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HALO vs. RPRX: Halozyme Therapeutics vs. Royalty Pharma Stock Comparison

How do Halozyme Therapeutics (HALO) and Royalty Pharma (RPRX) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Halozyme Therapeutics (HALO) and Royalty Pharma (RPRX) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but HALO is classified in Biotechnology while RPRX is classified in Pharmaceuticals.

Halozyme Therapeutics (HALO) has more than two decades of public-market history since March 16, 2004, whereas Royalty Pharma (RPRX) listed on June 16, 2020 and has a much shorter record to draw on.

Company profile comparison for Halozyme Therapeutics (HALO) and Royalty Pharma (RPRX)
Profile ItemHALORPRX
NameHalozyme Therapeutics Inc.Royalty Pharma plc Class A Ordinary Shares
Country/RegionUnited StatesUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnologyPharmaceuticals
GICS Sub-IndustryBiotechnologyPharmaceuticals
Market Capitalization11.81 billion USD38.70 billion USD
CurrencyUSDUSD
ExchangeNasdaqNasdaq
Listing DateMarch 16, 2004June 16, 2020
Security TypeCommon StockCommon Stock

Price Performance

Cumulative Growth

HALO
RPRX
GSPC
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Halozyme Therapeutics (HALO) vs. Royalty Pharma (RPRX), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Halozyme Therapeutics (HALO) and Royalty Pharma (RPRX). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Halozyme Therapeutics (HALO) and Royalty Pharma (RPRX). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Halozyme Therapeutics (HALO) and Royalty Pharma (RPRX)
MetricHALORPRX
Total Return (1Y)50.94%81.08%
Total Return (3Y, Annualized)41.08%39.21%
Total Return (5Y, Annualized)21.68%14.22%

Risk Profile

Drawdown History

HALO
RPRX
GSPC
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Halozyme Therapeutics (HALO) vs. Royalty Pharma (RPRX), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Halozyme Therapeutics (HALO) and Royalty Pharma (RPRX). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Halozyme Therapeutics (HALO) and Royalty Pharma (RPRX)
MetricHALORPRX
Volatility (1Y, Annualized)41.19%22.05%
Beta (5Y)0.960.36
Max Drawdown (5Y)-49.06%-41.98%
Avg. Volume (3M)2.29M3.10M

Risk-Adjusted Performance

Risk-Return Positioning

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HALO and RPRX are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Halozyme Therapeutics (HALO) and Royalty Pharma (RPRX)
MetricHALORPRX
Sharpe Ratio (1Y)1.133.48
Sortino Ratio (1Y)1.785.72

Profitability

ROE (TTM)

Both companies show strong equity returns, but Halozyme Therapeutics (HALO) at 216.38% is the standout with ROE above its industry range; Royalty Pharma (RPRX) at 12.09% also sits in the top quartile.

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

216.38%

HALO
216.38%
Max
109.18%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

12.09%

Max
109.18%
RPRX
12.09%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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Halozyme Therapeutics (HALO) vs. Royalty Pharma (RPRX): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Both Halozyme Therapeutics (HALO) at 26.93% and Royalty Pharma (RPRX) at 25.70% keep an unusually large share of revenue as bottom-line profit — each net margin clears its industry’s benchmark range.

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

26.93%

HALO
26.93%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

25.70%

RPRX
25.70%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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Halozyme Therapeutics (HALO) vs. Royalty Pharma (RPRX): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both Halozyme Therapeutics (HALO) at 59.84% and Royalty Pharma (RPRX) at 81.32% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

59.84%

Max
83.12%
HALO
59.84%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

81.32%

Max
83.12%
RPRX
81.32%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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Halozyme Therapeutics (HALO) vs. Royalty Pharma (RPRX): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Halozyme Therapeutics (HALO) and Royalty Pharma (RPRX)
MetricHALORPRX
ROE (TTM)216.38%12.09%
ROA (TTM)22.42%5.43%
Net Margin (TTM)26.93%25.70%
Operating Margin (TTM)59.84%81.32%
Gross Margin (TTM)77.74%99.79%

Growth

Revenue Growth

Both Halozyme Therapeutics (HALO) at 37.55% and Royalty Pharma (RPRX) at 5.06% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

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Halozyme Therapeutics (HALO) vs. Royalty Pharma (RPRX): A comparison of their Revenue Growth across different time periods.

EPS Growth

Both Halozyme Therapeutics (HALO) at -25.36% and Royalty Pharma (RPRX) at 23.09% land near their industries' usual EPS growth ranges, so bottom-line momentum looks broadly in line with peers on both sides.

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Halozyme Therapeutics (HALO) vs. Royalty Pharma (RPRX): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Halozyme Therapeutics (HALO) and Royalty Pharma (RPRX)
MetricHALORPRX
Revenue Growth (YoY)37.55%5.06%
Revenue Growth (3Y CAGR)28.38%2.06%
EPS Growth (YoY)-25.36%23.09%
EPS Growth (3Y CAGR)21.14%161.10%

Financial Strength

Current Ratio (MRQ)

Halozyme Therapeutics (HALO) at 3.88 keeps current ratio within its industry’s typical mid-range, while Royalty Pharma (RPRX) at 1.29 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for RPRX.

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.88

Max
25.13
Q3
12.13
Median
5.52
HALO
3.88
Q1
2.47
Min
0.10

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.29

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
RPRX
1.29
Min
0.10
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Halozyme Therapeutics (HALO) vs. Royalty Pharma (RPRX): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Only one side’s leverage can be read here: Royalty Pharma (RPRX) carries debt-to-equity ratio of 0.88 against its industry range, while Halozyme Therapeutics (HALO) reports no figure this period.

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

--

Max
1.42
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
HALO
--

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.88

Max
1.42
RPRX
0.88
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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Halozyme Therapeutics (HALO) vs. Royalty Pharma (RPRX): HALO does not report debt-to-equity ratio, so it has no value marker; RPRX is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

Financial Strength Metrics

Financial strength metrics for Halozyme Therapeutics (HALO) and Royalty Pharma (RPRX)
MetricHALORPRX
Current Ratio (MRQ)3.881.29
Debt / Equity (MRQ)--0.88
Net Debt / EBITDA1.904.76

Dividends

Dividend Yield (TTM)

Halozyme Therapeutics (HALO) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Royalty Pharma (RPRX) reports a yield of 1.37%, ranking against industry peers normally.

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

HALO
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.37%

RPRX
1.37%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Halozyme Therapeutics (HALO) vs. Royalty Pharma (RPRX): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Halozyme Therapeutics (HALO) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile Royalty Pharma (RPRX) reports a payout of 60.46%, ranking against industry peers normally.

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

HALO
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

60.46%

RPRX
60.46%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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Halozyme Therapeutics (HALO) vs. Royalty Pharma (RPRX): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Halozyme Therapeutics (HALO) and Royalty Pharma (RPRX)
MetricHALORPRX
Dividend Yield (TTM)0.00%1.37%
Dividend Payout Ratio (TTM)0.00%60.46%

Valuation

P/E Ratio (TTM)

Halozyme Therapeutics (HALO) at 25.91 is near its industry’s usual P/E ratio, while Royalty Pharma (RPRX) at 43.99 sits in the richer quartile — RPRX needs stronger growth or earnings quality to justify the premium.

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

25.91

Max
85.34
Q3
43.46
Median
26.69
HALO
25.91
Q1
13.30
Min
0.07

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

43.99

Max
85.34
RPRX
43.99
Q3
43.46
Median
26.69
Q1
13.30
Min
0.07
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Halozyme Therapeutics (HALO) vs. Royalty Pharma (RPRX): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

On P/S ratio, both Halozyme Therapeutics (HALO) at 6.55 and Royalty Pharma (RPRX) at 14.79 are priced roughly in line with their industries — neither looks cheap nor rich on a sales basis.

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.55

Max
58.18
Q3
25.77
Median
7.30
HALO
6.55
Q1
3.01
Min
0.01

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

14.79

Max
58.18
Q3
25.77
RPRX
14.79
Median
7.30
Q1
3.01
Min
0.01
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Halozyme Therapeutics (HALO) vs. Royalty Pharma (RPRX): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Halozyme Therapeutics (HALO) reports a negative P/B ratio of -213.67, meaning negative book equity — the multiple itself is not meaningful for valuation. Meanwhile Royalty Pharma (RPRX) reports 4.39, ranking against industry peers normally.

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

-213.67

Max
13.53
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
HALO
-213.67

RPRX

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.39

Max
13.53
Q3
6.54
RPRX
4.39
Median
3.25
Q1
1.69
Min
-5.59
Loading chart…
Halozyme Therapeutics (HALO) vs. Royalty Pharma (RPRX): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Halozyme Therapeutics (HALO) and Royalty Pharma (RPRX)
MetricHALORPRX
P/E Ratio (TTM)25.9143.99
P/S Ratio (TTM)6.5514.79
P/B Ratio (MRQ)-213.674.39
Free Cash Flow Yield (TTM)3.48%-1.16%