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ONC vs. RPRX: BeOne Medicines vs. Royalty Pharma Stock Comparison

How do BeOne Medicines (ONC) and Royalty Pharma (RPRX) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

BeOne Medicines (ONC) and Royalty Pharma (RPRX) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but ONC is classified in Biotechnology while RPRX is classified in Pharmaceuticals.

Royalty Pharma (RPRX) trades as ordinary local shares, while BeOne Medicines (ONC) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.

Company profile comparison for BeOne Medicines (ONC) and Royalty Pharma (RPRX)
Profile ItemONCRPRX
NameBeOne Medicines Ltd. American Depositary SharesRoyalty Pharma plc Class A Ordinary Shares
Country/RegionSwitzerlandUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyPharmaceuticals
GICS Sub-IndustryBiotechnologyPharmaceuticals
Market Capitalization46.49 billion USD38.70 billion USD
CurrencyUSDUSD
ExchangeNasdaqNasdaq
Listing DateFebruary 3, 2016June 16, 2020
Security TypeADRCommon Stock

Price Performance

Cumulative Growth

ONC
RPRX
GSPC
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BeOne Medicines (ONC) vs. Royalty Pharma (RPRX), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for BeOne Medicines (ONC) and Royalty Pharma (RPRX). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for BeOne Medicines (ONC) and Royalty Pharma (RPRX). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for BeOne Medicines (ONC) and Royalty Pharma (RPRX)
MetricONCRPRX
Total Return (1Y)30.59%81.08%
Total Return (3Y, Annualized)30.15%39.21%
Total Return (5Y, Annualized)2.48%14.22%

Risk Profile

Drawdown History

ONC
RPRX
GSPC
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BeOne Medicines (ONC) vs. Royalty Pharma (RPRX), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for BeOne Medicines (ONC) and Royalty Pharma (RPRX). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for BeOne Medicines (ONC) and Royalty Pharma (RPRX)
MetricONCRPRX
Volatility (1Y, Annualized)35.90%22.05%
Beta (5Y)0.590.36
Max Drawdown (5Y)-68.89%-41.98%
Avg. Volume (3M)405.29K3.10M

Risk-Adjusted Performance

Risk-Return Positioning

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ONC and RPRX are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for BeOne Medicines (ONC) and Royalty Pharma (RPRX)
MetricONCRPRX
Sharpe Ratio (1Y)0.733.48
Sortino Ratio (1Y)1.155.72

Profitability

ROE (TTM)

Both BeOne Medicines (ONC) at 18.40% and Royalty Pharma (RPRX) at 12.09% sit in the top peer quartile for ROE, suggesting each generates more profit from shareholders’ equity than typical industry peers.

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

18.40%

Max
109.18%
ONC
18.40%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

12.09%

Max
109.18%
RPRX
12.09%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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BeOne Medicines (ONC) vs. Royalty Pharma (RPRX): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Royalty Pharma (RPRX) at 25.70% keeps the most of each sales dollar — above its industry’s net margin range — and BeOne Medicines (ONC) at 13.86% also retains a top-quartile share.

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

13.86%

Max
18.05%
ONC
13.86%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

25.70%

RPRX
25.70%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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BeOne Medicines (ONC) vs. Royalty Pharma (RPRX): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both BeOne Medicines (ONC) at 22.15% and Royalty Pharma (RPRX) at 81.32% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

22.15%

Max
83.12%
ONC
22.15%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

81.32%

Max
83.12%
RPRX
81.32%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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BeOne Medicines (ONC) vs. Royalty Pharma (RPRX): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for BeOne Medicines (ONC) and Royalty Pharma (RPRX)
MetricONCRPRX
ROE (TTM)18.40%12.09%
ROA (TTM)8.42%5.43%
Net Margin (TTM)13.86%25.70%
Operating Margin (TTM)22.15%81.32%
Gross Margin (TTM)89.39%99.79%

Growth

Revenue Growth

Both BeOne Medicines (ONC) at 40.23% and Royalty Pharma (RPRX) at 5.06% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

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BeOne Medicines (ONC) vs. Royalty Pharma (RPRX): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: Royalty Pharma (RPRX) reports EPS growth of 23.09%, ranked against its industry; BeOne Medicines (ONC) has no EPS growth figure this period.

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BeOne Medicines (ONC) vs. Royalty Pharma (RPRX): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for BeOne Medicines (ONC) and Royalty Pharma (RPRX)
MetricONCRPRX
Revenue Growth (YoY)40.23%5.06%
Revenue Growth (3Y CAGR)55.69%2.06%
EPS Growth (YoY)--23.09%
EPS Growth (3Y CAGR)--161.10%

Financial Strength

Current Ratio (MRQ)

BeOne Medicines (ONC) at 3.55 keeps current ratio within its industry’s typical mid-range, while Royalty Pharma (RPRX) at 1.29 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for RPRX.

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.55

Max
25.13
Q3
12.13
Median
5.52
ONC
3.55
Q1
2.47
Min
0.10

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.29

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
RPRX
1.29
Min
0.10
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BeOne Medicines (ONC) vs. Royalty Pharma (RPRX): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

BeOne Medicines (ONC) at 0.35 carries an industry-typical debt-to-equity mix, while Royalty Pharma (RPRX) at 0.88 uses more debt funding than most peers.

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.35

Max
1.42
Q3
0.65
ONC
0.35
Median
0.15
Q1
0.02
Min
0.00

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.88

Max
1.42
RPRX
0.88
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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BeOne Medicines (ONC) vs. Royalty Pharma (RPRX): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for BeOne Medicines (ONC) and Royalty Pharma (RPRX)
MetricONCRPRX
Current Ratio (MRQ)3.551.29
Debt / Equity (MRQ)0.350.88
Net Debt / EBITDA-2.804.76

Dividends

Dividend Yield (TTM)

BeOne Medicines (ONC) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Royalty Pharma (RPRX) reports a yield of 1.37%, ranking against industry peers normally.

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ONC
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.37%

RPRX
1.37%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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BeOne Medicines (ONC) vs. Royalty Pharma (RPRX): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

BeOne Medicines (ONC) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Royalty Pharma (RPRX) reports a payout of 60.46%, ranking against industry peers normally.

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ONC
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

60.46%

RPRX
60.46%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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BeOne Medicines (ONC) vs. Royalty Pharma (RPRX): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for BeOne Medicines (ONC) and Royalty Pharma (RPRX)
MetricONCRPRX
Dividend Yield (TTM)0.00%1.37%
Dividend Payout Ratio (TTM)0.00%60.46%

Valuation

P/E Ratio (TTM)

Both BeOne Medicines (ONC) at 52.17 and Royalty Pharma (RPRX) at 43.99 sit in the richer earnings-multiple quartile for P/E ratio, so investors are paying more for TTM earnings than they pay for typical peers.

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

52.17

Max
85.34
ONC
52.17
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

43.99

Max
85.34
RPRX
43.99
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
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BeOne Medicines (ONC) vs. Royalty Pharma (RPRX): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

On P/S ratio, both BeOne Medicines (ONC) at 7.04 and Royalty Pharma (RPRX) at 14.79 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

7.04

Max
58.18
Q3
25.77
Median
7.30
ONC
7.04
Q1
3.01
Min
0.01

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

14.79

Max
58.18
Q3
25.77
RPRX
14.79
Median
7.30
Q1
3.01
Min
0.01
Loading chart…
BeOne Medicines (ONC) vs. Royalty Pharma (RPRX): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Royalty Pharma (RPRX) at 4.39 is valued about in line with its industry on P/B ratio, while BeOne Medicines (ONC) at 7.98 carries an above-peer premium to book — ONC is pricier on assets.

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

7.98

Max
13.53
ONC
7.98
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.39

Max
13.53
Q3
6.54
RPRX
4.39
Median
3.25
Q1
1.69
Min
-5.59
Loading chart…
BeOne Medicines (ONC) vs. Royalty Pharma (RPRX): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for BeOne Medicines (ONC) and Royalty Pharma (RPRX)
MetricONCRPRX
P/E Ratio (TTM)52.1743.99
P/S Ratio (TTM)7.0414.79
P/B Ratio (MRQ)7.984.39
Free Cash Flow Yield (TTM)2.21%-1.16%