HALO vs. IQV: Halozyme Therapeutics vs. IQVIA Stock Comparison

November 11, 2026

How do Halozyme Therapeutics (HALO) and IQVIA (IQV) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

Halozyme Therapeutics (HALO) and IQVIA (IQV) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but HALO is classified in Biotechnology while IQV is classified in Life Sciences Tools & Services.

Company profile comparison for Halozyme Therapeutics (HALO) and IQVIA (IQV)
Profile Item	HALO	IQV
Name	Halozyme Therapeutics Inc.	IQVIA Holdings Inc.
Country/Region	United States	United States
GICS Sector	Health Care	Health Care
GICS Industry Group	Pharmaceuticals, Biotechnology & Life Sciences	Pharmaceuticals, Biotechnology & Life Sciences
GICS Industry	Biotechnology	Life Sciences Tools & Services
GICS Sub-Industry	Biotechnology	Life Sciences Tools & Services
Market Capitalization	11.81 billion USD	44.80 billion USD
Currency	USD	USD
Exchange	Nasdaq	NYSE
Listing Date	March 16, 2004	May 9, 2013
Security Type	Common Stock	Common Stock

Price Performance

Cumulative Growth

HALO

IQV

GSPC

Halozyme Therapeutics (HALO) vs. IQVIA (IQV), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for Halozyme Therapeutics (HALO) and IQVIA (IQV). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for Halozyme Therapeutics (HALO) and IQVIA (IQV). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for Halozyme Therapeutics (HALO) and IQVIA (IQV)
Metric	HALO	IQV
Total Return (1Y)	50.94%	32.11%
Total Return (3Y, Annualized)	41.08%	13.15%
Total Return (5Y, Annualized)	21.68%	2.00%

Risk Profile

Drawdown History

HALO

IQV

GSPC

Halozyme Therapeutics (HALO) vs. IQVIA (IQV), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for Halozyme Therapeutics (HALO) and IQVIA (IQV). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for Halozyme Therapeutics (HALO) and IQVIA (IQV)
Metric	HALO	IQV
Volatility (1Y, Annualized)	41.19%	40.77%
Beta (5Y)	0.96	1.14
Max Drawdown (5Y)	-49.06%	-51.52%
Avg. Volume (3M)	2.29M	1.40M

Risk-Adjusted Performance

Risk-Return Positioning

HALO and IQV are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for Halozyme Therapeutics (HALO) and IQVIA (IQV)
Metric	HALO	IQV
Sharpe Ratio (1Y)	1.13	0.68
Sortino Ratio (1Y)	1.78	1.03

Profitability

ROE (TTM)

Both companies show strong equity returns, but Halozyme Therapeutics (HALO) at 216.38% is the standout with ROE above its industry range; IQVIA (IQV) at 21.39% also sits in the top quartile.

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

216.38%

HALO: 216.38%
Max: 109.18%
Q3: 6.23%
Median: -26.66%
Q1: -64.05%
Min: -167.77%

IQV

Pharmaceuticals, Biotechnology & Life Sciences industry group

21.39%

Max: 109.18%
IQV: 21.39%
Q3: 6.23%
Median: -26.66%
Q1: -64.05%
Min: -167.77%

Halozyme Therapeutics (HALO) vs. IQVIA (IQV): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Halozyme Therapeutics (HALO) at 26.93% keeps the most of each sales dollar — above its industry’s net margin range — and IQVIA (IQV) at 8.05% also retains a top-quartile share.

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

26.93%

HALO: 26.93%
Max: 18.05%
Q3: 4.78%
Median: 0.00%
Q1: -4.14%
Min: -17.05%

IQV

Pharmaceuticals, Biotechnology & Life Sciences industry group

8.05%

Max: 18.05%
IQV: 8.05%
Q3: 4.78%
Median: 0.00%
Q1: -4.14%
Min: -17.05%

Halozyme Therapeutics (HALO) vs. IQVIA (IQV): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Halozyme Therapeutics (HALO) at 59.84% operates in the top operating margin quartile, ahead of IQVIA (IQV) at 13.73%, which runs around its industry’s norm.

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

59.84%

Max: 83.12%
HALO: 59.84%
Q3: 14.77%
Median: 0.00%
Q1: -78.82%
Min: -207.40%

IQV

Pharmaceuticals, Biotechnology & Life Sciences industry group

13.73%

Max: 83.12%
Q3: 14.77%
IQV: 13.73%
Median: 0.00%
Q1: -78.82%
Min: -207.40%

Halozyme Therapeutics (HALO) vs. IQVIA (IQV): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for Halozyme Therapeutics (HALO) and IQVIA (IQV)
Metric	HALO	IQV
ROE (TTM)	216.38%	21.39%
ROA (TTM)	22.42%	5.08%
Net Margin (TTM)	26.93%	8.05%
Operating Margin (TTM)	59.84%	13.73%
Gross Margin (TTM)	77.74%	33.07%

Growth

Revenue Growth

Both Halozyme Therapeutics (HALO) at 37.55% and IQVIA (IQV) at 5.87% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

Halozyme Therapeutics (HALO) vs. IQVIA (IQV): A comparison of their Revenue Growth across different time periods.

EPS Growth

Both Halozyme Therapeutics (HALO) at -25.36% and IQVIA (IQV) at 4.67% land near their industries' usual EPS growth ranges, so bottom-line momentum looks broadly in line with peers on both sides.

Halozyme Therapeutics (HALO) vs. IQVIA (IQV): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for Halozyme Therapeutics (HALO) and IQVIA (IQV)
Metric	HALO	IQV
Revenue Growth (YoY)	37.55%	5.87%
Revenue Growth (3Y CAGR)	28.38%	4.21%
EPS Growth (YoY)	-25.36%	4.67%
EPS Growth (3Y CAGR)	21.14%	11.08%

Financial Strength

Current Ratio (MRQ)

Halozyme Therapeutics (HALO) at 3.88 keeps current ratio within its industry’s typical mid-range, while IQVIA (IQV) at 0.83 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for IQV.

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.88

Max: 25.13
Q3: 12.13
Median: 5.52
HALO: 3.88
Q1: 2.47
Min: 0.10

IQV

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.83

Max: 25.13
Q3: 12.13
Median: 5.52
Q1: 2.47
IQV: 0.83
Min: 0.10

Halozyme Therapeutics (HALO) vs. IQVIA (IQV): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Only one side’s leverage can be read here: IQVIA (IQV) carries debt-to-equity ratio of 2.40 against its industry range, while Halozyme Therapeutics (HALO) reports no figure this period.

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

Max: 1.42
Q3: 0.65
Median: 0.15
Q1: 0.02
Min: 0.00
HALO: --

IQV

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.40

IQV: 2.40
Max: 1.42
Q3: 0.65
Median: 0.15
Q1: 0.02
Min: 0.00

Halozyme Therapeutics (HALO) vs. IQVIA (IQV): HALO does not report debt-to-equity ratio, so it has no value marker; IQV is benchmarked against the Pharmaceuticals, Biotechnology & Life Sciences industry group.

Financial Strength Metrics

Financial strength metrics for Halozyme Therapeutics (HALO) and IQVIA (IQV)
Metric	HALO	IQV
Current Ratio (MRQ)	3.88	0.83
Debt / Equity (MRQ)	--	2.40
Net Debt / EBITDA	1.90	4.46

Dividends

Dividend Yield (TTM)

Neither Halozyme Therapeutics (HALO) nor IQVIA (IQV) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

HALO: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

IQV

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

IQV: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Halozyme Therapeutics (HALO) vs. IQVIA (IQV): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Neither Halozyme Therapeutics (HALO) nor IQVIA (IQV) pays a dividend this period — they may reinvest, use buybacks, or simply not return cash through dividends.

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

HALO: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

IQV

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

IQV: 0.00%
Max: 0.00%
Q3: 0.00%
Median: 0.00%
Q1: 0.00%
Min: 0.00%

Halozyme Therapeutics (HALO) vs. IQVIA (IQV): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for Halozyme Therapeutics (HALO) and IQVIA (IQV)
Metric	HALO	IQV
Dividend Yield (TTM)	0.00%	0.00%
Dividend Payout Ratio (TTM)	0.00%	0.00%

Valuation

P/E Ratio (TTM)

Both Halozyme Therapeutics (HALO) at 25.91 and IQVIA (IQV) at 33.07 land around their industries’ usual P/E ratio levels — neither is getting a clear earnings-multiple discount or premium versus peers.

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

25.91

Max: 85.34
Q3: 43.46
Median: 26.69
HALO: 25.91
Q1: 13.30
Min: 0.07

IQV

Pharmaceuticals, Biotechnology & Life Sciences industry group

33.07

Max: 85.34
Q3: 43.46
IQV: 33.07
Median: 26.69
Q1: 13.30
Min: 0.07

Halozyme Therapeutics (HALO) vs. IQVIA (IQV): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

IQVIA (IQV) at 2.59 sits in the cheaper P/S ratio quartile while Halozyme Therapeutics (HALO) at 6.55 prices around its industry’s middle — IQV costs less per dollar of sales, though read it alongside growth and margins.

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.55

Max: 58.18
Q3: 25.77
Median: 7.30
HALO: 6.55
Q1: 3.01
Min: 0.01

IQV

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.59

Max: 58.18
Q3: 25.77
Median: 7.30
Q1: 3.01
IQV: 2.59
Min: 0.01

Halozyme Therapeutics (HALO) vs. IQVIA (IQV): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

Halozyme Therapeutics (HALO) reports a negative P/B ratio of -213.67, meaning negative book equity — the multiple itself is not meaningful for valuation. Meanwhile IQVIA (IQV) reports 6.73, ranking against industry peers normally.

HALO

Pharmaceuticals, Biotechnology & Life Sciences industry group

-213.67

Max: 13.53
Q3: 6.54
Median: 3.25
Q1: 1.69
Min: -5.59
HALO: -213.67

IQV

Pharmaceuticals, Biotechnology & Life Sciences industry group

6.73

Max: 13.53
IQV: 6.73
Q3: 6.54
Median: 3.25
Q1: 1.69
Min: -5.59

Halozyme Therapeutics (HALO) vs. IQVIA (IQV): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for Halozyme Therapeutics (HALO) and IQVIA (IQV)
Metric	HALO	IQV
P/E Ratio (TTM)	25.91	33.07
P/S Ratio (TTM)	6.55	2.59
P/B Ratio (MRQ)	-213.67	6.73
Free Cash Flow Yield (TTM)	3.48%	4.72%