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GSK vs. REGN: GSK vs. Regeneron Pharmaceuticals Stock Comparison

How do GSK (GSK) and Regeneron Pharmaceuticals (REGN) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

GSK (GSK) and Regeneron Pharmaceuticals (REGN) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but GSK is classified in Pharmaceuticals while REGN is classified in Biotechnology.

Regeneron Pharmaceuticals (REGN) trades as ordinary local shares, while GSK (GSK) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.

Company profile comparison for GSK (GSK) and Regeneron Pharmaceuticals (REGN)
Profile ItemGSKREGN
NameGSK plc ADRRegeneron Pharmaceuticals, Inc.
Country/RegionUnited KingdomUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryPharmaceuticalsBiotechnology
GICS Sub-IndustryPharmaceuticalsBiotechnology
Market Capitalization100.88 billion USD93.55 billion USD
CurrencyUSDUSD
ExchangeNYSENasdaq
Listing DateMarch 28, 1980April 2, 1991
Security TypeADRCommon Stock

Price Performance

Cumulative Growth

GSK
REGN
GSPC
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GSK (GSK) vs. Regeneron Pharmaceuticals (REGN), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for GSK (GSK) and Regeneron Pharmaceuticals (REGN). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for GSK (GSK) and Regeneron Pharmaceuticals (REGN). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for GSK (GSK) and Regeneron Pharmaceuticals (REGN)
MetricGSKREGN
Total Return (1Y)13.73%40.87%
Total Return (3Y, Annualized)18.65%5.15%
Total Return (5Y, Annualized)7.97%8.58%

Risk Profile

Drawdown History

GSK
REGN
GSPC
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GSK (GSK) vs. Regeneron Pharmaceuticals (REGN), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for GSK (GSK) and Regeneron Pharmaceuticals (REGN). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Risk profile metrics for GSK (GSK) and Regeneron Pharmaceuticals (REGN)
MetricGSKREGN
Volatility (1Y, Annualized)26.25%34.08%
Beta (5Y)0.310.10
Max Drawdown (5Y)-37.63%-59.69%
Avg. Volume (3M)4.05M772.95K

Risk-Adjusted Performance

Risk-Return Positioning

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GSK and REGN are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for GSK (GSK) and Regeneron Pharmaceuticals (REGN)
MetricGSKREGN
Sharpe Ratio (1Y)0.361.07
Sortino Ratio (1Y)0.561.70

Profitability

ROE (TTM)

Both GSK (GSK) at 28.27% and Regeneron Pharmaceuticals (REGN) at 14.95% sit in the top peer quartile for ROE, suggesting each generates more profit from shareholders’ equity than typical industry peers.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

28.27%

Max
109.18%
GSK
28.27%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

REGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

14.95%

Max
109.18%
REGN
14.95%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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GSK (GSK) vs. Regeneron Pharmaceuticals (REGN): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Regeneron Pharmaceuticals (REGN) at 28.51% keeps the most of each sales dollar — above its industry’s net margin range — and GSK (GSK) at 12.97% also retains a top-quartile share.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

12.97%

Max
18.05%
GSK
12.97%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

REGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

28.51%

REGN
28.51%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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GSK (GSK) vs. Regeneron Pharmaceuticals (REGN): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both GSK (GSK) at 32.14% and Regeneron Pharmaceuticals (REGN) at 40.46% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

32.14%

Max
83.12%
GSK
32.14%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

REGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

40.46%

Max
83.12%
REGN
40.46%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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GSK (GSK) vs. Regeneron Pharmaceuticals (REGN): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for GSK (GSK) and Regeneron Pharmaceuticals (REGN)
MetricGSKREGN
ROE (TTM)28.27%14.95%
ROA (TTM)9.24%7.59%
Net Margin (TTM)12.97%28.51%
Operating Margin (TTM)32.14%40.46%
Gross Margin (TTM)73.79%46.73%

Growth

Revenue Growth

Both GSK (GSK) at 4.11% and Regeneron Pharmaceuticals (REGN) at 0.99% land near their industries' usual revenue growth ranges, so top-line momentum looks broadly in line with peers on both sides.

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GSK (GSK) vs. Regeneron Pharmaceuticals (REGN): A comparison of their Revenue Growth across different time periods.

EPS Growth

GSK (GSK) at 123.15% sits in the top EPS growth quartile, while Regeneron Pharmaceuticals (REGN) at 8.19% is closer to the peer norm — faster per-share earnings growth for GSK.

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GSK (GSK) vs. Regeneron Pharmaceuticals (REGN): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for GSK (GSK) and Regeneron Pharmaceuticals (REGN)
MetricGSKREGN
Revenue Growth (YoY)4.11%0.99%
Revenue Growth (3Y CAGR)3.66%5.62%
EPS Growth (YoY)123.15%8.19%
EPS Growth (3Y CAGR)-27.63%2.77%

Financial Strength

Current Ratio (MRQ)

Regeneron Pharmaceuticals (REGN) at 3.35 keeps current ratio within its industry’s typical mid-range, while GSK (GSK) at 0.86 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for GSK.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.86

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
GSK
0.86
Min
0.10

REGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.35

Max
25.13
Q3
12.13
Median
5.52
REGN
3.35
Q1
2.47
Min
0.10
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GSK (GSK) vs. Regeneron Pharmaceuticals (REGN): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Regeneron Pharmaceuticals (REGN) at 0.08 carries an industry-typical debt-to-equity mix, while GSK (GSK) at 1.30 uses more debt funding than most peers.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.30

Max
1.42
GSK
1.30
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

REGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.08

Max
1.42
Q3
0.65
Median
0.15
REGN
0.08
Q1
0.02
Min
0.00
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GSK (GSK) vs. Regeneron Pharmaceuticals (REGN): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for GSK (GSK) and Regeneron Pharmaceuticals (REGN)
MetricGSKREGN
Current Ratio (MRQ)0.863.35
Debt / Equity (MRQ)1.300.08
Net Debt / EBITDA1.88-1.17

Dividends

Dividend Yield (TTM)

Both GSK (GSK) at 1.57% and Regeneron Pharmaceuticals (REGN) at 0.41% yield above their industries’ entire benchmark ranges — high enough that dividend safety, not income, becomes the first question.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.57%

GSK
1.57%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

REGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.41%

REGN
0.41%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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GSK (GSK) vs. Regeneron Pharmaceuticals (REGN): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Both GSK (GSK) at 63.33% and Regeneron Pharmaceuticals (REGN) at 8.18% pay out more of their earnings than any of their industry peers — the thinnest cover in their groups, so dividend headroom deserves attention.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

63.33%

GSK
63.33%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

REGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

8.18%

REGN
8.18%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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GSK (GSK) vs. Regeneron Pharmaceuticals (REGN): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for GSK (GSK) and Regeneron Pharmaceuticals (REGN)
MetricGSKREGN
Dividend Yield (TTM)1.57%0.41%
Dividend Payout Ratio (TTM)63.33%8.18%

Valuation

P/E Ratio (TTM)

Both GSK (GSK) at 17.54 and Regeneron Pharmaceuticals (REGN) at 19.99 land around their industries’ usual P/E ratio levels — neither is getting a clear earnings-multiple discount or premium versus peers.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

17.54

Max
85.34
Q3
43.46
Median
26.69
GSK
17.54
Q1
13.30
Min
0.07

REGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

19.99

Max
85.34
Q3
43.46
Median
26.69
REGN
19.99
Q1
13.30
Min
0.07
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GSK (GSK) vs. Regeneron Pharmaceuticals (REGN): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

GSK (GSK) at 3.01 sits in the cheaper P/S ratio quartile while Regeneron Pharmaceuticals (REGN) at 5.54 prices around its industry’s middle — GSK costs less per dollar of sales, though read it alongside growth and margins.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.01

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
GSK
3.01
Min
0.01

REGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

5.54

Max
58.18
Q3
25.77
Median
7.30
REGN
5.54
Q1
3.01
Min
0.01
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GSK (GSK) vs. Regeneron Pharmaceuticals (REGN): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

On P/B ratio, both GSK (GSK) at 4.02 and Regeneron Pharmaceuticals (REGN) at 2.71 are valued close to their industries’ norm against book — neither stands out from peers.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.02

Max
13.53
Q3
6.54
GSK
4.02
Median
3.25
Q1
1.69
Min
-5.59

REGN

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.71

Max
13.53
Q3
6.54
Median
3.25
REGN
2.71
Q1
1.69
Min
-5.59
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GSK (GSK) vs. Regeneron Pharmaceuticals (REGN): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for GSK (GSK) and Regeneron Pharmaceuticals (REGN)
MetricGSKREGN
P/E Ratio (TTM)17.5419.99
P/S Ratio (TTM)3.015.54
P/B Ratio (MRQ)4.022.71
Free Cash Flow Yield (TTM)5.28%2.76%