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ICLR vs. TAK: ICON vs. Takeda Pharmaceutical Stock Comparison

How do ICON (ICLR) and Takeda Pharmaceutical (TAK) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

ICON (ICLR) and Takeda Pharmaceutical (TAK) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but ICLR is classified in Life Sciences Tools & Services while TAK is classified in Pharmaceuticals.

ICON (ICLR) trades as ordinary local shares, while Takeda Pharmaceutical (TAK) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.

Company profile comparison for ICON (ICLR) and Takeda Pharmaceutical (TAK)
Profile ItemICLRTAK
NameICON plcTakeda Pharmaceutical Co Ltd ADR
Country/RegionIrelandJapan
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryLife Sciences Tools & ServicesPharmaceuticals
GICS Sub-IndustryLife Sciences Tools & ServicesPharmaceuticals
Market Capitalization15.34 billion USD67.16 billion USD
CurrencyUSDUSD
ExchangeNasdaqNYSE
Listing DateMay 15, 1998January 5, 2010
Security TypeCommon StockADR

Price Performance

Cumulative Growth

ICLR
TAK
GSPC
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ICON (ICLR) vs. Takeda Pharmaceutical (TAK), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for ICON (ICLR) and Takeda Pharmaceutical (TAK). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for ICON (ICLR) and Takeda Pharmaceutical (TAK). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for ICON (ICLR) and Takeda Pharmaceutical (TAK)
MetricICLRTAK
Total Return (1Y)30.55%54.54%
Total Return (3Y, Annualized)-6.05%18.39%
Total Return (5Y, Annualized)-5.40%9.29%

Risk Profile

Drawdown History

ICLR
TAK
GSPC
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ICON (ICLR) vs. Takeda Pharmaceutical (TAK), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for ICON (ICLR) and Takeda Pharmaceutical (TAK). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Takeda Pharmaceutical (TAK) reports a negative beta of -0.01, suggesting inverse market sensitivity over the measurement window. That is uncommon for ordinary equities and can reflect commodity-linked or hedge-like exposure, but it can also come from statistical noise. ICON (ICLR) has a non-negative beta of 1.17.

Risk profile metrics for ICON (ICLR) and Takeda Pharmaceutical (TAK)
MetricICLRTAK
Volatility (1Y, Annualized)68.62%21.45%
Beta (5Y)1.17-0.01
Max Drawdown (5Y)-76.87%-24.83%
Avg. Volume (3M)943.50K2.61M

Risk-Adjusted Performance

Risk-Return Positioning

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ICLR and TAK are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for ICON (ICLR) and Takeda Pharmaceutical (TAK)
MetricICLRTAK
Sharpe Ratio (1Y)0.382.34
Sortino Ratio (1Y)0.523.88

Profitability

ROE (TTM)

Both ICON (ICLR) at 4.70% and Takeda Pharmaceutical (TAK) at 0.56% land near their industries’ usual ROE ranges, so capital efficiency looks broadly in line with peers on both sides.

ICLR

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.70%

Max
109.18%
Q3
6.23%
ICLR
4.70%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.56%

Max
109.18%
Q3
6.23%
TAK
0.56%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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ICON (ICLR) vs. Takeda Pharmaceutical (TAK): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

ICON (ICLR) at 5.26% retains a top-quartile share of revenue as profit, ahead of Takeda Pharmaceutical (TAK) at 0.87%, which keeps about the industry-typical share.

ICLR

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.26%

Max
18.05%
ICLR
5.26%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.87%

Max
18.05%
Q3
4.78%
TAK
0.87%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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ICON (ICLR) vs. Takeda Pharmaceutical (TAK): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Takeda Pharmaceutical (TAK) at 24.55% operates in the top operating margin quartile, ahead of ICON (ICLR) at 10.73%, which runs around its industry’s norm.

ICLR

Pharmaceuticals, Biotechnology & Life Sciences industry group

10.73%

Max
83.12%
Q3
14.77%
ICLR
10.73%
Median
0.00%
Q1
-78.82%
Min
-207.40%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

24.55%

Max
83.12%
TAK
24.55%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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ICON (ICLR) vs. Takeda Pharmaceutical (TAK): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for ICON (ICLR) and Takeda Pharmaceutical (TAK)
MetricICLRTAK
ROE (TTM)4.70%0.56%
ROA (TTM)0.85%3.27%
Net Margin (TTM)5.26%0.87%
Operating Margin (TTM)10.73%24.55%
Gross Margin (TTM)23.44%64.77%

Growth

Revenue Growth

ICON (ICLR) at 0.76% is around its peer norm for revenue growth, while Takeda Pharmaceutical (TAK) at -1.66% drops into the bottom quartile, signaling weaker demand or pricing momentum.

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ICON (ICLR) vs. Takeda Pharmaceutical (TAK): A comparison of their Revenue Growth across different time periods.

EPS Growth

Takeda Pharmaceutical (TAK) at 77.96% sits in the top EPS growth quartile, while ICON (ICLR) at -71.56% is in the bottom quartile, showing a clear gap in earnings momentum.

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ICON (ICLR) vs. Takeda Pharmaceutical (TAK): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for ICON (ICLR) and Takeda Pharmaceutical (TAK)
MetricICLRTAK
Revenue Growth (YoY)0.76%-1.66%
Revenue Growth (3Y CAGR)2.15%3.81%
EPS Growth (YoY)-71.56%77.96%
EPS Growth (3Y CAGR)-23.82%-16.01%

Financial Strength

Current Ratio (MRQ)

Both ICON (ICLR) at 1.32 and Takeda Pharmaceutical (TAK) at 1.15 run current ratio in the tighter-liquidity quartile of industry peers, leaving thinner cushions against current liabilities than typical competitors.

ICLR

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.32

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
ICLR
1.32
Min
0.10

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.15

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
TAK
1.15
Min
0.10
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ICON (ICLR) vs. Takeda Pharmaceutical (TAK): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

ICON (ICLR) at 0.38 carries an industry-typical debt-to-equity mix, while Takeda Pharmaceutical (TAK) at 0.72 uses more debt funding than most peers.

ICLR

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.38

Max
1.42
Q3
0.65
ICLR
0.38
Median
0.15
Q1
0.02
Min
0.00

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.72

Max
1.42
TAK
0.72
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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ICON (ICLR) vs. Takeda Pharmaceutical (TAK): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for ICON (ICLR) and Takeda Pharmaceutical (TAK)
MetricICLRTAK
Current Ratio (MRQ)1.321.15
Debt / Equity (MRQ)0.380.72
Net Debt / EBITDA5.553.61

Dividends

Dividend Yield (TTM)

ICON (ICLR) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Takeda Pharmaceutical (TAK) reports a yield of 953.28%, ranking against industry peers normally.

ICLR

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ICLR
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

953.28%

TAK
953.28%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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ICON (ICLR) vs. Takeda Pharmaceutical (TAK): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Takeda Pharmaceutical (TAK) reports payout ratio above 100% at 426.53%, meaning dividends exceeded current-period earnings; ICON (ICLR) pays no dividend (payout 0.00%).

ICLR

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ICLR
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

426.53%

TAK
426.53%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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ICON (ICLR) vs. Takeda Pharmaceutical (TAK): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for ICON (ICLR) and Takeda Pharmaceutical (TAK)
MetricICLRTAK
Dividend Yield (TTM)0.00%953.28%
Dividend Payout Ratio (TTM)0.00%426.53%

Valuation

P/E Ratio (TTM)

Both look expensive on trailing earnings: ICON (ICLR) at 81.90 sits in the richer P/E ratio quartile, and Takeda Pharmaceutical (TAK) at 300.29 is richer still, above its industry range.

ICLR

Pharmaceuticals, Biotechnology & Life Sciences industry group

81.90

Max
85.34
ICLR
81.90
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

300.29

TAK
300.29
Max
85.34
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
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ICON (ICLR) vs. Takeda Pharmaceutical (TAK): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

Both ICON (ICLR) at 1.86 and Takeda Pharmaceutical (TAK) at 0.01 fetch a relatively low price per dollar of sales, landing in the cheaper P/S ratio quartile of their industries.

ICLR

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.86

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
ICLR
1.86
Min
0.01

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.01

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
TAK
0.01
Min
0.01
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ICON (ICLR) vs. Takeda Pharmaceutical (TAK): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Relative to net asset value, both ICON (ICLR) at 1.68 and Takeda Pharmaceutical (TAK) at 1.43 look inexpensive, sitting in the lower P/B ratio quartile of their industries.

ICLR

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.68

Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
ICLR
1.68
Min
-5.59

TAK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.43

Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
TAK
1.43
Min
-5.59
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ICON (ICLR) vs. Takeda Pharmaceutical (TAK): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for ICON (ICLR) and Takeda Pharmaceutical (TAK)
MetricICLRTAK
P/E Ratio (TTM)81.90300.29
P/S Ratio (TTM)1.860.01
P/B Ratio (MRQ)1.681.43
Free Cash Flow Yield (TTM)3.51%1,014.61%