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ILMN vs. JAZZ: Illumina vs. Jazz Pharmaceuticals Stock Comparison

How do Illumina (ILMN) and Jazz Pharmaceuticals (JAZZ) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Illumina (ILMN) and Jazz Pharmaceuticals (JAZZ) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but ILMN is classified in Life Sciences Tools & Services while JAZZ is classified in Pharmaceuticals.

Company profile comparison for Illumina (ILMN) and Jazz Pharmaceuticals (JAZZ)
Profile ItemILMNJAZZ
NameIllumina Inc.Jazz Pharmaceuticals plc
Country/RegionUnited StatesIreland
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryLife Sciences Tools & ServicesPharmaceuticals
GICS Sub-IndustryLife Sciences Tools & ServicesPharmaceuticals
Market Capitalization32.23 billion USD15.07 billion USD
CurrencyUSDUSD
ExchangeNasdaqNasdaq
Listing DateJuly 28, 2000June 1, 2007
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

ILMN
JAZZ
GSPC
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Illumina (ILMN) vs. Jazz Pharmaceuticals (JAZZ), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Illumina (ILMN) and Jazz Pharmaceuticals (JAZZ). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Illumina (ILMN) and Jazz Pharmaceuticals (JAZZ). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Illumina (ILMN) and Jazz Pharmaceuticals (JAZZ)
MetricILMNJAZZ
Total Return (1Y)79.70%84.44%
Total Return (3Y, Annualized)28.16%27.57%
Total Return (5Y, Annualized)-10.65%12.88%

Risk Profile

Drawdown History

ILMN
JAZZ
GSPC
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Illumina (ILMN) vs. Jazz Pharmaceuticals (JAZZ), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Illumina (ILMN) and Jazz Pharmaceuticals (JAZZ). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Illumina (ILMN) has an aggressive beta of 1.46, indicating higher sensitivity to broad-market moves, while Jazz Pharmaceuticals (JAZZ) is defensive at 0.33 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.

Risk profile metrics for Illumina (ILMN) and Jazz Pharmaceuticals (JAZZ)
MetricILMNJAZZ
Volatility (1Y, Annualized)48.47%38.74%
Beta (5Y)1.460.33
Max Drawdown (5Y)-82.95%-42.03%
Avg. Volume (3M)2.77M878.80K

Risk-Adjusted Performance

Risk-Return Positioning

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ILMN and JAZZ are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Illumina (ILMN) and Jazz Pharmaceuticals (JAZZ)
MetricILMNJAZZ
Sharpe Ratio (1Y)1.562.07
Sortino Ratio (1Y)2.254.14

Profitability

ROE (TTM)

Illumina (ILMN) at 32.39% sits in the top ROE quartile, while Jazz Pharmaceuticals (JAZZ) at 5.05% is closer to the peer norm — stronger capital efficiency for ILMN.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

32.39%

Max
109.18%
ILMN
32.39%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.05%

Max
109.18%
Q3
6.23%
JAZZ
5.05%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Illumina (ILMN) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Illumina (ILMN) at 19.72% converts revenue to bottom-line profit above its industry’s benchmark range, while Jazz Pharmaceuticals (JAZZ) at 4.37% keeps roughly the typical share for its industry.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

19.72%

ILMN
19.72%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.37%

Max
18.05%
Q3
4.78%
JAZZ
4.37%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Illumina (ILMN) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Illumina (ILMN) at 20.02% and Jazz Pharmaceuticals (JAZZ) at 30.17% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

20.02%

Max
83.12%
ILMN
20.02%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

30.17%

Max
83.12%
JAZZ
30.17%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Illumina (ILMN) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Illumina (ILMN) and Jazz Pharmaceuticals (JAZZ)
MetricILMNJAZZ
ROE (TTM)32.39%5.05%
ROA (TTM)8.32%6.92%
Net Margin (TTM)19.72%4.37%
Operating Margin (TTM)20.02%30.17%
Gross Margin (TTM)67.68%91.10%

Growth

Revenue Growth

Jazz Pharmaceuticals (JAZZ) at 4.88% is around its peer norm for revenue growth, while Illumina (ILMN) at -0.66% drops into the bottom quartile, signaling weaker demand or pricing momentum.

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Illumina (ILMN) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: Jazz Pharmaceuticals (JAZZ) reports EPS growth of -167.51%, ranked against its industry; Illumina (ILMN) has no EPS growth figure this period.

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Illumina (ILMN) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Illumina (ILMN) and Jazz Pharmaceuticals (JAZZ)
MetricILMNJAZZ
Revenue Growth (YoY)-0.66%4.88%
Revenue Growth (3Y CAGR)-1.78%5.26%
EPS Growth (YoY)---167.51%
EPS Growth (3Y CAGR)----

Financial Strength

Current Ratio (MRQ)

Illumina (ILMN) at 2.63 keeps current ratio within its industry’s typical mid-range, while Jazz Pharmaceuticals (JAZZ) at 1.82 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for JAZZ.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.63

Max
25.13
Q3
12.13
Median
5.52
ILMN
2.63
Q1
2.47
Min
0.10

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.82

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
JAZZ
1.82
Min
0.10
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Illumina (ILMN) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Both Illumina (ILMN) at 0.74 and Jazz Pharmaceuticals (JAZZ) at 1.35 lean more heavily on debt funding than most peers, landing in the higher-leverage quartile of their industries.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.74

Max
1.42
ILMN
0.74
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.35

Max
1.42
JAZZ
1.35
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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Illumina (ILMN) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for Illumina (ILMN) and Jazz Pharmaceuticals (JAZZ)
MetricILMNJAZZ
Current Ratio (MRQ)2.631.82
Debt / Equity (MRQ)0.741.35
Net Debt / EBITDA0.851.39

Dividends

Dividend Yield (TTM)

Neither Illumina (ILMN) nor Jazz Pharmaceuticals (JAZZ) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ILMN
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

JAZZ
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Illumina (ILMN) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Neither Illumina (ILMN) nor Jazz Pharmaceuticals (JAZZ) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ILMN
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

JAZZ
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Illumina (ILMN) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Illumina (ILMN) and Jazz Pharmaceuticals (JAZZ)
MetricILMNJAZZ
Dividend Yield (TTM)0.00%0.00%
Dividend Payout Ratio (TTM)0.00%0.00%

Valuation

P/E Ratio (TTM)

Illumina (ILMN) at 36.68 is near its industry’s usual P/E ratio, while Jazz Pharmaceuticals (JAZZ) at 69.46 sits in the richer quartile — JAZZ needs stronger growth or earnings quality to justify the premium.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

36.68

Max
85.34
Q3
43.46
ILMN
36.68
Median
26.69
Q1
13.30
Min
0.07

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

69.46

Max
85.34
JAZZ
69.46
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
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Illumina (ILMN) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

On P/S ratio, both Illumina (ILMN) at 7.10 and Jazz Pharmaceuticals (JAZZ) at 3.19 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

7.10

Max
58.18
Q3
25.77
Median
7.30
ILMN
7.10
Q1
3.01
Min
0.01

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.19

Max
58.18
Q3
25.77
Median
7.30
JAZZ
3.19
Q1
3.01
Min
0.01
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Illumina (ILMN) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Jazz Pharmaceuticals (JAZZ) at 3.59 is valued about in line with its industry on P/B ratio, while Illumina (ILMN) at 10.30 carries an above-peer premium to book — ILMN is pricier on assets.

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

10.30

Max
13.53
ILMN
10.30
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59

JAZZ

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.59

Max
13.53
Q3
6.54
JAZZ
3.59
Median
3.25
Q1
1.69
Min
-5.59
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Illumina (ILMN) vs. Jazz Pharmaceuticals (JAZZ): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Illumina (ILMN) and Jazz Pharmaceuticals (JAZZ)
MetricILMNJAZZ
P/E Ratio (TTM)36.6869.46
P/S Ratio (TTM)7.103.19
P/B Ratio (MRQ)10.303.59
Free Cash Flow Yield (TTM)2.67%11.16%