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NBIX vs. RPRX: Neurocrine Biosciences vs. Royalty Pharma Stock Comparison

How do Neurocrine Biosciences (NBIX) and Royalty Pharma (RPRX) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Neurocrine Biosciences (NBIX) and Royalty Pharma (RPRX) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but NBIX is classified in Biotechnology while RPRX is classified in Pharmaceuticals.

Neurocrine Biosciences (NBIX) has more than two decades of public-market history since May 23, 1996, whereas Royalty Pharma (RPRX) listed on June 16, 2020 and has a much shorter record to draw on.

Company profile comparison for Neurocrine Biosciences (NBIX) and Royalty Pharma (RPRX)
Profile ItemNBIXRPRX
NameNeurocrine Biosciences, Inc.Royalty Pharma plc Class A Ordinary Shares
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyPharmaceuticals
GICS Sub-IndustryBiotechnologyPharmaceuticals
Market Capitalization16.66 billion USD38.70 billion USD
CurrencyUSDUSD
ExchangeNasdaqNasdaq
Listing DateMay 23, 1996June 16, 2020
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

NBIX
RPRX
GSPC
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Neurocrine Biosciences (NBIX) vs. Royalty Pharma (RPRX), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Neurocrine Biosciences (NBIX) and Royalty Pharma (RPRX). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Neurocrine Biosciences (NBIX) and Royalty Pharma (RPRX). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Neurocrine Biosciences (NBIX) and Royalty Pharma (RPRX)
MetricNBIXRPRX
Total Return (1Y)9.40%81.08%
Total Return (3Y, Annualized)14.12%39.21%
Total Return (5Y, Annualized)12.61%14.22%

Risk Profile

Drawdown History

NBIX
RPRX
GSPC
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Neurocrine Biosciences (NBIX) vs. Royalty Pharma (RPRX), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Neurocrine Biosciences (NBIX) and Royalty Pharma (RPRX). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Neurocrine Biosciences (NBIX) and Royalty Pharma (RPRX)
MetricNBIXRPRX
Volatility (1Y, Annualized)35.05%22.05%
Beta (5Y)0.290.36
Max Drawdown (5Y)-42.89%-41.98%
Avg. Volume (3M)1.31M3.10M

Risk-Adjusted Performance

Risk-Return Positioning

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NBIX and RPRX are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Neurocrine Biosciences (NBIX) and Royalty Pharma (RPRX)
MetricNBIXRPRX
Sharpe Ratio (1Y)0.153.48
Sortino Ratio (1Y)0.225.72

Profitability

ROE (TTM)

Both Neurocrine Biosciences (NBIX) at 20.42% and Royalty Pharma (RPRX) at 12.09% sit in the top peer quartile for ROE, suggesting each generates more profit from shareholders’ equity than typical industry peers.

NBIX

Pharmaceuticals, Biotechnology & Life Sciences industry group

20.42%

Max
109.18%
NBIX
20.42%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

12.09%

Max
109.18%
RPRX
12.09%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Neurocrine Biosciences (NBIX) vs. Royalty Pharma (RPRX): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Both Neurocrine Biosciences (NBIX) at 18.98% and Royalty Pharma (RPRX) at 25.70% keep an unusually large share of revenue as bottom-line profit — each net margin clears its industry’s benchmark range.

NBIX

Pharmaceuticals, Biotechnology & Life Sciences industry group

18.98%

NBIX
18.98%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

25.70%

RPRX
25.70%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Neurocrine Biosciences (NBIX) vs. Royalty Pharma (RPRX): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Neurocrine Biosciences (NBIX) at 31.98% and Royalty Pharma (RPRX) at 81.32% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

NBIX

Pharmaceuticals, Biotechnology & Life Sciences industry group

31.98%

Max
83.12%
NBIX
31.98%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

81.32%

Max
83.12%
RPRX
81.32%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Neurocrine Biosciences (NBIX) vs. Royalty Pharma (RPRX): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Neurocrine Biosciences (NBIX) and Royalty Pharma (RPRX)
MetricNBIXRPRX
ROE (TTM)20.42%12.09%
ROA (TTM)12.45%5.43%
Net Margin (TTM)18.98%25.70%
Operating Margin (TTM)31.98%81.32%
Gross Margin (TTM)64.67%99.79%

Growth

Revenue Growth

Both Neurocrine Biosciences (NBIX) at 21.45% and Royalty Pharma (RPRX) at 5.06% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

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Neurocrine Biosciences (NBIX) vs. Royalty Pharma (RPRX): A comparison of their Revenue Growth across different time periods.

EPS Growth

Both Neurocrine Biosciences (NBIX) at 41.95% and Royalty Pharma (RPRX) at 23.09% land near their industries' usual EPS growth ranges, so bottom-line momentum looks broadly in line with peers on both sides.

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Neurocrine Biosciences (NBIX) vs. Royalty Pharma (RPRX): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Neurocrine Biosciences (NBIX) and Royalty Pharma (RPRX)
MetricNBIXRPRX
Revenue Growth (YoY)21.45%5.06%
Revenue Growth (3Y CAGR)24.32%2.06%
EPS Growth (YoY)41.95%23.09%
EPS Growth (3Y CAGR)44.12%161.10%

Financial Strength

Current Ratio (MRQ)

Both Neurocrine Biosciences (NBIX) at 2.04 and Royalty Pharma (RPRX) at 1.29 run current ratio in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.

NBIX

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.04

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
NBIX
2.04
Min
0.10

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.29

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
RPRX
1.29
Min
0.10
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Neurocrine Biosciences (NBIX) vs. Royalty Pharma (RPRX): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Neurocrine Biosciences (NBIX) at 0.12 carries an industry-typical debt-to-equity mix, while Royalty Pharma (RPRX) at 0.88 uses more debt funding than most peers.

NBIX

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.12

Max
1.42
Q3
0.65
Median
0.15
NBIX
0.12
Q1
0.02
Min
0.00

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.88

Max
1.42
RPRX
0.88
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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Neurocrine Biosciences (NBIX) vs. Royalty Pharma (RPRX): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Neurocrine Biosciences (NBIX) and Royalty Pharma (RPRX)
MetricNBIXRPRX
Current Ratio (MRQ)2.041.29
Debt / Equity (MRQ)0.120.88
Net Debt / EBITDA-0.274.76

Dividends

Dividend Yield (TTM)

Neurocrine Biosciences (NBIX) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Royalty Pharma (RPRX) reports a yield of 1.37%, ranking against industry peers normally.

NBIX

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

NBIX
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.37%

RPRX
1.37%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Neurocrine Biosciences (NBIX) vs. Royalty Pharma (RPRX): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Neurocrine Biosciences (NBIX) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Royalty Pharma (RPRX) reports a payout of 60.46%, ranking against industry peers normally.

NBIX

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

NBIX
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

60.46%

RPRX
60.46%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Neurocrine Biosciences (NBIX) vs. Royalty Pharma (RPRX): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Neurocrine Biosciences (NBIX) and Royalty Pharma (RPRX)
MetricNBIXRPRX
Dividend Yield (TTM)0.00%1.37%
Dividend Payout Ratio (TTM)0.00%60.46%

Valuation

P/E Ratio (TTM)

Neurocrine Biosciences (NBIX) at 24.43 is near its industry’s usual P/E ratio, while Royalty Pharma (RPRX) at 43.99 sits in the richer quartile — RPRX needs stronger growth or earnings quality to justify the premium.

NBIX

Pharmaceuticals, Biotechnology & Life Sciences industry group

24.43

Max
85.34
Q3
43.46
Median
26.69
NBIX
24.43
Q1
13.30
Min
0.07

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

43.99

Max
85.34
RPRX
43.99
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
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Neurocrine Biosciences (NBIX) vs. Royalty Pharma (RPRX): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

On P/S ratio, both Neurocrine Biosciences (NBIX) at 4.50 and Royalty Pharma (RPRX) at 14.79 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

NBIX

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.50

Max
58.18
Q3
25.77
Median
7.30
NBIX
4.50
Q1
3.01
Min
0.01

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

14.79

Max
58.18
Q3
25.77
RPRX
14.79
Median
7.30
Q1
3.01
Min
0.01
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Neurocrine Biosciences (NBIX) vs. Royalty Pharma (RPRX): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

On P/B ratio, both Neurocrine Biosciences (NBIX) at 4.30 and Royalty Pharma (RPRX) at 4.39 are valued close to their industries’ norm against book — neither stands out from peers.

NBIX

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.30

Max
13.53
Q3
6.54
NBIX
4.30
Median
3.25
Q1
1.69
Min
-5.59

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.39

Max
13.53
Q3
6.54
RPRX
4.39
Median
3.25
Q1
1.69
Min
-5.59
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Neurocrine Biosciences (NBIX) vs. Royalty Pharma (RPRX): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Neurocrine Biosciences (NBIX) and Royalty Pharma (RPRX)
MetricNBIXRPRX
P/E Ratio (TTM)24.4343.99
P/S Ratio (TTM)4.5014.79
P/B Ratio (MRQ)4.304.39
Free Cash Flow Yield (TTM)6.11%-1.16%