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ILMN vs. SMMT: Illumina vs. Summit Therapeutics Stock Comparison

How do Illumina (ILMN) and Summit Therapeutics (SMMT) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Illumina (ILMN) and Summit Therapeutics (SMMT) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but ILMN is classified in Life Sciences Tools & Services while SMMT is classified in Biotechnology.

Company profile comparison for Illumina (ILMN) and Summit Therapeutics (SMMT)
Profile ItemILMNSMMT
NameIllumina Inc.Summit Therapeutics Inc.
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryLife Sciences Tools & ServicesBiotechnology
GICS Sub-IndustryLife Sciences Tools & ServicesBiotechnology
Market Capitalization32.23 billion USD13.06 billion USD
CurrencyUSDUSD
ExchangeNasdaqNasdaq
Listing DateJuly 28, 2000March 5, 2015
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

ILMN
SMMT
GSPC
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Illumina (ILMN) vs. Summit Therapeutics (SMMT), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Illumina (ILMN) and Summit Therapeutics (SMMT). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Illumina (ILMN) and Summit Therapeutics (SMMT). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Illumina (ILMN) and Summit Therapeutics (SMMT)
MetricILMNSMMT
Total Return (1Y)79.70%-2.48%
Total Return (3Y, Annualized)28.16%116.18%
Total Return (5Y, Annualized)-10.65%26.89%

Risk Profile

Drawdown History

ILMN
SMMT
GSPC
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Illumina (ILMN) vs. Summit Therapeutics (SMMT), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Illumina (ILMN) and Summit Therapeutics (SMMT). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Summit Therapeutics (SMMT) reports a negative beta of -1.51, suggesting inverse market sensitivity over the measurement window. That is uncommon for ordinary equities and can reflect commodity-linked or hedge-like exposure, but it can also come from statistical noise. Illumina (ILMN) has a non-negative beta of 1.46.

Risk profile metrics for Illumina (ILMN) and Summit Therapeutics (SMMT)
MetricILMNSMMT
Volatility (1Y, Annualized)48.47%75.06%
Beta (5Y)1.46-1.51
Max Drawdown (5Y)-82.95%-87.64%
Avg. Volume (3M)2.77M6.19M

Risk-Adjusted Performance

Risk-Return Positioning

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ILMN and SMMT are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Illumina (ILMN) and Summit Therapeutics (SMMT)
MetricILMNSMMT
Sharpe Ratio (1Y)1.56-0.09
Sortino Ratio (1Y)2.25-0.13

Profitability

ROE (TTM)

Summit Therapeutics (SMMT) reports a negative ROE of -220.01%; negative ROE can reflect losses or negative shareholders’ equity, so it is harder to read as capital efficiency. Meanwhile Illumina (ILMN) reports 32.39%, ranking against industry peers normally.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

32.39%

Max
109.18%
ILMN
32.39%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

SMMT

Pharmaceuticals, Biotechnology & Life Sciences industry group

-220.01%

Max
109.18%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
SMMT
-220.01%
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Illumina (ILMN) vs. Summit Therapeutics (SMMT): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Illumina (ILMN) at 19.72% converts revenue to bottom-line profit above its industry’s benchmark range, while Summit Therapeutics (SMMT) at 0.00% keeps roughly the typical share for its industry.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

19.72%

ILMN
19.72%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

SMMT

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

Max
18.05%
Q3
4.78%
SMMT
0.00%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Illumina (ILMN) vs. Summit Therapeutics (SMMT): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Illumina (ILMN) at 20.02% operates in the top operating margin quartile, ahead of Summit Therapeutics (SMMT) at 0.00%, which runs around its industry’s norm.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

20.02%

Max
83.12%
ILMN
20.02%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

SMMT

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

Max
83.12%
Q3
14.77%
SMMT
0.00%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Illumina (ILMN) vs. Summit Therapeutics (SMMT): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Illumina (ILMN) and Summit Therapeutics (SMMT)
MetricILMNSMMT
ROE (TTM)32.39%-220.01%
ROA (TTM)8.32%-111.99%
Net Margin (TTM)19.72%0.00%
Operating Margin (TTM)20.02%0.00%
Gross Margin (TTM)67.68%0.00%

Growth

Revenue Growth

Only one side can be read here: Illumina (ILMN) reports revenue growth of -0.66%, ranked against its industry; Summit Therapeutics (SMMT) has no revenue growth figure this period.

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Illumina (ILMN) vs. Summit Therapeutics (SMMT): A comparison of their Revenue Growth across different time periods.

EPS Growth

Neither Illumina (ILMN) nor Summit Therapeutics (SMMT) reports a EPS growth value for this period, so a direct comparison isn't possible.

Growth Metrics

Growth metrics for Illumina (ILMN) and Summit Therapeutics (SMMT)
MetricILMNSMMT
Revenue Growth (YoY)-0.66%--
Revenue Growth (3Y CAGR)-1.78%--
EPS Growth (YoY)----
EPS Growth (3Y CAGR)----

Financial Strength

Current Ratio (MRQ)

Both Illumina (ILMN) at 2.63 and Summit Therapeutics (SMMT) at 5.99 carry current ratio within their industries’ typical mid-ranges, suggesting balanced short-term liquidity relative to peers.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.63

Max
25.13
Q3
12.13
Median
5.52
ILMN
2.63
Q1
2.47
Min
0.10

SMMT

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.99

Max
25.13
Q3
12.13
SMMT
5.99
Median
5.52
Q1
2.47
Min
0.10
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Illumina (ILMN) vs. Summit Therapeutics (SMMT): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Summit Therapeutics (SMMT) at 0.04 carries an industry-typical debt-to-equity mix, while Illumina (ILMN) at 0.74 uses more debt funding than most peers.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.74

Max
1.42
ILMN
0.74
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

SMMT

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.04

Max
1.42
Q3
0.65
Median
0.15
SMMT
0.04
Q1
0.02
Min
0.00
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Illumina (ILMN) vs. Summit Therapeutics (SMMT): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Illumina (ILMN) and Summit Therapeutics (SMMT)
MetricILMNSMMT
Current Ratio (MRQ)2.635.99
Debt / Equity (MRQ)0.740.04
Net Debt / EBITDA0.85--

Dividends

Dividend Yield (TTM)

Neither Illumina (ILMN) nor Summit Therapeutics (SMMT) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ILMN
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

SMMT

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

SMMT
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Illumina (ILMN) vs. Summit Therapeutics (SMMT): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Neither Illumina (ILMN) nor Summit Therapeutics (SMMT) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ILMN
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

SMMT

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

SMMT
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Illumina (ILMN) vs. Summit Therapeutics (SMMT): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Illumina (ILMN) and Summit Therapeutics (SMMT)
MetricILMNSMMT
Dividend Yield (TTM)0.00%0.00%
Dividend Payout Ratio (TTM)0.00%0.00%

Valuation

P/E Ratio (TTM)

An earnings multiple is available for just one side: Illumina (ILMN) trades at 36.68 times trailing earnings, ranked against its peers, while Summit Therapeutics (SMMT) has no P/E ratio this period.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

36.68

Max
85.34
Q3
43.46
ILMN
36.68
Median
26.69
Q1
13.30
Min
0.07

SMMT

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
SMMT
--
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Illumina (ILMN) vs. Summit Therapeutics (SMMT): SMMT does not report P/E ratio, so it has no value marker; ILMN is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

P/S Ratio (TTM)

A sales-based read is only available for Illumina (ILMN), whose P/S ratio of 7.10 ranks against industry peers; Summit Therapeutics (SMMT) reports no figure this period.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

7.10

Max
58.18
Q3
25.77
Median
7.30
ILMN
7.10
Q1
3.01
Min
0.01

SMMT

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
Min
0.01
SMMT
--
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Illumina (ILMN) vs. Summit Therapeutics (SMMT): SMMT does not report P/S ratio, so it has no value marker; ILMN is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

P/B Ratio (MRQ)

Both look rich against book: Illumina (ILMN) at 10.30 sits in the upper P/B ratio quartile, and Summit Therapeutics (SMMT) at 23.13 prices even higher, above its industry range.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

10.30

Max
13.53
ILMN
10.30
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

SMMT

Pharmaceuticals, Biotechnology & Life Sciences industry group

23.13

SMMT
23.13
Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
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Illumina (ILMN) vs. Summit Therapeutics (SMMT): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Illumina (ILMN) and Summit Therapeutics (SMMT)
MetricILMNSMMT
P/E Ratio (TTM)36.68--
P/S Ratio (TTM)7.10--
P/B Ratio (MRQ)10.3023.13
Free Cash Flow Yield (TTM)2.67%-1.64%