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KYMR vs. PFE: Kymera Therapeutics vs. Pfizer Stock Comparison

How do Kymera Therapeutics (KYMR) and Pfizer (PFE) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Kymera Therapeutics (KYMR) and Pfizer (PFE) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but KYMR is classified in Biotechnology while PFE is classified in Pharmaceuticals.

Pfizer (PFE) has more than two decades of public-market history since June 1, 1972, whereas Kymera Therapeutics (KYMR) listed on August 21, 2020 and has a much shorter record to draw on.

Company profile comparison for Kymera Therapeutics (KYMR) and Pfizer (PFE)
Profile ItemKYMRPFE
NameKymera Therapeutics Inc.Pfizer Inc.
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyPharmaceuticals
GICS Sub-IndustryBiotechnologyPharmaceuticals
Market Capitalization11.25 billion USD167.52 billion USD
CurrencyUSDUSD
ExchangeNasdaqNYSE
Listing DateAugust 21, 2020June 1, 1972
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

KYMR
PFE
GSPC
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Kymera Therapeutics (KYMR) vs. Pfizer (PFE), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Kymera Therapeutics (KYMR) and Pfizer (PFE). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Kymera Therapeutics (KYMR) and Pfizer (PFE). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Kymera Therapeutics (KYMR) and Pfizer (PFE)
MetricKYMRPFE
Total Return (1Y)131.52%28.65%
Total Return (3Y, Annualized)111.65%6.41%
Total Return (5Y, Annualized)15.68%-3.98%

Risk Profile

Drawdown History

KYMR
PFE
GSPC
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Kymera Therapeutics (KYMR) vs. Pfizer (PFE), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Kymera Therapeutics (KYMR) and Pfizer (PFE). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Kymera Therapeutics (KYMR) has an aggressive beta of 2.00, indicating higher sensitivity to broad-market moves, while Pfizer (PFE) is defensive at 0.35 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.

Pfizer (PFE) is heavily traded at around 33.67M shares per day, whereas Kymera Therapeutics (KYMR) sees a more moderate 833.05K — larger orders in the latter may require more patience and tighter control over order sizing.

Risk profile metrics for Kymera Therapeutics (KYMR) and Pfizer (PFE)
MetricKYMRPFE
Volatility (1Y, Annualized)62.83%21.72%
Beta (5Y)2.000.35
Max Drawdown (5Y)-83.27%-58.96%
Avg. Volume (3M)833.05K33.67M

Risk-Adjusted Performance

Risk-Return Positioning

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KYMR and PFE are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Kymera Therapeutics (KYMR) and Pfizer (PFE)
MetricKYMRPFE
Sharpe Ratio (1Y)2.031.12
Sortino Ratio (1Y)4.161.73

Profitability

ROE (TTM)

Kymera Therapeutics (KYMR) reports a negative ROE of -27.29%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile Pfizer (PFE) reports 4.47%, ranking against industry peers normally.

KYMR

Pharmaceuticals, Biotechnology & Life Sciences industry group

-27.29%

Max
109.18%
Q3
6.23%
Median
-26.66%
KYMR
-27.29%
Q1
-64.05%
Min
-167.77%

PFE

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.47%

Max
109.18%
Q3
6.23%
PFE
4.47%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Kymera Therapeutics (KYMR) vs. Pfizer (PFE): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Pfizer (PFE) at 6.34% retains a top-quartile share of revenue as profit, ahead of Kymera Therapeutics (KYMR) at 0.00%, which keeps about the industry-typical share.

KYMR

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

Max
18.05%
Q3
4.78%
KYMR
0.00%
Median
0.00%
Q1
-4.14%
Min
-17.05%

PFE

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.34%

Max
18.05%
PFE
6.34%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Kymera Therapeutics (KYMR) vs. Pfizer (PFE): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Kymera Therapeutics (KYMR) reports a negative operating margin of -396.04%, usually indicating that operating costs exceeded revenue at the operating-income line. Meanwhile Pfizer (PFE) reports 33.38%, ranking against industry peers normally.

KYMR

Pharmaceuticals, Biotechnology & Life Sciences industry group

-396.04%

Max
83.12%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
KYMR
-396.04%

PFE

Pharmaceuticals, Biotechnology & Life Sciences industry group

33.38%

Max
83.12%
PFE
33.38%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Kymera Therapeutics (KYMR) vs. Pfizer (PFE): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Kymera Therapeutics (KYMR) and Pfizer (PFE)
MetricKYMRPFE
ROE (TTM)-27.29%4.47%
ROA (TTM)-17.64%5.59%
Net Margin (TTM)0.00%6.34%
Operating Margin (TTM)-396.04%33.38%
Gross Margin (TTM)0.00%74.90%

Growth

Revenue Growth

Both Kymera Therapeutics (KYMR) at -16.70% and Pfizer (PFE) at -1.65% post bottom-quartile revenue growth versus peers, pointing to weaker demand or pricing momentum than typical rivals.

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Kymera Therapeutics (KYMR) vs. Pfizer (PFE): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: Pfizer (PFE) reports EPS growth of -3.55%, ranked against its industry; Kymera Therapeutics (KYMR) has no EPS growth figure this period.

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Kymera Therapeutics (KYMR) vs. Pfizer (PFE): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Kymera Therapeutics (KYMR) and Pfizer (PFE)
MetricKYMRPFE
Revenue Growth (YoY)-16.70%-1.65%
Revenue Growth (3Y CAGR)-5.74%-14.80%
EPS Growth (YoY)---3.55%
EPS Growth (3Y CAGR)---37.12%

Financial Strength

Current Ratio (MRQ)

Kymera Therapeutics (KYMR) at 11.13 keeps current ratio within its industry’s typical mid-range, while Pfizer (PFE) at 1.42 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for PFE.

KYMR

Pharmaceuticals, Biotechnology & Life Sciences industry group

11.13

Max
25.13
Q3
12.13
KYMR
11.13
Median
5.52
Q1
2.47
Min
0.10

PFE

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.42

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
PFE
1.42
Min
0.10
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Kymera Therapeutics (KYMR) vs. Pfizer (PFE): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Kymera Therapeutics (KYMR) at 0.05 carries an industry-typical debt-to-equity mix, while Pfizer (PFE) at 0.71 uses more debt funding than most peers.

KYMR

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.05

Max
1.42
Q3
0.65
Median
0.15
KYMR
0.05
Q1
0.02
Min
0.00

PFE

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.71

Max
1.42
PFE
0.71
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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Kymera Therapeutics (KYMR) vs. Pfizer (PFE): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Kymera Therapeutics (KYMR) and Pfizer (PFE)
MetricKYMRPFE
Current Ratio (MRQ)11.131.42
Debt / Equity (MRQ)0.050.71
Net Debt / EBITDA--1.97

Dividends

Dividend Yield (TTM)

Kymera Therapeutics (KYMR) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Pfizer (PFE) reports a yield of 7.30%, ranking against industry peers normally.

KYMR

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

KYMR
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

PFE

Pharmaceuticals, Biotechnology & Life Sciences industry group

7.30%

PFE
7.30%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Kymera Therapeutics (KYMR) vs. Pfizer (PFE): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Pfizer (PFE) reports payout ratio above 100% at 245.71%, meaning dividends exceeded current-period earnings; Kymera Therapeutics (KYMR) pays no dividend (payout 0.00%).

KYMR

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

KYMR
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

PFE

Pharmaceuticals, Biotechnology & Life Sciences industry group

245.71%

PFE
245.71%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Kymera Therapeutics (KYMR) vs. Pfizer (PFE): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Kymera Therapeutics (KYMR) and Pfizer (PFE)
MetricKYMRPFE
Dividend Yield (TTM)0.00%7.30%
Dividend Payout Ratio (TTM)0.00%245.71%

Valuation

P/E Ratio (TTM)

An earnings multiple is available for just one side: Pfizer (PFE) trades at 41.99 times trailing earnings, ranked against its peers, while Kymera Therapeutics (KYMR) has no P/E ratio this period.

KYMR

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
KYMR
--

PFE

Pharmaceuticals, Biotechnology & Life Sciences industry group

41.99

Max
85.34
Q3
43.46
PFE
41.99
Median
26.69
Q1
13.30
Min
0.07
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Kymera Therapeutics (KYMR) vs. Pfizer (PFE): KYMR does not report P/E ratio, so it has no value marker; PFE is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

P/S Ratio (TTM)

Pfizer (PFE) at 2.63 sits in the cheaper P/S ratio quartile while Kymera Therapeutics (KYMR) at 110.00 prices above its industry range — a wide gap in sales valuation between them.

KYMR

Pharmaceuticals, Biotechnology & Life Sciences industry group

110.00

KYMR
110.00
Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
Min
0.01

PFE

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.63

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
PFE
2.63
Min
0.01
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Kymera Therapeutics (KYMR) vs. Pfizer (PFE): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Pfizer (PFE) at 1.88 is valued about in line with its industry on P/B ratio, while Kymera Therapeutics (KYMR) at 6.96 carries an above-peer premium to book — KYMR is pricier on assets.

KYMR

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.96

Max
13.53
KYMR
6.96
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

PFE

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.88

Max
13.53
Q3
6.54
Median
3.25
PFE
1.88
Q1
1.69
Min
-5.59
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Kymera Therapeutics (KYMR) vs. Pfizer (PFE): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Kymera Therapeutics (KYMR) and Pfizer (PFE)
MetricKYMRPFE
P/E Ratio (TTM)--41.99
P/S Ratio (TTM)110.002.63
P/B Ratio (MRQ)6.961.88
Free Cash Flow Yield (TTM)-1.46%7.76%