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INSM vs. WAT: Insmed vs. Waters Stock Comparison

How do Insmed (INSM) and Waters (WAT) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Insmed (INSM) and Waters (WAT) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but INSM is classified in Biotechnology while WAT is classified in Life Sciences Tools & Services.

Company profile comparison for Insmed (INSM) and Waters (WAT)
Profile ItemINSMWAT
NameInsmed IncorporatedWaters Corporation
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyLife Sciences Tools & Services
GICS Sub-IndustryBiotechnologyLife Sciences Tools & Services
Market Capitalization25.10 billion USD44.93 billion USD
CurrencyUSDUSD
ExchangeNasdaqNYSE
Listing DateJune 1, 2000November 17, 1995
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

INSM
WAT
GSPC
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Insmed (INSM) vs. Waters (WAT), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Insmed (INSM) and Waters (WAT). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Insmed (INSM) and Waters (WAT). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Insmed (INSM) and Waters (WAT)
MetricINSMWAT
Total Return (1Y)-39.17%27.70%
Total Return (3Y, Annualized)70.17%23.32%
Total Return (5Y, Annualized)28.96%6.27%

Risk Profile

Drawdown History

INSM
WAT
GSPC
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Insmed (INSM) vs. Waters (WAT), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Insmed (INSM) and Waters (WAT). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Insmed (INSM) and Waters (WAT)
MetricINSMWAT
Volatility (1Y, Annualized)63.09%35.45%
Beta (5Y)0.801.13
Max Drawdown (5Y)-56.54%-36.47%
Avg. Volume (3M)2.76M816.72K

Risk-Adjusted Performance

Risk-Return Positioning

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INSM and WAT are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Insmed (INSM) and Waters (WAT)
MetricINSMWAT
Sharpe Ratio (1Y)-0.690.66
Sortino Ratio (1Y)-1.040.98

Profitability

ROE (TTM)

Insmed (INSM) reports a negative ROE of -72.45%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile Waters (WAT) reports 1.12%, ranking against industry peers normally.

INSM

Pharmaceuticals, Biotechnology & Life Sciences industry group

-72.45%

Max
109.18%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
INSM
-72.45%
Min
-167.77%

WAT

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.12%

Max
109.18%
Q3
6.23%
WAT
1.12%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Insmed (INSM) vs. Waters (WAT): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Insmed (INSM) reports a negative net margin of -39.85%, usually indicating a net loss over the period. Meanwhile Waters (WAT) reports 1.76%, ranking against industry peers normally.

INSM

Pharmaceuticals, Biotechnology & Life Sciences industry group

-39.85%

Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
INSM
-39.85%

WAT

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.76%

Max
18.05%
Q3
4.78%
WAT
1.76%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Insmed (INSM) vs. Waters (WAT): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Insmed (INSM) reports a negative operating margin of -15.60%, usually indicating that operating costs exceeded revenue at the operating-income line. Meanwhile Waters (WAT) reports 11.38%, ranking against industry peers normally.

INSM

Pharmaceuticals, Biotechnology & Life Sciences industry group

-15.60%

Max
83.12%
Q3
14.77%
Median
0.00%
INSM
-15.60%
Q1
-78.82%
Min
-207.40%

WAT

Pharmaceuticals, Biotechnology & Life Sciences industry group

11.38%

Max
83.12%
Q3
14.77%
WAT
11.38%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Insmed (INSM) vs. Waters (WAT): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Insmed (INSM) and Waters (WAT)
MetricINSMWAT
ROE (TTM)-72.45%1.12%
ROA (TTM)-17.25%2.36%
Net Margin (TTM)-39.85%1.76%
Operating Margin (TTM)-15.60%11.38%
Gross Margin (TTM)84.40%49.83%

Growth

Revenue Growth

Insmed (INSM) at 66.73% sits in the top revenue growth quartile, while Waters (WAT) at 6.99% is closer to the peer norm — faster top-line expansion for INSM.

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Insmed (INSM) vs. Waters (WAT): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: Waters (WAT) reports EPS growth of 0.47%, ranked against its industry; Insmed (INSM) has no EPS growth figure this period.

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Insmed (INSM) vs. Waters (WAT): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Insmed (INSM) and Waters (WAT)
MetricINSMWAT
Revenue Growth (YoY)66.73%6.99%
Revenue Growth (3Y CAGR)35.20%2.12%
EPS Growth (YoY)--0.47%
EPS Growth (3Y CAGR)---2.84%

Financial Strength

Current Ratio (MRQ)

Short-term liquidity can only be read on one side of this pairing: Insmed (INSM) shows current ratio of 2.86 against its industry benchmark, while Waters (WAT) has no reading this period.

INSM

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.86

Max
25.13
Q3
12.13
Median
5.52
INSM
2.86
Q1
2.47
Min
0.10

WAT

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
Min
0.10
WAT
--
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Insmed (INSM) vs. Waters (WAT): WAT does not report current ratio, so it has no value marker; INSM is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

Debt / Equity (MRQ)

Waters (WAT) at 0.34 carries an industry-typical debt-to-equity mix, while Insmed (INSM) at 1.01 uses more debt funding than most peers.

INSM

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.01

Max
1.42
INSM
1.01
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

WAT

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.34

Max
1.42
Q3
0.65
WAT
0.34
Median
0.15
Q1
0.02
Min
0.00
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Insmed (INSM) vs. Waters (WAT): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Insmed (INSM) and Waters (WAT)
MetricINSMWAT
Current Ratio (MRQ)2.86--
Debt / Equity (MRQ)1.010.34
Net Debt / EBITDA--3.23

Dividends

Dividend Yield (TTM)

Neither Insmed (INSM) nor Waters (WAT) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

INSM

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

INSM
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

WAT

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

WAT
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Insmed (INSM) vs. Waters (WAT): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Neither Insmed (INSM) nor Waters (WAT) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

INSM

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

INSM
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

WAT

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

WAT
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Insmed (INSM) vs. Waters (WAT): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Insmed (INSM) and Waters (WAT)
MetricINSMWAT
Dividend Yield (TTM)0.00%0.00%
Dividend Payout Ratio (TTM)0.00%0.00%

Valuation

P/E Ratio (TTM)

An earnings multiple is available for just one side: Waters (WAT) trades at 191.46 times trailing earnings, ranked against its peers, while Insmed (INSM) has no P/E ratio this period.

INSM

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
INSM
--

WAT

Pharmaceuticals, Biotechnology & Life Sciences industry group

191.46

WAT
191.46
Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
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Insmed (INSM) vs. Waters (WAT): INSM does not report P/E ratio, so it has no value marker; WAT is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

P/S Ratio (TTM)

On P/S ratio, both Insmed (INSM) at 16.52 and Waters (WAT) at 8.01 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

INSM

Pharmaceuticals, Biotechnology & Life Sciences industry group

16.52

Max
58.18
Q3
25.77
INSM
16.52
Median
7.30
Q1
3.01
Min
0.01

WAT

Pharmaceuticals, Biotechnology & Life Sciences industry group

8.01

Max
58.18
Q3
25.77
WAT
8.01
Median
7.30
Q1
3.01
Min
0.01
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Insmed (INSM) vs. Waters (WAT): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Waters (WAT) at 2.94 sits near its industry’s typical P/B ratio, while Insmed (INSM) at 34.55 prices above its benchmark range — INSM looks rich relative to book.

INSM

Pharmaceuticals, Biotechnology & Life Sciences industry group

34.55

INSM
34.55
Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

WAT

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.94

Max
13.53
Q3
6.54
Median
3.25
WAT
2.94
Q1
1.69
Min
-5.59
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Insmed (INSM) vs. Waters (WAT): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Insmed (INSM) and Waters (WAT)
MetricINSMWAT
P/E Ratio (TTM)--191.46
P/S Ratio (TTM)16.528.01
P/B Ratio (MRQ)34.552.94
Free Cash Flow Yield (TTM)-1.82%--