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MRNA vs. TAK: Moderna vs. Takeda Pharmaceutical Stock Comparison

How do Moderna (MRNA) and Takeda Pharmaceutical (TAK) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Moderna (MRNA) and Takeda Pharmaceutical (TAK) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but MRNA is classified in Biotechnology while TAK is classified in Pharmaceuticals.

Moderna (MRNA) trades as ordinary local shares, while Takeda Pharmaceutical (TAK) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.

Company profile comparison for Moderna (MRNA) and Takeda Pharmaceutical (TAK)
Profile ItemMRNATAK
NameModerna Inc.Takeda Pharmaceutical Co Ltd ADR
Country/RegionUnited StatesJapan
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyPharmaceuticals
GICS Sub-IndustryBiotechnologyPharmaceuticals
Market Capitalization101.48 billion USD67.16 billion USD
CurrencyUSDUSD
ExchangeNasdaqNYSE
Listing DateDecember 7, 2018January 5, 2010
Security TypeCommon StockADR

Price Performance

Cumulative Growth

MRNA
TAK
GSPC
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Moderna (MRNA) vs. Takeda Pharmaceutical (TAK), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Moderna (MRNA) and Takeda Pharmaceutical (TAK). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Moderna (MRNA) and Takeda Pharmaceutical (TAK). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Moderna (MRNA) and Takeda Pharmaceutical (TAK)
MetricMRNATAK
Total Return (1Y)1,031.66%54.54%
Total Return (3Y, Annualized)58.68%18.39%
Total Return (5Y, Annualized)3.23%9.29%

Risk Profile

Drawdown History

MRNA
TAK
GSPC
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Moderna (MRNA) vs. Takeda Pharmaceutical (TAK), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Moderna (MRNA) and Takeda Pharmaceutical (TAK). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Takeda Pharmaceutical (TAK) reports a negative beta of -0.01, suggesting inverse market sensitivity over the measurement window. That is uncommon for ordinary equities and can reflect commodity-linked or hedge-like exposure, but it can also come from statistical noise. Moderna (MRNA) has a non-negative beta of 1.08.

Risk profile metrics for Moderna (MRNA) and Takeda Pharmaceutical (TAK)
MetricMRNATAK
Volatility (1Y, Annualized)194.88%21.45%
Beta (5Y)1.08-0.01
Max Drawdown (5Y)-93.93%-24.83%
Avg. Volume (3M)21.61M2.61M

Risk-Adjusted Performance

Risk-Return Positioning

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MRNA and TAK are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Moderna (MRNA) and Takeda Pharmaceutical (TAK)
MetricMRNATAK
Sharpe Ratio (1Y)5.272.34
Sortino Ratio (1Y)20.443.88

Profitability

ROE (TTM)

Moderna (MRNA) reports a negative ROE of -39.00%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile Takeda Pharmaceutical (TAK) reports 0.56%, ranking against industry peers normally.

MRNA

Pharmaceuticals, Biotechnology & Life Sciences industry group

-39.00%

Max
109.18%
Q3
6.23%
Median
-26.66%
MRNA
-39.00%
Q1
-64.05%
Min
-167.77%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.56%

Max
109.18%
Q3
6.23%
TAK
0.56%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Moderna (MRNA) vs. Takeda Pharmaceutical (TAK): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Moderna (MRNA) reports a negative net margin of -141.43%, usually indicating a net loss over the period. Meanwhile Takeda Pharmaceutical (TAK) reports 0.87%, ranking against industry peers normally.

MRNA

Pharmaceuticals, Biotechnology & Life Sciences industry group

-141.43%

Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
MRNA
-141.43%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.87%

Max
18.05%
Q3
4.78%
TAK
0.87%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Moderna (MRNA) vs. Takeda Pharmaceutical (TAK): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Moderna (MRNA) reports a negative operating margin of -557.93%, usually indicating that operating costs exceeded revenue at the operating-income line. Meanwhile Takeda Pharmaceutical (TAK) reports 24.55%, ranking against industry peers normally.

MRNA

Pharmaceuticals, Biotechnology & Life Sciences industry group

-557.93%

Max
83.12%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
MRNA
-557.93%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

24.55%

Max
83.12%
TAK
24.55%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Moderna (MRNA) vs. Takeda Pharmaceutical (TAK): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Moderna (MRNA) and Takeda Pharmaceutical (TAK)
MetricMRNATAK
ROE (TTM)-39.00%0.56%
ROA (TTM)-13.26%3.27%
Net Margin (TTM)-141.43%0.87%
Operating Margin (TTM)-557.93%24.55%
Gross Margin (TTM)-66.02%64.77%

Growth

Revenue Growth

Both Moderna (MRNA) at -39.92% and Takeda Pharmaceutical (TAK) at -1.66% post bottom-quartile revenue growth versus peers, pointing to weaker demand or pricing momentum than typical rivals.

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Moderna (MRNA) vs. Takeda Pharmaceutical (TAK): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: Takeda Pharmaceutical (TAK) reports EPS growth of 77.96%, ranked against its industry; Moderna (MRNA) has no EPS growth figure this period.

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Moderna (MRNA) vs. Takeda Pharmaceutical (TAK): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Moderna (MRNA) and Takeda Pharmaceutical (TAK)
MetricMRNATAK
Revenue Growth (YoY)-39.92%-1.66%
Revenue Growth (3Y CAGR)-53.30%3.81%
EPS Growth (YoY)--77.96%
EPS Growth (3Y CAGR)---16.01%

Financial Strength

Current Ratio (MRQ)

Both Moderna (MRNA) at 2.30 and Takeda Pharmaceutical (TAK) at 1.15 run current ratio in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.

MRNA

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.30

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
MRNA
2.30
Min
0.10

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.15

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
TAK
1.15
Min
0.10
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Moderna (MRNA) vs. Takeda Pharmaceutical (TAK): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Moderna (MRNA) at 0.19 carries an industry-typical debt-to-equity mix, while Takeda Pharmaceutical (TAK) at 0.72 uses more debt funding than most peers.

MRNA

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.19

Max
1.42
Q3
0.65
MRNA
0.19
Median
0.15
Q1
0.02
Min
0.00

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.72

Max
1.42
TAK
0.72
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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Moderna (MRNA) vs. Takeda Pharmaceutical (TAK): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Moderna (MRNA) and Takeda Pharmaceutical (TAK)
MetricMRNATAK
Current Ratio (MRQ)2.301.15
Debt / Equity (MRQ)0.190.72
Net Debt / EBITDA--3.61

Dividends

Dividend Yield (TTM)

Moderna (MRNA) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Takeda Pharmaceutical (TAK) reports a yield of 953.28%, ranking against industry peers normally.

MRNA

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

MRNA
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

953.28%

TAK
953.28%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Moderna (MRNA) vs. Takeda Pharmaceutical (TAK): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Takeda Pharmaceutical (TAK) reports payout ratio above 100% at 426.53%, meaning dividends exceeded current-period earnings; Moderna (MRNA) pays no dividend (payout 0.00%).

MRNA

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

MRNA
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

426.53%

TAK
426.53%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Moderna (MRNA) vs. Takeda Pharmaceutical (TAK): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Moderna (MRNA) and Takeda Pharmaceutical (TAK)
MetricMRNATAK
Dividend Yield (TTM)0.00%953.28%
Dividend Payout Ratio (TTM)0.00%426.53%

Valuation

P/E Ratio (TTM)

An earnings multiple is available for just one side: Takeda Pharmaceutical (TAK) trades at 300.29 times trailing earnings, ranked against its peers, while Moderna (MRNA) has no P/E ratio this period.

MRNA

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
MRNA
--

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

300.29

TAK
300.29
Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
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Moderna (MRNA) vs. Takeda Pharmaceutical (TAK): MRNA does not report P/E ratio, so it has no value marker; TAK is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

P/S Ratio (TTM)

Takeda Pharmaceutical (TAK) at 0.01 looks cheap on sales in the lower P/S ratio quartile, while Moderna (MRNA) at 45.55 looks rich in the upper quartile — a clear gap in price per dollar of revenue.

MRNA

Pharmaceuticals, Biotechnology & Life Sciences industry group

45.55

Max
58.18
MRNA
45.55
Q3
25.77
Median
7.30
Q1
3.01
Min
0.01

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.01

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
TAK
0.01
Min
0.01
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Moderna (MRNA) vs. Takeda Pharmaceutical (TAK): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Takeda Pharmaceutical (TAK) at 1.43 looks cheap against book in the lower P/B ratio quartile, while Moderna (MRNA) at 11.58 carries a premium in the upper quartile — a clear price-to-book gap.

MRNA

Pharmaceuticals, Biotechnology & Life Sciences industry group

11.58

Max
13.53
MRNA
11.58
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.43

Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
TAK
1.43
Min
-5.59
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Moderna (MRNA) vs. Takeda Pharmaceutical (TAK): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Moderna (MRNA) and Takeda Pharmaceutical (TAK)
MetricMRNATAK
P/E Ratio (TTM)--300.29
P/S Ratio (TTM)45.550.01
P/B Ratio (MRQ)11.581.43
Free Cash Flow Yield (TTM)0.29%1,014.61%