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ONC vs. QGEN: BeOne Medicines vs. Qiagen Stock Comparison

How do BeOne Medicines (ONC) and Qiagen (QGEN) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

BeOne Medicines (ONC) and Qiagen (QGEN) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but ONC is classified in Biotechnology while QGEN is classified in Life Sciences Tools & Services.

Qiagen (QGEN) trades as ordinary local shares, while BeOne Medicines (ONC) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.

Company profile comparison for BeOne Medicines (ONC) and Qiagen (QGEN)
Profile ItemONCQGEN
NameBeOne Medicines Ltd. American Depositary SharesQiagen N.V.
Country/RegionSwitzerlandNetherlands
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyLife Sciences Tools & Services
GICS Sub-IndustryBiotechnologyLife Sciences Tools & Services
Market Capitalization46.49 billion USD10.39 billion USD
CurrencyUSDUSD
ExchangeNasdaqNYSE
Listing DateFebruary 3, 2016June 28, 1996
Security TypeADRCommon Stock

Price Performance

Cumulative Growth

ONC
QGEN
GSPC
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BeOne Medicines (ONC) vs. Qiagen (QGEN), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for BeOne Medicines (ONC) and Qiagen (QGEN). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for BeOne Medicines (ONC) and Qiagen (QGEN). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for BeOne Medicines (ONC) and Qiagen (QGEN)
MetricONCQGEN
Total Return (1Y)30.59%17.09%
Total Return (3Y, Annualized)30.15%10.44%
Total Return (5Y, Annualized)2.48%-0.72%

Risk Profile

Drawdown History

ONC
QGEN
GSPC
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BeOne Medicines (ONC) vs. Qiagen (QGEN), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for BeOne Medicines (ONC) and Qiagen (QGEN). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for BeOne Medicines (ONC) and Qiagen (QGEN)
MetricONCQGEN
Volatility (1Y, Annualized)35.90%35.52%
Beta (5Y)0.590.56
Max Drawdown (5Y)-68.89%-41.97%
Avg. Volume (3M)405.29K3.68M

Risk-Adjusted Performance

Risk-Return Positioning

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ONC and QGEN are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for BeOne Medicines (ONC) and Qiagen (QGEN)
MetricONCQGEN
Sharpe Ratio (1Y)0.730.36
Sortino Ratio (1Y)1.150.60

Profitability

ROE (TTM)

Both BeOne Medicines (ONC) at 18.40% and Qiagen (QGEN) at 10.81% sit in the top peer quartile for ROE, suggesting each generates more profit from shareholders’ equity than typical industry peers.

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

18.40%

Max
109.18%
ONC
18.40%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

QGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

10.81%

Max
109.18%
QGEN
10.81%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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BeOne Medicines (ONC) vs. Qiagen (QGEN): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Qiagen (QGEN) at 18.20% keeps the most of each sales dollar — above its industry’s net margin range — and BeOne Medicines (ONC) at 13.86% also retains a top-quartile share.

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

13.86%

Max
18.05%
ONC
13.86%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

QGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

18.20%

QGEN
18.20%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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BeOne Medicines (ONC) vs. Qiagen (QGEN): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both BeOne Medicines (ONC) at 22.15% and Qiagen (QGEN) at 27.75% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

22.15%

Max
83.12%
ONC
22.15%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

QGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

27.75%

Max
83.12%
QGEN
27.75%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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BeOne Medicines (ONC) vs. Qiagen (QGEN): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for BeOne Medicines (ONC) and Qiagen (QGEN)
MetricONCQGEN
ROE (TTM)18.40%10.81%
ROA (TTM)8.42%5.68%
Net Margin (TTM)13.86%18.20%
Operating Margin (TTM)22.15%27.75%
Gross Margin (TTM)89.39%67.06%

Growth

Revenue Growth

Both BeOne Medicines (ONC) at 40.23% and Qiagen (QGEN) at 5.65% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

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BeOne Medicines (ONC) vs. Qiagen (QGEN): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: Qiagen (QGEN) reports EPS growth of 409.76%, ranked against its industry; BeOne Medicines (ONC) has no EPS growth figure this period.

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BeOne Medicines (ONC) vs. Qiagen (QGEN): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for BeOne Medicines (ONC) and Qiagen (QGEN)
MetricONCQGEN
Revenue Growth (YoY)40.23%5.65%
Revenue Growth (3Y CAGR)55.69%-0.81%
EPS Growth (YoY)--409.76%
EPS Growth (3Y CAGR)---0.19%

Financial Strength

Current Ratio (MRQ)

Both BeOne Medicines (ONC) at 3.55 and Qiagen (QGEN) at 2.63 carry current ratio within their industries’ typical mid-ranges, suggesting balanced short-term liquidity relative to peers.

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.55

Max
25.13
Q3
12.13
Median
5.52
ONC
3.55
Q1
2.47
Min
0.10

QGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.63

Max
25.13
Q3
12.13
Median
5.52
QGEN
2.63
Q1
2.47
Min
0.10
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BeOne Medicines (ONC) vs. Qiagen (QGEN): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Both BeOne Medicines (ONC) at 0.35 and Qiagen (QGEN) at 0.47 fund their balance sheets with roughly industry-typical debt-to-equity mixes.

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.35

Max
1.42
Q3
0.65
ONC
0.35
Median
0.15
Q1
0.02
Min
0.00

QGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.47

Max
1.42
Q3
0.65
QGEN
0.47
Median
0.15
Q1
0.02
Min
0.00
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BeOne Medicines (ONC) vs. Qiagen (QGEN): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for BeOne Medicines (ONC) and Qiagen (QGEN)
MetricONCQGEN
Current Ratio (MRQ)3.552.63
Debt / Equity (MRQ)0.350.47
Net Debt / EBITDA-2.801.08

Dividends

Dividend Yield (TTM)

BeOne Medicines (ONC) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Qiagen (QGEN) reports a yield of 0.71%, ranking against industry peers normally.

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ONC
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

QGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.71%

QGEN
0.71%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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BeOne Medicines (ONC) vs. Qiagen (QGEN): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

BeOne Medicines (ONC) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Qiagen (QGEN) reports a payout of 18.21%, ranking against industry peers normally.

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ONC
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

QGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

18.21%

QGEN
18.21%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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BeOne Medicines (ONC) vs. Qiagen (QGEN): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for BeOne Medicines (ONC) and Qiagen (QGEN)
MetricONCQGEN
Dividend Yield (TTM)0.00%0.71%
Dividend Payout Ratio (TTM)0.00%18.21%

Valuation

P/E Ratio (TTM)

Qiagen (QGEN) at 27.21 is near its industry’s usual P/E ratio, while BeOne Medicines (ONC) at 52.17 sits in the richer quartile — ONC needs stronger growth or earnings quality to justify the premium.

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

52.17

Max
85.34
ONC
52.17
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07

QGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

27.21

Max
85.34
Q3
43.46
QGEN
27.21
Median
26.69
Q1
13.30
Min
0.07
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BeOne Medicines (ONC) vs. Qiagen (QGEN): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

On P/S ratio, both BeOne Medicines (ONC) at 7.04 and Qiagen (QGEN) at 4.91 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

7.04

Max
58.18
Q3
25.77
Median
7.30
ONC
7.04
Q1
3.01
Min
0.01

QGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.91

Max
58.18
Q3
25.77
Median
7.30
QGEN
4.91
Q1
3.01
Min
0.01
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BeOne Medicines (ONC) vs. Qiagen (QGEN): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Qiagen (QGEN) at 2.99 is valued about in line with its industry on P/B ratio, while BeOne Medicines (ONC) at 7.98 carries an above-peer premium to book — ONC is pricier on assets.

ONC

Pharmaceuticals, Biotechnology & Life Sciences industry group

7.98

Max
13.53
ONC
7.98
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

QGEN

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.99

Max
13.53
Q3
6.54
Median
3.25
QGEN
2.99
Q1
1.69
Min
-5.59
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BeOne Medicines (ONC) vs. Qiagen (QGEN): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for BeOne Medicines (ONC) and Qiagen (QGEN)
MetricONCQGEN
P/E Ratio (TTM)52.1727.21
P/S Ratio (TTM)7.044.91
P/B Ratio (MRQ)7.982.99
Free Cash Flow Yield (TTM)2.21%3.62%