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TAK vs. TECH: Takeda Pharmaceutical vs. Bio-Techne Stock Comparison

How do Takeda Pharmaceutical (TAK) and Bio-Techne (TECH) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Takeda Pharmaceutical (TAK) and Bio-Techne (TECH) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but TAK is classified in Pharmaceuticals while TECH is classified in Life Sciences Tools & Services.

Bio-Techne (TECH) trades as ordinary local shares, while Takeda Pharmaceutical (TAK) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.

Company profile comparison for Takeda Pharmaceutical (TAK) and Bio-Techne (TECH)
Profile ItemTAKTECH
NameTakeda Pharmaceutical Co Ltd ADRBio-Techne Corp.
Country/RegionJapanUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryPharmaceuticalsLife Sciences Tools & Services
GICS Sub-IndustryPharmaceuticalsLife Sciences Tools & Services
Market Capitalization67.16 billion USD11.43 billion USD
CurrencyUSDUSD
ExchangeNYSENasdaq
Listing DateJanuary 5, 2010February 9, 1989
Security TypeADRCommon Stock

Price Performance

Cumulative Growth

TAK
TECH
GSPC
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Takeda Pharmaceutical (TAK) vs. Bio-Techne (TECH), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Takeda Pharmaceutical (TAK) and Bio-Techne (TECH). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Takeda Pharmaceutical (TAK) and Bio-Techne (TECH). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Takeda Pharmaceutical (TAK) and Bio-Techne (TECH)
MetricTAKTECH
Total Return (1Y)54.54%27.56%
Total Return (3Y, Annualized)18.39%9.11%
Total Return (5Y, Annualized)9.29%-9.91%

Risk Profile

Drawdown History

TAK
TECH
GSPC
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Takeda Pharmaceutical (TAK) vs. Bio-Techne (TECH), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Takeda Pharmaceutical (TAK) and Bio-Techne (TECH). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Takeda Pharmaceutical (TAK) reports a negative beta of -0.01, suggesting inverse market sensitivity over the measurement window. That is uncommon for ordinary equities and can reflect commodity-linked or hedge-like exposure, but it can also come from statistical noise. Bio-Techne (TECH) has a non-negative beta of 1.26.

Risk profile metrics for Takeda Pharmaceutical (TAK) and Bio-Techne (TECH)
MetricTAKTECH
Volatility (1Y, Annualized)21.45%43.08%
Beta (5Y)-0.011.26
Max Drawdown (5Y)-24.83%-65.87%
Avg. Volume (3M)2.61M2.81M

Risk-Adjusted Performance

Risk-Return Positioning

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TAK and TECH are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Takeda Pharmaceutical (TAK) and Bio-Techne (TECH)
MetricTAKTECH
Sharpe Ratio (1Y)2.340.54
Sortino Ratio (1Y)3.880.82

Profitability

ROE (TTM)

Bio-Techne (TECH) at 8.33% sits in the top ROE quartile, while Takeda Pharmaceutical (TAK) at 0.56% is closer to the peer norm — stronger capital efficiency for TECH.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.56%

Max
109.18%
Q3
6.23%
TAK
0.56%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

TECH

Pharmaceuticals, Biotechnology & Life Sciences industry group

8.33%

Max
109.18%
TECH
8.33%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Takeda Pharmaceutical (TAK) vs. Bio-Techne (TECH): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Bio-Techne (TECH) at 14.00% retains a top-quartile share of revenue as profit, ahead of Takeda Pharmaceutical (TAK) at 0.87%, which keeps about the industry-typical share.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.87%

Max
18.05%
Q3
4.78%
TAK
0.87%
Median
0.00%
Q1
-4.14%
Min
-17.05%

TECH

Pharmaceuticals, Biotechnology & Life Sciences industry group

14.00%

Max
18.05%
TECH
14.00%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Takeda Pharmaceutical (TAK) vs. Bio-Techne (TECH): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Takeda Pharmaceutical (TAK) at 24.55% operates in the top operating margin quartile, ahead of Bio-Techne (TECH) at 12.21%, which runs around its industry’s norm.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

24.55%

Max
83.12%
TAK
24.55%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

TECH

Pharmaceuticals, Biotechnology & Life Sciences industry group

12.21%

Max
83.12%
Q3
14.77%
TECH
12.21%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Takeda Pharmaceutical (TAK) vs. Bio-Techne (TECH): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Takeda Pharmaceutical (TAK) and Bio-Techne (TECH)
MetricTAKTECH
ROE (TTM)0.56%8.33%
ROA (TTM)3.27%6.38%
Net Margin (TTM)0.87%14.00%
Operating Margin (TTM)24.55%12.21%
Gross Margin (TTM)64.77%66.23%

Growth

Revenue Growth

Bio-Techne (TECH) at -0.38% is around its peer norm for revenue growth, while Takeda Pharmaceutical (TAK) at -1.66% drops into the bottom quartile, signaling weaker demand or pricing momentum.

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Takeda Pharmaceutical (TAK) vs. Bio-Techne (TECH): A comparison of their Revenue Growth across different time periods.

EPS Growth

Both Takeda Pharmaceutical (TAK) at 77.96% and Bio-Techne (TECH) at 152.17% sit in the top peer quartile for EPS growth, so each is compounding per-share earnings faster than typical industry peers.

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Takeda Pharmaceutical (TAK) vs. Bio-Techne (TECH): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Takeda Pharmaceutical (TAK) and Bio-Techne (TECH)
MetricTAKTECH
Revenue Growth (YoY)-1.66%-0.38%
Revenue Growth (3Y CAGR)3.81%2.25%
EPS Growth (YoY)77.96%152.17%
EPS Growth (3Y CAGR)-16.01%-12.97%

Financial Strength

Current Ratio (MRQ)

Both Takeda Pharmaceutical (TAK) at 1.15 and Bio-Techne (TECH) at 2.28 run current ratio in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.15

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
TAK
1.15
Min
0.10

TECH

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.28

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
TECH
2.28
Min
0.10
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Takeda Pharmaceutical (TAK) vs. Bio-Techne (TECH): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Bio-Techne (TECH) at 0.13 carries an industry-typical debt-to-equity mix, while Takeda Pharmaceutical (TAK) at 0.72 uses more debt funding than most peers.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.72

Max
1.42
TAK
0.72
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

TECH

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.13

Max
1.42
Q3
0.65
Median
0.15
TECH
0.13
Q1
0.02
Min
0.00
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Takeda Pharmaceutical (TAK) vs. Bio-Techne (TECH): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Takeda Pharmaceutical (TAK) and Bio-Techne (TECH)
MetricTAKTECH
Current Ratio (MRQ)1.152.28
Debt / Equity (MRQ)0.720.13
Net Debt / EBITDA3.61-0.20

Dividends

Dividend Yield (TTM)

Both Takeda Pharmaceutical (TAK) at 953.28% and Bio-Techne (TECH) at 0.44% yield above their industries’ entire benchmark ranges — high enough that dividend safety, not income, becomes the first question.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

953.28%

TAK
953.28%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

TECH

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.44%

TECH
0.44%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Takeda Pharmaceutical (TAK) vs. Bio-Techne (TECH): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Takeda Pharmaceutical (TAK) reports payout ratio above 100% at 426.53%, meaning dividends exceeded current-period earnings and sustainability needs extra context. Meanwhile Bio-Techne (TECH) reports 27.59%, ranking against industry peers normally.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

426.53%

TAK
426.53%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

TECH

Pharmaceuticals, Biotechnology & Life Sciences industry group

27.59%

TECH
27.59%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Takeda Pharmaceutical (TAK) vs. Bio-Techne (TECH): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Takeda Pharmaceutical (TAK) and Bio-Techne (TECH)
MetricTAKTECH
Dividend Yield (TTM)953.28%0.44%
Dividend Payout Ratio (TTM)426.53%27.59%

Valuation

P/E Ratio (TTM)

Both look expensive on trailing earnings: Bio-Techne (TECH) at 62.74 sits in the richer P/E ratio quartile, and Takeda Pharmaceutical (TAK) at 300.29 is richer still, above its industry range.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

300.29

TAK
300.29
Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07

TECH

Pharmaceuticals, Biotechnology & Life Sciences industry group

62.74

Max
85.34
TECH
62.74
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
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Takeda Pharmaceutical (TAK) vs. Bio-Techne (TECH): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

Takeda Pharmaceutical (TAK) at 0.01 sits in the cheaper P/S ratio quartile while Bio-Techne (TECH) at 9.31 prices around its industry’s middle — TAK costs less per dollar of sales, though read it alongside growth and margins.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.01

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
TAK
0.01
Min
0.01

TECH

Pharmaceuticals, Biotechnology & Life Sciences industry group

9.31

Max
58.18
Q3
25.77
TECH
9.31
Median
7.30
Q1
3.01
Min
0.01
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Takeda Pharmaceutical (TAK) vs. Bio-Techne (TECH): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Takeda Pharmaceutical (TAK) at 1.43 sits in the lower P/B ratio quartile against book while Bio-Techne (TECH) at 5.28 is valued near its industry’s middle — TAK is cheaper on assets, though weigh it against ROE and asset quality.

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.43

Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
TAK
1.43
Min
-5.59

TECH

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.28

Max
13.53
Q3
6.54
TECH
5.28
Median
3.25
Q1
1.69
Min
-5.59
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Takeda Pharmaceutical (TAK) vs. Bio-Techne (TECH): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Takeda Pharmaceutical (TAK) and Bio-Techne (TECH)
MetricTAKTECH
P/E Ratio (TTM)300.2962.74
P/S Ratio (TTM)0.019.31
P/B Ratio (MRQ)1.435.28
Free Cash Flow Yield (TTM)1,014.61%2.39%