Seek Returns

ROIV vs. VRTX: Roivant Sciences vs. Vertex Pharmaceuticals Stock Comparison

How do Roivant Sciences (ROIV) and Vertex Pharmaceuticals (VRTX) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Roivant Sciences (ROIV) and Vertex Pharmaceuticals (VRTX) are both classified in the Biotechnology sub-industry within the broader Biotechnology industry, placing them in the closest GICS peer bucket.

Vertex Pharmaceuticals (VRTX) has more than two decades of public-market history since July 24, 1991, whereas Roivant Sciences (ROIV) listed on December 8, 2020 and has a much shorter record to draw on.

Company profile comparison for Roivant Sciences (ROIV) and Vertex Pharmaceuticals (VRTX)
Profile ItemROIVVRTX
NameRoivant Sciences Ltd.Vertex Pharmaceuticals Incorporated Common Stock
Country/RegionUnited KingdomUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyBiotechnology
GICS Sub-IndustryBiotechnologyBiotechnology
Market Capitalization28.08 billion USD138.71 billion USD
CurrencyUSDUSD
ExchangeNasdaqNasdaq
Listing DateDecember 8, 2020July 24, 1991
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

ROIV
VRTX
GSPC
Loading price history…
Roivant Sciences (ROIV) vs. Vertex Pharmaceuticals (VRTX), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

Loading price history…
Trailing total returns for Roivant Sciences (ROIV) and Vertex Pharmaceuticals (VRTX). Returns over one year are annualized.

Calendar-Year Returns

Loading price history…
Calendar-year total returns for Roivant Sciences (ROIV) and Vertex Pharmaceuticals (VRTX). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Roivant Sciences (ROIV) and Vertex Pharmaceuticals (VRTX)
MetricROIVVRTX
Total Return (1Y)96.75%34.89%
Total Return (3Y, Annualized)68.04%14.44%
Total Return (5Y, Annualized)36.73%23.65%

Risk Profile

Drawdown History

ROIV
VRTX
GSPC
Loading price history…
Roivant Sciences (ROIV) vs. Vertex Pharmaceuticals (VRTX), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

Loading price history…
Distribution of monthly total returns for Roivant Sciences (ROIV) and Vertex Pharmaceuticals (VRTX). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Roivant Sciences (ROIV) and Vertex Pharmaceuticals (VRTX)
MetricROIVVRTX
Volatility (1Y, Annualized)47.99%29.73%
Beta (5Y)1.170.29
Max Drawdown (5Y)-79.22%-29.07%
Avg. Volume (3M)7.82M1.25M

Risk-Adjusted Performance

Risk-Return Positioning

Loading chart…
ROIV and VRTX are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Roivant Sciences (ROIV) and Vertex Pharmaceuticals (VRTX)
MetricROIVVRTX
Sharpe Ratio (1Y)1.931.03
Sortino Ratio (1Y)4.031.68

Profitability

ROE (TTM)

Roivant Sciences (ROIV) reports a negative ROE of -8.52%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile Vertex Pharmaceuticals (VRTX) reports 20.80%, ranking against industry peers normally.

ROIV

Pharmaceuticals, Biotechnology & Life Sciences industry group

-8.52%

Max
109.18%
Q3
6.23%
ROIV
-8.52%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

20.80%

Max
109.18%
VRTX
20.80%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
Loading chart…
Roivant Sciences (ROIV) vs. Vertex Pharmaceuticals (VRTX): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Vertex Pharmaceuticals (VRTX) at 30.70% converts revenue to bottom-line profit above its industry’s benchmark range, while Roivant Sciences (ROIV) at 0.00% keeps roughly the typical share for its industry.

ROIV

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

Max
18.05%
Q3
4.78%
ROIV
0.00%
Median
0.00%
Q1
-4.14%
Min
-17.05%

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

30.70%

VRTX
30.70%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
Loading chart…
Roivant Sciences (ROIV) vs. Vertex Pharmaceuticals (VRTX): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Roivant Sciences (ROIV) reports a negative operating margin of -25,408.11%, usually indicating that operating costs exceeded revenue at the operating-income line. Meanwhile Vertex Pharmaceuticals (VRTX) reports 35.57%, ranking against industry peers normally.

ROIV

Pharmaceuticals, Biotechnology & Life Sciences industry group

-25,408.11%

Max
83.12%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
ROIV
-25,408.11%

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

35.57%

Max
83.12%
VRTX
35.57%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
Loading chart…
Roivant Sciences (ROIV) vs. Vertex Pharmaceuticals (VRTX): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Roivant Sciences (ROIV) and Vertex Pharmaceuticals (VRTX)
MetricROIVVRTX
ROE (TTM)-8.52%20.80%
ROA (TTM)-16.28%10.62%
Net Margin (TTM)0.00%30.70%
Operating Margin (TTM)-25,408.11%35.57%
Gross Margin (TTM)0.00%54.81%

Growth

Revenue Growth

Vertex Pharmaceuticals (VRTX) at 8.90% is around its peer norm for revenue growth, while Roivant Sciences (ROIV) at -71.57% drops into the bottom quartile, signaling weaker demand or pricing momentum.

Loading chart…
Roivant Sciences (ROIV) vs. Vertex Pharmaceuticals (VRTX): A comparison of their Revenue Growth across different time periods.

EPS Growth

Neither Roivant Sciences (ROIV) nor Vertex Pharmaceuticals (VRTX) reports a EPS growth value for this period, so a direct comparison isn't possible.

Loading chart…
Roivant Sciences (ROIV) vs. Vertex Pharmaceuticals (VRTX): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Roivant Sciences (ROIV) and Vertex Pharmaceuticals (VRTX)
MetricROIVVRTX
Revenue Growth (YoY)-71.57%8.90%
Revenue Growth (3Y CAGR)-36.01%10.35%
EPS Growth (YoY)----
EPS Growth (3Y CAGR)--6.12%

Financial Strength

Current Ratio (MRQ)

Roivant Sciences (ROIV) at 16.72 carries current ratio above its industry’s typical mid-range, while Vertex Pharmaceuticals (VRTX) at 2.34 runs in the tighter-liquidity quartile — different working-capital profiles, both worth examining.

ROIV

Pharmaceuticals, Biotechnology & Life Sciences industry group

16.72

Max
25.13
ROIV
16.72
Q3
12.13
Median
5.52
Q1
2.47
Min
0.10

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.34

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
VRTX
2.34
Min
0.10
Loading chart…
Roivant Sciences (ROIV) vs. Vertex Pharmaceuticals (VRTX): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Both Roivant Sciences (ROIV) at 0.02 and Vertex Pharmaceuticals (VRTX) at 0.31 fund their balance sheets with roughly industry-typical debt-to-equity mixes.

ROIV

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.02

Max
1.42
Q3
0.65
Median
0.15
ROIV
0.02
Q1
0.02
Min
0.00

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.31

Max
1.42
Q3
0.65
VRTX
0.31
Median
0.15
Q1
0.02
Min
0.00
Loading chart…
Roivant Sciences (ROIV) vs. Vertex Pharmaceuticals (VRTX): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Roivant Sciences (ROIV) and Vertex Pharmaceuticals (VRTX)
MetricROIVVRTX
Current Ratio (MRQ)16.722.34
Debt / Equity (MRQ)0.020.31
Net Debt / EBITDA--0.03

Dividends

Dividend Yield (TTM)

Neither Roivant Sciences (ROIV) nor Vertex Pharmaceuticals (VRTX) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

ROIV

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ROIV
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

VRTX
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
Loading chart…
Roivant Sciences (ROIV) vs. Vertex Pharmaceuticals (VRTX): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Neither Roivant Sciences (ROIV) nor Vertex Pharmaceuticals (VRTX) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

ROIV

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ROIV
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

VRTX
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
Loading chart…
Roivant Sciences (ROIV) vs. Vertex Pharmaceuticals (VRTX): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Roivant Sciences (ROIV) and Vertex Pharmaceuticals (VRTX)
MetricROIVVRTX
Dividend Yield (TTM)0.00%0.00%
Dividend Payout Ratio (TTM)0.00%0.00%

Valuation

P/E Ratio (TTM)

An earnings multiple is available for just one side: Vertex Pharmaceuticals (VRTX) trades at 35.21 times trailing earnings, ranked against its peers, while Roivant Sciences (ROIV) has no P/E ratio this period.

ROIV

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
ROIV
--

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

35.21

Max
85.34
Q3
43.46
VRTX
35.21
Median
26.69
Q1
13.30
Min
0.07
Loading chart…
Roivant Sciences (ROIV) vs. Vertex Pharmaceuticals (VRTX): ROIV does not report P/E ratio, so it has no value marker; VRTX is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

P/S Ratio (TTM)

Vertex Pharmaceuticals (VRTX) at 10.71 prices around its industry’s typical P/S ratio, while Roivant Sciences (ROIV) at 3,728.61 clears its benchmark range — ROIV looks notably rich on sales.

ROIV

Pharmaceuticals, Biotechnology & Life Sciences industry group

3,728.61

ROIV
3,728.61
Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
Min
0.01

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

10.71

Max
58.18
Q3
25.77
VRTX
10.71
Median
7.30
Q1
3.01
Min
0.01
Loading chart…
Roivant Sciences (ROIV) vs. Vertex Pharmaceuticals (VRTX): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Both Roivant Sciences (ROIV) at 6.64 and Vertex Pharmaceuticals (VRTX) at 6.63 carry a premium to book value versus peers, sitting in the upper P/B ratio quartile of their industries.

ROIV

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.64

Max
13.53
ROIV
6.64
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.63

Max
13.53
VRTX
6.63
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
Loading chart…
Roivant Sciences (ROIV) vs. Vertex Pharmaceuticals (VRTX): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Roivant Sciences (ROIV) and Vertex Pharmaceuticals (VRTX)
MetricROIVVRTX
P/E Ratio (TTM)--35.21
P/S Ratio (TTM)3,728.6110.71
P/B Ratio (MRQ)6.646.63
Free Cash Flow Yield (TTM)-3.98%1.69%