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JAZZ vs. VRTX: Jazz Pharmaceuticals vs. Vertex Pharmaceuticals Stock Comparison

How do Jazz Pharmaceuticals (JAZZ) and Vertex Pharmaceuticals (VRTX) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Jazz Pharmaceuticals (JAZZ) and Vertex Pharmaceuticals (VRTX) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but JAZZ is classified in Pharmaceuticals while VRTX is classified in Biotechnology.

Company profile comparison for Jazz Pharmaceuticals (JAZZ) and Vertex Pharmaceuticals (VRTX)
Profile ItemJAZZVRTX
NameJazz Pharmaceuticals plcVertex Pharmaceuticals Incorporated Common Stock
Country/RegionIrelandUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryPharmaceuticalsBiotechnology
GICS Sub-IndustryPharmaceuticalsBiotechnology
Market Capitalization15.07 billion USD138.71 billion USD
CurrencyUSDUSD
ExchangeNasdaqNasdaq
Listing DateJune 1, 2007July 24, 1991
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

JAZZ
VRTX
GSPC
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Jazz Pharmaceuticals (JAZZ) vs. Vertex Pharmaceuticals (VRTX), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Jazz Pharmaceuticals (JAZZ) and Vertex Pharmaceuticals (VRTX). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Jazz Pharmaceuticals (JAZZ) and Vertex Pharmaceuticals (VRTX). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Jazz Pharmaceuticals (JAZZ) and Vertex Pharmaceuticals (VRTX)
MetricJAZZVRTX
Total Return (1Y)84.44%34.89%
Total Return (3Y, Annualized)27.57%14.44%
Total Return (5Y, Annualized)12.88%23.65%

Risk Profile

Drawdown History

JAZZ
VRTX
GSPC
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Jazz Pharmaceuticals (JAZZ) vs. Vertex Pharmaceuticals (VRTX), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Jazz Pharmaceuticals (JAZZ) and Vertex Pharmaceuticals (VRTX). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Jazz Pharmaceuticals (JAZZ) and Vertex Pharmaceuticals (VRTX)
MetricJAZZVRTX
Volatility (1Y, Annualized)38.74%29.73%
Beta (5Y)0.330.29
Max Drawdown (5Y)-42.03%-29.07%
Avg. Volume (3M)878.80K1.25M

Risk-Adjusted Performance

Risk-Return Positioning

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JAZZ and VRTX are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Jazz Pharmaceuticals (JAZZ) and Vertex Pharmaceuticals (VRTX)
MetricJAZZVRTX
Sharpe Ratio (1Y)2.071.03
Sortino Ratio (1Y)4.141.68

Profitability

ROE (TTM)

Vertex Pharmaceuticals (VRTX) at 20.80% sits in the top ROE quartile, while Jazz Pharmaceuticals (JAZZ) at 5.05% is closer to the peer norm — stronger capital efficiency for VRTX.

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.05%

Max
109.18%
Q3
6.23%
JAZZ
5.05%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

20.80%

Max
109.18%
VRTX
20.80%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Jazz Pharmaceuticals (JAZZ) vs. Vertex Pharmaceuticals (VRTX): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Vertex Pharmaceuticals (VRTX) at 30.70% converts revenue to bottom-line profit above its industry’s benchmark range, while Jazz Pharmaceuticals (JAZZ) at 4.37% keeps roughly the typical share for its industry.

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.37%

Max
18.05%
Q3
4.78%
JAZZ
4.37%
Median
0.00%
Q1
-4.14%
Min
-17.05%

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

30.70%

VRTX
30.70%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Jazz Pharmaceuticals (JAZZ) vs. Vertex Pharmaceuticals (VRTX): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Jazz Pharmaceuticals (JAZZ) at 30.17% and Vertex Pharmaceuticals (VRTX) at 35.57% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

30.17%

Max
83.12%
JAZZ
30.17%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

35.57%

Max
83.12%
VRTX
35.57%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Jazz Pharmaceuticals (JAZZ) vs. Vertex Pharmaceuticals (VRTX): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Jazz Pharmaceuticals (JAZZ) and Vertex Pharmaceuticals (VRTX)
MetricJAZZVRTX
ROE (TTM)5.05%20.80%
ROA (TTM)6.92%10.62%
Net Margin (TTM)4.37%30.70%
Operating Margin (TTM)30.17%35.57%
Gross Margin (TTM)91.10%54.81%

Growth

Revenue Growth

Both Jazz Pharmaceuticals (JAZZ) at 4.88% and Vertex Pharmaceuticals (VRTX) at 8.90% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

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Jazz Pharmaceuticals (JAZZ) vs. Vertex Pharmaceuticals (VRTX): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: Jazz Pharmaceuticals (JAZZ) reports EPS growth of -167.51%, ranked against its industry; Vertex Pharmaceuticals (VRTX) has no EPS growth figure this period.

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Jazz Pharmaceuticals (JAZZ) vs. Vertex Pharmaceuticals (VRTX): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Jazz Pharmaceuticals (JAZZ) and Vertex Pharmaceuticals (VRTX)
MetricJAZZVRTX
Revenue Growth (YoY)4.88%8.90%
Revenue Growth (3Y CAGR)5.26%10.35%
EPS Growth (YoY)-167.51%--
EPS Growth (3Y CAGR)--6.12%

Financial Strength

Current Ratio (MRQ)

Both Jazz Pharmaceuticals (JAZZ) at 1.82 and Vertex Pharmaceuticals (VRTX) at 2.34 run current ratio in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.82

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
JAZZ
1.82
Min
0.10

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.34

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
VRTX
2.34
Min
0.10
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Jazz Pharmaceuticals (JAZZ) vs. Vertex Pharmaceuticals (VRTX): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Vertex Pharmaceuticals (VRTX) at 0.31 carries an industry-typical debt-to-equity mix, while Jazz Pharmaceuticals (JAZZ) at 1.35 uses more debt funding than most peers.

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.35

Max
1.42
JAZZ
1.35
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.31

Max
1.42
Q3
0.65
VRTX
0.31
Median
0.15
Q1
0.02
Min
0.00
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Jazz Pharmaceuticals (JAZZ) vs. Vertex Pharmaceuticals (VRTX): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Jazz Pharmaceuticals (JAZZ) and Vertex Pharmaceuticals (VRTX)
MetricJAZZVRTX
Current Ratio (MRQ)1.822.34
Debt / Equity (MRQ)1.350.31
Net Debt / EBITDA1.390.03

Dividends

Dividend Yield (TTM)

Neither Jazz Pharmaceuticals (JAZZ) nor Vertex Pharmaceuticals (VRTX) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

JAZZ
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

VRTX
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Jazz Pharmaceuticals (JAZZ) vs. Vertex Pharmaceuticals (VRTX): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Neither Jazz Pharmaceuticals (JAZZ) nor Vertex Pharmaceuticals (VRTX) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

JAZZ
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

VRTX
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Jazz Pharmaceuticals (JAZZ) vs. Vertex Pharmaceuticals (VRTX): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Jazz Pharmaceuticals (JAZZ) and Vertex Pharmaceuticals (VRTX)
MetricJAZZVRTX
Dividend Yield (TTM)0.00%0.00%
Dividend Payout Ratio (TTM)0.00%0.00%

Valuation

P/E Ratio (TTM)

Vertex Pharmaceuticals (VRTX) at 35.21 is near its industry’s usual P/E ratio, while Jazz Pharmaceuticals (JAZZ) at 69.46 sits in the richer quartile — JAZZ needs stronger growth or earnings quality to justify the premium.

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

69.46

Max
85.34
JAZZ
69.46
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

35.21

Max
85.34
Q3
43.46
VRTX
35.21
Median
26.69
Q1
13.30
Min
0.07
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Jazz Pharmaceuticals (JAZZ) vs. Vertex Pharmaceuticals (VRTX): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

On P/S ratio, both Jazz Pharmaceuticals (JAZZ) at 3.19 and Vertex Pharmaceuticals (VRTX) at 10.71 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.19

Max
58.18
Q3
25.77
Median
7.30
JAZZ
3.19
Q1
3.01
Min
0.01

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

10.71

Max
58.18
Q3
25.77
VRTX
10.71
Median
7.30
Q1
3.01
Min
0.01
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Jazz Pharmaceuticals (JAZZ) vs. Vertex Pharmaceuticals (VRTX): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Jazz Pharmaceuticals (JAZZ) at 3.59 is valued about in line with its industry on P/B ratio, while Vertex Pharmaceuticals (VRTX) at 6.63 carries an above-peer premium to book — VRTX is pricier on assets.

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.59

Max
13.53
Q3
6.54
JAZZ
3.59
Median
3.25
Q1
1.69
Min
-5.59

VRTX

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.63

Max
13.53
VRTX
6.63
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
Loading chart…
Jazz Pharmaceuticals (JAZZ) vs. Vertex Pharmaceuticals (VRTX): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Jazz Pharmaceuticals (JAZZ) and Vertex Pharmaceuticals (VRTX)
MetricJAZZVRTX
P/E Ratio (TTM)69.4635.21
P/S Ratio (TTM)3.1910.71
P/B Ratio (MRQ)3.596.63
Free Cash Flow Yield (TTM)11.16%1.69%