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GSK vs. ILMN: GSK vs. Illumina Stock Comparison

How do GSK (GSK) and Illumina (ILMN) stack up? This page sets them side by side across company profile, performance and risk, profitability, growth, financial strength, dividends, and valuation, with selected fundamentals also measured against each stock's industry-group peers.

Company Profile

GSK (GSK) and Illumina (ILMN) both fall under the Pharmaceuticals, Biotechnology & Life Sciences industry group, but GSK is classified in Pharmaceuticals while ILMN is classified in Life Sciences Tools & Services.

Illumina (ILMN) trades as ordinary local shares, while GSK (GSK) trades as an ADR — compare with FX exposure, depositary-program fees, and dividend-withholding-tax differences in mind.

Company profile comparison for GSK (GSK) and Illumina (ILMN)
Profile ItemGSKILMN
NameGSK plc ADRIllumina Inc.
Country/RegionUnited KingdomUnited States
GICS SectorHealth CareHealth Care
GICS Industry GroupPharmaceuticals, Biotechnology & Life SciencesPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryPharmaceuticalsLife Sciences Tools & Services
GICS Sub-IndustryPharmaceuticalsLife Sciences Tools & Services
Market Capitalization100.88 billion USD32.23 billion USD
CurrencyUSDUSD
ExchangeNYSENasdaq
Listing DateMarch 28, 1980July 28, 2000
Security TypeADRCommon Stock

Price Performance

Cumulative Growth

GSK
ILMN
GSPC
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GSK (GSK) vs. Illumina (ILMN), with S&P 500 (GSPC) for reference: Growth of a $10,000 investment over the past five years. Adjusted for dividends and splits.

Trailing Returns

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Trailing total returns for GSK (GSK) and Illumina (ILMN). Returns over one year are annualized.

Calendar-Year Returns

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Calendar-year total returns for GSK (GSK) and Illumina (ILMN). Each bar is that year's total return, measured year-end to year-end.

Performance Metrics

Price performance metrics for GSK (GSK) and Illumina (ILMN)
MetricGSKILMN
Total Return (1Y)13.73%79.70%
Total Return (3Y, Annualized)18.65%28.16%
Total Return (5Y, Annualized)7.97%-10.65%

Risk Profile

Drawdown History

GSK
ILMN
GSPC
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GSK (GSK) vs. Illumina (ILMN), with S&P 500 (GSPC) for reference: Drawdown from the running peak over the past five years. Each line shows the decline from its prior peak; 0% marks a new high.

Return Distribution

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Distribution of monthly total returns for GSK (GSK) and Illumina (ILMN). Each bar is the share of months whose return fell in that 5% bucket.

Risk Metrics

Illumina (ILMN) has an aggressive beta of 1.46, indicating higher sensitivity to broad-market moves, while GSK (GSK) is defensive at 0.31 and tends to be less market-sensitive — they sit on opposite ends of the beta spectrum.

Risk profile metrics for GSK (GSK) and Illumina (ILMN)
MetricGSKILMN
Volatility (1Y, Annualized)26.25%48.47%
Beta (5Y)0.311.46
Max Drawdown (5Y)-37.63%-82.95%
Avg. Volume (3M)4.05M2.77M

Risk-Adjusted Performance

Risk-Return Positioning

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GSK and ILMN are plotted by 1-year volatility (risk) and 1-year return. The dashed Capital Allocation Line runs from the risk-free rate through the shared industry median.

Risk-Adjusted Metrics

Risk-adjusted metrics for GSK (GSK) and Illumina (ILMN)
MetricGSKILMN
Sharpe Ratio (1Y)0.361.56
Sortino Ratio (1Y)0.562.25

Profitability

ROE (TTM)

Both GSK (GSK) at 28.27% and Illumina (ILMN) at 32.39% sit in the top peer quartile for ROE, suggesting each generates more profit from shareholders’ equity than typical industry peers.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

28.27%

Max
109.18%
GSK
28.27%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

32.39%

Max
109.18%
ILMN
32.39%
Q3
6.23%
Median
-26.66%
Q1
-64.05%
Min
-167.77%
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GSK (GSK) vs. Illumina (ILMN): A comparison of their ROE against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Net Margin (TTM)

Illumina (ILMN) at 19.72% keeps the most of each sales dollar — above its industry’s net margin range — and GSK (GSK) at 12.97% also retains a top-quartile share.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

12.97%

Max
18.05%
GSK
12.97%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

19.72%

ILMN
19.72%
Max
18.05%
Q3
4.78%
Median
0.00%
Q1
-4.14%
Min
-17.05%
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GSK (GSK) vs. Illumina (ILMN): A comparison of their net margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Operating Margin (TTM)

Both GSK (GSK) at 32.14% and Illumina (ILMN) at 20.02% convert sales into operating profit at a top-quartile rate, pointing to tighter cost discipline before financing and tax.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

32.14%

Max
83.12%
GSK
32.14%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

20.02%

Max
83.12%
ILMN
20.02%
Q3
14.77%
Median
0.00%
Q1
-78.82%
Min
-207.40%
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GSK (GSK) vs. Illumina (ILMN): A comparison of their operating margin against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Profitability Metrics

Profitability metrics for GSK (GSK) and Illumina (ILMN)
MetricGSKILMN
ROE (TTM)28.27%32.39%
ROA (TTM)9.24%8.32%
Net Margin (TTM)12.97%19.72%
Operating Margin (TTM)32.14%20.02%
Gross Margin (TTM)73.79%67.68%

Growth

Revenue Growth

GSK (GSK) at 4.11% is around its peer norm for revenue growth, while Illumina (ILMN) at -0.66% drops into the bottom quartile, signaling weaker demand or pricing momentum.

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GSK (GSK) vs. Illumina (ILMN): A comparison of their Revenue Growth across different time periods.

EPS Growth

Only one side can be read here: GSK (GSK) reports EPS growth of 123.15%, ranked against its industry; Illumina (ILMN) has no EPS growth figure this period.

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GSK (GSK) vs. Illumina (ILMN): A comparison of their EPS Growth across different time periods.

Growth Metrics

Growth metrics for GSK (GSK) and Illumina (ILMN)
MetricGSKILMN
Revenue Growth (YoY)4.11%-0.66%
Revenue Growth (3Y CAGR)3.66%-1.78%
EPS Growth (YoY)123.15%--
EPS Growth (3Y CAGR)-27.63%--

Financial Strength

Current Ratio (MRQ)

Illumina (ILMN) at 2.63 keeps current ratio within its industry’s typical mid-range, while GSK (GSK) at 0.86 runs in the tighter-liquidity quartile — a thinner cushion against current liabilities for GSK.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.86

Max
25.13
Q3
12.13
Median
5.52
Q1
2.47
GSK
0.86
Min
0.10

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

2.63

Max
25.13
Q3
12.13
Median
5.52
ILMN
2.63
Q1
2.47
Min
0.10
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GSK (GSK) vs. Illumina (ILMN): A comparison of their current ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Debt / Equity (MRQ)

Both GSK (GSK) at 1.30 and Illumina (ILMN) at 0.74 lean more heavily on debt funding than most peers, landing in the higher-leverage quartile of their industries.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.30

Max
1.42
GSK
1.30
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.74

Max
1.42
ILMN
0.74
Q3
0.65
Median
0.15
Q1
0.02
Min
0.00
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GSK (GSK) vs. Illumina (ILMN): A comparison of their debt-to-equity ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Financial Strength Metrics

Financial strength metrics for GSK (GSK) and Illumina (ILMN)
MetricGSKILMN
Current Ratio (MRQ)0.862.63
Debt / Equity (MRQ)1.300.74
Net Debt / EBITDA1.880.85

Dividends

Dividend Yield (TTM)

Illumina (ILMN) pays no dividend (yield 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile GSK (GSK) reports a yield of 1.57%, ranking against industry peers normally.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

1.57%

GSK
1.57%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ILMN
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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GSK (GSK) vs. Illumina (ILMN): A comparison of their dividend yield against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Payout Ratio (TTM)

Illumina (ILMN) pays no dividend (payout 0.00%) — it may be reinvesting, using buybacks, or simply not returning cash through dividends. Meanwhile GSK (GSK) reports a payout of 63.33%, ranking against industry peers normally.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

63.33%

GSK
63.33%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

0.00%

ILMN
0.00%
Max
0.00%
Q3
0.00%
Median
0.00%
Q1
0.00%
Min
0.00%
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GSK (GSK) vs. Illumina (ILMN): A comparison of their payout ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Dividend Metrics

Dividend metrics for GSK (GSK) and Illumina (ILMN)
MetricGSKILMN
Dividend Yield (TTM)1.57%0.00%
Dividend Payout Ratio (TTM)63.33%0.00%

Valuation

P/E Ratio (TTM)

Both GSK (GSK) at 17.54 and Illumina (ILMN) at 36.68 land around their industries’ usual P/E ratio levels — neither is getting a clear earnings-multiple discount or premium versus peers.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

17.54

Max
85.34
Q3
43.46
Median
26.69
GSK
17.54
Q1
13.30
Min
0.07

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

36.68

Max
85.34
Q3
43.46
ILMN
36.68
Median
26.69
Q1
13.30
Min
0.07
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GSK (GSK) vs. Illumina (ILMN): A comparison of their P/E ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/S Ratio (TTM)

GSK (GSK) at 3.01 sits in the cheaper P/S ratio quartile while Illumina (ILMN) at 7.10 prices around its industry’s middle — GSK costs less per dollar of sales, though read it alongside growth and margins.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

3.01

Max
58.18
Q3
25.77
Median
7.30
Q1
3.01
GSK
3.01
Min
0.01

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

7.10

Max
58.18
Q3
25.77
Median
7.30
ILMN
7.10
Q1
3.01
Min
0.01
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GSK (GSK) vs. Illumina (ILMN): A comparison of their P/S ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

P/B Ratio (MRQ)

GSK (GSK) at 4.02 is valued about in line with its industry on P/B ratio, while Illumina (ILMN) at 10.30 carries an above-peer premium to book — ILMN is pricier on assets.

GSK

Pharmaceuticals, Biotechnology & Life Sciences industry group

4.02

Max
13.53
Q3
6.54
GSK
4.02
Median
3.25
Q1
1.69
Min
-5.59

ILMN

Pharmaceuticals, Biotechnology & Life Sciences industry group

10.30

Max
13.53
ILMN
10.30
Q3
6.54
Median
3.25
Q1
1.69
Min
-5.59
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GSK (GSK) vs. Illumina (ILMN): A comparison of their P/B ratio against the Pharmaceuticals, Biotechnology & Life Sciences industry group benchmark.

Valuation Metrics

Valuation metrics for GSK (GSK) and Illumina (ILMN)
MetricGSKILMN
P/E Ratio (TTM)17.5436.68
P/S Ratio (TTM)3.017.10
P/B Ratio (MRQ)4.0210.30
Free Cash Flow Yield (TTM)5.28%2.67%