.
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
24.55%
- Max
- 83.12%
- TAK
- 24.55%
- Q3
- 14.77%
- Median
- 0.00%
- Q1
- -78.82%
- Min
- -207.40%
TECH
Pharmaceuticals, Biotechnology & Life Sciences industry group
12.21%
- Max
- 83.12%
- Q3
- 14.77%
- TECH
- 12.21%
- Median
- 0.00%
- Q1
- -78.82%
- Min
- -207.40%
Profitability Metrics
| Metric | TAK | TECH |
|---|---|---|
| ROE (TTM) | 0.56% | 8.33% |
| ROA (TTM) | 3.27% | 6.38% |
| Net Margin (TTM) | 0.87% | 14.00% |
| Operating Margin (TTM) | 24.55% | 12.21% |
| Gross Margin (TTM) | 64.77% | 66.23% |
Growth
Revenue Growth
Bio-Techne (TECH) at -0.38% is around its peer norm for revenue growth, while Takeda Pharmaceutical (TAK) at -1.66% drops into the bottom quartile, signaling weaker demand or pricing momentum.
EPS Growth
Both Takeda Pharmaceutical (TAK) at 77.96% and Bio-Techne (TECH) at 152.17% sit in the top peer quartile for EPS growth, so each is compounding per-share earnings faster than typical industry peers.
Growth Metrics
| Metric | TAK | TECH |
|---|---|---|
| Revenue Growth (YoY) | -1.66% | -0.38% |
| Revenue Growth (3Y CAGR) | 3.81% | 2.25% |
| EPS Growth (YoY) | 77.96% | 152.17% |
| EPS Growth (3Y CAGR) | -16.01% | -12.97% |
Financial Strength
Current Ratio (MRQ)
Both Takeda Pharmaceutical (TAK) at 1.15 and Bio-Techne (TECH) at 2.28 run current ratio in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.15
- Max
- 25.13
- Q3
- 12.13
- Median
- 5.52
- Q1
- 2.47
- TAK
- 1.15
- Min
- 0.10
TECH
Pharmaceuticals, Biotechnology & Life Sciences industry group
2.28
- Max
- 25.13
- Q3
- 12.13
- Median
- 5.52
- Q1
- 2.47
- TECH
- 2.28
- Min
- 0.10
Debt / Equity (MRQ)
Bio-Techne (TECH) at 0.13 carries an industry-typical debt-to-equity mix, while Takeda Pharmaceutical (TAK) at 0.72 uses more debt funding than most peers.
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.72
- Max
- 1.42
- TAK
- 0.72
- Q3
- 0.65
- Median
- 0.15
- Q1
- 0.02
- Min
- 0.00
TECH
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.13
- Max
- 1.42
- Q3
- 0.65
- Median
- 0.15
- TECH
- 0.13
- Q1
- 0.02
- Min
- 0.00
Financial Strength Metrics
| Metric | TAK | TECH |
|---|---|---|
| Current Ratio (MRQ) | 1.15 | 2.28 |
| Debt / Equity (MRQ) | 0.72 | 0.13 |
| Net Debt / EBITDA | 3.61 | -0.20 |
Dividends
Dividend Yield (TTM)
Both Takeda Pharmaceutical (TAK) at 953.28% and Bio-Techne (TECH) at 0.44% yield above their industries’ entire benchmark ranges — high enough that dividend safety, not income, becomes the first question.
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
953.28%
- TAK
- 953.28%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
TECH
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.44%
- TECH
- 0.44%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Payout Ratio (TTM)
Takeda Pharmaceutical (TAK) reports payout ratio above 100% at 426.53%, meaning dividends exceeded current-period earnings and sustainability needs extra context. Meanwhile Bio-Techne (TECH) reports 27.59%, ranking against industry peers normally.
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
426.53%
- TAK
- 426.53%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
TECH
Pharmaceuticals, Biotechnology & Life Sciences industry group
27.59%
- TECH
- 27.59%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Metrics
| Metric | TAK | TECH |
|---|---|---|
| Dividend Yield (TTM) | 953.28% | 0.44% |
| Dividend Payout Ratio (TTM) | 426.53% | 27.59% |
Valuation
P/E Ratio (TTM)
Both look expensive on trailing earnings: Bio-Techne (TECH) at 62.74 sits in the richer P/E ratio quartile, and Takeda Pharmaceutical (TAK) at 300.29 is richer still, above its industry range.
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
300.29
- TAK
- 300.29
- Max
- 85.34
- Q3
- 43.46
- Median
- 26.69
- Q1
- 13.30
- Min
- 0.07
TECH
Pharmaceuticals, Biotechnology & Life Sciences industry group
62.74
- Max
- 85.34
- TECH
- 62.74
- Q3
- 43.46
- Median
- 26.69
- Q1
- 13.30
- Min
- 0.07
P/S Ratio (TTM)
Takeda Pharmaceutical (TAK) at 0.01 sits in the cheaper P/S ratio quartile while Bio-Techne (TECH) at 9.31 prices around its industry’s middle — TAK costs less per dollar of sales, though read it alongside growth and margins.
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.01
- Max
- 58.18
- Q3
- 25.77
- Median
- 7.30
- Q1
- 3.01
- TAK
- 0.01
- Min
- 0.01
TECH
Pharmaceuticals, Biotechnology & Life Sciences industry group
9.31
- Max
- 58.18
- Q3
- 25.77
- TECH
- 9.31
- Median
- 7.30
- Q1
- 3.01
- Min
- 0.01
P/B Ratio (MRQ)
Takeda Pharmaceutical (TAK) at 1.43 sits in the lower P/B ratio quartile against book while Bio-Techne (TECH) at 5.28 is valued near its industry’s middle — TAK is cheaper on assets, though weigh it against ROE and asset quality.
TAK
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.43
- Max
- 13.53
- Q3
- 6.54
- Median
- 3.25
- Q1
- 1.69
- TAK
- 1.43
- Min
- -5.59
TECH
Pharmaceuticals, Biotechnology & Life Sciences industry group
5.28
- Max
- 13.53
- Q3
- 6.54
- TECH
- 5.28
- Median
- 3.25
- Q1
- 1.69
- Min
- -5.59
Valuation Metrics
| Metric | TAK | TECH |
|---|---|---|
| P/E Ratio (TTM) | 300.29 | 62.74 |
| P/S Ratio (TTM) | 0.01 | 9.31 |
| P/B Ratio (MRQ) | 1.43 | 5.28 |
| Free Cash Flow Yield (TTM) | 1,014.61% | 2.39% |