PCVX vs. RPRX: Vaxcyte vs. Royalty Pharma Stock Comparison
How do Vaxcyte (PCVX) and Royalty Pharma (RPRX) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.
Company Profile
Vaxcyte (PCVX) and Royalty Pharma (RPRX) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but PCVX is classified in Biotechnology while RPRX is classified in Pharmaceuticals.
| Profile Item | PCVX | RPRX |
|---|---|---|
| Name | Vaxcyte Inc. | Royalty Pharma plc Class A Ordinary Shares |
| Country/Region | United States | United States |
| GICS Sector | Health Care | Health Care |
| GICS Industry Group | Pharmaceuticals, Biotechnology & Life Sciences | Pharmaceuticals, Biotechnology & Life Sciences |
| GICS Industry | Biotechnology | Pharmaceuticals |
| GICS Sub-Industry | Biotechnology | Pharmaceuticals |
| Market Capitalization | 10.11 billion USD | 38.70 billion USD |
| Currency | USD | USD |
| Exchange | Nasdaq | Nasdaq |
| Listing Date | June 12, 2020 | June 16, 2020 |
| Security Type | Common Stock | Common Stock |
Price Performance
Cumulative Growth
Trailing Returns
Calendar-Year Returns
Performance Metrics
| Metric | PCVX | RPRX |
|---|---|---|
| Total Return (1Y) | 59.00% | 81.08% |
| Total Return (3Y, Annualized) | 11.29% | 39.21% |
| Total Return (5Y, Annualized) | 21.60% | 14.22% |
Risk Profile
Drawdown History
Return Distribution
Risk Metrics
| Metric | PCVX | RPRX |
|---|---|---|
| Volatility (1Y, Annualized) | 56.01% | 22.05% |
| Beta (5Y) | 1.26 | 0.36 |
| Max Drawdown (5Y) | -76.22% | -41.98% |
| Avg. Volume (3M) | 2.12M | 3.10M |
Risk-Adjusted Performance
Risk-Return Positioning
Risk-Adjusted Metrics
| Metric | PCVX | RPRX |
|---|---|---|
| Sharpe Ratio (1Y) | 0.98 | 3.48 |
| Sortino Ratio (1Y) | 1.76 | 5.72 |
Profitability
ROE (TTM)
Vaxcyte (PCVX) reports a negative ROE of -42.68%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile Royalty Pharma (RPRX) reports 12.09%, ranking against industry peers normally.
PCVX
Pharmaceuticals, Biotechnology & Life Sciences industry group
-42.68%
- Max
- 109.18%
- Q3
- 6.23%
- Median
- -26.66%
- PCVX
- -42.68%
- Q1
- -64.05%
- Min
- -167.77%
RPRX
Pharmaceuticals, Biotechnology & Life Sciences industry group
12.09%
- Max
- 109.18%
- RPRX
- 12.09%
- Q3
- 6.23%
- Median
- -26.66%
- Q1
- -64.05%
- Min
- -167.77%
Net Margin (TTM)
Royalty Pharma (RPRX) at 25.70% converts revenue to bottom-line profit above its industry’s benchmark range, while Vaxcyte (PCVX) at 0.00% keeps roughly the typical share for its industry.
PCVX
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.00%
- Max
- 18.05%
- Q3
- 4.78%
- PCVX
- 0.00%
- Median
- 0.00%
- Q1
- -4.14%
- Min
- -17.05%
RPRX
Pharmaceuticals, Biotechnology & Life Sciences industry group
25.70%
- RPRX
- 25.70%
- Max
- 18.05%
- Q3
- 4.78%
- Median
- 0.00%
- Q1
- -4.14%
- Min
- -17.05%
Operating Margin (TTM)
Royalty Pharma (RPRX) at 81.32% operates in the top operating margin quartile, ahead of Vaxcyte (PCVX) at 0.00%, which runs around its industry’s norm.
PCVX
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.00%
- Max
- 83.12%
- Q3
- 14.77%
- PCVX
- 0.00%
- Median
- 0.00%
- Q1
- -78.82%
- Min
- -207.40%
RPRX
Pharmaceuticals, Biotechnology & Life Sciences industry group
81.32%
- Max
- 83.12%
- RPRX
- 81.32%
- Q3
- 14.77%
- Median
- 0.00%
- Q1
- -78.82%
- Min
- -207.40%
Profitability Metrics
| Metric | PCVX | RPRX |
|---|---|---|
| ROE (TTM) | -42.68% | 12.09% |
| ROA (TTM) | -24.98% | 5.43% |
| Net Margin (TTM) | 0.00% | 25.70% |
| Operating Margin (TTM) | 0.00% | 81.32% |
| Gross Margin (TTM) | 0.00% | 99.79% |
Growth
Revenue Growth
Only one side can be read here: Royalty Pharma (RPRX) reports revenue growth of 5.06%, ranked against its industry; Vaxcyte (PCVX) has no revenue growth figure this period.
EPS Growth
Only one side can be read here: Royalty Pharma (RPRX) reports EPS growth of 23.09%, ranked against its industry; Vaxcyte (PCVX) has no EPS growth figure this period.
Growth Metrics
| Metric | PCVX | RPRX |
|---|---|---|
| Revenue Growth (YoY) | -- | 5.06% |
| Revenue Growth (3Y CAGR) | -- | 2.06% |
| EPS Growth (YoY) | -- | 23.09% |
| EPS Growth (3Y CAGR) | -- | 161.10% |
Financial Strength
Current Ratio (MRQ)
Vaxcyte (PCVX) at 4.56 keeps current ratio within its industry’s typical mid-range, while Royalty Pharma (RPRX) at 1.29 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for RPRX.
PCVX
Pharmaceuticals, Biotechnology & Life Sciences industry group
4.56
- Max
- 25.13
- Q3
- 12.13
- Median
- 5.52
- PCVX
- 4.56
- Q1
- 2.47
- Min
- 0.10
RPRX
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.29
- Max
- 25.13
- Q3
- 12.13
- Median
- 5.52
- Q1
- 2.47
- RPRX
- 1.29
- Min
- 0.10
Debt / Equity (MRQ)
Vaxcyte (PCVX) at 0.09 carries an industry-typical debt-to-equity mix, while Royalty Pharma (RPRX) at 0.88 uses more debt funding than most peers.
PCVX
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.09
- Max
- 1.42
- Q3
- 0.65
- Median
- 0.15
- PCVX
- 0.09
- Q1
- 0.02
- Min
- 0.00
RPRX
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.88
- Max
- 1.42
- RPRX
- 0.88
- Q3
- 0.65
- Median
- 0.15
- Q1
- 0.02
- Min
- 0.00
Financial Strength Metrics
| Metric | PCVX | RPRX |
|---|---|---|
| Current Ratio (MRQ) | 4.56 | 1.29 |
| Debt / Equity (MRQ) | 0.09 | 0.88 |
| Net Debt / EBITDA | -- | 4.76 |
Dividends
Dividend Yield (TTM)
Vaxcyte (PCVX) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Royalty Pharma (RPRX) reports a yield of 1.37%, ranking against industry peers normally.
PCVX
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.00%
- PCVX
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
RPRX
Pharmaceuticals, Biotechnology & Life Sciences industry group
1.37%
- RPRX
- 1.37%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Payout Ratio (TTM)
Vaxcyte (PCVX) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Royalty Pharma (RPRX) reports a payout of 60.46%, ranking against industry peers normally.
PCVX
Pharmaceuticals, Biotechnology & Life Sciences industry group
0.00%
- PCVX
- 0.00%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
RPRX
Pharmaceuticals, Biotechnology & Life Sciences industry group
60.46%
- RPRX
- 60.46%
- Max
- 0.00%
- Q3
- 0.00%
- Median
- 0.00%
- Q1
- 0.00%
- Min
- 0.00%
Dividend Metrics
| Metric | PCVX | RPRX |
|---|---|---|
| Dividend Yield (TTM) | 0.00% | 1.37% |
| Dividend Payout Ratio (TTM) | 0.00% | 60.46% |
Valuation
P/E Ratio (TTM)
An earnings multiple is available for just one side: Royalty Pharma (RPRX) trades at 43.99 times trailing earnings, ranked against its peers, while Vaxcyte (PCVX) has no P/E ratio this period.
PCVX
Pharmaceuticals, Biotechnology & Life Sciences industry group
--
- Max
- 85.34
- Q3
- 43.46
- Median
- 26.69
- Q1
- 13.30
- Min
- 0.07
- PCVX
- --
RPRX
Pharmaceuticals, Biotechnology & Life Sciences industry group
43.99
- Max
- 85.34
- RPRX
- 43.99
- Q3
- 43.46
- Median
- 26.69
- Q1
- 13.30
- Min
- 0.07
P/S Ratio (TTM)
A sales-based read is only available for Royalty Pharma (RPRX), whose P/S ratio of 14.79 ranks against industry peers; Vaxcyte (PCVX) reports no figure this period.
PCVX
Pharmaceuticals, Biotechnology & Life Sciences industry group
--
- Max
- 58.18
- Q3
- 25.77
- Median
- 7.30
- Q1
- 3.01
- Min
- 0.01
- PCVX
- --
RPRX
Pharmaceuticals, Biotechnology & Life Sciences industry group
14.79
- Max
- 58.18
- Q3
- 25.77
- RPRX
- 14.79
- Median
- 7.30
- Q1
- 3.01
- Min
- 0.01
P/B Ratio (MRQ)
On P/B ratio, both Vaxcyte (PCVX) at 3.83 and Royalty Pharma (RPRX) at 4.39 are valued close to their industries’ norm against book — neither stands out from peers.
PCVX
Pharmaceuticals, Biotechnology & Life Sciences industry group
3.83
- Max
- 13.53
- Q3
- 6.54
- PCVX
- 3.83
- Median
- 3.25
- Q1
- 1.69
- Min
- -5.59
RPRX
Pharmaceuticals, Biotechnology & Life Sciences industry group
4.39
- Max
- 13.53
- Q3
- 6.54
- RPRX
- 4.39
- Median
- 3.25
- Q1
- 1.69
- Min
- -5.59
Valuation Metrics
| Metric | PCVX | RPRX |
|---|---|---|
| P/E Ratio (TTM) | -- | 43.99 |
| P/S Ratio (TTM) | -- | 14.79 |
| P/B Ratio (MRQ) | 3.83 | 4.39 |
| Free Cash Flow Yield (TTM) | -5.24% | -1.16% |